Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07393009Recruiting
Study of a new left bundle branch area pacing system
This study tests a new type of pacemaker system that delivers pacing to the left side of the heart through a lead placed deep in the wall between the lower chambers. The goal is to see if this approach works well for people who need a pacemaker or CRT.
AdelaideAges 18 years+ - NCT07298694Enrolling by invitation
Choosing a hypertension medication with helpful defaults
This trial tests whether changing the default options in doctors' ordering systems can help patients get the best medication for high blood pressure. You may be eligible if you are an adult who recently received a prescription for a common blood pressure drug at a participating clinic.
Danville, PennsylvaniaAges 18 years+ - NCT07619885RecruitingPhase 1
Testing a New Blood Thinner Called CG-0255 in Healthy People
This study tests how a new blood-thinning medication (CG-0255) works in the body and compares it with Plavix, a common blood thinner. Researchers will measure how much of the drug enters your bloodstream and what effects it has on your blood clotting ability.
Miami, FloridaAges 18–55 - NCT07643922Recruiting
Endovascular Treatment for Brain Blood Vessel Spasm After Aneurysm Rupture
This trial tests an endovascular procedure (a minimally invasive catheter-based treatment delivered through blood vessels) combined with a heart medication called milrinone to treat cerebral vasospasm—dangerous blood vessel narrowing that can occur after a ruptured brain aneurysm. The goal is to improve neurological recovery and prevent stroke.
Beijing, Beijing MunicipalityAges 18–80 - NCT05880576Enrolling by invitation
Watch study for newborns suspected of aortic arch blockage
This study uses heart ultrasound findings and related measurements to better understand blood flow in newborns with suspected blockage in the aortic arch. It may help doctors improve how they evaluate and manage coarctation of the aorta and similar heart narrowing.
Boston, MassachusettsAges birth–2 months - NCT07486791Recruiting
Baduanjin exercise for heart health after heart attack
This study tests whether a gentle exercise called 'Lying-Sitting-Standing' Baduanjin can improve heart and lung function and quality of life in people who have had a heart attack and also have heart failure.
Taiyuan, ShanxiAges Up to 85 years - NCT07487363RecruitingPhase 1/Phase 2
TB-500 for heart health in stable artery disease
This study tests if TB-500 can improve blood markers of cardiovascular health in people with stable artery disease. It is an early-phase trial to see if the drug is safe and shows promise.
Shenzhen, GuangdongAges 40–75 - NCT07487961Recruiting
Checking abdominal aorta size in women
This study measures the diameter of the abdominal aorta in women aged 50 and older using an ultrasound. It aims to understand normal sizes and identify any enlargements that may need monitoring.
MilanAges 50 years+ - NCT07488052Recruiting
Home ECG test to check heart health
This trial tests whether a simple home electrocardiogram (ECG) can be used to check your heart function. It may help find people who have a weak heart pump without needing a full heart ultrasound right away.
TaipeiAges 20–90 - NCT07488104Recruiting
Testing the LEEF-shoe for diabetic foot health
This study tests a special shoe designed to reduce foot pressure in people with diabetes and nerve damage. It looks at how well the shoe fits and how comfortable it feels to wear.
Groningen, Provincie GroningenAges 18 years+ - NCT07488247RecruitingPhase 3
Light-Activated Gel for Diabetic Foot Ulcers
This trial tests a gel containing a light-activated drug (chlorin E6) for diabetic foot ulcers. The gel is applied to the ulcer and then activated with a special light to help the wound heal. It may be a good option if you have a foot ulcer that hasn't healed in 6 weeks or more.
Karachi, SindhAges 18 years+ - NCT07489105Recruiting
Yoga for better thinking with heart failure
This trial tests if a yoga program can help improve memory and thinking in people with heart failure. It's designed for adults 55 and older who are not already doing yoga and are able to take part in gentle physical activity.
