Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,049 recruiting studies in this area right now.
By phase
- Not applicable8,023
- Phase 2486
- Phase 4480
- Phase 3451
- Phase 1361
- Phase 1/Phase 2161
- Phase 2/Phase 387
Top conditions
- Stroke854
- Heart Failure568
- Hypertension401
- Cardiovascular Diseases390
- Coronary Artery Disease372
- Multiple Myeloma330
- Atrial Fibrillation272
- Ischemic Stroke199
- Atrial Fibrillation (AF)145
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction99
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California468
- Alabama199
- Massachusetts182
- Arizona176
- New York165
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas119
Recruiting studies10,046 total
- NCT06911671Recruiting
VR and brain stimulation for arm recovery after stroke
This study tests a combination of virtual reality therapy and brain stimulation to help people recover arm movement after a stroke. It uses a special interface controlled by muscle signals and applies stimulation to the cerebellum to improve motor control.
Roma, RomeAges 18–80 - NCT06911736Recruiting
Does head-down position after surgery reduce chronic subdural hematoma recurrence?
This study tests whether placing patients in a head-down position (Trendelenburg) after surgery for a chronic subdural hematoma reduces the chance of the hematoma coming back. It may help people who are already scheduled for surgery to drain the blood collection.
Medellín, AntioquiaAges 18 years+ - NCT06912009Recruiting
How long to treat blood clots in the lungs
This trial looks at how long people need blood-thinning medicine after a serious blood clot in the lungs. It might help doctors find the best treatment length for each person.
StrasbourgAges 18 years+ - NCT06913127Recruiting
High-intensity exercise for better recovery after stroke
This trial studies whether doing high-intensity exercise helps people recover walking and other skills better than usual therapy after a stroke. It is for people who are already in a rehabilitation hospital and can walk a short distance with help.
SingaporeAges 21–99 - NCT06914336Recruiting
Liver ultrasound to check fluid buildup in ventilated patients
This trial uses an ultrasound of your liver to see if there is extra fluid or pressure in your veins that might make it harder to breathe. It may help doctors understand how to better manage the breathing machine for people who have been on it for more than a day.
BrestAges 18 years+ - NCT06914570Recruiting
Heart device effect on tricuspid valve and right heart
This study looks at how a new pacemaker or defibrillator (CIED) might affect the tricuspid valve and the right side of the heart. It aims to understand these changes over time.
Milan, MIAges 18 years+ - NCT06914778Recruiting
How diabetes affects the eyes in South Wales
This study looks at how fat and sugar levels in the blood relate to different stages of eye damage in people with type 2 diabetes. It may help find new ways to treat or prevent vision loss.
Llanelli, WalesAges 18–80 - NCT06915220Recruiting
ADAPT heart rehab app study
This study tests if a smartphone app can help you stay active after finishing cardiac rehab. You might qualify if you own a smartphone and recently completed heart rehab at Michigan Medicine.
Ann Arbor, MichiganAges 18 years+ - NCT06915545Recruiting
Studying a new stent graft for type B aortic dissection
This trial tests a special stent graft for people with a type B aortic dissection that needs a new blood flow path to the left subclavian artery. The device is placed in the aortic arch to repair the tear and keep blood flowing normally.
ChangshaAges 18–80 - NCT06915584Recruiting
Drug management study for heart failure
This study looks at how medications are managed in people with heart failure, especially those who have been in the hospital recently for worsening symptoms. It aims to improve treatment strategies.
Rome, RMAges 18 years+ - NCT06915597Recruiting
Drug-coated balloons for coronary artery disease
This trial is studying how well drug-coated balloons work for people with coronary artery disease. It looks at their use in many different situations, including new blockages, re-narrowed stents, and complex cases. The goal is to see if they are a good option for opening blocked arteries.
DenizliAges 18 years+ - NCT06915792RecruitingPhase 4
Postpartum blood pressure medication and stopping study
This trial compares two blood pressure medicines, nifedipine and labetalol, to see which works better for new mothers with high blood pressure after giving birth. It aims to find the best way to safely stop medicine as blood pressure improves.
