Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06076551Recruiting
Sex differences in small blood vessel problems of the heart
This study looks at how small blood vessels in the heart work differently in men and women who have chest pain but no major blockages in their main heart arteries. The goal is to better understand and treat these smaller vessel issues.
SeoulAges 20–80 - NCT06078436Recruiting
Early carvedilol for heart failure shock
This trial tests whether starting the heart failure medication carvedilol early, along with standard monitoring, can help people in cardiogenic shock (when the heart can't pump enough blood) due to a weak heart muscle. It aims to see if earlier treatment improves outcomes.
SeoulAges 19 years+ - NCT06078735Recruiting
Device vs manual pressure for closing blood vessels after AFib procedure
This study compares two ways to close the vein entry after heart ablation for AFib: the LockeT device versus manual compression. It helps find which method works better.
Overland Park, KansasAges 18 years+ - NCT06079424Recruiting
Artery aging risk markers study
This study looks at markers of artery aging in people already taking part in the Paris Prospective Study III. It may help understand how arteries change with age.
ParisAges 60–95 - NCT06080178RecruitingPhase 4
Goal-directed fluids during breast reconstruction surgery
This trial tests a precise fluid management strategy during DIEP flap breast reconstruction to improve outcomes. It aims to reduce complications and improve recovery.
Ghent, East FlandersAges 18–70 - NCT06081049RecruitingPhase 2
Colchicine for heart failure with preserved pumping function
This trial is testing whether colchicine, a medication used for gout, can help people with a specific type of heart failure where the heart pumps normally but is stiff. If you have heart failure with preserved pumping and certain signs of inflammation, this study might be a good fit.
HellerupAges 40 years+ - NCT06081010Recruiting
Blood pressure control study in Nepal
This trial tests a program to help people in Nepal lower high blood pressure. It may be a good fit if your blood pressure is 140/90 or higher.
DhulikhelAges 30 years+ - NCT06081062RecruitingPhase 3
Testing Fabagal in people with Fabry disease
This trial is testing a new enzyme replacement therapy called Fabagal for people with Fabry disease who have not had prior treatment. It aims to see if it helps with kidney, heart, or brain problems caused by the disease.
ManilaAges 8 years+ - NCT06081205Recruiting
Heart disease patients in intensive care study
This trial observes patients admitted to the cardiac intensive care unit with acute heart or blood vessel problems. It aims to learn more about their conditions and treatments.
Ioannina, EpirusAges Any age - NCT06081543Recruiting
Ketogenic vs. Mixed Diet for Heart Failure
This study compares a ketogenic (low-carb, high-fat) diet to a standard mixed diet in people with heart failure. It aims to see if the ketogenic diet can improve heart function and symptoms.
Columbus, OhioAges 18–80 - NCT06082284Recruiting
M protein detection study for adult patients
This study is looking for adults at Zhujiang Hospital to test a new, highly sensitive method for detecting a protein called M protein in the blood. It helps doctors understand how common this protein is in different patients.
Guangzhou, GuangdongAges 18 years+ - NCT06082063RecruitingPhase 3
Reducing heart disease risk in type 1 diabetes
This trial tests a combination of treatments to lower the risk of heart disease and kidney problems in people with type 1 diabetes who already have some complications or higher risk. If you qualify, you will receive extra care aimed at preventing heart attacks, strokes, and kidney failure.
CopenhagenAges 40–90 - NCT06082466Recruiting
Comparing two types of leg bypass surgery
This study compares two types of bypass surgery for blocked leg arteries. One uses a standard vein from your own body, and the other uses a vein supported by a special metal frame. The goal is to see which works better and lasts longer.
SalzburgAges 18 years+ - NCT06083168Recruiting
Heart disease in chronic kidney disease study
This study is looking at the link between kidney disease and heart disease. It aims to understand how heart problems affect people with chronic kidney disease. The trial does not test a new drug, but rather follows patients to learn more about their health.
OlsztynAges 18 years+ - NCT06083207RecruitingPhase 1/Phase 2
IBI3003 for multiple myeloma that has returned or not responded
This trial tests an investigational drug called IBI3003 in people with multiple myeloma that has come back or hasn't responded to previous treatments. The goal is to see if it is safe and effective.
Wollongong, New South WalesAges 18 years+ - NCT06083922RecruitingPhase 2
CyBorD plus Daratumumab for kidney disease caused by abnormal proteins
This trial tests a combination of four drugs (CyBorD plus daratumumab) to treat kidney damage caused by abnormal proteins (monoclonal gammopathy). It aims to improve kidney function and reduce protein levels.
Boston, MassachusettsAges 18 years+ - NCT06084052Recruiting
Mobile app study to prevent foot ulcers in diabetes
This trial tests a mobile app to help prevent foot ulcers in people with diabetes who are at high risk. You will use the app to track your foot health and get advice to keep your feet safe.
LondonAges 18–100 - NCT06083948RecruitingPhase 2/Phase 3
Blood pressure medicines and brain blood flow during tumor surgery
This study tests how different blood pressure medicines affect blood flow to the brain and other organs during anesthesia for brain tumor surgery. It aims to find the safest way to keep your brain healthy while you are asleep.
AarhusAges 18–75 - NCT06084962RecruitingPhase 1
GPRC5D-targeted CAR-T cells for advanced multiple myeloma
This trial tests a new type of CAR-T cell therapy that targets a protein called GPRC5D on multiple myeloma cells. It is for people whose myeloma has not responded to or has returned after at least three prior treatments, and aims to see if this targeted approach can help control the disease.
Hangzhou, ZhejiangAges 18–75 - NCT06085612Recruiting
How carotid artery blockage affects blood flow in the retina
This trial examines how a narrowing of the main neck artery (carotid stenosis) impacts blood flow in the retina using a special eye test called automated retinal oximetry. The goal is to better understand how this blockage affects eye health.
OlomoucAges 18 years+ - NCT06088212Recruiting
Heart failure treatment to help thinking and memory
This trial tests whether better managing heart failure after a hospital stay can protect against thinking and memory problems. It is for people who have heart failure and have had some cognitive difficulties.
Hobart, TasmaniaAges 18 years+ - NCT06087367Recruiting
Database study of KCNH2 gene variants
This study is building a database to better understand how different changes in the KCNH2 gene affect health. It may help doctors make more accurate diagnoses and predictions for people with this gene variant.
Nantes, Loire-atlantiqueAges Any age - NCT06087848RecruitingPhase 1/Phase 2
StromaForte stem cell therapy for heart event prevention
This trial tests a stem cell product called StromaForte to see if it can reduce cardiovascular events like heart attacks in people with stable medical conditions. It may help if you have heart or blood vessel issues that have been stable for at least six months.
Nassau, The BahamasAges 25–85 - NCT06089031Recruiting
Belgian registry for coronary function testing
This study collects information from people having tests to check how well the blood vessels in the heart work. It helps doctors learn more about these tests and improve care for future patients.
Deurne, AntwerpAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.