Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,062 recruiting studies in this area right now.
By phase
- Not applicable8,033
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure567
- Hypertension402
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension103
- Myocardial Infarction98
- Congenital Heart Disease86
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic95
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital53
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California466
- Alabama199
- Massachusetts182
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Minnesota120
- Texas120
Recruiting studies10,059 total
- NCT02097758Recruiting
3D heart ultrasound to guide a device closure for ASD
This trial looks at whether a special 3D ultrasound picture helps doctors safely place a small device to close an atrial septal defect (ASD), a hole in the heart’s upper chambers. If you need ASD closure and are suitable for a device, the results could help improve guidance and outcomes.
SeoulAges 18–80 - NCT02026843Recruiting
Testing eye fluid markers in chorioretinal eye diseases
This study looks at substances (“biomarkers”) in the clear fluid inside the eye to better understand several eye conditions that affect vision. Your results may help doctors learn how these diseases work and how treatments might be chosen.
Daegu, KyungsangpookdoAges 20–80 - NCT00084292Recruiting
Registry for stroke in infants and children worldwide
This study collects information from children who have had a stroke or conditions that increase stroke risk. By joining this registry, your child's medical information helps doctors better understand and treat strokes in young patients.
Toronto, OntarioAges Up to 18 years - NCT02042326RecruitingPhase 2
Sirolimus trial for severe arteriovenous malformations
This trial studies whether sirolimus (Rapamune®) can reduce problems from severe arteriovenous malformations (tangled blood vessel connections). It may help shrink the abnormal vessels or improve symptoms, by testing the medicine in people with certain AVM types.
BrusselsAges 2 years+ - NCT01581424Recruiting
Study how kidney findings change in Fabry disease
This study looks at the natural course of Fabry disease in the kidneys and how different kidney test results relate to each other. It may help doctors better understand kidney progression and treatment outcomes, including for people who have or have not had enzyme replacement therapy.
Minneapolis, MinnesotaAges 1–75 - NCT01496625Recruiting
Biobank study for retinal diseases and comparison samples
This study collects and stores blood and eye-related medical information to help researchers better understand retinal diseases, including age-related macular degeneration and diabetic retinopathy. Your samples may also be used to compare people with retinal disease to people without it.
Bethesda, MarylandAges 2–120 - NCT01607502Recruiting
Database study for people with pulmonary hypertension symptoms
This study builds a medical and symptom database for people who have pulmonary hypertension or may be at risk, to better understand the condition. If you choose to participate, your basic health information and symptom history may be recorded and used for research.
GrazAges 18 years+ - NCT00196742Recruiting
Fabry disease registry and pregnancy follow-up
This study collects health information from people with Fabry disease and specifically from pregnant people with Fabry disease. It helps researchers better understand the condition and how pregnancy affects health, using information you already experience in routine care.
Birmingham, AlabamaAges Any age - NCT00912041Recruiting
Test of a brain-to-computer device for quadriplegia
This study tests whether a tiny brain computer interface can help people with quadriplegia (loss of movement in all four limbs) communicate or control technology. It’s mainly a feasibility study, meaning the goal is to see if the device can work safely and reliably in real life.
Sacramento, CaliforniaAges 18–80 - NCT01793168Recruiting
Rare disease registry and history study
This study keeps a registry (a structured list) of people with rare diseases and may also track how the condition changes over time. It can help researchers better understand rare illnesses and find gaps in care, which may improve future treatments.
Sioux Falls, South DakotaAges Any age - NCT01366404Recruiting
FFR-guided heart procedure study for coronary artery narrowing
This study follows people who have narrowed heart arteries and have a pressure test (FFR) to guide treatment. It may help doctors understand the course of disease when using FFR and choosing a minimally invasive approach.
AnyangAges 35 years+ - NCT00341237Recruiting
Study linking genes and environment to health risks
This study looks at how your genes and your environment may affect your health. It may help researchers better understand who is most at risk so future prevention and care can be more personalized.
