Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06059144RecruitingPhase 3
Raising blood pressure for worsening small artery strokes
This trial tests if raising blood pressure slightly with a low dose of a medicine called norepinephrine can help people whose stroke symptoms are getting worse. It focuses on small, deep brain artery strokes and aims to improve recovery.
BordeauxAges 18 years+ - NCT06059664RecruitingPhase 2
Finerenone for kidney transplant recipients: the EFFEKTOR study
This study tests whether a medicine called finerenone can help protect kidney transplants from further damage. People who have had a kidney transplant and have protein in their urine may benefit from this treatment.
Chapel Hill, North CarolinaAges 18 years+ - NCT06059872Recruiting
Study of high-intensity interval training after stroke
This study tests whether a high-intensity interval training (HIIT) exercise program can help people with walking difficulties after a stroke. It looks for veterans who have had a stroke at least 6 months ago and walk slowly, to see if this type of exercise can improve their recovery.
Decatur, GeorgiaAges 18–89 - NCT06060548Recruiting
New heart monitor to help manage PVCs
This trial tests if a small heart monitor (ILR) made by Medtronic can help doctors better manage premature heartbeats (PVCs). If you already have this monitor, you may be able to join.
Overland Park, KansasAges 18 years+ - NCT06061549RecruitingPhase 1
Gene therapy for stiff heart failure (preserved EF)
This trial tests a one-time gene therapy for people with heart failure who still have normal pumping strength (preserved ejection fraction). It aims to improve how heart cells handle calcium, which may help the heart relax better and ease symptoms.
Durham, North CarolinaAges 50 years+ - NCT06061120Recruiting
Heart rhythm study for ablation patients
This study uses a special ECG to better tell apart different types of fast heart rhythms in people scheduled for a procedure called ablation. The goal is to improve diagnosis and treatment for conditions like atrial fibrillation and other supraventricular tachycardias.
Aachen, North Rhine-WestphaliaAges 18 years+ - NCT06061770Recruiting
Comparing two exercise programs for chronic stroke patients
This trial compares a supervised exercise program in a special facility with a self-guided exercise program at home. It aims to see which is more effective for improving walking and daily activity in people who had a stroke more than 6 months ago.
Marseille, Bouches du RhôneAges 18 years+ - NCT06061627Recruiting
LOT-CRT vs standard CRT for heart failure with NICD
This study compares a newer pacing therapy (LOT-CRT) to standard cardiac resynchronization therapy (BiVP) for people with heart failure who have a specific type of electrical delay in the heart (NICD). The goal is to see if the newer method works better.
Nanjing, JiangsuAges 18–80 - NCT06061757Recruiting
Combining 4D-ICE and TEE imaging for heart closure
This trial tests a new imaging method (4D-ICE) used alongside a standard ultrasound (TEE) during a heart procedure to close the left atrial appendage, a small pouch in the heart where clots can form in people with atrial fibrillation. The goal is to see if the new method makes the procedure safer and more precise.
Overland Park, KansasAges 18–80 - NCT06062576RecruitingPhase 4
Yunnan Baiyao for diabetic foot ulcers
This study tests whether Yunnan Baiyao, a traditional Chinese medicine, helps heal diabetic foot wounds at different stages. It aims to see if it can reduce infection and promote new tissue growth.
Beijing, Beijing MunicipalityAges 18–80 - NCT06061822Recruiting
Testing AI for better heart MRI scans
This trial is testing a new artificial intelligence system that helps doctors take clearer, faster heart images using MRI. It aims to make heart scans more accurate and comfortable for patients.
LondonAges 18 years+ - NCT06062394Recruiting
Healthy Heart study for Penn Medicine patients
This trial tests if a combination of medication and lifestyle changes can lower cholesterol and prevent heart problems in people who are at risk or already have heart disease.
Philadelphia, PennsylvaniaAges 35–80 - NCT06062693Recruiting
Home Hand Training with Sensors for Better Dexterity
This study tests a new home-based hand training system using sensors to help improve hand movement and dexterity in people with Parkinson's, multiple sclerosis, or stroke. It also includes healthy volunteers for comparison.
LucerneAges 18–99 - NCT06063564Recruiting
Testing a digital tool to improve heart health in rural clinics
This study is testing a digital health app called PREVENT to help doctors and patients work together on heart-healthy habits like eating well and being active. It is designed for people in rural areas who want to lower their risk of heart disease.
St Louis, MissouriAges 18–64 - NCT06063538RecruitingEarly Phase 1
Preventing irregular heartbeat after heart surgery with amiodarone
This trial tests if placing a small amount of amiodarone medicine near the heart during open-chest surgery can help prevent a common irregular heartbeat (atrial fibrillation) that often happens after heart surgery.
Chicago, IllinoisAges 20–85 - NCT06064825Recruiting
Long-term follow-up for TREOCAPA study children
This study is a long-term check-up for children who were in the TREOCAPA trial. It follows their health and development for about 2 years after they were in the original study.
AngersAges 1.9 years–2.3 years - NCT06065124Recruiting
Study on weight loss surgery for heart failure with irregular heartbeat
This trial tests if weight loss surgery can help people with heart failure and atrial fibrillation (an irregular heartbeat) improve their heart condition. You may join if you are between 45 and 70, have a BMI of 32 to 40, and have mild to moderate heart failure with preserved pumping function.
Arnhem, GelderlandAges 45–70 - NCT06065046RecruitingPhase 2
Baricitinib for traumatic brain bleeding
This trial tests if baricitinib, an anti-inflammatory drug, can help people with bleeding in the brain from a head injury. It is for adults with moderate to severe traumatic brain injury who are not immediately having surgery.
Xi'an, ShaanxiAges 18–80 - NCT06065852Recruiting
National registry for rare kidney diseases
This study creates a registry to collect health information from people with rare kidney diseases. It aims to improve understanding and future treatments by tracking patient experiences.
Bristol, South WestAges Any age - NCT06066801Recruiting
Bedside bone biopsy for diabetic foot infection
This trial is testing a new way to take a small sample of infected bone from the foot of people with diabetes. It aims to see if a bedside biopsy is safe and accurate for diagnosing bone infection, so you may avoid more invasive procedures.
ParisAges 18 years+ - NCT06066268Recruiting
miRNAs in Critical Limb Ischemia Study
This study looks at small molecules called miRNAs in the blood of people with severe leg artery disease (critical limb ischemia) or belly aortic aneurysm. The goal is to find patterns that may help doctors better understand and treat these conditions.
San Donato Milanese, MilanAges 40–85 - NCT06066346RecruitingPhase 2
Talquetamab for multiple myeloma after CAR T-cell therapy
This study tests a drug called talquetamab for people with multiple myeloma who have already had a type of immunotherapy called CAR T-cell therapy (ide-cel). The goal is to see if talquetamab can help control the cancer after the CAR T cells have had time to work.
Basking Ridge, New JerseyAges 18 years+ - NCT06066450Recruiting
OSFIT Stent for Coronary Artery Blockage
This trial tests a special stent (OSFIT) in people with a blockage near the start of a coronary artery. The goal is to see if the stent works well for this specific location.
SuwonAges 19 years+ - NCT06066970Recruiting
Studying heart markers after valve surgery
This trial uses a special MRI and blood tests to see how heart muscle is affected after aortic or mitral valve surgery. It may help doctors better understand and monitor heart recovery.
Freiburg im Breisgau, Baden-WurttembergAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.