Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT07713615Recruiting
Blood clotting markers and heart ultrasound in people with device-detected atrial fibrillation
This study looks at blood clotting markers and heart ultrasound in people who have a heart device that detected brief episodes of irregular heartbeat (atrial fibrillation). It aims to understand how these markers relate to stroke risk.
EsbjergAges 50 years+ - NCT07876544RecruitingPhase 4
New drug plus amlodipine for high blood pressure and early kidney damage
This trial tests a new medicine (sitogilun malate) combined with a standard blood pressure drug (amlodipine) to see if it protects the kidneys in people with early kidney damage caused by high blood pressure. Participation could help prevent further kidney damage while controlling your blood pressure.
Shanghai, ChinaAges 18 years+ - NCT03545477Recruiting
Curved walking training for stroke, Parkinson's and hip fracture recovery
This study tests whether practicing walking in curved paths can help people recovering from a stroke, Parkinson's disease, or a recent hip fracture improve their balance and mobility. If you have one of these conditions and are in a rehabilitation program, this training might make everyday walking easier.
Lissone, Monza E BrianzaAges 18–90 - NCT07876479Recruiting
Comparing kidney nerve treatment times for high blood pressure
This study tests whether the length of time used for a kidney nerve treatment (renal denervation) affects how well it lowers blood pressure. It may help people whose blood pressure is still high despite taking medications.
ShanghaiAges 20–80 - NCT03631628Recruiting
Mirror therapy with gentle nerve stimulation for stroke arm recovery
This study tests whether combining mirror therapy with mild electrical nerve stimulation can help improve arm and hand movement after a stroke. It may be an option if you can move your unaffected arm and have some shoulder and wrist movement on your affected side.
Hong Kong, Hong KongAges 50–85 - NCT07875257Enrolling by invitation
Brain-based therapy for recovery after a left-side stroke
This study tests a new brain-computer system that helps people recovering from a stroke in the left side of the brain. It uses your thoughts to move a device, which may help improve arm and hand movement.
Buenos Aires, EscobarAges 18–65 - NCT06570473RecruitingPhase 2
RV failure treatment trial for pulmonary hypertension patients
This trial is testing two heart medications, empagliflozin and ranolazine, to see if they can improve right heart function in people with pulmonary hypertension and right ventricular failure. Participants will monitor their symptoms using a smartphone or tablet.
Calgary, AlbertaAges 18 years+ - NCT07875335Enrolling by invitation
Traditional Chinese medicine added to standard care for moyamoya disease
This trial tests whether a traditional Chinese herbal formula (Fufang Tongluo Decoction) can improve outcomes when added to aspirin and atorvastatin for people with moyamoya disease, a condition that narrows brain arteries and increases stroke risk. The study aims to see if this combination reduces stroke risk and improves overall well-being.
Nanjing, JaingsuAges 18–60 - NCT07686120RecruitingPhase 3
Baxdrostat for uncontrolled high blood pressure
This trial tests a new medicine called baxdrostat for people whose blood pressure stays high even when they take two or more medicines. It will be added to your current blood pressure pills to see if it helps lower your blood pressure more.
BeijingAges 18 years+ - NCT07830719RecruitingPhase 2
Study of a new drug for heart disease and inflammation
This study tests a new medicine called YMI024 for people with stable coronary artery disease (blockages in heart arteries) and higher than normal levels of inflammation. The drug aims to reduce inflammation and may lower the risk of future heart problems.
Fairhope, AlabamaAges 18–80 - NCT05610085RecruitingPhase 2
Levetiracetam for newborn seizures: dose-finding study
This trial studies how to give levetiracetam to newborn babies with seizures. It’s trying to find a safe dose and see if it can help control seizures in early life.
San Diego, CaliforniaAges Up to 1 month - NCT07490067RecruitingPhase 4
Metoprolol for heart failure: genes and drug response
This trial tests how the drug metoprolol works in people with heart failure and reduced pumping function. It looks at whether your genetic makeup affects how the drug is processed and how well it helps your heart.
