Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,989 recruiting studies in this area right now.
By phase
- Not applicable7,969
- Phase 2481
- Phase 4481
- Phase 3447
- Phase 1361
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke845
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke200
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke139
- Pulmonary Hypertension100
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,986 total
- NCT06347796Recruiting
Embolization vs surgery for chronic subdural hematoma
This trial compares a newer, less invasive treatment (embolization) with traditional surgery to treat chronic subdural hematoma (a slow bleed on the brain). It aims to see which approach works better and has fewer side effects.
Phoenix, ArizonaAges 40–90 - NCT06348459Recruiting
Catheter treatment for severe pulmonary embolism
This study looks at how well a catheter (a thin tube) works to treat a serious type of blood clot in the lungs. It is for people who have a large clot that is causing problems like fast heart rate or low blood pressure.
Madrid, MadridAges 18 years+ - NCT06348108RecruitingPhase 1
Talquetamab with iberdomide for relapsed or refractory multiple myeloma
This trial tests a new combination of three drugs: talquetamab (a bispecific antibody), iberdomide (a pill), and dexamethasone (a steroid) for people with multiple myeloma that has returned or become resistant after other treatments. The goal is to see if this triplet is safe and effective at shrinking the cancer.
San Francisco, CaliforniaAges 18 years+ - NCT06348498RecruitingPhase 1
Jia Shen tablets for chronic heart failure study
This trial tests a Chinese herbal tablet, Jia Shen, to see how the body processes it and if it helps people with chronic heart failure. It is for adults with weak heart pumping and stable medication use.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT06349291Recruiting
Blood clots after central line removal in ICU
This study looks at whether removing a central line (a tube in a large vein) in the ICU increases the risk of blood clots. It may help doctors understand how to prevent clots in ICU patients.
Kfar SabaAges 18–99 - NCT06349941RecruitingPhase 3
Heart failure rehab from home using video visits
This study tests whether a home-based cardiac rehab program using video visits and a smartphone app can help people with heart failure recover and feel better. It may be a good option if you have been hospitalized for heart failure recently and want to take part in rehab from home.
Dallas, TexasAges 18 years+ - NCT06350110RecruitingPhase 1/Phase 2
CAR T cells for lupus
This trial tests a new type of CAR T cell therapy for people with active lupus that has not responded to other treatments. It uses specially engineered cells to target and eliminate certain immune cells that are causing the disease, with the goal of reducing symptoms and preventing flare-ups.
Beijing, Beijing MunicipalityAges 18–90 - NCT06350695Recruiting
Compression stockings for heart failure with leg swelling
This trial tests whether wearing compression stockings can help people with heart failure who have leg swelling. Researchers want to see if stockings reduce fluid buildup and improve daily life.
Dallas, TexasAges 18 years+ - NCT06350994Recruiting
Early Heart Check After CAR-T Cell Treatment
This study checks your heart function early after CAR-T cell cancer treatment. It uses a quick heart ultrasound to look for changes soon after the infusion.
ParisAges 18 years+ - NCT06351345RecruitingPhase 2
Xenon imaging study for pulmonary hypertension patients on sotatercept
This trial uses a special imaging technique (xenon MRI) to see how well the lungs are functioning in people with pulmonary arterial hypertension (PAH) who are being treated with the drug sotatercept. It aims to understand if the drug improves lung function.
Durham, North CarolinaAges 18–75 - NCT06352320Recruiting
Improving care for cardiomyopathy patients
This trial aims to better understand and treat cardiomyopathy by studying patients' hearts with advanced tests. It seeks to find new ways to prevent or manage the condition early.
Xi'an, ShaanxiAges 18–80 - NCT06352710Recruiting
Tracking recovery after brain or spine surgery
This study uses a smartphone app to track how you recover after brain or spine surgery. It helps doctors understand how side effects affect your daily life, so they can improve care.
Sankt Gallen, St.GallenAges 18 years+ - NCT06352671Recruiting
Long-Term Outcomes of a Standardized Ross Procedure
This study follows patients who are having a Ross procedure (a type of heart valve surgery) at select hospitals. Researchers will track their health outcomes over a long period to understand how well the surgery works.
Plano, TexasAges 18–90 - NCT06353334RecruitingPhase 4
Butylphthalide for brain recovery after cardiac arrest
This trial tests if butylphthalide can improve brain function in people who have been resuscitated after a cardiac arrest. It may help reduce brain damage and improve recovery.
Beijing, Beijing MunicipalityAges 18–80 - NCT06353594Recruiting
Fewer stents vs usual stents for STEMI heart attack
This study compares using fewer stents versus the usual number of stents during emergency angioplasty for a severe heart attack (STEMI). It aims to see if a less-is-more approach is safe and effective.
Huelva, HuelvaAges 18 years+ - NCT06353568Recruiting
Light therapy to prevent diabetic foot ulcers
This study tests a painless light treatment (photobiomodulation) to see if it can prevent foot ulcers in people with type 2 diabetes who are at risk. If you qualify, you would receive the treatment regularly and be monitored for foot health.
São Paulo, São PauloAges 18–75 - NCT06353607Recruiting
Genetics of aortic aneurysm and dissection
This study looks at the genetic reasons behind aortic aneurysms and sudden aortic tears. By studying people who had surgery at the University Hospital Basel, researchers hope to find inherited patterns that could help predict and prevent these serious conditions.
BaselAges 18 years+ - NCT06354881Recruiting
Blood flow in the brain after lacunar stroke
This study looks at how well-controlled blood pressure and diabetes affect blood flow in the brain after a small type of stroke called lacunar stroke.
Leicester, LeicestershireAges 18 years+ - NCT06355063Recruiting
CellFX device for atrial fibrillation during open-heart surgery
This trial tests a new device called CellFX that uses nanosecond pulsed field ablation to treat atrial fibrillation during open-heart surgery. It may help you if you already need heart surgery and also have AFib.
ViennaAges 18–85 - NCT06356207Recruiting
Measuring heart pause time in fainting during tilt table test
This study tests a new way to measure how long it takes for your heart to pause during a tilt table test, in people with reflex fainting spells. The results may help doctors decide if a pacemaker is right for you.
BolzanoAges 18 years+ - NCT06356727Recruiting
Blood vessel health test for heart recovery
This study checks if tiny blood vessel problems in the heart affect how well the heart muscle recovers after being weak. It uses special imaging during a routine heart catheterization to look at these small vessels.
FerraraAges 18–85 - NCT06356948RecruitingPhase 4
Tranexamic acid speed and blood pressure during planned C-section
This study tests whether giving the drug tranexamic acid (TXA) slowly or quickly during a planned C-section affects your blood pressure. It may help doctors choose the safest way to give this medicine, which is used to reduce bleeding after delivery.
Vancouver, British ColumbiaAges 19 years+ - NCT06357403Recruiting
Predicting blood clots in ICU patients with a blood test
This study looks at whether a blood test measuring a substance called anti-factor Xa activity can help predict dangerous blood clots in critically ill patients. If you join, researchers will follow you to see if the test results can prevent clots.
Graz, StyriaAges 18 years+ - NCT06357416Recruiting
Man Van project: mobile cancer screening for men
This study collects information from men who visit the Man Van, a mobile health clinic that screens for cancers like prostate, testicular, and penile cancers. It aims to learn how well the clinic works and how it can help men catch cancer early.
LondonAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,989 recruiting cardiology studies from the U.S. registry right now, out of 15,300 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.