Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,609 recruiting studies in this area right now.
By phase
- Not applicable7,632
- Phase 4472
- Phase 2469
- Phase 3439
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke797
- Heart Failure534
- Hypertension388
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction97
- Congenital Heart Disease84
- Peripheral Arterial Disease79
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California453
- Alabama196
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois112
Recruiting studies9,609 total
- NCT07780500Recruiting
Using electronic health records to study people with high blood pressure
This study is not testing a new medicine. Instead, it is using electronic health records to better understand people with high blood pressure, with a focus on those recently diagnosed. If you join, you may help researchers learn more about how to improve care for others with high blood pressure.
Oakland, CaliforniaAges 18 years+ - NCT07776873RecruitingPhase 3
Clot-busting medicine for stroke symptoms 4.5 to 24 hours
This study tests a clot-busting medicine given through an IV to people who had a stroke caused by a blocked medium-sized blood vessel in the brain, and who can be treated 4.5 to 24 hours after symptoms start. The goal is to see if it improves recovery and reduces disability compared to standard care.
Hefei, AnhuiAges 18 years+ - NCT07781579Recruiting
MRI study to predict bleeding risk in moyamoya disease
This study uses advanced MRI scans to better predict the risk of bleeding in people with moyamoya disease, a rare condition where brain arteries narrow. It aims to improve prevention of bleeding strokes.
Beijing, Beijing MunicipalityAges Any age - NCT04619277Recruiting
Drug-coated balloon for a new coronary artery blockage
This trial studies whether a drug-coated balloon can treat a brand-new (de novo) blockage in the coronary arteries. If you may qualify, it could offer a way to reduce problems from this blockage using a device that delivers medicine during treatment.
UlsanAges Any age - NCT06555237RecruitingPhase 2
MEK inhibitors for heart thickening in RASopathies
This trial tests a targeted drug (MEK inhibitor) to treat thickened heart muscle caused by a group of genetic conditions called RASopathies. It may help improve heart function in people with hypertrophic cardiomyopathy.
WarsawAges 1 day–18 years - NCT02098252Recruiting
Study for treating brain blood vessel malformations (AVMs)
This study is looking at treatment options for people who have an abnormal cluster of blood vessels in the brain (an AVM). It may help participants by offering a structured treatment approach, depending on the AVM type and recent symptoms.
Jacksonville, FloridaAges 5 years+ - NCT06553339RecruitingPhase 1
A study of HS-10516 for VHL syndrome tumors
This trial tests a new drug called HS-10516 in people with VHL syndrome or advanced kidney cancer. The goal is to see if the drug can shrink tumors and what side effects it might have.
Beijing, Beijing MunicipalityAges 18–80 - NCT06554925Recruiting
Sex differences in cardiac surgery patients
This study looks at how men and women may differ in their experiences and outcomes after heart surgery. It may help doctors provide better care for all patients.
Amsterdam, North HollandAges 18 years+ - NCT06447740Recruiting
Stent vs. medication for narrowed kidney artery
This trial compares placing a tiny mesh tube (stent) to open the narrowed kidney artery versus continuing blood pressure medicines alone. It is for people whose high blood pressure is hard to control even with multiple medications and who have a blockage in the kidney artery that can be treated.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06556446Recruiting
Clot-busting drug after stroke if on blood thinner
This study looks at whether giving a clot-busting medicine (IV thrombolysis) is safe and effective for people who have had a stroke and also recently took a direct oral anticoagulant (DOAC). If you've taken a DOAC in the last 48 hours, this trial may help doctors decide the best treatment for you.
InnsbruckAges 18 years+ - NCT04660747Recruiting
Anticoagulant medication choices for cerebral venous thrombosis
This study looks at people with cerebral venous thrombosis who were treated with blood thinners taken by mouth (or started within the first 30 days). It uses observational data to understand how these treatments are used and what outcomes may follow.
Amsterdam, North HollandAges 18 years+ - NCT06516172Recruiting
The Bern Rehabilitation Registry for Chronic Conditions
This trial is creating a registry to study how people with chronic diseases benefit from rehabilitation programs. If you are an adult with a long-term health condition and have been referred to rehab, your data could help improve care for others.
