Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06903078Recruiting
Shingles and Dementia Risk Study
This study looks at whether the virus that causes shingles (herpes zoster) might increase the risk of dementia. Participants with a fresh shingles rash will give blood samples and attend several follow-up visits over one year.
Houston, TexasAges 18 years+ - NCT06903442Recruiting
Helping ER chest pain patients understand heart risk
This study is testing a new way to talk with people about their heart health after they come to the Emergency Room with chest pain. It aims to help you understand your risk and what you can do to prevent future problems.
EdinburghAges 18 years+ - NCT06903559RecruitingPhase 1/Phase 2
Roxadustat for heart and nutrition in dialysis patients
This study tests whether roxadustat can help improve heart health, nutrition, and reduce inflammation in people on hemodialysis. It may offer a new treatment option for anemia related to kidney disease.
Al Mansurah, DakahliyaAges 18 years+ - NCT06903845Recruiting
Apixaban study for atrial fibrillation
This trial tests whether apixaban, a blood thinner, works well for people with atrial fibrillation who also have heart or circulation conditions. It uses a smartphone app to help track your treatment.
Seongnam, GyeonggidoAges 19 years+ - NCT06903897Recruiting
Social Needs Screening for Chronic Disease Study
This study looks at how asking about social needs (like food, housing, or money worries) can help people with chronic conditions like high blood pressure, diabetes, asthma, or depression. It takes place in Family Medicine clinics and aims to improve overall health.
Worcester, MassachusettsAges Any age - NCT06904768Recruiting
Shoulder sling effect on balance and walking after stroke
This study tests whether using a shoulder sling helps improve balance and walking ability in people who had a stroke within the last 6 months and have one-sided arm weakness. It aims to see if the sling can make moving around safer and easier.
Koropí, AtticaAges 18 years+ - NCT06906367Recruiting
Long-term study of Fabry disease treatments in the US
This study looks at how well available Fabry disease treatments (like migalastat or ERT) work over time in real life. It may help doctors understand who benefits most from these medicines.
Birmingham, AlabamaAges 18 years+ - NCT06906432Recruiting
Brain-Heart Injury After Brain Bleed Study
This study looks at how a brain bleed can affect the heart. Researchers hope to understand the link between brain and heart injury to help improve care for people who have had a brain bleed.
Beijing, Beijing MunicipalityAges 18–80 - NCT06906588Recruiting
Robot arm therapy for arm recovery after stroke
This study tests if using a robot to help with arm exercises can improve arm movement in people who had a stroke less than 6 months ago. The therapy is for the weaker arm and aims to help you regain strength and control.
Cassino, ItalyAges 18 years+ - NCT06906926Recruiting
Studying the Harmony heart valve for long-term safety
This study is following people who get the Harmony valve to see how well it works over time. The valve helps blood flow from the heart to the lungs in people with certain heart conditions.
CopenhagenAges Any age - NCT06907147Recruiting
Renal denervation for uncontrolled high blood pressure
This trial tests a procedure called renal denervation to lower blood pressure in people whose medication isn't enough. It uses a special catheter to calm nerves near the kidneys that may be overactive.
Stanford, CaliforniaAges 18–80 - NCT06907862Recruiting
SWITCH trial: swapping processed soy foods in a heart-healthy diet
This study tests whether swapping highly processed soy foods for less processed soy foods, as part of a heart-healthy diet, can improve blood pressure, blood sugar, and weight in adults with obesity and high blood pressure. It may be a good option if you have type 2 diabetes and are already on stable medications.
Toronto, OntarioAges 18 years+ - NCT06908499Recruiting
Long-term follow-up of a stent study for chronic total occlusions
This study looks at the long-term (10-year) outcomes of a specific stenting technique for patients with a chronic total occlusion (a complete blockage that has been there for at least 3 months) in a major heart artery. It aims to see how well the procedure works over time.
Pune, MaharashtraAges 19 years+ - NCT06908590Recruiting
Community health worker help for heart rehab after a heart event
This trial tests whether a community health worker (a trained person from your community) can help people with low income join and stick with a heart rehab program after a heart event. The goal is to make heart recovery easier and more accessible.
Baltimore, MarylandAges 21 years+ - NCT06908629Recruiting
Helping Detroit cancer survivors with social needs
This study looks at how social needs (like finding enough food) affect cancer survivors in the Detroit area. If you join, researchers will work to connect you with resources that might help.
Detroit, MichiganAges 18 years+ - NCT06908759Recruiting
Fall risk in older adults after heart rehab
This study looks at whether a special cardiac rehab program can help older adults who recently had a heart event improve their balance and reduce their risk of falling. It's designed for people age 65 and older who are now stable enough to begin rehab.
Rome, RMAges 65 years+ - NCT06909240Recruiting
Walking training after first leg blood clot: a study
This study tests whether a progressive walking program helps people recover better after their first leg blood clot (DVT). You would be part of a walking training group and researchers will see if it improves walking ability and leg symptoms.
Hvidovre, Capital RegionAges 18 years+ - NCT06909682Recruiting
AI monitoring with wearables for chronic heart failure
This trial tests an AI system that uses wearable devices and mini-invasive tools to monitor people with chronic heart failure. The goal is to detect changes early and help manage the condition at home.
SalernoAges 19 years+ - NCT06909773Recruiting
COPD testing in people with heart disease
This study looks for undiagnosed COPD in people with heart conditions like coronary heart disease, atrial fibrillation, or chronic heart failure. If you have heart disease and are over 40, you may join to see if you also have COPD and benefit from combined care.
AnqingAges 40 years+ - NCT06910124RecruitingPhase 2
Testing linvoseltamab with lenalidomide for multiple myeloma
This trial tests adding a new drug, linvoseltamab, to the standard maintenance therapy lenalidomide for people with newly diagnosed multiple myeloma. The goal is to see if it can deepen responses or turn a relapse back to a negative minimal residual disease (MRD) state, where no cancer cells are detectable.
Miami, FloridaAges Any age - NCT06910436Recruiting
AI timing and outcomes in heart attack study
This trial uses artificial intelligence to analyze ECG results and timing in patients with a type of heart attack called Non-STEMI (where the artery is narrowed but not fully blocked). The goal is to see if AI can help predict damage and outcomes, which could lead to better care.
Bolzano, BZAges 18 years+ - NCT06911099Recruiting
Studying mitral valve repair for atrial regurgitation
This trial tests a minimally invasive procedure (transcatheter edge-to-edge repair) to fix a leaky mitral valve caused by an enlarged atrium, not by heart muscle damage. It might be an option if your mitral regurgitation is related to atrial issues and your heart's pumping strength is normal.
The Bronx, New YorkAges 18 years+ - NCT06911294Recruiting
Personalized Heart Prevention Study
This study tests new, personalized ways to prevent heart disease in people with metabolic syndrome. It aims to see if custom approaches can lower your risk of heart attacks and strokes.
Rome, ItalyAges 40–69 - NCT06911710RecruitingPhase 1/Phase 2
Car-T therapy for relapsed blood cancers
This trial tests whether CAR-T cells, a type of immunotherapy that targets specific markers on cancer cells, can treat blood cancers that have come back or not responded to standard treatment. It may offer a new option for people with lymphoma, leukemia, or multiple myeloma.
Tianjin, Tianjin MunicipalityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.