Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,001 recruiting studies in this area right now.
By phase
- Not applicable7,980
- Phase 2482
- Phase 4481
- Phase 3447
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke846
- Heart Failure564
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,998 total
- NCT06556732RecruitingPhase 1
Eplerenone for preventing atrial fibrillation return
This trial is testing whether a medication called eplerenone can help prevent atrial fibrillation (AF) from coming back in people who have structural heart disease and have already had their heart rhythm restored to normal. It may be a good option if you are looking for a way to keep your heart in a normal rhythm.
AsyutAges 20–70 - NCT06556667Recruiting
Comparing two cardioversion methods for persistent AFib
This trial compares two ways of doing cardioversion (a procedure to restore normal heart rhythm) for people with persistent atrial fibrillation. It aims to see if one approach leads to a better recovery and fewer complications.
Ottawa, OntarioAges 18 years+ - NCT06557005Recruiting
Helping new mothers with chronic conditions get primary care
This study helps new mothers with chronic health conditions transition smoothly from pregnancy care to regular primary care. If you have high blood pressure, diabetes, severe obesity, depression, or anxiety, you may be able to join a program that coordinates your care after childbirth.
Boston, MassachusettsAges 18 years+ - NCT06557135Recruiting
Arm vs. Leg Artery for Carotid Stenting
This study compares two ways to reach the blocked neck artery during a stent procedure: through an artery in your arm versus one in your groin. The goal is to see which route is safer and works better for patients who need this treatment.
Nanjing, JiangsuAges 18 years+ - NCT06557616Recruiting
CoolCryo system for treating atrial fibrillation during mitral valve surgery
This trial tests a new tool called CoolCryo that freezes heart tissue to treat atrial fibrillation while you have mitral valve surgery. If you are already having this surgery and also have AF, this device could correct both problems at once.
BydgoszczAges 18 years+ - NCT06557876Recruiting
Pulse field ablation for atrial fibrillation mechanics
This study tests if a new type of energy called pulse field ablation (a procedure that uses short bursts of electric pulses) works as well as standard ablation for restoring normal heart rhythm in patients with episodes of irregular heartbeat. It may help your heart pump more normally.
Paris, FranceAges 18 years+ - NCT06558474Recruiting
Optimizing angioplasty with balloon expansion after stent placement
This trial looks at a technique called post-dilatation, where a balloon is used after placing a stent to make sure it's fully open. It may help people who are having angioplasty (a procedure to open blocked heart arteries). Doctors want to see if using this step more often leads to better results.
Eindhoven, North BrabantAges 18 years+ - NCT06558877Recruiting
Pharmacist-led program for better blood pressure control
This trial tests if a pharmacist-led program with regular follow-ups and support can help people with high blood pressure get better control over their condition. It may be a good fit if you have high blood pressure that is not well controlled despite taking medication.
Xi'an, ShaanxiAges 18–80 - NCT06559033Recruiting
Gene study for multiple myeloma or MGUS patients
This study looks for certain gene changes (GBA/PSAP) in people with multiple myeloma or MGUS. It aims to understand if these genes are linked to the disease, which may help guide future treatments.
RouenAges 18 years+ - NCT06559332Recruiting
Heart artery checks during aortic valve replacement
This study tests different ways to check for blocked heart arteries in patients getting a new aortic valve through a tube in the leg. It aims to find the best approach to guide treatment.
BernAges 70 years+ - NCT06559241RecruitingPhase 3
Arm or leg cuff treatment for large clot stroke recovery
This trial tests whether a simple, non-invasive treatment (repeated inflation of a blood pressure cuff on your arm or leg) can help people recover better after a stroke caused by a large clot. You must be having a mechanical thrombectomy (clot removal) within 24 hours of your stroke.
Suzhou, AnhuiAges 18 years+ - NCT06559436Recruiting
Extending window for clot-busting drug in medium vessel stroke
This trial tests a clot-dissolving drug called tenecteplase given 4.5 to 24 hours after a stroke caused by a blockage in a medium-sized brain artery. It aims to see if waiting longer than usual still helps reduce disability.