Ann Arbor, MichiganAges 18 years+ - NCT07792655Recruiting
Hand therapy at home after stroke
This study tests a therapy program done at home using video calls to help improve hand function after a stroke. It may help you regain better use of your hand if you had a stroke at least 6 months ago.
Ann Arbor, MichiganAges 40–75 - NCT06899750Recruiting
E3 Hypertension: A team program for blood pressure control
This study tests a team-based program to help African American and Latinx people with uncontrolled high blood pressure. You'll use a smartphone app and get extra support from a doctor team to manage your blood pressure better.
Chicago, IllinoisAges 18 years+ - NCT05868616Recruiting
Checking heart resynchronization timing with a noninvasive test
This trial evaluates a noninvasive way to assess who should get Cardiac Resynchronization Therapy (CRT), and to check results after implantation. If you fit the heart rhythm and heart pump criteria, the approach may help confirm whether CRT is appropriate for you.
OsloAges 18–80 - NCT07672860RecruitingPhase 2
UDCA to protect kidneys during partial nephrectomy
This clinical trial is testing whether a medicine called ursodeoxycholic acid (UDCA) can help protect the kidneys during partial nephrectomy (removing only the tumor while keeping the healthy part of the kidney). It is for people with early-stage kidney tumors who will have temporary interruption of blood flow to the kidney during surgery.
Nanjing, JiangsuAges 18–75 - NCT05733416Recruiting
FDG PET/CT scan after unexplained stroke to find hidden cancer
This study checks whether doing an intensive scan using FDG PET/CT shortly after a “cryptogenic” (unexplained) ischemic stroke can uncover an underlying cause, such as cancer. If a hidden source is found earlier, it may help guide the next treatment steps.
Calgary, AlbertaAges 18 years+ - NCT07792226Recruiting
Stomach procedure for weight loss (ESG with fundal ablation)
This study tests a new procedure called endoscopic sleeve gastroplasty with fundal mucosal ablation to help with weight loss. It is an option for people with obesity who have not had success with other methods and who have not had prior stomach surgery.
Morgantown, West VirginiaAges 18 years+ - NCT07005050Recruiting
Kidney nerve treatment for high blood pressure pilot study
This study tests a new treatment that uses a device to calm overactive nerves in the kidneys, which may help lower high blood pressure. It is for people who are already taking at least two blood pressure medications and still have high readings.
Birmingham, AlabamaAges 21–80 - NCT07690046Recruiting
Cardiac rehab after abdominal aortic aneurysm repair
This study looks at whether a supervised exercise and heart rehabilitation program helps people recover better after surgery to fix an abdominal aortic aneurysm (a bulging, weak spot in the main artery in the belly). It aims to improve heart health and overall recovery.
Innsbruck, TyrolAges 18 years+ - NCT07639853Enrolling by invitation
Doctor feedback survey on Concerto Versa coils
This study gathers feedback from doctors who use Concerto Versa detachable coils (small metal devices that help treat brain aneurysms). The survey helps improve how these coils work and are used.
Piscataway, New JerseyAges 22 years+ - NCT07676578Recruiting
Virtual reality walking rehab for recent stroke patients
This study tests if using a virtual reality headset during walking exercises can help people who had a stroke within the past 1 to 6 months improve their walking. You might be able to join if you can walk a bit but still need help or practice, and your doctor approves.
Indianapolis, IndianaAges 18 years+ - NCT05490238Recruiting
Wrist vs arm access for complex heart procedures
This study compares using the wrist (radial artery) versus a different access site (conventional radial access approach) during complex, larger “bore” heart procedures to open blocked coronary arteries. It aims to see which approach is safer and works better for challenging cases like chronic blockages or heavily calcified arteries.
ArlonAges 18 years+ - NCT07835828Recruiting
Optimised heart and kidney protection for chronic kidney disease and heart disease
This study tests a new approach to protect the heart and kidneys in people with both chronic kidney disease and heart or blood vessel problems. By optimising treatment, researchers hope to reduce the risk of further kidney or heart damage.
SvendborgAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.