Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,000 recruiting studies in this area right now.
By phase
- Not applicable7,979
- Phase 2483
- Phase 4481
- Phase 3446
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 388
Top conditions
- Stroke845
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma331
- Atrial Fibrillation269
- Ischemic Stroke201
- Atrial Fibrillation (AF)142
- Acute Ischemic Stroke139
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York163
- Florida144
- Minnesota121
- Illinois120
- Maryland120
- Texas118
Recruiting studies9,997 total
- NCT06597331Recruiting
Heart function study for COPD flare-ups
This study looks at how a COPD flare-up might affect the heart in people who haven't had a heart attack or known heart muscle damage before. It uses a simple heart ultrasound to check for stress-related changes.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT06597851Recruiting
Insulin resistance and heart artery health: a study for chest pain patients
This study looks at how insulin resistance affects tiny heart arteries in people who have chest pain and signs of heart stress on tests, but do not have major blockages in their heart arteries. It aims to understand why some people have heart symptoms even when their main arteries appear clear.
Verona, VRAges 18 years+ - NCT06598150Recruiting
Brain mapping study for chronic arm weakness after stroke
This study uses MRI scans to understand how the brain controls arm movement in people who have had a stroke. It aims to help develop better rehabilitation therapies for chronic arm weakness.
Chicago, IllinoisAges 18 years+ - NCT06598241Recruiting
Bioactive glass fiber study for diabetic foot ulcers
This study tests a special glass fiber material (BBFGM) placed on diabetic foot ulcers to help them heal. It is for people with diabetes who have a foot wound that hasn't healed in 4 weeks to 2 years, is a certain size, and may involve deeper tissue or bone.
San Antonio, TexasAges 18–80 - NCT06598280Recruiting
Going home same day vs staying overnight after afib ablation
This trial compares whether it is safe to go home a few hours after a heart procedure for atrial fibrillation (afib) versus staying in the hospital overnight. It will help doctors understand which approach is better for your recovery.
Lübeck, Schleswig-HolsteinAges 18 years+ - NCT06598436Recruiting
Digital coaching for better diabetes or blood pressure control
This study offers a digital health coaching program to help people with poorly controlled diabetes or high blood pressure manage their condition. It works through telehealth tools and is designed for patients at San Francisco Health Network primary care clinics.
San Francisco, CaliforniaAges 18 years+ - NCT06598683Recruiting
Brain stimulation for muscle stiffness after stroke
This study tests whether a gentle, non-invasive brain stimulation (tDCS) can help reduce muscle stiffness and improve arm or leg movement in people who had a stroke. If you have tight or stiff muscles after your stroke, this might be a good option to explore.
Rawalpindi, Punjab ProvinceAges 30–70 - NCT06599931Recruiting
Cerebellum stimulation to improve arm use after stroke
This study tests if a gentle electric current applied to the back of the brain (cerebellum) can help improve arm and hand movement after a stroke. You may qualify if you had a stroke more than 6 months ago and still have some ability to grip with your affected hand.
ParisAges 18 years+ - NCT06600178RecruitingPhase 1
Heart medication for women with chest pain and small vessel disease
This trial tests a diabetes medication called SGLT2 inhibitors to see if it can improve blood flow to the heart and reduce chest pain in women who have small vessel heart disease (microvascular dysfunction) but not blocked large arteries. Participants will take the medication and be monitored for symptom relief and heart function improvements.
Charlottesville, VirginiaAges 18 years+ - NCT06600542Recruiting
Inari VISION registry for patients treated with Inari devices
This registry collects information on people who have already received treatment with an Inari Medical device, such as a catheter used to remove blood clots. It helps doctors learn more about how well these devices work over time.
AnconaAges 18 years+ - NCT06600737Recruiting
Heart health in people with inflammatory diseases
This study looks at how inflammatory diseases (like rheumatoid arthritis or psoriasis) affect heart health. It aims to understand and improve heart disease risk in people with these conditions, whether they have had a heart event or not.
Manchester, Greater ManchesterAges 18 years+ - NCT06600724Recruiting
Testing a placental tissue dressing for diabetic foot ulcers
This study tests a special wound dressing made from a placental tissue (called PpLHACM) plus standard care, compared to standard care alone, to help heal diabetic foot ulcers that have not healed with usual treatment. It is for people with diabetes who have a moderate-sized foot ulcer without infection or exposed bone.
Monroeville, PennsylvaniaAges 18 years+ - NCT05137054RecruitingPhase 1
Linvoseltamab combo for hard-to-treat multiple myeloma
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
La Jolla, CaliforniaAges 18 years+ - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT07691411Recruiting
Smartphone app for stroke recovery support
This study uses a smartphone app to help you manage your recovery after a stroke. It sends you quick questions and tips throughout the day to support your self-care and well-being.
Hong Kong, Hong KongAges 18 years+ - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT07689058RecruitingPhase 2
CAR-T therapy for relapsed or refractory multiple myeloma
This trial tests a CAR-T cell therapy for multiple myeloma that has come back or not responded to at least three prior treatments. It aims to see if this immunotherapy can help control the disease.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT05979168Recruiting
Text message program to help control high blood pressure in Nepal
This study tests whether receiving text messages on your phone can help Nepali adults with high blood pressure better control their condition. The program supports medication use and healthy habits through simple mobile messages.
Kathmandu, BagmatiAges 18–70 - NCT05194111RecruitingPhase 1/Phase 2
Heart medication study for cancer survivors with mild heart weakness
This study tests a heart medication (sacubitril/valsartan) in young cancer survivors whose hearts were weakened by anthracycline chemotherapy but are not yet having heart failure symptoms. It aims to see if the drug can improve heart function and prevent future problems.
Richmond, VirginiaAges 18–120 - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+ - NCT05670132Recruiting
Heart and brain rehab for youth with congenital heart disease
This trial tests a combined heart and brain rehabilitation program for young people with moderate to complex congenital heart disease. The goal is to improve both heart health and thinking skills, such as memory and attention.
BrusselsAges 8–25
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,000 recruiting cardiology studies from the U.S. registry right now, out of 15,336 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.