Hefei, AnhuiAges 18 years+ - NCT06559475Recruiting
Testing a new aspiration catheter for large vessel stroke
This trial tests a new catheter (Super-Bore 8/7F) to remove blood clots in people having a major stroke caused by a blocked large artery in the brain. The goal is to see if it is safe and effective at restoring blood flow when used within 24 hours of stroke symptoms starting.
Hefei, AnhuiAges 18 years+ - NCT06559891Recruiting
Ultrasound treatment for high blood pressure
This trial tests an ultrasound device that targets nerves around the kidney to lower blood pressure. It may help people whose blood pressure is not well controlled with medication.
Birmingham, AlabamaAges 22–75 - NCT06560047Recruiting
Early catheter ablation for atrial fibrillation with heart failure
This trial tests whether early catheter ablation (a procedure to fix irregular heartbeats) helps people who have both heart failure and atrial fibrillation. It looks at how this treatment affects your heart function and quality of life.
AalborgAges 18–80 - NCT06560203Recruiting
Basilar artery stroke trial for later treatment
This trial tests if endovascular therapy (a procedure to remove a clot) can help people who have had a stroke in the back part of the brain (basilar artery) and can be treated within 72 hours, even if they are not eligible for clot-dissolving medicine. The treatment may improve recovery compared to standard care alone.
Beijing, Beijing MunicipalityAges 18–80 - NCT06560372Recruiting
Bleeding after head injury and brain blood vessel narrowing
This study looks at whether moderate to severe traumatic brain injury with bleeding around the brain can lead to a complication called cerebral vasospasm (narrowing of brain blood vessels). It's being done at Martinique University Hospital to understand how often this happens and how it affects recovery.
Fort-de-FranceAges 18 years+ - NCT06560424Recruiting
Heart and metabolic health study
This trial collects samples and data to study cardiovascular and metabolic health. You may join if you are willing to participate and do not have severe chronic anemia.
Cleveland, OhioAges 18 years+ - NCT06560502Recruiting
Testing new treatments for diabetic foot and leg ulcers
This trial tests whether adding a special treatment (cellular acellular and matrix-like products) to standard wound care helps diabetic foot ulcers and venous leg ulcers heal faster. It may be an option if you have a diabetes-related foot ulcer that hasn't healed with standard care.
Circleville, OhioAges 21 years+ - NCT06560840Recruiting
Diet study for healthy aging in people with HIV
This study tests whether a special diet aimed at improving gut health can help reduce the risk of heart disease in older adults living with HIV. If you are 40 or older, have certain heart risk factors, and are interested in making dietary changes, this study might be a good fit for you.
ShenzhenAges 40 years+ - NCT06560983Recruiting
Blood sugar and stroke outcomes over one year
This study watches how blood sugar levels affect recovery and risks over one year in people who come to the ER with a stroke. It aims to help doctors better manage blood sugar during emergency stroke care.
Kathmandu, BagmatiAges 18 years+ - NCT06561347RecruitingPhase 2
Zanubrutinib with bendamustine and rituximab for untreated Waldenstrom macroglobulinemia
This trial tests a combination of three drugs (zanubrutinib, bendamustine, and rituximab) for people with Waldenstrom macroglobulinemia who have not been treated before. The goal is to see if this combination is safe and effective.
Denver, ColoradoAges 18 years+ - NCT06561854RecruitingPhase 3
Comparing multiple myeloma treatment with and without dexamethasone
This trial tests whether adding dexamethasone to an antibody-based combination therapy works better for multiple myeloma that has come back after previous treatments. If you have had 1 to 3 prior therapies and are eligible for one of two standard drug regimens, this study may help find the best approach for you.
ParisAges 18 years+ - NCT06561867RecruitingPhase 3
Comparing two drugs to prevent another stroke
This trial tests if ticagrelor or cilostazol is better at preventing a second stroke in people who have had their first mild to moderate ischemic stroke. It aims to find which treatment works best within the first 24 hours of symptoms.
Kafr ash ShaykhAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,001 recruiting cardiology studies from the U.S. registry right now, out of 15,328 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
- Women’s health & pregnancy
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- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.