Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06551129Recruiting
Camzyos treatment in real life: patient experiences
This study tracks how people with obstructive hypertrophic cardiomyopathy feel and function while taking Camzyos (mavacamten). It aims to understand the real-world effects of the medication beyond clinical trials.
Boston, MassachusettsAges 18 years+ - NCT06551402RecruitingPhase 3
Dabigatran vs rivaroxaban for cerebral venous thrombosis
This study compares two blood thinners (dabigatran and rivaroxaban) to see which works better for treating a blood clot in the brain's veins. You may be eligible if you have a new diagnosis of this type of stroke and can start treatment within 14 days.
Kafr ash ShaykhAges 18–75 - NCT06551415RecruitingPhase 3
Comparing two blood thinners for brain vein clots
This trial compares two blood thinners (dabigatran and apixaban) to see which works better for treating a blood clot in the brain's veins. It might help you if you have a new diagnosis of this type of clot and can take oral blood thinners.
Kafr ash ShaykhAges 18–75 - NCT06551597Recruiting
Magnetic field therapy for recent stroke recovery
This study tests whether a very low-frequency magnetic field can help people recover after a stroke. It is for people age 60 and older who had a recent ischemic stroke (clot-caused stroke) within the last two weeks.
PoznanAges 60 years+ - NCT06551805Recruiting
Ferumoxytol for better MRI images in atherosclerosis patients
This study tests whether a special iron-based contrast agent called ferumoxytol can improve MRI images of arteries affected by atherosclerosis. It may help doctors see blockages or inflammation more clearly.
Nanjing, JiangsuAges 18 years+ - NCT06551662Recruiting
Balloon vs. stent for split artery blockages
This trial compares two ways to open a blocked artery that splits into two branches (a bifurcation): using a balloon coated with medicine (drug-coated balloon, or DCB) versus a drug-eluting stent (DES). The goal is to see which approach works better for patients with this type of blockage.
MilanAges 18 years+ - NCT06551714Recruiting
Movement techniques after first open heart surgery
This study tests special movement and breathing techniques to help people recover faster after their first open heart surgery. It focuses on improving health in the early days after surgery.
AnkaraAges 18–75 - NCT06552299Recruiting
Testing how well people measure CPR depth and length
This study compares how accurately laypeople and healthcare providers estimate the depth and length of CPR chest compressions. It helps researchers understand if training or experience affects measurement accuracy.
SeoulAges 18 years+ - NCT06552689Recruiting
Testing Sutra Hemi-valve for leaky mitral valve
This trial tests a new, less invasive heart valve (Sutra Hemi-valve) for people with a leaky mitral valve who cannot have standard surgery. The valve is delivered through a vein in your leg, so you avoid open-heart surgery.
HamiltonAges 18 years+ - NCT06552767Recruiting
Thrombosis and blood vessel inflammation study
This trial aims to learn more about blood clots, inflammation, and blood vessel problems. It may help researchers better understand these conditions and how they affect people.
Bethesda, MarylandAges 5–100 - NCT06552845Recruiting
Heart scan to guide atrial fibrillation treatment
This trial uses a special MRI scan to see if heart scarring matches low-voltage areas detected during catheter ablation for atrial fibrillation. If the scan results are consistent, it could help doctors better plan ablation procedures.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06552910Recruiting
Anesthesia in diabetic foot amputation
This study looks at different types of anesthesia used during foot amputation surgery for people with diabetic foot. It aims to find which method works best for your comfort and safety during the procedure.
Etimesgut, AnkaraAges 18 years+ - NCT06553339RecruitingPhase 1
A study of HS-10516 for VHL syndrome tumors
This trial tests a new drug called HS-10516 in people with VHL syndrome or advanced kidney cancer. The goal is to see if the drug can shrink tumors and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–80 - NCT06553443RecruitingPhase 3
Comparing coated and plain balloons for dialysis access narrowing
This trial tests whether a drug-coated balloon works better than a plain balloon to open up narrowed spots in your dialysis access. If you have a failing AVF with a narrowing that can be treated, this study may help improve your dialysis.
SingaporeAges 21 years+ - NCT06554119Recruiting
Surgery for tricuspid valve leaks after prior heart surgery
This study looks at different surgeries for a leaky tricuspid valve that happened after earlier heart surgery. It may help doctors learn which approach works best for patients like you.
Guangzhou, GuangdongAges 16 years+ - NCT06554340Recruiting
Exercise study for multiple sclerosis with high blood pressure
This study tests if exercise can improve blood vessel health and daily function in people with multiple sclerosis (MS) who also have high blood pressure. It may help you move better and feel better.
Boston, MassachusettsAges 18 years+ - NCT06554665Recruiting
High-Intensity Interval Training for Stroke Recovery
This study tests whether a high-intensity interval training (HIIT) program—short bursts of intense exercise with rest periods—can help improve walking, balance, and daily function in people who have had a stroke. It is for adults who are 50 to 80 years old, had their first stroke 1 to 5 years ago, and can walk at least 10 meters on their own.
KowloonAges 50–80 - NCT06555016Recruiting
Balance training intensity after stroke
This study tests different levels of balance training in people who had a stroke more than 6 months ago. It aims to find the best exercise intensity to improve balance and prevent falls.
Toronto, OntarioAges 20 years+ - NCT06555237RecruitingPhase 2
MEK inhibitors for heart thickening in RASopathies
This trial tests a targeted drug (MEK inhibitor) to treat thickened heart muscle caused by a group of genetic conditions called RASopathies. It may help improve heart function in people with hypertrophic cardiomyopathy.
WarsawAges 1 day–18 years - NCT06555393RecruitingPhase 1
Egg protein health effect pilot study
This study looks at whether a protein from eggs can help people who are at risk for diabetes or who have type 2 diabetes. Participants will eat a special egg product and have their health checked. It compares how healthy people and those with or at risk for diabetes respond.
Edmonton, AlbertaAges 18–70 - NCT06555757Recruiting
Using AI and sound to predict heart failure worsening
This trial uses a smartphone app to record sounds from your chest and breathing. An AI system will analyze these sound patterns to predict when heart failure symptoms might get worse, so you can get help sooner.
Cambridge, CambridgeshireAges 18 years+ - NCT06556043Recruiting
Brain stimulation to improve ankle control in adults with and without stroke
This study uses mild brain stimulation (tDCS) to see if it can help middle-aged and older adults—both healthy and those who have had a stroke—learn ankle movements better. It tests whether stimulating different brain regions can improve motor skills and brain connections.
TaipeiAges 40–80 - NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT06556485Recruiting
Early ablation for heart failure patients with heart pumps or on transplant list
This trial tests whether doing a catheter ablation early (before dangerous heart rhythms start) can help people with severe heart failure who need a heart transplant or already have an ICD. The goal is to see if this can improve outcomes.
Bad OeynhausenAges 18–99
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.