Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 10,073 recruiting studies in this area right now.
By phase
- Not applicable8,041
- Phase 2490
- Phase 4483
- Phase 3452
- Phase 1359
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke855
- Heart Failure565
- Hypertension403
- Cardiovascular Diseases389
- Coronary Artery Disease375
- Multiple Myeloma330
- Atrial Fibrillation273
- Ischemic Stroke200
- Atrial Fibrillation (AF)146
- Acute Ischemic Stroke141
- Pulmonary Hypertension104
- Myocardial Infarction98
- Congenital Heart Disease87
- Peripheral Arterial Disease85
- Stroke, Ischemic84
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis78
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris92
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital54
- Massachusetts General Hospital51
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Insel Gruppe AG, University Hospital Bern50
- Johns Hopkins University47
Where studies are running
- California467
- Alabama198
- Massachusetts181
- Arizona176
- New York166
- Florida146
- Maryland120
- Texas120
- Illinois119
- Minnesota119
Recruiting studies10,070 total
- NCT06429007Enrolling by invitationPhase 1
Metformin for infants after brain injury from HIE
This trial tests whether metformin, a common diabetes medicine, can help heal brain injury in infants who had HIE (lack of oxygen at birth) and were treated with cooling. It aims to see if the drug is safe and possible to give to babies between 3 and 6 months old.
Boston, MassachusettsAges 3 months–6 months - NCT06421961Enrolling by invitation
AI smartphone app for monitoring leg ulcers in PAD
This study tests a smartphone-based tool that uses artificial intelligence to help monitor hard-to-heal leg ulcers caused by poor arterial blood flow. The goal is to see if the tool can accurately assess wound healing at home.
GothenburgAges 18 years+ - NCT06421532Enrolling by invitationPhase 2
Testing LXB to clear protein buildup in CAA
This study tests whether the drug LXB (sodium oxybate) can help clear abnormal protein buildup in the brain's small blood vessels (CAA). Participants will take LXB nightly for 8 weeks and have MRIs and spinal taps to measure changes.
LeidenAges 30 years+ - NCT06412432Enrolling by invitation
Exercise and rehab for heart amyloidosis
This study tests whether a supervised exercise and rehabilitation program can help people with a specific type of heart amyloidosis (ATTRwt) feel better and improve their heart function. It may be a good fit if you have stable heart failure and can safely exercise.
NaplesAges 18 years+ - NCT06403423Enrolling by invitation
Screening for aortic aneurysms in Inland Norway
This trial invites all men in Inland Norway to get screened for aortic aneurysms, a bulge in the main artery that can be dangerous if not found early. The screening is a simple, painless ultrasound to check for this condition.
Hamar, HamarAges 65–65 - NCT06399367Enrolling by invitation
New imaging for leg swelling conditions
This study uses a special imaging machine (MSOT) to look at different types of swelling in the legs, such as lipedema and lymphedema. It aims to help doctors better understand and tell these conditions apart.
Göttingen, Lower SaxonyAges 18–80 - NCT06398366Enrolling by invitation
Heart tests to prevent another stroke
This study looks at how heart problems might cause strokes. If you had a stroke that doctors can't explain after many tests, this trial will do extra heart monitoring to find possible causes and help prevent another stroke.
Camden, New JerseyAges 18 years+ - NCT06384183Enrolling by invitation
Real-world fish skin graft registry study
This study tracks how well a fish skin graft (Kerecis) heals wounds in real patients. It helps doctors learn more about who benefits most from this treatment.
Sarasota, FloridaAges Any age - NCT06375993Enrolling by invitationPhase 1
Prula-cel for autoimmune diseases: a phase 1 study
This trial tests a new treatment called prulacabtagene leucel (prula-cel), which is a type of immune cell therapy (CAR T-cells) for people with certain autoimmune diseases. It aims to see if it can reset the immune system and reduce disease activity in conditions like lupus, scleroderma, vasculitis, or myositis.
Redwood City, CaliforniaAges 18–80 - NCT06370702Enrolling by invitation
Can hand grip exercises prevent blood clots from PICC lines?
This study tests if simple hand grip exercises can help prevent blood clots in the arm for people who just got a PICC line. If you are at least 18 and can do the exercises, you may be able to join.