Los Angeles, CaliforniaAges 18–64 - NCT06916663Recruiting
Upper body vs. combined exercise during diabetic foot ulcer treatment
This trial compares two exercise programs for people with diabetic foot ulcers: one that uses only upper body exercises and one that combines upper body with non-weight bearing lower body exercises. The goal is to see which approach helps healing while keeping weight off the foot.
CairoAges 18–65 - NCT06917066Recruiting
Registry for severe aortic stenosis patients getting a specific TAVR valve
This study tracks patients with severe aortic stenosis who receive the Myval transcatheter heart valve during TAVR (a less-invasive valve replacement). It aims to understand how well the valve works over time.
Valladolid, ValladolidAges 18 years+ - NCT06917131Recruiting
Can royal jelly help with high blood pressure?
This study tests if taking royal jelly, a natural substance made by bees, can reduce inflammation and stress in the body for people with high blood pressure (stage 1). It may help control blood pressure better.
Rio de Janeiro, Rio de JaneiroAges 18–75 - NCT06917378Recruiting
Study on blocked heart arteries over 3 months
This trial tests a procedure for people with a completely blocked heart artery that has been present for at least 3 months. It aims to see if opening the blockage can improve blood flow and heart function.
New Taipei CityAges 20–120 - NCT06917586Recruiting
Mosaic mitral valve study for patients under 65
This study looks at long-term results in people under 65 who received a specific type of replacement heart valve (the Mosaic mitral valve) during surgery at ProMedica Toledo Hospital. It aims to understand how well the valve works over time.
Toledo, OhioAges 18–65 - NCT06917664RecruitingPhase 4
Treating moderate mitral regurgitation in heart surgery patients
This trial looks at how to treat moderate mitral regurgitation (a leaky heart valve) in people who are already having coronary artery bypass surgery (CABG). It aims to find the best way to manage this condition to improve heart function.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06918002RecruitingPhase 3
Comparing elranatamab with standard care for newly diagnosed multiple myeloma
This trial tests if adding the immunotherapy drug elranatamab (with or without lenalidomide) after initial treatment works better than the usual care for people with newly diagnosed multiple myeloma who are eligible for a stem cell transplant.
AmiensAges 18–69 - NCT06918795Recruiting
Fontan Fitness Trial: Home exercise for better heart health
This study tests whether a home-based exercise training program can improve fitness in people with Fontan circulation. Participants will do regular aerobic exercise and be monitored for changes in heart and lung function over time.
Philadelphia, PennsylvaniaAges 10–17 - NCT06918964Recruiting
Ear nerve stimulation for recent brain bleed
This trial tests a gentle electrical ear stimulation device (taVNS) to see if it helps people recover after a recent brain bleed. It is for adults who had a specific type of bleed within the last 3 days and are generally stable otherwise.
Beijing, Beijing MunicipalityAges 18–80 - NCT06919003RecruitingPhase 2
Improving kidney transplant with a single injection of a protective protein
This trial tests whether a single injection of C1 esterase inhibitor into a donated kidney during preservation can improve transplant outcomes. It is for adults on dialysis waiting for a deceased-donor kidney who meet specific blood and tissue matching requirements.
Los Angeles, CaliforniaAges 18–75 - NCT06919302Recruiting
Digital heart health app for heart disease patients
This study tests a digital heart health app combined with lifestyle coaching to help people with heart disease or diabetes manage their cholesterol and overall heart health. It aims to see if the app can improve outcomes for people already taking a statin.
Toronto, OntarioAges 45 years+ - NCT06920030Recruiting
Testing a new heart device for heart failure
This trial tests a new device that delivers a gentle electrical current to the heart to improve its pumping strength. It is for people with a certain type of heart failure caused by weak heart muscle, not a blocked artery.
Banja Luka, Republic of SrbskaAges 18–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,049 recruiting cardiology studies from the U.S. registry right now, out of 15,440 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.