Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,008 recruiting studies in this area right now.
By phase
- Not applicable7,984
- Phase 2484
- Phase 4481
- Phase 3449
- Phase 1360
- Phase 1/Phase 2163
- Phase 2/Phase 387
Top conditions
- Stroke846
- Heart Failure563
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease371
- Multiple Myeloma331
- Atrial Fibrillation271
- Ischemic Stroke200
- Atrial Fibrillation (AF)143
- Acute Ischemic Stroke141
- Pulmonary Hypertension101
- Myocardial Infarction99
- Congenital Heart Disease86
- Stroke, Ischemic84
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California467
- Alabama197
- Massachusetts182
- Arizona174
- New York163
- Florida143
- Minnesota121
- Maryland120
- Illinois119
- Texas118
Recruiting studies10,005 total
- NCT06660602Recruiting
Brain function check before and after heart surgery
This study checks how well your brain works before and after heart surgery. It uses safe tests like a CT scan and an EEG to see if surgery affects brain function.
BeijingAges 18–80 - NCT06660719RecruitingPhase 3
New stroke medicine SP-8203 with clot-busting therapy
This trial tests a new medicine called SP-8203 added to standard clot-busting treatment for people having a moderate to severe stroke. The goal is to see if it helps improve recovery and is safe.
BusanAges 19–85 - NCT06661538RecruitingPhase 2
Food referrals to help children with health conditions
This study tests a program that helps families with food insecurity get connected to food resources. It is for children ages 5–18 who are already seen at certain specialty clinics and who receive Medicaid or SNAP.
La Jolla, CaliforniaAges 5 years+ - NCT06661876Recruiting
Heart radiation therapy for heart failure
This trial tests if a low dose of radiation to the heart can help people with advanced heart failure feel better and improve heart function. It is for patients whose heart failure is stable but severe, and who are already on the best medications.
LeuvenAges 18 years+ - NCT06662084Recruiting
Liver enzyme function in people with cardiogenic shock on heart pumps
This study tests whether your liver’s drug-processing enzymes (CYP) work normally during cardiogenic shock when you are on a heart pump like ECMO or Impella®. The goal is to help doctors choose the right medicines for you.
GenevaAges 18 years+ - NCT06662890Recruiting
Heart attack blood oxygen therapy trial
This trial tests if giving extra oxygen to the blood during a heart attack can help heart muscle recover. It is for people having a specific type of heart attack and balloon treatment.
Clydebank, DunbartonshireAges 18 years+ - NCT06662994RecruitingPhase 4
High dose aflibercept for diabetic macular edema after vitrectomy
This trial tests a high-dose version of the drug aflibercept (given as an eye injection) for people with diabetic macular edema who have previously had a vitrectomy surgery. The goal is to see if this higher dose can help reduce swelling and improve vision.
Fullerton, CaliforniaAges 21 years+ - NCT06663358Recruiting
Safety and effectiveness of Elfabrio in Fabry disease patients
This study is for people with Fabry disease who are taking or planning to take the medication Elfabrio (pegunigalsidase alfa). It will look at how safe and effective the treatment is in real-world use.
Birmingham, AlabamaAges 18 years+ - NCT06663631RecruitingPhase 1
Hibernation-like therapy for stroke recovery after clot removal
This trial tests if a hibernation-like therapy can improve recovery after a stroke caused by a large blood clot in the brain. It is for people who are having a stroke and are scheduled for a procedure to remove the clot.
Linyi, ShandongAges 18–80 - NCT06664528Recruiting
Heart health study for adults getting certain chemo
This study tracks the heart health of adults receiving chemotherapy that may affect the heart. It helps doctors understand how to better monitor and protect patients.
Rome, LazioAges 18 years+ - NCT06665386Recruiting
Cooling infusion with clot removal for severe stroke
This study tests whether cooling the brain during clot removal (thrombectomy) can improve recovery after a severe stroke caused by a large blood vessel blockage. Researchers will use blood tests to find markers that may predict who benefits most.