Cincinnati, OhioAges 18 years+ - NCT06364293Enrolling by invitation
Predicting outcomes after aneurysm treatment
This study looks at people who have had a brain aneurysm treated with a minimally invasive procedure. Researchers want to see if they can predict who might have a worse outcome later, using follow-up images.
BeijingAges 18–80 - NCT06361524Enrolling by invitation
Gut bacteria study in chronic heart failure
This study looks at the bacteria in your gut (your 'gut microbiome') and how it relates to chronic heart failure. It may help doctors understand why some people with heart failure do better than others and could lead to better treatments in the future.
Stanford, CaliforniaAges 18–75 - NCT06350331Enrolling by invitation
Smarter blood clot care with phone/tablet help
This study tests if using a smartphone app or tablet helps doctors and patients work together to prevent or manage blood clots in the legs or lungs. It is for adults in the hospital who have or are at high risk of a blood clot.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06342999Enrolling by invitation
Fetal heart valve procedure for underdeveloped left heart
This trial tests a procedure called fetal aortic valvuloplasty (opening the baby's heart valve while still in the womb) to help the left side of the heart grow better. It's for pregnant women whose babies have a narrow aortic valve and signs that the left heart may not develop fully.
Rochester, MinnesotaAges Up to 45 years - NCT06334666Enrolling by invitation
Step counting for fatty liver disease management
This trial tests if using a pedometer to track daily steps can help people with a type of fatty liver disease (called MASLD) become more active and improve their health. It may be a good fit if you are not already very active and want to try a simple way to manage your condition.
Bangkoknoi, BangkokAges 18 years+ - NCT06332131Enrolling by invitation
Heart blood vessel effects of immunotherapy in breast and lung cancer
This trial studies whether immunotherapy drugs (called immune checkpoint inhibitors) affect the small blood vessels of the heart. If you have breast cancer or lung cancer and are starting a specific treatment plan, you may be asked to have a special heart scan before and during therapy.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06330480Enrolling by invitation
Screening for heart rhythm and kidney disease at home
This study is testing whether screening people at home can catch early signs of an irregular heartbeat (atrial fibrillation) and kidney disease. If you're in the right age group and live in one of the selected regions, you could join and help researchers learn more about spotting these conditions early.
AmsterdamAges 50–75 - NCT06328010Enrolling by invitation
Real-world data registry for wound care treatments
This study collects information on various wound types and how they respond to standard care. It aims to learn what works best for wounds that haven't healed after 4 weeks of treatment.
Scottsdale, ArizonaAges 18 years+ - NCT06320782Enrolling by invitation
Diet and belly fat study for overweight adults
This study tests how different diets affect belly fat, thigh muscle, and heart health in people who are overweight. It might help you find a way to eat that improves your health.
Recife, PernambucoAges 20 years+ - NCT06315023Enrolling by invitation
A registry study for the DETOUR system
This study is collecting information from people who receive the DETOUR system, a treatment for blocked arteries. The goal is to see how well it works in real-world use.
Salinas, CaliforniaAges Any age - NCT06299176Enrolling by invitationPhase 1
Whole-heart radiation therapy for advanced heart failure
This trial tests if a low dose of radiation to the whole heart can help people with very advanced heart failure. It is for people who have severe symptoms despite maximum medications and are not candidates for a heart pump or transplant.
Montreal, QuebecAges 65 years+ - NCT06294964Enrolling by invitation
Sleep and heart health study for older adults
This study looks at how sleep patterns affect the risk of heart disease and stroke in older adults. It aims to help improve heart health through better sleep.
ShanghaiAges 60–120 - NCT06293924Enrolling by invitation
Testing fluid around the heart in recurring pericarditis
This study analyzes pericardial fluid (the fluid around your heart) to understand why pericarditis comes back. If you have pericarditis or other heart fluid buildup requiring drainage, or if you're having heart surgery, you may be able to participate.
Milan, LombardyAges 18 years+ - NCT06275984Enrolling by invitation
Online CPR training for volunteers in Camp de Tarragona
This trial tests an online training program to teach everyday people how to perform CPR. It wants to see if a network of volunteers can be trained effectively through the internet, so you can help save lives in your community.
Barcelona, BarcelonaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 10,073 recruiting cardiology studies from the U.S. registry right now, out of 15,588 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.