Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07448181Recruiting
Daily tracking of hereditary angioedema burden
This study uses a smartphone app to track how hereditary angioedema affects your daily life over 8 weeks. It aims to better understand the real-world burden of the condition and may help improve care.
MilanAges 18 years+ - NCT07447934Recruiting
Vibration therapy for leg muscle stiffness
This trial tests if gentle vibrations can reduce muscle stiffness (spasticity) in the lower leg after a neurologic condition like stroke or brain injury. You may join if you've had spasticity for at least 6 months and can stand with or without help.
New York, New YorkAges 18–85 - NCT07448532Recruiting
Comparing electrical stimulation and mirror therapy for foot drop after stroke
This trial compares two treatments—electrical stimulation and mirror therapy—to help people who had a stroke within the last 6 months lift their foot better when walking. The goal is to improve foot clearance and reduce trips or falls.
Lahore, Punjab ProvinceAges 18–85 - NCT07448818Recruiting
Strength training for older adults with high blood pressure
This study tests whether different types of strength training (dynamic and isometric) can help older adults with high blood pressure who are already taking medication. It's designed for people who are not very active and have no major health risks.
São Paulo, São PauloAges 60 years+ - NCT07448779Recruiting
A study on N-glycosylation and its role in AL amyloidosis
This research study looks at how certain sugar molecules (N-glycosylation) on proteins may play a role in a disease called AL amyloidosis. Researchers will study blood samples from people with related plasma cell disorders to learn more about these sugars, which could help with diagnosis and treatment.
Pavia, PVAges 18–99 - NCT07448935Recruiting
Understanding a gene's role in AL amyloidosis and POEMS
This study looks at how a specific gene (IGLV1-44) affects two rare diseases: AL amyloidosis and POEMS syndrome. It involves a blood draw and possibly a bone marrow sample to learn more about how the gene works in these conditions.
PaviaAges 18–99 - NCT07449728Recruiting
Laser treatment for varicose veins with different wavelengths
This trial tests different types of laser energy to treat varicose veins. It looks at which wavelength works best for closing the faulty vein and preventing the disease from getting worse.
MoscowAges 18 years+ - NCT07450274Recruiting
Arm and hand rehab after a first stroke
This trial tests a rehabilitation program to improve arm and hand function after a first stroke. It is designed for people who have some movement but need extra help to recover strength and control.
RzeszówAges 45–80 - NCT07450846Recruiting
Heart-lung interaction in severe breathing problems
This study looks at how the heart and lungs interact in patients with acute respiratory distress syndrome (a severe lung condition) who are on a breathing machine. Researchers will use ultrasound to check heart function at different times during treatment.
Le Kremlin-BicêtreAges 18 years+ - NCT07451457Recruiting
Structured education program for heart failure patients
This trial tests if a structured education program helps people with heart failure manage their condition better. If you have been hospitalized for heart failure or are treated at a heart failure clinic, you may be able to join and learn more about your care.
BudapestAges 18 years+ - NCT07451522Recruiting
Comparing pain relief methods after heart bypass surgery
This study compares different ways to manage pain after coronary artery bypass grafting (CABG), which is heart bypass surgery. The goal is to find which approach works best and is safest for patients in the early recovery period.
Vladivostok, Outside USAges 18–75 - NCT07451873Recruiting
Glycocalyx and stress in blood vessel function (Part 2)
This study looks at how a protective layer inside your blood vessels (the glycocalyx) and oxidative stress affect blood vessel function after heart bypass surgery. The goal is to better understand why some people recover differently.
OsijekAges 18 years+ - NCT07452198RecruitingPhase 3
Study of new drug for relapsed or hard-to-treat multiple myeloma
This trial tests a new medicine (GR1803) against a standard combination treatment for people whose multiple myeloma has come back or stopped responding to prior therapies. It aims to see if the new drug works better.
TianjinAges 18 years+ - NCT07452276Recruiting
AI brain training for stroke recovery
This trial tests a computerized brain-training program that uses artificial intelligence to help people with memory problems after a stroke. If you are between 45 and 60 and had a stroke at least 3 months ago, you may be able to join.
Cairo, EgyptAges 45–60 - NCT07452991Recruiting
Ultrasound-guided clot-busting for moderate-risk pulmonary embolism
This trial tests a procedure that uses ultrasound to guide a catheter that delivers clot-dissolving medicine directly to a blood clot in the lungs. It is for people who have a pulmonary embolism that causes some heart strain but who are not in shock.
MoscowAges 18 years+ - NCT07453017Recruiting
Electrical impedance tomography for pulmonary hypertension
This study tests a new, noninvasive way to measure lung function in people with pulmonary hypertension (high blood pressure in the lungs). It uses a belt with electrodes placed around your chest during a standard heart catheterization procedure.
São Paulo, São PauloAges 18 years+ - NCT07453251Recruiting
Tracking aortic strength for aneurysm surgery patients
This study tracks how the thickness of the aortic wall relates to strength in people having surgery for an aortic aneurysm. It aims to better understand the condition and possibly improve future care.
San Donato Milanese, MIAges 18 years+ - NCT07453550Recruiting
Exercise and Blood Pressure Study
This study tests whether short periods of exercise can lower blood pressure. It is for adults with slightly elevated blood pressure who are not on medication and do not smoke or have certain health conditions.
West Hartford, ConnecticutAges 18–55 - NCT07454070Recruiting
Testing ear nerve stimulation for depression after a heart attack
This trial tests if a gentle, non-invasive ear stimulation device can help relieve depression in people who have had a heart attack and a stent placed. It aims to offer a drug-free option for those who choose not to take antidepressants or see a therapist.
Xi'an, ShaanxiAges 18 years+ - NCT07454317Recruiting
Biofeedback for managing paroxysmal atrial fibrillation
This trial tests whether biofeedback—a technique that helps you learn to control your body's stress responses—can help people with paroxysmal atrial fibrillation (a type of irregular heartbeat that comes and goes) manage their condition better. If you have this kind of AFib and are otherwise stable, this study may be a good fit.
Liverpool, MerseysideAges 18 years+ - NCT07454382RecruitingPhase 2
Study of elranatamab and cyclophosphamide for multiple myeloma
This trial studies a new medicine called elranatamab combined with the chemotherapy drug cyclophosphamide for people with multiple myeloma that has returned or not responded to prior treatments. It may be a good option if you have aggressive or high-risk myeloma.
Basking Ridge, New JerseyAges 18 years+ - NCT07455201Recruiting
CT scan for brain bleed removal surgery
This trial studies a new CT scan designed to help doctors guide a special minimally invasive surgery to remove a brain bleed. It's for patients who are already scheduled for this procedure at Mount Sinai West Hospital.
New York, New YorkAges 18 years+ - NCT07455292Recruiting
Heart valve study using advanced MRI
This study uses a special type of MRI, called 4D flow MRI, to better understand how severe aortic stenosis (a narrowed heart valve) affects heart function. It may help doctors learn more about different types of this condition and improve future treatment.
San Donato MilaneseAges 18 years+ - NCT07456293Recruiting
Electrical stimulation for hand recovery after stroke
This study tests whether a mild electrical stimulation (applied through sticky pads on your forearm) helps improve hand movement and function after a recent stroke. It's designed for people in the subacute recovery phase.
Cairo, Cairo GovernorateAges 9 months–1.1 years
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.