Heiligenschwendi, Canton of BernAges 18 years+ - NCT05645081Recruiting
Blood test study to predict stroke risk after TIA
This trial studies tiny particles in your blood (called extracellular vesicles) to understand and predict stroke risk after a TIA (a temporary stroke-like episode). It may help doctors identify who is at higher risk using blood samples, rather than only symptoms and scans.
Merthyr TydfilAges 18 years+ - NCT03168659Recruiting
Study of HeartLight during catheter ablation for irregular heartbeat
This study looks at the HeartLight device during a procedure to treat atrial fibrillation (an irregular heart rhythm) that comes and goes. It is meant for adults whose symptoms continue even after trying at least one anti-arrhythmia medicine.
Tucson, ArizonaAges 18 years+ - NCT05845723RecruitingPhase 2
Study drugs for blood-vessel Behçet’s to reduce inflammation
This Phase 2 trial tests tocilizumab and tofacitinib to see if they can better control vascular (blood-vessel) Behçet’s syndrome. It may help by lowering inflammation and reducing complications from aneurysms in the aorta or peripheral arteries.
Beijing, Beijing MunicipalityAges 18–65 - NCT06187441RecruitingPhase 3
Testing a treatment break in multiple myeloma
This trial is for people with multiple myeloma who have already completed 12 cycles of a standard treatment (daratumumab, lenalidomide, and dexamethasone) and are doing well. It tests whether taking a break from treatment is safe and effective, instead of continuing without a break.
's-HertogenboschAges 18 years+ - NCT06520904RecruitingPhase 4
PCSK9 inhibitor for coronary plaque in heart disease
This study tests whether a medication called a PCSK9 inhibitor (a type of drug that lowers bad cholesterol) can improve the buildup of plaque in heart arteries. It may be an option for people with coronary artery disease who have not been helped enough by statins alone.
Ürümqi, XinjiangAges 18–65 - NCT06443151Recruiting
Blood Vessel Health After Spinal Cord Injury
This study looks at how blood vessel health is affected in people with long-term spinal cord injury (over 1 year). It tests whether blood vessel function plays a role in heart and circulatory risk.
Englewood, ColoradoAges 18–89 - NCT06093932RecruitingPhase 4
Songling Xuemaikang Capsules for mild high blood pressure
This study tests whether Songling Xuemaikang Capsules can help lower blood pressure in people with mild hypertension who are not currently on regular medication. It may offer a natural treatment option for managing early-stage high blood pressure.
Beijing, Beijing MunicipalityAges 35–65 - NCT06560983Recruiting
Blood sugar and stroke outcomes over one year
This study watches how blood sugar levels affect recovery and risks over one year in people who come to the ER with a stroke. It aims to help doctors better manage blood sugar during emergency stroke care.
Kathmandu, BagmatiAges 18 years+ - NCT06451146Recruiting
Orbital atherectomy for calcified heart blockages
This trial studies a procedure called orbital atherectomy to treat hardened calcium deposits in heart arteries. It aims to help people with moderately to severely calcified blockages.
Legnica, Lower Silesian VoivodeshipAges 18 years+ - NCT07768761Recruiting
Electrical stimulation exercise for lower limb paralysis
This trial tests whether a muscle exercise program using electrical stimulation can help people with paralysis in their legs. It may improve muscle strength, blood flow, or other health benefits.
Cleveland, OhioAges 18 years+ - NCT01258231Recruiting
Genetic test to predict risks after heart surgery
This study looks for genetic (DNA) clues that may help predict side effects or complications after heart surgery. If you join, your genome information may be used to understand who is at higher risk and why.
Boston, MassachusettsAges 20–90 - NCT07769528Recruiting
Heart pump support for severe heart failure
This study tests a device that helps the heart pump blood when it is too weak to do so, even with medicine, after surgery, or while waiting for a transplant. It aims to see if it's safe and works well.
Beijing, Beijing MunicipalityAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,609 recruiting cardiology studies from the U.S. registry right now, out of 14,617 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Pain
- Injuries & trauma
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.