Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06599931Recruiting
Cerebellum stimulation to improve arm use after stroke
This study tests if a gentle electric current applied to the back of the brain (cerebellum) can help improve arm and hand movement after a stroke. You may qualify if you had a stroke more than 6 months ago and still have some ability to grip with your affected hand.
ParisAges 18 years+ - NCT06600542Recruiting
Inari VISION registry for patients treated with Inari devices
This registry collects information on people who have already received treatment with an Inari Medical device, such as a catheter used to remove blood clots. It helps doctors learn more about how well these devices work over time.
AnconaAges 18 years+ - NCT06600737Recruiting
Heart health in people with inflammatory diseases
This study looks at how inflammatory diseases (like rheumatoid arthritis or psoriasis) affect heart health. It aims to understand and improve heart disease risk in people with these conditions, whether they have had a heart event or not.
Manchester, Greater ManchesterAges 18 years+ - NCT06600724Recruiting
Testing a placental tissue dressing for diabetic foot ulcers
This study tests a special wound dressing made from a placental tissue (called PpLHACM) plus standard care, compared to standard care alone, to help heal diabetic foot ulcers that have not healed with usual treatment. It is for people with diabetes who have a moderate-sized foot ulcer without infection or exposed bone.
Monroeville, PennsylvaniaAges 18 years+ - NCT05137054RecruitingPhase 1
Linvoseltamab combo for hard-to-treat multiple myeloma
This trial tests a new drug called linvoseltamab combined with other cancer treatments for people with multiple myeloma that has stopped responding to standard therapies. It may be an option if you have already tried several treatments and are looking for a new approach.
La Jolla, CaliforniaAges 18 years+ - NCT06352619Recruiting
Lowering blood pressure after clot removal for stroke
This trial tests whether lowering blood pressure soon after a clot-removal procedure for stroke can improve recovery. It is for people whose blood pressure remains high after the procedure.
Sydney, New South WalesAges 18 years+ - NCT07691411Recruiting
Smartphone app for stroke recovery support
This study uses a smartphone app to help you manage your recovery after a stroke. It sends you quick questions and tips throughout the day to support your self-care and well-being.
Hong Kong, Hong KongAges 18 years+ - NCT07691307Recruiting
TruGamma tricuspid valve replacement study
This trial tests a new device called TruGamma to replace the tricuspid valve without open-heart surgery. It is for older adults with severe tricuspid regurgitation who cannot have surgery and still have symptoms despite medication.
Beijing, Beijing MunicipalityAges 65 years+ - NCT05172960Recruiting
Study of a new heart valve for severe aortic stenosis
This trial tests a new version of a heart valve (SAPIEN X4) placed without open-heart surgery. It's for people with severe aortic stenosis who have symptoms like shortness of breath or chest pain.
La Jolla, CaliforniaAges Any age - NCT07689058RecruitingPhase 2
CAR-T therapy for relapsed or refractory multiple myeloma
This trial tests a CAR-T cell therapy for multiple myeloma that has come back or not responded to at least three prior treatments. It aims to see if this immunotherapy can help control the disease.
Rawalpindi, Punjab ProvinceAges 18 years+ - NCT06352632RecruitingPhase 3
Adaptive Stroke Trial Testing New Treatments
This trial is testing different treatments for stroke patients to find which work best. It's designed to adapt over time so new treatments can be added as research progresses.
Sydney, New South WalesAges 18 years+ - NCT03869138Recruiting
Improving physical function after stroke using alternative therapies
This study tests alternative therapies to help improve physical abilities like walking, balance, and arm/leg function after a stroke. It may help if you can follow instructions and safely participate in supervised movement exercises.
Chicago, IllinoisAges 18–90 - NCT05979168Recruiting
Text message program to help control high blood pressure in Nepal
This study tests whether receiving text messages on your phone can help Nepali adults with high blood pressure better control their condition. The program supports medication use and healthy habits through simple mobile messages.
Kathmandu, BagmatiAges 18–70 - NCT05194111RecruitingPhase 1/Phase 2
Heart medication study for cancer survivors with mild heart weakness
This study tests a heart medication (sacubitril/valsartan) in young cancer survivors whose hearts were weakened by anthracycline chemotherapy but are not yet having heart failure symptoms. It aims to see if the drug can improve heart function and prevent future problems.
Richmond, VirginiaAges 18–120 - NCT04968808Recruiting
Find best timing for stent procedure in NSTEMI with multiple vessel disease
This trial compares when to do a stent procedure (PCI) in people with NSTEMI who have disease in more than one coronary artery (non-IRA). It may help doctors choose the safest and most effective timing for treatment to improve outcomes.
GwangjuAges 19 years+ - NCT05670132Recruiting
Heart and brain rehab for youth with congenital heart disease
This trial tests a combined heart and brain rehabilitation program for young people with moderate to complex congenital heart disease. The goal is to improve both heart health and thinking skills, such as memory and attention.
BrusselsAges 8–25 - NCT06279793RecruitingPhase 2
Fish oil for recovery after high-risk heart surgery
This trial tests if giving fish oil through a vein before and after heart surgery can help patients recover faster. It is for people who have a high risk of complications during surgery.
AugsburgAges 18 years+ - NCT05519046Recruiting
Test a heart pacing treatment for Chagas-related heart failure
This study looks at a heart treatment called cardiac contractility modulation in people with Chagas heart disease who have moderate symptoms and weak heart pumping. It aims to see whether this therapy improves heart function and related outcomes in the right patients.
São Paulo, São PauloAges 18–75 - NCT07465653RecruitingPhase 1
Study of HJB647 for heart failure with reduced pumping ability
This trial tests a new medicine, HJB647, in people with heart failure who have a weak heart pump. It aims to see if the drug is safe and well-tolerated. You may qualify if your heart's pumping ability is reduced and you are on a specific standard therapy.
Bradenton, FloridaAges 18–100 - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT07091682Recruiting
A trial of a dissolvable heart stent for long blockages
This trial tests a new type of stent made from magnesium that slowly dissolves over time. It is for people who have a long blockage in a heart artery that has not been treated before and may be a good option for those who are stable and have not had a recent heart attack.
ErfurtAges 18–80 - NCT07687706RecruitingPhase 3
Tegoprazan to prevent stomach problems after stroke
This study tests a stomach-protecting medicine called tegoprazan for people who have had a stroke and are starting antiplatelet therapy. It aims to prevent stomach complications like ulcers or bleeding.
Busan, BusanAges 19 years+ - NCT07109375Recruiting
Long-term study of pegunigalsidase alfa for Fabry disease
This study observes how well the medication pegunigalsidase alfa works over a long period in people with Fabry disease. It helps doctors learn more about managing the condition in everyday life.
ArezzoAges 18 years+ - NCT07220538RecruitingPhase 4
Ginkgo biloba for memory problems after a mild stroke
This trial tests whether adding ginkgo biloba extract tablets to standard stroke care helps improve memory and thinking in people who had a mild stroke. You may join if you are 55 or older, had a mild stroke in the last 1 to 2 weeks, and now have some cognitive difficulties.
AnyangAges 55 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.