Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT06812767Enrolling by invitation
Chronic disease risks in working-age people
This study looks at risk factors for chronic diseases in healthy working-age adults. You may help researchers understand how to prevent conditions like heart disease or diabetes.
MoscowAges 18 years+ - NCT06808321Enrolling by invitation
Benidipine for high blood pressure or chest pain
This study looks at how well Benidipine works for people with high blood pressure or stable chest pain from heart disease. If you are already taking Benidipine for at least a month, this trial may help doctors learn more about its benefits.
AntalyaAges 18–80 - NCT06802965Enrolling by invitation
Shanghai atrial fibrillation patient registry study
This study tracks people in Shanghai who have been diagnosed with atrial fibrillation (AF, a heart rhythm condition). By joining a registry, researchers can learn more about how AF is managed over time in the local population.
ShanghaiAges Any age - NCT06801886Enrolling by invitationPhase 3
Silymarin for better kidney transplant success
This trial tests if adding silymarin (a milk thistle extract) to standard anti-rejection medicines helps protect the new kidney from damage. It may improve how well the transplanted kidney works over time.
MartinAges Any age - NCT06795763Enrolling by invitation
New imaging & catheter system for blocked heart arteries
This trial tests a new imaging and catheter system to treat chronic total blockages in heart arteries. If you still have chest pain or other symptoms despite medical therapy, this study may help open the blockage and improve blood flow.
Atlanta, GeorgiaAges 18 years+ - NCT06790173Enrolling by invitation
Strategy training for physical activity after stroke
This trial tests a strategy training program to help people with memory and thinking problems after a stroke become more physically active. If you've had a stroke in the last three years and have some trouble with focus or planning, this program may help you build skills to move more and feel better.
New Taipei CityAges 18–80 - NCT06789588Enrolling by invitationPhase 3
Better warfarin therapy for atrial fibrillation
This study tests a better way to manage warfarin (a blood thinner) for people with atrial fibrillation (an irregular heartbeat). The goal is to improve treatment and help prevent stroke.
Recife, PernambucoAges 18 years+ - NCT06787508Enrolling by invitation
Brain stimulation for speech recovery after stroke
This study tests whether repeated sessions of transcranial magnetic stimulation (a non-invasive brain stimulation therapy) can help people who recently had a stroke and are having trouble speaking (aphasia). It is for patients who were hospitalized within the last 7 days and are right-handed.
Chongqing, Municipality Directly Under the Central GovernmentAges 18 years+ - NCT06786754Enrolling by invitation
Skin cell study for Marfan syndrome and aortic aneurysms
This study looks at skin cells (fibroblasts) from people with Marfan syndrome or other genetic conditions that cause thoracic aortic aneurysms. The goal is to understand how these cells behave, which may help improve future treatments.
San Donato Milanese, MilanAges 18 years+ - NCT06786546Enrolling by invitation
Type 1 Diabetes and Blood Vessel Health Study
This study looks at how blood vessels and nerves work in people with Type 1 diabetes compared to healthy volunteers. It may help explain how diabetes affects heart and blood vessel health.
Austin, TexasAges 18–70 - NCT06781385Enrolling by invitationPhase 2
Tenecteplase after clot removal for severe stroke
This trial tests if giving a clot-busting drug (tenecteplase) directly into the brain artery after a successful clot-removal procedure can improve outcomes for people with a major stroke. It is for patients who had a large vessel blockage and received endovascular thrombectomy within 24 hours of symptoms starting.
Charlotte, North CarolinaAges 18 years+ - NCT06778356Enrolling by invitation
How environment affects your nervous system
This study looks at how things in your surroundings might change how your brain and nerves work. It could help us understand the environment's role in nervous system health.
Tampa, FloridaAges 18 years+ - NCT06777654Enrolling by invitation
Robotic therapy with mirror therapy for stroke recovery
This study tests if combining robotic therapy with mirror therapy can help improve arm function after a stroke. It is for people who had their first stroke 3 months to 2 years ago and have some but not full arm movement.
TaipeiAges 30–80 - NCT06776822Enrolling by invitation
DNS therapy for asymmetry after heart surgery in children
This trial tests whether a special physical therapy called DNS (Dynamic Neuromuscular Stabilization) can help children aged 6 to 18 who have body asymmetry (uneven movement or posture) after surgery for a congenital heart defect. Participation may improve their balance and muscle control.
PragueAges 6–18 - NCT06772207Enrolling by invitation
Heart rehab needs in atrial fibrillation patients
This study looks at what heart rehabilitation people with newly diagnosed atrial fibrillation need and how to improve their care. If you were diagnosed with atrial fibrillation in 2022 or 2023 and live in Denmark, you may be eligible.
OdenseAges 18 years+ - NCT06763783Enrolling by invitationPhase 4
Shingles vaccine study for people with rheumatic diseases
This study offers the Shingrix shingles vaccine for free to adults with inflammatory rheumatic diseases. It compares how well the vaccine works in people taking immune-suppressing drugs versus those not taking them.
LundAges 18 years+ - NCT06763549Enrolling by invitation
AI-powered wearable patch for heart and lung monitoring
This study tests an AI-powered wearable patch (the COR ECG) to see if it can better track heart and lung health. It may help doctors find problems earlier without needing bulky equipment.
Melbourne, FloridaAges 18 years+ - NCT06753227Enrolling by invitation
Comparing ways to measure valve pressure after TAVI
This trial looks at how well a new method (using echo) compares to the standard invasive method for measuring pressure across the new valve after TAVI. It may help doctors monitor your valve function with less risk.
Munich, BavariaAges 18 years+ - NCT06749145Enrolling by invitation
Using deep learning to find aortic stenosis earlier
This study tests if a deep learning tool can help detect aortic stenosis, a heart valve condition, in older adults during routine primary care visits. If you are 70 or older and have not had a recent echocardiogram, you may be able to join.
New Haven, ConnecticutAges 70 years+ - NCT06749132Enrolling by invitation
AI-powered monitoring for mild aortic valve disease
This study uses an artificial intelligence (AI) program to analyze past heart ultrasound images and predict if your aortic valve condition (mild thickening or narrowing) may get worse over time. The goal is to catch changes early and personalize your follow-up care.
New Haven, ConnecticutAges 65 years+ - NCT06748014Enrolling by invitationEarly Phase 1
Study of aescin plus MPFF for bleeding hemorrhoids
This study tests whether a combination of two medicines (aescin and MPFF) can stop bleeding from mild internal hemorrhoids (grade 1 or 2) and prevent it from coming back. If you have had active bleeding within the past 7 days, this trial may help you find an effective non-surgical treatment.
Chiang Mai, MaungAges 20 years+ - NCT06747546Enrolling by invitation
Oxygen-based blood flow management after heart surgery
This study is testing a new way to manage blood flow after heart surgery in children with congenital heart disease. The goal is to make sure the body gets the right amount of oxygen to help recovery.
Minhang, Shanghai MunicipalityAges 1 week–18 years - NCT06747013Enrolling by invitation
Focused pulse field ablation for ventricular tachycardia
This trial tests a new way to treat rapid heartbeats from the lower chambers (ventricles) using a special catheter that delivers short electrical pulses to stop the abnormal signals. It may help people with extra beats (PVCs) or a fast heart rhythm (ventricular tachycardia) that needs treatment.
New York, New YorkAges 18 years+ - NCT06725797Enrolling by invitation
Study of sulfur water for wound cleaning
This trial tests whether a special type of sulfur water can help clean and heal wounds, including infected or hard-to-treat wounds. It may be an option for people with various health conditions and wound types.
Bagni di Tivoli, RomeAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.