Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,066 recruiting studies in this area right now.
By phase
- Not applicable8,037
- Phase 2488
- Phase 4482
- Phase 3452
- Phase 1360
- Phase 1/Phase 2161
- Phase 2/Phase 386
Top conditions
- Stroke856
- Heart Failure566
- Hypertension403
- Cardiovascular Diseases390
- Coronary Artery Disease375
- Multiple Myeloma329
- Atrial Fibrillation273
- Ischemic Stroke199
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome83
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida145
- Illinois120
- Maryland120
- Texas120
- Minnesota119
Recruiting studies10,063 total
- NCT07552142Recruiting
Heart Failure Check-In: Using Questionnaires to Spot Early Warning Signs
This study asks heart failure patients who recently were hospitalized to answer regular questionnaires about how they're feeling. Researchers want to see if these questions can detect when heart failure is getting worse before a patient needs emergency care.
Moscow, Non-US/Non-CanadianAges 18 years+ - NCT07552389RecruitingPhase 3
Blood Pressure and Diabetes Combination Drug Trial
This study tests whether taking two separate blood pressure medications work as well as taking them combined in one pill for people with high blood pressure and type 2 diabetes. The goal is to find the best, safest way to treat both conditions together.
SeoulAges 19 years+ - NCT07552571Recruiting
Goal Setting and Healthy Habits for Chronic Disease
This study tests whether setting personal health goals and using a smartphone app helps people with long-term conditions like high blood pressure, diabetes, or high cholesterol stay healthier and more active. You'll participate in group activities designed to help you commit to and achieve your own health goals.
Wuhan, HubeiAges 45 years+ - NCT07552636Recruiting
Monitoring Giant Cell Arteritis During Treatment Tapering
This study tracks patients with giant cell arteritis (GCA, a blood vessel inflammation affecting older adults) who are in remission and tapering their steroid medications. Researchers will monitor disease activity through blood tests and patient questionnaires to understand if their condition stays stable as they reduce treatment.
AalborgAges 50 years+ - NCT07552610Recruiting
Sivelestat sodium added to clot removal surgery for stroke
This trial tests whether adding a medication called sivelestat sodium to emergency clot removal surgery (mechanical thrombectomy) can improve outcomes in patients with a specific type of stroke caused by a large blood clot in the front part of the brain. The goal is to see if this combination treatment leads to better recovery.
Weifang, ShandongAges 18–80 - NCT07552948Recruiting
Radial vs. Vein Grafts for Heart Bypass Surgery
This study compares two types of blood vessels used in heart bypass surgery: the radial artery (from your forearm) versus a vein (typically from your leg). Researchers want to see which graft option works better and lasts longer in women with severe heart disease.
TomskAges 18 years+ - NCT07553442RecruitingPhase 2
Testing ALN-AGT01 RVR for mild to moderate high blood pressure
This study tests a new experimental drug called ALN-AGT01 RVR in people with mild to moderate high blood pressure. The drug may help lower blood pressure by targeting a protein in the body that regulates blood pressure.
Lake Forest, CaliforniaAges 18–75 - NCT07554820RecruitingPhase 4
Heart Protection in Rheumatoid Arthritis With New Medications
This study compares two treatment approaches for people with active rheumatoid arthritis who also have heart disease risk factors. It tests whether a newer drug called tofacitinib, combined with cholesterol medication, can better protect the heart than traditional TNF-inhibitor treatments.
Lahore, Punjab ProvinceAges 50–85 - NCT07555574Recruiting
New imaging technology to see retinal structures clearly
This research study tests a new camera technology that takes detailed pictures of the back of your eye (retina) to better understand eye diseases. Researchers want to compare images from people with eye conditions like diabetes-related eye disease, glaucoma, or age-related macular degeneration with healthy volunteers to see how the new imaging works.
Melbourne, VictoriaAges 18 years+ - NCT07555652Recruiting
Cooling treatment for newborns with birth-related brain injury
This trial studies whether cooling a newborn's body after a difficult birth helps prevent brain damage. Researchers will track babies treated with this cooling therapy and use brain imaging to see how well it works.