Chapel Hill, North CarolinaAges 18–120 - NCT02039752Recruiting
Registry for adults with multi-vessel heart disease
This study is a registry that collects information about adults with heart disease affecting more than one vessel. It may help doctors better understand how these conditions are managed over time at Asan Medical Center.
SeoulAges 19 years+ - NCT00762333Recruiting
Blood tests after a heart attack to study heart strain markers
This study looks at blood test “markers” soon after an acute heart attack, to better understand heart damage and whether heart failure is present. It may help doctors improve how they monitor recovery and risk in people after a heart attack.
Farmington, ConnecticutAges 18 years+ - NCT00483249Recruiting
Stent treatment for large abdominal aortic aneurysms
This trial studies a less invasive stent procedure that blocks blood flow into certain large aneurysms in the chest-to-abdomen or upper abdomen area. It may help prevent aneurysm growth and rupture while avoiding the risks of open surgery.
San Francisco, CaliforniaAges 18 years+ - NCT00794001Recruiting
Timing feedback to improve treatment for heart attack patients
This trial studies whether feedback about treatment timing can help people who are having a specific type of heart attack get treated faster and more effectively. You may be eligible if you arrived for emergency heart catheter treatment soon after symptoms began.
Hildesheim, Lower SaxonyAges Any age - NCT01788592Recruiting
Study of drug-coated stents in routine heart procedure care
This study follows people who need a heart procedure to open narrowed coronary arteries using a drug-coated stent. It aims to see how well these stents work and how people do in everyday clinical practice.
SeoulAges 18 years+ - NCT00932139Recruiting
Electro-acupuncture to help lower high blood pressure
This trial studies whether electro-acupuncture can improve blood pressure in people with mild coronary artery disease or high blood pressure. If it works, it may offer a non-medicine approach to better blood pressure control.
Irvine, CaliforniaAges 18–85 - NCT01186133Recruiting
Testing drug-coated stents in routine heart artery treatment
This trial looks at how different types of drug-coated stents work in everyday care for people with blocked heart arteries. It may help doctors choose the best stent type to keep the artery open after treatment.
Multiple LocationsAges 19 years+ - NCT00623389Recruiting
Testing a leg neuroprosthesis for walking and leg control
This trial tests an advanced device that helps control and use your legs and trunk muscles for movement. It may help people with certain types of paralysis or weakness to improve function, while closely monitoring safety and comfort.
Cleveland, OhioAges 21–75 - NCT01894802Recruiting
Brain recording and stimulation to help control a computer
This study tests a brain-machine interface that records brain activity and uses stimulation to help people with severe hand/arm movement loss communicate or control tasks using a computer. It may help restore some control and reduce dependence on hands that cannot be used normally.
Chicago, IllinoisAges 22–70 - NCT01372800Recruiting
Study blood adiponectin levels and stroke/heart risk
This study measures a blood marker called adiponectin and looks at how it relates to heart and stroke (cardiovascular and cerebrovascular) problems over time. It may help doctors understand who is at higher risk, especially in Chinese participants.
Xi'an, ShaanxiAges 18–85 - NCT01627301Recruiting
Study of stress-related body overactivity in people with PTSD
This study looks at how the body’s stress system works in veterans with PTSD compared with veterans without PTSD. You may be asked about blood pressure, lifestyle, and health conditions to see whether the study measures differences that could help future treatment.
Decatur, GeorgiaAges 18–65 - NCT00874783Recruiting
Testing nerve-cell growth from donated body cells
This trial uses donated body cells or small hair samples from people with neurological diseases (and healthy donors) to try to grow “nerve-like” cells for research. It may help scientists learn how to better study and treat different neurological conditions.
Jerusalem, IsraelAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,062 recruiting cardiology studies from the U.S. registry right now, out of 15,523 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.