Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07232069RecruitingPhase 3
Early heart disease trial for women and men with mild plaque buildup
This trial tests whether two medicines, a statin and colchicine, can slow or stop early heart artery plaque from growing in people who have mild plaque but no heart disease symptoms yet. It uses special CT scans to measure plaque over 2 years.
Birmingham, AlabamaAges 30–60 - NCT07105930Recruiting
Comparing two ways to treat heavily calcified heart arteries
This trial tests if a special rotating device alone works as well as a more complex approach for treating heavily calcified blockages in the heart arteries. It uses a CT scan to find the right patients.
FrankfurtAges 18 years+ - NCT05843370Enrolling by invitation
Air pollution and heart/lung health across income and diet
This study looks at how different levels of outdoor air pollution may affect heart and lung health, and how a person’s socioeconomic situation and nutrition might change the risk. You may be asked to do health checks and help the team understand your usual diet and symptoms.
Chapel Hill, North CarolinaAges 25–70 - NCT06086132Recruiting
Preventing heart damage from cancer treatment
This trial tracks how cancer treatments affect the heart. It may help doctors find ways to prevent heart problems during your treatment.
BolognaAges 18 years+ - NCT07063056Recruiting
Curcumin and astaxanthin for lowering triglycerides and inflammation
This trial tests whether two natural supplements, curcumin and astaxanthin, can help lower high triglyceride levels and reduce inflammation. It could be a good fit if you have moderately high triglycerides and are generally healthy.
Dublin, OhioAges 21–59 - NCT07085832Recruiting
CPR skills test after ALS training
This trial checks how well healthcare providers perform CPR after completing an Advanced Life Support (ALS) training course. It aims to see if the training improves their skills in saving lives.
CairoAges 18–70 - NCT07096388Recruiting
Cost comparison of iliac branch stents for aortic aneurysm
This study looks at whether using a special stent (called an iliac branch device) to repair a bulge in your lower aorta or iliac arteries is cost-effective. It compares this newer, less-invasive method to traditional open surgery.
Miano, ItalyAges 18 years+ - NCT06732648RecruitingPhase 2/Phase 3
Testing a new drug for severe brain swelling after a large stroke
This trial tests a new drug called HRS8179 to reduce severe brain swelling after a large stroke. If you have a major stroke on one side of the brain and can start treatment within 10 hours, this study may help prevent dangerous pressure buildup.
Beijing, Beijing MunicipalityAges 18–80 - NCT07561320RecruitingPhase 4
Two ways to treat enlarged veins in your leg
This study compares two minimally invasive procedures to treat enlarged great saphenous veins (a vein in your thigh that can cause swelling, pain, or skin changes). Both procedures seal off the problematic vein by either using heat and mechanical motion or injecting a foaming substance.
São Paulo, São PauloAges 18 years+ - NCT07593794Recruiting
Quality of Recovery After Heart Surgery Study
This study measures how well patients recover after planned heart surgery by having them answer questions about their physical and emotional wellbeing. The goal is to understand what affects recovery so doctors can better support patients afterward.
KocaeliAges 18 years+ - NCT07667465Recruiting
Single-lead ECG test for heart electrical intervals
This trial is testing a new algorithm that uses a simple, one-lead ECG (heart tracing) to measure how fast electrical signals travel through the heart. Researchers want to see if the algorithm works well in people whose heart intervals are slightly outside the normal range, which may help doctors better monitor heart conditions.
Hangzhou, ZhejiangAges 18 years+ - NCT06387147RecruitingPhase 3
Oral antibiotics for acute mesenteric ischemia
This trial tests whether taking oral antibiotics (gentamicin and metronidazole) can treat acute mesenteric ischemia caused by an artery blockage, instead of using IV antibiotics. It's for people who don't need emergency surgery and don't have a serious infection.
Clichy, FranceAges 18–90 - NCT06388226Recruiting
Leg heat therapy for heart failure with preserved pumping ability
This study tests if applying heat to your legs can improve symptoms and heart function in people with a type of heart failure where the heart pumps normally but doesn't relax properly. It aims to find a simple, drug-free way to help you feel better.
Indianapolis, IndianaAges 18 years+ - NCT06969547Recruiting
Heart muscle coordination and microvessel function SPECT study
This study uses a special heart scan (SPECT) to look at how well the heart muscle is squeezing and how well the tiny blood vessels in the heart are working. It may help doctors understand why some people have chest pain even when their main arteries are not blocked.
TomskAges 18–75 - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT06154395Recruiting
Improving heart blood flow after a first heart attack
This study tests a way to improve blood flow in the small vessels of the heart after a first heart attack. It is for people who have a specific type of heart attack in the front part of the heart and are treated quickly with a catheter procedure.
Harbin, HeilongjiangAges 18 years+ - NCT06740396Recruiting
Depression in heart disease patients in Baghdad
This study looks at how common depression is in people with coronary artery disease and how severe it is. If you have heart disease and are being treated at a hospital in Baghdad, you can help doctors understand the link between heart health and mental health.
BaghdadAges 18 years+ - NCT06992089Recruiting
Pacemaker study for heart failure with low heart rate
This trial tests a special pacemaker setting to help your heart beat faster during exercise. It may improve your ability to be active if you have heart failure with preserved ejection fraction (HFpEF) and a low resting heart rate.
ValenciaAges 18 years+ - NCT07548723Enrolling by invitation
Nerve Stimulation Device Reliability Study
This study tests how reliably a small ear-stimulation device measures heart-rhythm patterns. Researchers want to see if the device gives consistent readings across multiple measurement sessions, which could help doctors monitor heart health in the future.
SinopAges 18–40 - NCT07531784Recruiting
Blood Test to Detect Heart Rejection After Transplant
This Swedish study tests whether a simple blood test can detect early signs that your body is rejecting a transplanted heart. The test looks for DNA fragments in your blood that may signal rejection before symptoms appear, potentially helping doctors catch problems sooner.
StockholmAges 18 years+ - NCT06934473Recruiting
How a gut hormone affects blood pressure after eating in healthy adults
This study looks at how a natural gut hormone called GIP affects blood pressure after a meal. It may help find new ways to treat blood pressure problems after eating.
Copenhagen, HellerupAges 18–40 - NCT07075445Recruiting
Living with long QT syndrome types 2 and 3
This study looks at how long QT syndrome types 2 and 3 affect your daily life and health. It asks you to wear a smartwatch and answer questions to help researchers understand the challenges you face.
Greenville, North CarolinaAges 18 years+ - NCT06287619RecruitingPhase 2
IV iron after heart surgery for iron deficiency
This trial tests whether giving iron through a vein after heart surgery can help fix low iron levels and improve recovery. It is for people who have iron deficiency (with or without anemia) before their planned heart surgery.
Kingston, OntarioAges 18 years+ - NCT06637644Recruiting
Impella RP Flex device registry
This registry collects information about people who have used the Impella RP Flex device, a heart pump that helps support blood flow. Your data will help doctors learn more about how this device works in real-world patients.
Birmingham, AlabamaAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.