Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06067204Recruiting
Automatic breathing machine during cardiac arrest
This trial tests if using an automatic ventilator during CPR for out-of-hospital cardiac arrest helps with survival. It aims to find better ways to manage breathing support in emergencies.
HsinchuAges 18 years+ - NCT06067438RecruitingPhase 2
Amiodarone to Prevent Irregular Heartbeat After Esophageal Cancer Surgery
This trial tests if amiodarone, a medication that helps keep your heart rhythm steady, can prevent a type of irregular heartbeat called atrial fibrillation after surgery to remove part of your esophagus. If you are having this surgery (called minimally invasive esophagectomy or MIE) for cancer or other esophagus problems, you may be able to join.
Portland, OregonAges 18 years+ - NCT06067789Recruiting
Testing spinal vs. general anesthesia for leg blood flow surgery
This study tests a new way to give anesthesia during leg surgery to improve blood flow. It aims to see if spinal anesthesia works better than general anesthesia for recovery and comfort.
Ottawa, OntarioAges 18 years+ - NCT06068036Recruiting
Telehealth program to boost physical activity after stroke
This study tests whether a telehealth program with a wearable activity tracker can help people who have had a stroke become more active. It's designed for those who are ready to start moving more with their doctor's okay.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT06068764RecruitingPhase 4
Comparing Two Anesthesia Drugs for Bypass Surgery
This study compares two common anesthesia medicines (etomidate and propofol) for patients having planned coronary artery bypass surgery. The goal is to see which medication works better for your heart and recovery.
Hartford, ConnecticutAges 18–90 - NCT06069232Recruiting
Aortic valve disease risk and prognosis study
This study is looking at people with aortic valve disease to understand what factors affect their risk and to build a model that predicts how the disease will progress. Researchers hope this will help doctors better care for patients in the future.
Guangzhou, GuangdongAges 18–100 - NCT06069973Recruiting
Using AI to spot delayed brain injury after a brain bleed
This study uses artificial intelligence (machine learning) and blood tests to find early signs of delayed brain injury after a brain bleed. It aims to help doctors detect and treat this complication sooner.
GothenburgAges 18–110 - NCT06070662Recruiting
New MRI test for small heart vessel disease
This study tests a new way to diagnose small blood vessel disease in the heart using an MRI scan during a stress test. It is for people who are already participating in a larger heart imaging study and are scheduled for a catheter procedure.
Leicester, LeicestershireAges 18 years+ - NCT06070428Recruiting
A study on heart failure care after hospital discharge
This trial tests a new care approach for people with heart failure who are in the hospital or emergency room and planning to go home. The goal is to see if it helps them recover and stay healthy.
Detroit, MichiganAges 18 years+ - NCT06071741Recruiting
Heart stent procedure registry at UMC
This study is a registry that collects information from all patients who get a heart artery stent procedure at the University Medical Center of Ho Chi Minh City. It helps doctors learn more about how these procedures are done and how patients do over time.
Ho Chi Minh CityAges 18 years+ - NCT06071429Recruiting
Dissolvable medicine stent for leg artery disease
This trial tests a new dissolvable stent that slowly releases medicine to keep your lower-leg artery open. It is for people with severe leg pain or small wounds due to poor blood flow, and who are not eligible for other stents.
New York, New YorkAges 18 years+ - NCT06071910Recruiting
Emergency balloon for cardiac arrest outside hospital
This trial tests if placing a special balloon in the main blood vessel (aorta) can help restart the heart after a cardiac arrest that happens outside the hospital. It is for patients who have not gotten a return of pulse even with CPR.
NorwichAges 18–80 - NCT06072690Recruiting
COPD and Heart Health Study
This study looks at how COPD affects your breathing and heart health. It is for people who are newly diagnosed with COPD and have a history of smoking.
Kaunas, Kaunas CountyAges 40 years+ - NCT06073106Recruiting
Frailty prevention study for older Asian adults
This trial tests a program to prevent frailty in people aged 50 and older of Asian descent who have recently been diagnosed with a stroke, traumatic brain injury, knee osteoarthritis, or breast cancer. The goal is to help you stay strong and healthy as you recover.
Singapore, SingaporeAges 50 years+ - NCT06074276Recruiting
Almonds for facial skin collagen and wrinkles
This study tests whether eating almonds can improve collagen and reduce wrinkles on your face. If you are between 35 and 70, maintain your usual diet and skincare, and don't have a nut allergy, you may be eligible.
Sacramento, CaliforniaAges 35–70 - NCT06074549Recruiting
DynamX bioadaptor heart artery trial
This trial studies a new type of device called the DynamX Bioadaptor, which is placed inside a blocked heart artery to help it heal and flex naturally. It is designed for people who need a stent (a tiny tube to open a blocked artery) and may offer a more adaptive option than traditional stents.
PöltenAges 18 years+ - NCT06074731Recruiting
Eye imaging study using a new scanner
This trial uses a special eye scanner to look at eye diseases. It might help doctors see eye problems more clearly.
Linz, Upper AustriaAges 5–110 - NCT06075160Recruiting
RFR-guided heart artery treatment for moderate blockages
This trial uses a special pressure wire called RFR to help doctors decide whether a stent is needed for a moderate heart artery blockage. It aims to make sure only the blockages that really need treatment get stented, which may reduce unnecessary procedures.
Bucheon-si, Gyeonggi-doAges 20–90 - NCT06075251Recruiting
Online support for parents of kids with heart conditions
This study provides an online support program for parents or caregivers of children (ages 3 to 9) who have a congenital heart condition (a heart problem present at birth). The goal is to help you and your child cope and thrive, and you can join from home if you live in Ontario.
Toronto, OntarioAges 3–9 - NCT06075433Recruiting
One year of blood thinners after a GENOSS stent for heart disease
This study tests whether taking two blood thinners for one year after getting a special GENOSS stent is safe and works well for people with coronary artery disease, especially if the stent placement was complex. The goal is to prevent blood clots and keep your artery open.
Wŏnju, Gangwon StateAges 19 years+ - NCT06075628Recruiting
CT scan study after LAA closure procedure
This study looks at long-term outcomes after LAA closure (a procedure to reduce stroke risk) by reviewing CT scans of the device. It aims to learn if blood flow around the device affects healing and future health.
Overland Park, KansasAges 18 years+ - NCT06075602Recruiting
Complex and calcified coronary artery disease: a registry study
This study watches how people with complex or calcified heart artery disease are treated (with stents or bypass surgery) and how they do over time. It aims to learn which treatments work best for tough blockages.
Lucerne, Canton of LucerneAges 18 years+ - NCT06075940Recruiting
A dissolving stent for blocked leg arteries below the knee
This study tests a new bioresorbable scaffold (like a temporary mesh) that slowly dissolves, releasing medication to keep your below-the-knee artery open. It is for people with severely blocked leg arteries causing pain or wounds at rest (Rutherford 4 or 5).
Randwick, New South WalesAges 18 years+ - NCT06076928Recruiting
Brain-computer interface glove for hand recovery after stroke
This trial tests a robotic glove controlled by your brain signals to help improve hand function after a stroke. It is for people who had a stroke at least 16 weeks ago and have some movement in their shoulder and elbow but limited hand control.
Singapore, SingaporeAges 21–85
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.