Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06336174Recruiting
Thinking and Memory in Brain Artery Narrowing: A Study
This study looks at how severe narrowing of brain arteries may affect memory and thinking over time. It involves people who have had a mini-stroke or mild stroke and aims to understand the changes in cognitive function.
Hefei, AnhuiAges 18–80 - NCT06336213Recruiting
Using a blood test to guide antibiotics in aorta surgery
This trial checks if a blood test called presepsin can help doctors decide when to use antibiotics in patients having surgery on the chest's main artery (the thoracic aorta). It is for people with an aneurysm or tear in that artery.
Moscow, MoscowAges 18–75 - NCT06336655RecruitingPhase 2
Studying heart pump therapy for severe heart shock
This trial tests if unloading the heart during ECMO support helps patients recover better from cardiogenic shock. It compares different ways to reduce the heart's workload.
Salt Lake City, UtahAges 18 years+ - NCT06336798RecruitingPhase 2
Pioglitazone for pulmonary hypertension from lung disease
This trial tests if pioglitazone, a medicine used for diabetes, can help people with high blood pressure in their lungs caused by chronic lung disease. The goal is to see if it improves how your cells use energy.
Atlanta, GeorgiaAges 18 years+ - NCT06336746Recruiting
Heart function during steep head-down position in robotic surgery
This study looks at how your heart performs during robotic surgery when you are placed in a steep head-down position. It may help doctors better understand how to keep you safe during the procedure.
Karlstad, Värmland CountyAges 18 years+ - NCT06337227Recruiting
Studying sirtuins as biomarkers for artery or heart valve disease
This study tests whether proteins called sirtuins can be used as biomarkers (biological clues) to better understand patients with hardened arteries (atherosclerosis) or calcified heart valve disease (calcific aortic stenosis), especially if you also have diabetes. It may help doctors develop better ways to diagnose or monitor these conditions.
NaplesAges 18 years+ - NCT06337578Recruiting
Telephone-based cognitive screening study
This study tests if a phone-based cognitive screening can effectively assess thinking and memory. It may help people who can't easily visit a clinic.
MilanAges 18–100 - NCT06338215Recruiting
Moderate drinking vs. abstention advice for adults
This study compares two approaches for adults who drink regularly: advice on drinking in moderation vs. advice to stop drinking entirely. The goal is to see which approach better prevents major diseases and early death over time.
Pamplona, NavarreAges 50–75 - NCT06338293RecruitingPhase 4
Inclisiran plus statins for fragile heart plaque
This trial tests if adding inclisiran to your current statin can reduce dangerous, rupture-prone plaque in your heart arteries. It may help if you have a moderate blockage with thin-cap plaque and your LDL cholesterol stays high despite statins.
Nanjing, JiangsuAges 18–80 - NCT06338696Recruiting
Thailand ATTR-CM patient registry
This registry collects information from people with ATTR-CM, a condition where abnormal protein builds up in the heart. By joining, you help researchers learn more about the disease and improve future care.
BangkokAges 18–100 - NCT06338878Recruiting
Heart failure hospitalization study: tracking long-term outcomes
This study looks at what happens to people after they are hospitalized for heart failure. It tracks their health both in the hospital and after they go home to learn how to improve care.
NancyAges 18 years+ - NCT06340152Recruiting
Studying maternal health after preeclampsia
This trial follows women who have had preeclampsia to learn more about their health after pregnancy. It collects blood and tissue samples to find markers that could improve future care.
San Diego, CaliforniaAges 18–50 - NCT06340516Recruiting
Looking at a blood test to track heart health during HER2 breast cancer treatment
This trial is checking if a simple blood test (NT-proBNP) can help spot early signs of heart side effects from certain breast cancer treatments (chemotherapy plus HER2 blockers). If successful, it might help doctors adjust treatment sooner to protect your heart.
GothenburgAges 18 years+ - NCT06340646Recruiting
Washington University cancer gene study
This study collects genetic information from people with certain cancers to learn more about cancer risks and outcomes. It may help researchers understand how genes affect cancer in different groups.
St Louis, MissouriAges 18 years+ - NCT06340737RecruitingPhase 1
CD22-targeting CAR T cells for relapsed B cell lymphoma
This trial tests whether giving modified immune cells (CAR T cells) that target CD22 on cancer cells can help people with certain B-cell lymphomas that have come back or not responded to at least two prior treatments. The goal is to see if this approach can shrink tumors or control the disease.
Palo Alto, CaliforniaAges 18 years+ - NCT06341166Recruiting
Predicting heart scarring in mitral valve prolapse
This study looks at people with mitral valve prolapse (a common heart valve condition) to see if doctors can predict who might have scar tissue in their heart muscle. If you have this condition, joining could help improve understanding of your heart health.
Milan, MilanAges 18 years+ - NCT06341231Recruiting
Personalized blood thinners for lung clots
This study tests personalized blood thinner treatments for people with blood clots in their lungs. It looks for patients who are older, have kidney problems, or have cancer, to see if adjusting the treatment helps them more.
Changsha, HunanAges 18 years+ - NCT06342206Recruiting
TCM Assessment for Recent Ischemic Stroke
This study uses traditional Chinese medicine (TCM) diagnostic tools to evaluate patients who had an ischemic stroke within the last 10 days. It aims to understand the acute and chronic phases of stroke to help guide future treatments.
ChanghuaAges 20 years+ - NCT06342661Recruiting
VISTA protein in blood vessel-related memory problems
This study measures levels of a protein called VISTA in the blood of people with memory problems caused by blood vessel disease. It aims to see if VISTA can help diagnose or predict this condition.
Harbin, HeilongjiangAges 50–80 - NCT06342635Recruiting
Study of Hydra Heart Valve in Copenhagen
This study is testing a new heart valve system called Hydra, used during a less invasive procedure called TAVI to replace a narrowed heart valve. It may help people with severe aortic stenosis who are already candidates for TAVI.
CopenhagenAges 18–99 - NCT06343259Recruiting
Comparing anesthesia types for hip surgery in older adults
This study compares general anesthesia (you are completely asleep) versus spinal anesthesia (you are awake but numb from the waist down) during hip surgery to see which one is better at preventing heart muscle damage. It is for people 65 and older who are at moderate to high risk for heart problems.
IstanbulAges 65 years+ - NCT06343844Recruiting
Heart attack recovery differences between men and women
This study looks at how men and women recover differently after a first heart attack. By comparing heart function over time, researchers hope to find better ways to treat each gender.
AngersAges 18 years+ - NCT06346886Recruiting
App for blood pressure control in African Americans
This study tests whether a smartphone app can help African American adults with high blood pressure better manage their condition and improve heart health. You'll use the app regularly and share your progress.
Rochester, MinnesotaAges 18 years+ - NCT06347276Recruiting
PFO closure and brain microemboli study
This trial looks at whether closing a small hole in the heart (PFO) can reduce tiny clots traveling to the brain. It includes people who have had a stroke or migraine, and also those without symptoms but with high-risk features.
Beijing, Beijing MunicipalityAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.