Auburn, AlabamaAges 55 years+ - NCT07489534RecruitingPhase 2
CAR-T therapy for multiple myeloma with kidney problems
This trial tests a new type of cell therapy (CAR-T cells) for people with multiple myeloma who also have kidney problems. It aims to see if this treatment can help keep the cancer in remission after initial therapy.
Beijing, Beijing MunicipalityAges 14 years+ - NCT07489547RecruitingPhase 2/Phase 3
Can stable heart failure patients stop some medications?
This trial is testing whether people whose heart failure has improved (with better pumping strength) can safely stop taking some of their heart medications. It is for stable patients who have had significant improvement in their heart function from a low point.
Porto Alegre, Rio Grande do SulAges 18 years+ - NCT07490054RecruitingPhase 1
Fecal transplant for chronic heart failure
This trial tests whether transferring healthy gut bacteria (fecal microbiota transplant) can help people with chronic heart failure feel better and improve their heart function.
New York, New YorkAges 18 years+ - NCT07490613RecruitingPhase 1
Study of SHR-3836 for people with multiple myeloma
This trial tests a new drug called SHR-3836 for patients with multiple myeloma that has come back or stopped responding to treatment. The goal is to see if the drug is safe and how it works against the cancer.
Suzhou, JiangsuAges 18 years+ - NCT07491094Recruiting
Repeat scans for monitoring pulmonary embolism
This trial is testing if repeated imaging can help monitor blood clots in the lungs (pulmonary embolism) over time. It may help doctors know how well treatment is working and if further care is needed.
Gothenburg, Region Västra GötalandAges 18 years+ - NCT07491315Recruiting
Do ME/CFS patients react differently to exercise?
This study looks at whether people with ME/CFS have a different reaction to exercise compared to people with heart conditions who also feel tired. It involves filling out online questionnaires and may help doctors better understand ME/CFS.
MarseilleAges 18 years+ - NCT07491718Recruiting
MRI with manganese for takotsubo cardiomyopathy
This study uses a special MRI with a contrast agent called manganese to look at how the heart works in people with takotsubo cardiomyopathy (broken heart syndrome). It may help doctors understand why this condition happens and how to treat it better.
EdinburghAges 18 years+ - NCT07491913Recruiting
Stopping biologic therapy for Takayasu arteritis in stable patients
This study looks at whether it is safe for people with Takayasu arteritis to stop taking their biologic medication (like TNF inhibitors or tocilizumab) if they have been in remission—meaning their disease has been quiet—for a long time. You might join this trial if your condition has been stable for years and you haven't needed steroids lately.
IstanbulAges 18 years+ - NCT07492511Recruiting
Ultrasound patterns in kidney and liver after trauma
This trial uses special ultrasound (Doppler) to look at blood flow in the kidneys and liver after a serious injury. It aims to find patterns that could help doctors better understand and treat trauma patients.
BolognaAges 18–65 - NCT07492719Recruiting
Swallowing exercises with visual feedback after stroke
This study tests whether special swallowing exercises with a visual feedback tool can help people who have trouble swallowing after a recent stroke. If you've had a stroke in the last 6 months and have trouble swallowing, this may help you regain strength.
AnkaraAges 18 years+ - NCT07493096Recruiting
Intensive therapy program for children with brain-based conditions
This trial tests an intensive therapy program designed to help children with brain-based conditions like cerebral palsy or autism improve their skills in movement, thinking, and daily activities. The program runs for 2 weeks with daily sessions, and researchers will check for changes in your child's abilities.
The Woodlands, TexasAges 4–12 - NCT07493603RecruitingPhase 1/Phase 2
Herbal medicine study for chest pain after stent placement
This trial tests a traditional Chinese herbal formula, Yiyang Huoluo Decoction, for people who still have chest discomfort after getting a stent for coronary heart disease. It aims to see if the herbal treatment can improve symptoms.
Huzhou, ZhejiangAges 50–75
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.