Ha Nội, HanoiAges birth–6 hours - NCT07556068Recruiting
Brain Blood Flow Recovery After Stroke Clot Removal
This study enrolls people who had an acute ischemic stroke (caused by a blood clot) and received emergency treatment to remove the clot. Researchers want to understand why some patients recover well while others don't, by measuring how the brain regulates its own blood flow after treatment.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07556133Recruiting
Comparing two sedation medicines during cataract surgery
This study tests two sedation medicines (dexmedetomidine and propofol) used to keep patients calm and comfortable during cataract surgery. Researchers want to see which combination works best and is safest for this common procedure.
BeirutAges 18 years+ - NCT07556185Recruiting
Testing a home heart health monitoring app for kids
This study tests whether young people with heart conditions can use a home monitoring app called Medly to track their symptoms and weight. The app may help doctors catch problems earlier and keep kids healthier at home.
Toronto, OntarioAges 8–18 - NCT07556523RecruitingPhase 4
Recovery quality after heart valve replacement with different sedation
This study compares how well patients recover after a minimally invasive heart valve procedure (TAVR) when given different types of sedation. The goal is to find which sedation approach helps patients feel better and recover faster after the procedure.
Glenview, IllinoisAges 18–90 - NCT07556887Recruiting
Using IMPROVE to Choose Carotid Artery Treatment After Stroke
This study tests whether a new tool called IMPROVE helps doctors decide if you need surgery or a stent to clear a narrowed carotid artery (a major neck blood vessel) after a recent stroke or mini-stroke. The goal is to better predict which patients will benefit most from this treatment.
Arnhem, GelderlandAges 18 years+ - NCT07556991RecruitingPhase 2/Phase 3
Infection's Role in Chronic Brain Bleeding
This study investigates whether infection contributes to chronic subdural hematoma, a condition where blood collects between the brain and skull. Researchers will study patients undergoing surgery to understand infection's involvement and potentially improve treatment.
RostockAges 18 years+ - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07557225Recruiting
New PET Scan for Detecting Multiple Cancer Types
This study tests a new type of PET scan (a specialized imaging test) that may better detect certain cancers by looking for a specific marker found on many tumor types. The scan uses a new tracer called 18F-T2 to help doctors see cancer more clearly.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07557498Recruiting
Mavacamten Outcomes and Experiences in Heart Muscle Disease
This study looks at how mavacamten (a heart medication) works for people with obstructive hypertrophic cardiomyopathy (HCM)—a condition where heart muscle becomes too thick. Researchers will review medical records and ask patients about their experiences with the treatment.
Bollington, MacclesfieldAges 18 years+ - NCT07558109Recruiting
Digital Heart Ultrasound Study
This study tests a new digital method for analyzing heart ultrasound images. Researchers want to see if computer software can help doctors read heart scans more accurately and quickly.
Hong KongAges 18 years+ - NCT07558382Recruiting
Global registry for Takayasu arteritis patients
This study collects medical information from patients diagnosed with Takayasu arteritis, a rare disease affecting large blood vessels. By joining, you help researchers better understand this condition and improve care for future patients.
Istanbul, IstanbulAges Any age - NCT07558876Recruiting
Upper limb training with vibration therapy after stroke
This trial tests whether combining task-oriented exercises with focal vibration (gentle vibrating stimulation) can help improve arm and hand function and feeling in people who've had a stroke. The vibration aims to help your brain better sense where your hand is and what it's touching.
SeoulAges 20 years+ - NCT07558915RecruitingPhase 1
Testing RO7851624 for Relapsed Multiple Myeloma
This Phase 1 trial tests a new drug called RO7851624 in patients whose multiple myeloma has come back or stopped responding to prior treatments. The goal is to understand how safe and effective this drug is.
Parkville, VictoriaAges 18 years+ - NCT07559253Recruiting
Heart Care Transition Education Led by Nurses or Doctors
This study tests whether nurse-led or doctor-led education helps young people with congenital heart disease (a heart condition present from birth) transition from pediatric to adult care. The goal is to make this transition smoother and more accessible for all patients, including those with disabilities.
Madison, WisconsinAges 12–26
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,066 recruiting cardiology studies from the U.S. registry right now, out of 15,554 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.