Dalian, LiaoningAges 18–80 - NCT06666361Recruiting
Blood pressure support for older adults in rural areas
This trial tests whether text messages or mobile health tools can help middle-aged and older adults with high blood pressure manage their condition better. It may be a good fit if you have had high blood pressure for at least a year, take medication for it, and are comfortable using a smartphone.
Tainan, TaiwanAges 45 years+ - NCT06666764RecruitingPhase 3
Oxygen therapy for stroke patients transferred for clot removal
This trial tests whether giving high-concentration oxygen (normobaric oxygen) during transfer to a hospital that can remove a blood clot can help people with acute ischemic stroke. It is for patients who are being transferred specifically for endovascular therapy (EVT) to remove a large clot in the brain.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06667258Recruiting
Earpiece to detect heart rhythm problems
This trial tests if a special earpiece can detect heart rhythm problems like irregular heartbeats. It could help you monitor your heart in a simple way.
London, Non-US/Non-CanadianAges 18 years+ - NCT06667752Recruiting
Antibacterial wound dressing for diabetic foot ulcers
This trial tests a new antibacterial wound dressing to see if it helps heal diabetic foot ulcers safely. It may be an option if your ulcer has been there for over 4 weeks and is not severely infected.
Tallinn, HarjuAges 18 years+ - NCT06668389RecruitingPhase 4
Testing a diabetes medicine for repaired tetralogy of Fallot
This study tests a type of diabetes medicine (SGLT2 inhibitor) to see if it can help people who had surgery for tetralogy of Fallot feel better and have stronger heart and lung function. It may be a good fit if you are an adult with repaired tetralogy of Fallot and do not have certain other health problems.
Hong KongAges 18 years+ - NCT06668519Recruiting
brain wave study in children with seizures and other conditions
This study uses a special brain scan (magnetoencephalography, or MEG) to look at brain activity in children with conditions like seizures, brain tumors, autism, and others. It may help doctors learn more about how these conditions affect the brain.
ShanghaiAges 1 month–18 years - NCT06668649Recruiting
Polish fatigue scale study for MS, ALS, or stroke
This study tests a Polish version of a scale that measures how tired people feel. It's for people with MS, ALS, or stroke, or healthy volunteers.
Krakow, Lesser Poland VoivodeshipAges 18 years+ - NCT06668792RecruitingPhase 2
Study of BCD-248 for returning multiple myeloma
This trial tests a new treatment called BCD-248 for people whose multiple myeloma has come back or stopped responding to at least two prior treatments. It aims to see if it is safe and effective.
KaliningradAges 18 years+ - NCT06668831Recruiting
FGF23 and heart rhythm in dialysis patients
This study looks at whether a blood protein called FGF23 is linked to irregular heartbeats in people on long-term hemodialysis (kidney dialysis). It may help doctors better predict heart risks.
LuganoAges 18 years+ - NCT06669299Recruiting
A heart-rhythm test after ablation to guide next steps
This trial uses a non-invasive stimulation test (NIPS) about a week after a successful ablation procedure for ventricular tachycardia (VT). It aims to see if the test can help doctors decide on further treatment to prevent the fast heart rhythm from returning.
Milan, ItalyAges 18 years+ - NCT06669715Recruiting
Physical fitness and heart health in adults
This study looks at physical fitness and blood flow in a wide range of adults. It aims to understand how fitness affects heart health across different people.
LjubljanaAges 18 years+ - NCT06669884Recruiting
New ECG method to quickly sort chest pain in ER
This study tests a new ECG-based technology that may help doctors more quickly sort out the cause of your chest pain in the emergency room. If you have chest pain that needs checking, this tool could help decide how urgent your care is.
Jinan, ShandongAges 18 years+ - NCT06669962Recruiting
Studying heart function in Takotsubo syndrome
This trial aims to understand the chemical and physical changes in the heart's blood vessels during Takotsubo syndrome, a temporary heart condition often triggered by stress. It may help doctors better diagnose and treat this condition.
Turin, TurinAges 18–90
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,008 recruiting cardiology studies from the U.S. registry right now, out of 15,355 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.