Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06238050Recruiting
Oxygen therapy for severe leg artery disease
This trial tests whether breathing pure oxygen at normal pressure can help people with severe, long-lasting lack of blood flow in their legs. It may offer a way to improve oxygen delivery to the leg and possibly avoid amputation.
AngersAges 18 years+ - NCT06241482Recruiting
Enhanced recovery after brain surgery in intensive care
This study tests a special recovery program for people with serious brain injuries or strokes who need intensive care. The program focuses on helping you heal faster after surgery.
ShanghaiAges 18–75 - NCT06241677Recruiting
Clot-busting therapy for stroke patients on blood thinners
This study tests whether giving a clot-busting medicine through an IV can help people who have had a stroke while taking a common blood thinner (apixaban, dabigatran, edoxaban, or rivaroxaban). It may be an option if your last dose of the blood thinner was 12 to 48 hours before the stroke and you arrive at the hospital within 4.5 hours of symptoms starting.
Hong KongAges 18 years+ - NCT06241651Recruiting
Comparing two types of pacemakers for heart failure patients
This trial tests if a new pacemaker method (CSP) works better than the standard method (BiVP) for people with heart failure who already have a right ventricular pacemaker and need an upgrade.
Nanjing, JiangsuAges 18–80 - NCT06242366Recruiting
Transitional care program for stroke recovery
This trial tests a transitional care program for people recovering from a first-time stroke that caused weakness on one side of the body. The program is designed to help you manage your recovery at home after leaving the hospital.
Bang Kho Laem, BangkokAges 18 years+ - NCT06243653Recruiting
Heart microvessel function test for heart failure recovery
This trial looks at how tiny blood vessels in the heart affect improvement in heart pumping strength for people with heart failure. It tests whether a special procedure during heart catheterization can predict recovery.
SeoulAges 19 years+ - NCT06244199Recruiting
Starting cardiac rehab in the hospital for Veterans
This study tests a program that starts cardiac rehab in the hospital for Veterans with various heart conditions. The goal is to make rehab easier to begin, especially for those with other health issues or frailty.
Boston, MassachusettsAges 18 years+ - NCT06244732Recruiting
Pain control after open aneurysm surgery
This study tests two different ways to manage pain after open surgery for an abdominal aortic aneurysm. It compares a standard pain control method to another approach that may reduce the need for strong painkillers.
San Donato Milanese, MilanAges 18 years+ - NCT06244914Recruiting
Combined brain stimulation for recovery after recent stroke
This trial tests if combining two kinds of gentle brain stimulation can help people recover better after a recent stroke. It's for people who had a clot-caused stroke in the upper part of the brain and still have some weakness on one side.
Tainan, TainanAges 18 years+ - NCT06244940Recruiting
Genetic testing study for heart defects in pregnancy
This study tests a new way to find genetic causes of congenital heart disease (a heart problem found before birth) using samples from amniocentesis or chorionic villus sampling. It may help parents get a clearer diagnosis and plan for their baby's care.
San Diego, CaliforniaAges 18 years+ - NCT06245187Recruiting
Atrial Fibrillation In-Hospital Registry
This registry study collects information on people hospitalized for atrial fibrillation or atrial flutter (types of irregular heartbeats) to help doctors learn how to improve care. By joining, you help researchers understand what treatments work best.
Dallas, TexasAges 18–125 - NCT06245629Recruiting
Comparing two drug combos for relapsed multiple myeloma
This trial looks at two different drug combinations given before a second stem cell transplant for multiple myeloma that has come back after first treatment. It aims to see if adding two extra drugs (bortezomib and bendamustine) to the standard drug (melphalan) works better than using the standard drug alone.
UppsalaAges 18 years+ - NCT06246162RecruitingPhase 1/Phase 2
Mitoxantrone liposome combo for high-risk multiple myeloma
This trial tests a liposomal form of mitoxantrone combined with other drugs for people with aggressive multiple myeloma (high-risk or spread outside the bone). The goal is to see if this approach helps control the cancer better.
Nantong, JiangsuAges 18–70 - NCT06247189Recruiting
ICOPE program for older adults with myeloma
This trial tests whether a program called ICOPE MONITOR, which uses a smartphone app or chatbot, can help older adults with multiple myeloma stay healthier and manage their care. It may be a good fit if you are 70+ and starting your first or second treatment.
ToulouseAges 70 years+ - NCT06247553Recruiting
Walking exercise program for stroke survivors who can't walk
This study aims to develop a walking exercise program for people who have had a stroke and cannot walk on their own. It will test a treadmill-based program to help improve walking ability.
Kansas City, KansasAges 18–80 - NCT06248593RecruitingPhase 4
Continuous Norepinephrine vs Phenylephrine for Cesarean Blood Pressure
This study compares two medicines (norepinephrine and phenylephrine) given continuously through a vein to keep your blood pressure stable during a planned cesarean with spinal anesthesia. It aims to see which medicine works better for you and your baby.
FesAges 18–45 - NCT06249269Recruiting
Lifestyle Change to Improve AF Ablation Results
This trial tests whether a healthy lifestyle program (including exercise and weight loss) can help people with atrial fibrillation (AF) who are overweight or have related health risks. You will have a catheter ablation procedure, and the study will see if lifestyle changes improve your heart's rhythm long-term.
Calgary, AlbertaAges 18 years+ - NCT06249035Recruiting
Ultrasound Probe Study During Cardiac Arrest in ER
This study tests whether it is possible to use a special ultrasound probe down the throat (TEE) during a cardiac arrest in the emergency department. It aims to help doctors see the heart better while trying to save someone's life.
Leeuwarden, Provincie FrieslandAges 18 years+ - NCT06249347Recruiting
New ablation approach for persistent atrial fibrillation with stroke risk
This trial tests a new type of catheter ablation (using heat to create scar lines in the heart) for people with persistent atrial fibrillation who have a higher risk of stroke or bleeding. It aims to see if this approach can help prevent strokes and reduce the need for long-term blood thinners.
Wenzhou, ZhejiangAges 18 years+ - NCT06249945RecruitingPhase 4
Empagliflozin for heart failure with preserved ejection fraction and dialysis
This trial tests whether a medicine called empagliflozin (used for diabetes and heart failure) can help people with both heart failure (with preserved pumping ability) and end-stage kidney disease who are on dialysis. The study looks at how the drug affects heart function and overall well-being.
HsinchuAges 20 years+ - NCT06250985RecruitingPhase 3
New treatment for infected heart device: quick re-implant
This trial tests if a new, faster approach to replacing an infected pacemaker or defibrillator is safe. If you have a heart device infection and meet recovery milestones, you might be able to get a new device sooner than usual.
CopenhagenAges 18–110 - NCT06250257RecruitingPhase 3
Bromocriptine for Heart Weakness in Women 18-50
This trial tests a medicine called bromocriptine to see if it helps women with a weak heart muscle (dilated cardiomyopathy). It is for women between 18 and 50 whose heart weakness was found recently or is caused by blocked arteries, and who are not pregnant or planning pregnancy.
Jimma, OromiyaAges 18–50 - NCT06250595Recruiting
European rare blood disorder registry
This study is building a registry of people with rare blood diseases. By joining, you help doctors learn more about these conditions and improve future care.
Barcelona, CataloniaAges Up to 100 years - NCT06250790Recruiting
Heart Artery Check for Leg Artery Disease Patients
This trial uses a special CT scan (coronary CTA with HeartFlow analysis) to look for hidden blockages in the heart arteries of people who recently had a leg artery procedure. It may help detect heart problems early so they can be treated.
RigaAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.