Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,973 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2481
- Phase 4480
- Phase 3447
- Phase 1360
- Phase 1/Phase 2162
- Phase 2/Phase 386
Top conditions
- Stroke843
- Heart Failure565
- Hypertension399
- Cardiovascular Diseases390
- Coronary Artery Disease373
- Multiple Myeloma333
- Atrial Fibrillation268
- Ischemic Stroke200
- Atrial Fibrillation (AF)140
- Acute Ischemic Stroke138
- Myocardial Infarction101
- Pulmonary Hypertension100
- Stroke, Ischemic86
- Congenital Heart Disease85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California461
- Alabama197
- Massachusetts183
- Arizona173
- New York161
- Florida145
- Maryland120
- Minnesota120
- Illinois119
- Texas118
Recruiting studies9,970 total
- NCT07549165Recruiting
How the IVC changes during back stabilization surgery
This study measures a large vein in your belly (the IVC) during planned lumbar spine stabilization surgery to understand how it responds to the surgery. The goal is to improve how doctors monitor your blood circulation during the operation.
TrabzonAges 18 years+ - NCT07041359RecruitingPhase 4
Traditional Chinese medicine for elderly heart disease patients with ongoing symptoms
This trial tests whether traditional Chinese medicine can help elderly patients with coronary heart disease who still have chest pain or discomfort despite standard treatments. It focuses on those who cannot have or have not fully benefited from procedures like stents or bypass surgery.
Beijing, Beijing MunicipalityAges 75–90 - NCT06632613RecruitingPhase 2
Trial of ENN0403 to prevent kidney injury after heart surgery
This study tests a new drug (ENN0403) given during heart surgery to see if it prevents acute kidney injury—a sudden drop in kidney function. The trial is for people who are already at higher risk due to their specific heart surgery and other health factors.
ShanghaiAges 18–85 - NCT07042321Recruiting
Risk factors for blocked heart vessels after emergency angioplasty
This study looks at why some people develop micro-blockages in the heart's small blood vessels after emergency angioplasty (PCI) for a heart attack. If you join, you'll help doctors understand these risks and maybe prevent future problems.
Changsha, Hunan Province,ChinaAges 18 years+ - NCT07591298RecruitingPhase 2
SYH2070 injection for homozygous familial high cholesterol
This study tests a new injectable medication (SYH2070) designed to lower cholesterol in people with homozygous familial hypercholesterolemia—a genetic condition that causes extremely high cholesterol levels despite treatment. The goal is to see if this drug safely reduces cholesterol better than current options.
Changsha, HunanAges 18 years+ - NCT07575503Recruiting
Advanced CT scan to detect small blood clots in the lungs
This study tests a new type of CT scan (photon-counting CT) to see if it's better at finding small blood clots in the lungs. If you have symptoms like sudden shortness of breath, chest pain, or fainting and doctors suspect a blood clot, this trial may help confirm the diagnosis with clearer images.
Hangzhou, ZhejiangAges 18 years+ - NCT07541222Recruiting
Blood pressure medications and surgery recovery outcomes
This study looks at how blood pressure medications affect low blood pressure episodes that happen during and after heart surgery. Researchers want to understand if the number of blood pressure drugs you take before surgery changes how your body handles blood pressure during the operation.
KonyaAges 40 years+ - NCT07335510Recruiting
Baroreflex therapy for heart failure patients
This trial tests a device that stimulates a nerve in your neck to help your heart pump better. It is for people with heart failure and a weak heart pump who still have symptoms despite taking medications.
San Francisco, CaliforniaAges 18 years+ - NCT06776458Recruiting
Aromatase inhibitor effects on heart and brain health in breast cancer
This study looks at how aromatase inhibitors (a type of hormone therapy for breast cancer) affect your heart and brain health over time. It compares women with breast cancer who have taken these drugs to healthy women of similar age.
Toronto, OntarioAges Any age - NCT06422845Recruiting
Drug-coated balloon for dialysis fistula narrowing
This trial tests a special balloon that releases medication to help keep your dialysis fistula (the blood vessel used for treatment) open longer if it has narrowed. It may be a good option if you have a blockage in the vein side of your fistula that causes problems during dialysis.
