Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT04005508Recruiting
Study sleep apnea and heart outcomes in high-risk atrial fibrillation
This trial looks at how obstructive sleep apnea (OSA, a breathing problem during sleep) relates to heart outcomes in people with atrial fibrillation (AF). It may help doctors better predict risk and choose safer care for people who are high cardiovascular risk.
SingaporeAges 22–99 - NCT06420479Recruiting
How weight-loss surgery affects heart disease risk
This study looks at how weight-loss surgery (bariatric surgery) affects the chances of developing heart disease or dying early. It may help you if you have obesity but have never had heart problems or cancer before.
StockholmAges 18 years+ - NCT06407947RecruitingEarly Phase 1
CT071 for high-risk newly diagnosed multiple myeloma
This trial tests an experimental therapy called CT071 for people with newly diagnosed, high-risk multiple myeloma. It aims to see if this treatment can help control the disease in people who have certain aggressive features.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT04240834RecruitingPhase 4
Low-dose ticagrelor vs aspirin after heart stent placement
This study compares ticagrelor taken at a lower dose versus regular aspirin to help prevent future heart attacks in people who recently had a stent placed after acute coronary syndrome. You may qualify if you’re considered “high risk” for new blockages or clots and can take dual anti-platelet therapy for 12 months.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06455644Recruiting
CT vs. X-ray for sizing heart device in AF treatment
This study tests whether using a CT scan or a special X-ray (DSA) is better for picking the right size of a left atrial appendage closure device during a combined ablation and closure procedure. It aims to make the procedure safer and more effective.
Foshan, GuangdongAges 18 years+ - NCT06455488Recruiting
Ventricular tachycardia management outcomes registry
This registry collects information about how ventricular tachycardia (a fast heart rhythm from the lower chambers) is managed and the results of different treatments. Participating can help improve future care.
Chicago, IllinoisAges 18 years+ - NCT06021808Recruiting
LAA clip vs. blood thinners to prevent stroke in non-paroxysmal AF
This study compares two ways to prevent stroke in people with persistent or long-standing atrial fibrillation (AF): taking a blood thinner (NOAC) or having a minimally invasive procedure to clip off the left atrial appendage (LAA). The goal is to see which approach works better at preventing stroke without causing major bleeding.
Beijing, Beijing MunicipalityAges 18 years+ - NCT04615065Recruiting
Biobank study collecting emergency data for very sick patients
This study collects health and sometimes blood sample information from people arriving at the emergency department with high-risk or serious conditions. The goal is to build a large emergency “biobank” to help researchers better understand and improve urgent care.
GroningenAges 18 years+ - NCT05969028Recruiting
Testing breathing and chest compression timing for out-of-hospital cardiac arrest
This trial studies the best timing for chest compressions and airway management for adults who have sudden cardiac arrest outside the hospital. It may help improve survival chances by guiding first EMS responders on how to act sooner and more consistently.
Seattle, WashingtonAges 18 years+ - NCT06456814Recruiting
Study on how brain aneurysms form, grow, and rupture
This study looks at medical records from multiple hospitals in China to understand how brain aneurysms develop and when they might rupture. It may help researchers find better ways to predict and treat them.
GuangzhouAges 18–80 - NCT06444321Recruiting
Integrated care for frail patients with heart failure
This trial tests a special care program for people with both frailty (being weak or vulnerable) and heart failure (when the heart doesn't pump well). The program brings together different types of support to help you manage your health better after a hospital stay.
Drammen, AkershusAges 18 years+ - NCT07835126Enrolling by invitation
A safer way to treat paroxysrial atrial fibrillation
This study tests a new method of catheter ablation for paroxysmal atrial fibrillation, using a special saline solution and higher power for shorter duration to isolate the pulmonary veins. It aims to improve safety and effectiveness while minimizing damage to surrounding tissue.
Ningbo, ZhejiangAges 18 years+ - NCT07834333Recruiting
Brain stimulation to help arm and leg recovery after stroke
This trial tests a non-invasive brain stimulation technique called theta burst stimulation to see if it can improve arm and leg function in people who recently had a stroke. It may help with movement recovery in the first few months after stroke.
Ankara, YenimahalleAges 45 years+ - NCT07835178Recruiting
High-pressure cutting balloon for hardened heart artery blockages
This study tests a special balloon that can cut through hardened calcium in heart arteries before placing a stent. It may help people with severe artery calcification get a better stent placement.
Xi'an, ShaanxiAges 18 years+ - NCT07838220RecruitingPhase 1
Study of IBI3016 in Japanese adults with high blood pressure
This trial tests an experimental drug called IBI3016 for lowering high blood pressure. It is specifically for Japanese adults who have high blood pressure while currently on treatment.
OsakaAges 18–75 - NCT02156401Recruiting
Study of tests and care to improve clot diagnosis
This study follows adults who may have a blood clot in the lung (pulmonary embolism) or leg (deep vein thrombosis), or who were found to have a clot by chance. It aims to improve how doctors diagnose, manage, and estimate risk, which may lead to better, more tailored care for you.
Mainz, Rhineland-PalatinateAges 18 years+ - NCT07839741RecruitingPhase 4
Lowering cholesterol with ezetimibe
This trial looks at how well ezetimibe, a medicine that lowers cholesterol, works when taken alone or alongside other cholesterol medicines. It may help people who need extra help lowering their LDL (bad) cholesterol.
PortoAges 18–75 - NCT07833995Recruiting
Long-term outcomes after heart attack and stenting
This study looks at what happens to people after they have a heart attack and receive a stent (a small mesh tube) to open the blocked heart artery. It will track their health over time to better understand the short- and long-term risks of heart and brain events like another heart attack or stroke, so doctors can improve care.
ShanghaiAges 18 years+ - NCT07842341Recruiting
Support for blood pressure and medications during pregnancy
This study checks in on you during your pregnancy and after birth to see how you're doing with your blood pressure and medications. It uses your smartphone and at-home blood pressure monitoring to help keep you and your baby healthy.
Houston, TexasAges 18–45 - NCT07840365RecruitingPhase 3
Finding the best blood-thinner plan after a Watchman device procedure
This study tests which blood-thinner approach works best after a procedure to close a small heart pouch (left atrial appendage) with a Watchman device. It aims to prevent strokes while reducing bleeding risks.
Austin, TexasAges 18 years+ - NCT07835386Recruiting
Better heart health through digital education for all ages
This study tests a digital health education program to help people from different backgrounds improve their cardiovascular health. It's open to almost anyone aged 12 to 79, whether they're healthy or have stable medical conditions.
CórdobaAges 12–80 - NCT07837934RecruitingPhase 2
Colchicine to prevent heart disease in adults with type 2 diabetes
This trial tests whether a daily low-dose of colchicine, a common anti-inflammatory medicine, can help prevent heart attacks and strokes in people with type 2 diabetes who do not yet have heart disease. If it works, it could be a simple addition to your current diabetes care.
Singapore, SingaporeAges 21–80 - NCT07837830RecruitingEarly Phase 1
Early treatment for exercise-related lung pressure
This trial tests an inhaled medicine that may help people with lung scarring or connective tissue disease who have high blood pressure in the lungs only during exercise. It aims to improve their ability to be active and reduce symptoms.
Paramus, New JerseyAges 18 years+ - NCT07837076Recruiting
Blood vessel health in healthy women over 50
This study looks at how blood vessel walls work in healthy women over 50. It may help researchers understand normal aging and guide future heart health advice.
Clermont-FerrandAges 50 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.