Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT04667078RecruitingPhase 3
Cangrelor plus thrombectomy to improve blood flow imaging in stroke
This Phase 3 trial tests whether adding a clot-fighting medicine called cangrelor to a mechanical clot-removal procedure (thrombectomy) can improve outcomes in selected acute stroke patients. It targets people whose scan shows there may be salvageable brain tissue, aiming to protect more brain while the clot is treated.
BesançonAges 18–80 - NCT04075162Recruiting
Free heart calcium scan program at University Hospitals
This study is looking at people who already received a free coronary artery calcium (CAC) CT scan through a community screening program at University Hospitals. It may help the hospital understand who benefits from offering these no-cost scans.
Cleveland, OhioAges 18–100 - NCT04343443Recruiting
Test whether a lung ultrasound helps discharge planning after heart failure
This study looks at people hospitalized for worsening heart failure with weaker pumping (reduced ejection fraction). It tests whether a lung ultrasound evaluation near discharge can improve how doctors decide it is safe to send you home.
Vandœuvre-lès-NancyAges 18 years+ - NCT04101188Recruiting
Study how extra potassium affects blood vessels
This study looks at how eating more potassium may protect blood vessels in healthy people. You may be eligible if you have normal blood pressure and a normal heart rhythm test, and you do not have certain health conditions.
Newark, DelawareAges 18–45 - NCT04934748Enrolling by invitationPhase 4
Blood pressure medication study during major non-heart surgery
This trial tests how doctors manage blood pressure during major surgery using common medicines (norepinephrine or phenylephrine). It may help by improving safety for people at higher risk of blood pressure drops or complications during surgery.
Omaha, NebraskaAges 45 years+ - NCT04212520Recruiting
Using non-fasting cholesterol tests to predict heart events
This study looks at whether cholesterol levels measured without fasting can help predict future heart and blood vessel events in people living in the community. If you join, your non-fasting blood test results may be tracked to see how well they forecast cardiovascular risk.
Guangzhou, GuangdongAges 18 years+ - NCT03999138Recruiting
MRI study of lung fluid changes in acute heart failure
This study uses MRI scans to measure lung fluid (pulmonary edema) in people hospitalized for acute heart failure. It aims to see how well the lung fluid responds to standard treatments like water pills (diuretics) given in the first couple of days.
Edmonton, AlbertaAges 18 years+ - NCT04050956Recruiting
Study of heart attack patients soon after symptoms begin
This study follows people who have had a heart attack very recently (within 48 hours) to evaluate care and outcomes. You may be invited if your diagnosis fits a typical heart-attack pattern and you can consent.
ParisAges 18 years+ - NCT04137549Recruiting
Monitoring nighttime blood pressure to reach target levels
This registry study looks at how well people can control high blood pressure during sleep. It may help your care team understand what changes support safer nighttime blood pressure targets.
Shanghai, Shanghai MunicipalityAges 50–79 - NCT04113356Recruiting
MRI study after first heart attack treated with fast angioplasty
This trial tests how well a heart MRI can be used soon after a first heart attack, especially when a blocked artery is opened quickly with angioplasty. It may help doctors better assess heart injury and guide care after an emergency heart event.
InnsbruckAges 18 years+ - NCT04257747Recruiting
3T MRI study of hand and forearm blood flow
This study uses a powerful MRI scanner (3 Tesla) to measure blood flow in the arteries of the hand and forearm under normal and certain medical conditions. You may qualify if you’re an adult and can safely have an MRI, either as a healthy volunteer or someone needing specific hand/arm surgery.
AmiensAges 18 years+ - NCT04329234Recruiting
Heart failure registry study of hospitalized adults
This study collects information from adults hospitalized with heart failure to better understand the condition and outcomes. It may help doctors improve care over time by tracking symptoms, test results, and treatments.
SeongnamAges 18 years+ - NCT04092192Recruiting
Removing an IVC filter: forceps versus snare tools
This trial compares two different tools for taking out an IVC filter (a device placed in a large vein to help prevent blood clots). It’s meant to find which removal method is safer and works better for eligible adults who just had a specific filter placed.
Chicago, IllinoisAges 18 years+ - NCT04600115RecruitingEarly Phase 1
New MRI methods for heart failure with preserved pumping function
This study tests advanced MRI techniques to better understand heart failure with preserved ejection fraction (HFpEF), a condition where the heart pumps normally but still doesn't work well. It may help improve diagnosis and treatment for patients with this type of heart failure.
Salt Lake City, UtahAges 18 years+ - NCT04449523Recruiting
Check for hidden heart rhythm problems after silent brain strokes
This study looks at how often “silent” atrial fibrillation—an irregular heart rhythm that can be symptom-free—happens in people who have silent brain stroke spots on MRI. If it finds a link, it may help identify which patients might benefit from closer heart monitoring or prevention steps.
GrazAges 50 years+ - NCT04331249Recruiting
Monitoring heart device during and around your procedure
This trial looks at how to manage and check implanted heart devices (pacemakers/defibrillators) during and around a planned procedure. It may help teams improve safety and decision-making during surgery or catheter procedures.
Fürth, BavariaAges 18 years+ - NCT04066127Enrolling by invitation
Heart transplant study comparing two types of heart storage
This trial tests whether using a different method to store a donated heart before transplant improves outcomes. It compares “non-ischemic preservation” versus standard cold storage for people getting a new heart.
Lund, Skåne CountyAges 18 years+ - NCT04226612Recruiting
Link between inpatient blood pressure and in-hospital complications
This study looks at whether higher or lower blood pressure during a hospital stay is associated with complications during the same stay. It may help doctors better identify risk and improve monitoring.
Guangzhou, GuangdongAges Any age - NCT06825936Recruiting
Asian-Mediterranean diet for women's health
This trial tests whether an Asian-Mediterranean diet helps improve health in women who are overweight or obese. You would follow a special eating plan for six months and learn how it affects your weight, heart, and overall well-being.
Singapore, SingaporeAges 21–50 - NCT02888353Enrolling by invitation
MRI safety check for people with pacemakers or defibrillators
This trial studies whether it’s safe to do MRI scans in people who already have a pacemaker or an implanted defibrillator (ICD) when they medically need an MRI. It’s for patients who can pass the usual MRI safety screening.
Baltimore, MarylandAges 9–100 - NCT03513770RecruitingEarly Phase 1
Testing how the body controls blood pressure and heart rate
This early research trial looks at how your body’s automatic control system manages blood pressure and heart function. You may be asked to undergo tests to measure these responses, and the study aims to understand control of the circulation (blood flow).
Hershey, PennsylvaniaAges 21–35 - NCT02901184RecruitingPhase 3
Spironolactone start study for heart failure with preserved pumping
This trial tests whether starting spironolactone helps people with heart failure symptoms when the heart pumps “preserved” (not severely reduced). Participants are assigned to start spironolactone or usual care so researchers can see if it improves outcomes.
Alexander City, AlabamaAges 50–99 - NCT03746964Recruiting
MRI study of the heart’s aorta before planned surgery
This study uses a special MRI scan to measure how the ascending aorta (a large blood vessel) moves and behaves before planned surgery. It may help doctors better understand the mechanics of an aortic aneurysm and improve future surgical planning.
DijonAges 18 years+ - NCT02016430Recruiting
Diet study to lower TMAO levels using gut microbes
This trial looks at whether a structured 12-week diet can lower a blood chemical called TMAO, which is linked to heart and kidney risk for some people. It may help you see if diet changes can shift gut microbes and reduce TMAO-related signals.
Cleveland, OhioAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.