Hefei, AnhuiAges 18–80 - NCT05775484Recruiting
Exercise program to slow heart and blood vessel aging
This trial tests whether a structured exercise program can slow how quickly your cardiovascular system (heart and blood vessels) “ages” over time. If you’re able to move around outdoors safely, exercise may be a key part of the study.
Singapore, SingaporeAges 21–100 - NCT07595809Recruiting
Diet and exercise for heart failure with weak heart pumping
This study tests whether combining a healthy eating plan (DASH diet) with supervised exercise can help people with heart failure where the heart doesn't pump strongly enough. The goal is to see if these lifestyle changes improve heart function and symptoms.
Zabrze, Silesian VoivodeshipAges 30 years+ - NCT06956911Enrolling by invitation
Low-resistance exercise with blood flow restriction after heart surgery
This trial tests if gentle arm exercises with a special blood pressure cuff can help men recover their lung function after heart surgery. It may be an option for those who are stable and ready to follow simple instructions.
Cairo, Cairo GovernorateAges 45–60 - NCT07068776Recruiting
Shockwave therapy to improve leg wound healing after bypass surgery
This trial tests if using shockwave therapy on leg veins during coronary artery bypass surgery can help the leg wound heal better. It may be a good fit if you need 2 or more vein grafts and have stable kidney function.
Innsbruck, TyrolAges 18 years+ - NCT06503640Recruiting
Microvascular dysfunction in angina patients
This study tests if chest pain with clear arteries is caused by tiny heart vessel problems. It may help find better treatments for patients whose arteries look normal on angiograms.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07529275Recruiting
iCover Stent Safety and Performance in Complex Aortic Aneurysm Repair
This trial tests a special covered stent (iCover) used during a minimally invasive procedure to repair complex abdominal aortic aneurysms—life-threatening bulges in the main artery in your belly. The stent helps keep important blood vessels open during the repair.
BonheidenAges 55 years+ - NCT06058676Enrolling by invitation
Predicting blood flow changes after carotid stenting
This study looks at why some people have too much blood flow to the brain after a procedure to open a blocked neck artery. It uses special tests to check how well your brain controls its own blood flow, with the goal of predicting and preventing problems.
Beijing, Beijing MunicipalityAges 18–80 - NCT06683001Recruiting
National heart failure registry
This study is creating a registry of people with chronic heart failure to better understand the condition. If you have any stage of chronic heart failure, you may be able to join.
MoscowAges 18 years+ - NCT07125417RecruitingPhase 4
Blood thinner comparison after left atrial appendage closure
This study compares two approaches after a left atrial appendage closure (LAAC) procedure: taking no blood thinner versus taking just one antiplatelet medication. It aims to see which option is safer for people with atrial fibrillation who are at risk for bleeding.
Nagoya, Aichi-kenAges Any age - NCT06970925RecruitingEarly Phase 1
Iron supplement after heart surgery study
This trial tests whether a special iron supplement (Sucrosomial® Iron) helps patients recover from heart surgery better than standard care. It is for people who have low iron or anemia after their planned heart surgery.
Englewood, New JerseyAges 18 years+ - NCT07721636Recruiting
Vexus ultrasound to set dry weight in dialysis
This trial uses a special ultrasound scan (VEXUS) to help doctors find the right 'dry weight' for people on hemodialysis. The goal is to remove just the right amount of fluid without strain.
AlexandriaAges 25–65 - NCT05754138Recruiting
Testing sports safety with a subcutaneous defibrillator
This study looks at whether it is safe to play sports if you have a specific type of implanted defibrillator under the skin. It will track your device performance and exercise habits, using home monitoring, to understand any risks from sports.
Tel AvivAges 10–60 - NCT07128849Recruiting
Upper arm exercise after heart bypass surgery
This study tests whether adding arm cycling exercises to standard recovery helps people recover better after a coronary artery bypass graft (CABG, also known as heart bypass surgery). It is for patients who are stable enough to start moving soon after surgery.
Lahore, Punjab ProvinceAges 40–65 - NCT06968650Recruiting
Cocooned Moms Support Study
This study tests a program that offers extra support to Black women during pregnancy. It aims to help moms feel safe, connected, and healthy.
Miami, FloridaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,973 recruiting cardiology studies from the U.S. registry right now, out of 15,205 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
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- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.