Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT06488352Recruiting
Enhancing care study for heart bypass patients
This trial looks at people who had coronary artery bypass graft (CABG) surgery between 2013 and 2023 to see if better care can improve their recovery. It may help if you had a planned bypass and stayed in the hospital longer than 3 days.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07380217Recruiting
Using heart pump support for complex high-risk procedures
This trial is testing whether using a special heart pump (PulseCath iVAC2L) during complex, high-risk angioplasty can help people with very weak hearts. It's for people who need a procedure for complicated coronary artery blockages.
AmsterdamAges 18 years+ - NCT07329842Recruiting
Bed height and CPR quality in pediatric simulation
This trial tests how the height of a hospital bed affects chest compression quality and the physical strain on doctors during CPR on a child-sized manikin. It may help find the optimal bed height to improve CPR effectiveness.
Antalya, AntalyaAges 18 years+ - NCT07327606Recruiting
Heart, kidney, and metabolism health study
This study follows people with different stages of heart-kidney-metabolic syndrome to understand what factors affect their health over time. It aims to find better ways to predict and manage the condition.
Beijing, Beijing MunicipalityAges 18–85 - NCT06539767Recruiting
Brain aneurysm risk study using MRI
This study looks at people with brain aneurysms to understand which ones are more likely to cause problems. It uses a special MRI to get detailed images and help predict risk.
Guangzhou, GuangdongAges 18–80 - NCT06667505Recruiting
Testing an online education program for ICD patients
This trial tests an online educational program designed to help people with heart failure who have or are waiting for an ICD (a device that helps control heart rhythm). It includes patients, their caregivers, and healthcare professionals to see if the program improves understanding and outcomes.
Belfast, County AntrimAges 18 years+ - NCT06492044Recruiting
Testing right heart strain to predict fluid response in septic shock
This study tests whether measuring the strain (stretch) of the right upper heart chamber with ultrasound can predict if a patient with septic shock will benefit from more fluids. Septic shock is a severe infection that causes very low blood pressure and organ damage.
AmiensAges 18 years+ - NCT06535529RecruitingPhase 3
Comparing Two Water Pills for Worsening Heart Failure
This study compares two medicines—acetazolamide and dapagliflozin—to see which works better at removing extra fluid in people hospitalized for worsening heart failure. It may help decide the best treatment for fluid overload.
CairoAges 18 years+ - NCT06978348Recruiting
AI model to predict stroke using ultrasound
This trial is building an AI tool to predict ischemic stroke risk based on carotid and vertebral artery ultrasound findings. It may help find early warning signs of a stroke before it happens.
Shanghai, Shanghai MunicipalityAges Any age - NCT05729009Recruiting
Testing blood-vessel function changes after heart transplant
This study looks at how tiny blood vessels in the body work over time in people who have had a heart transplant. It aims to better understand changes in blood flow and how these may relate to health after transplant.
Rio de JaneiroAges 18–75 - NCT07315178Recruiting
Digital twin study for chronic aortic dissection
This study is creating a digital twin model to predict how chronic thoracic aortic dissection progresses. If you have a type A or type B aortic dissection, this study may help researchers better understand your condition without additional stress or invasive procedures.
DijonAges 18 years+ - NCT06885970Recruiting
Cytisine for smoking cessation and heart health
This study tests whether a medicine called cytisine can help people quit smoking and how it might affect their heart health. If you are a smoker without serious heart, liver, kidney, or immune problems, you may be able to join.
Athens, HaidariAges 18–75 - NCT06891482Enrolling by invitation
Home exercise program for dialysis patients
This trial offers a home-based exercise program using technology (like a smartphone app) to help people on dialysis stay active and improve their health. It's designed for Dutch-speaking adults who are stable and willing to try a 6-month program.
Hasselt, HasseltAges Any age - NCT07293533Enrolling by invitation
Heart bypass risk study for planned surgeries
This study looks at patient data from people who had a planned coronary artery bypass graft (heart bypass) to create a better way to predict risks. It may help future patients understand their own surgery risks.
Fortaleza, CearáAges 18 years+ - NCT06330675Recruiting
Early mobilization after pacemaker or ICD implant
This trial is testing whether getting up and moving earlier after a pacemaker or defibrillator implant is safe and helpful. If you are getting a new device for the first time, you may be able to join.
LuganoAges 18 years+ - NCT06797804Recruiting
Horticultural therapy for older adults in long-term care
This study tests if an app-guided gardening program can improve heart health, reduce stress and depression, and boost happiness in older adults living in nursing homes. It aims to see if these sessions can help you feel better overall.
TaipeiAges 65 years+ - NCT06897514Recruiting
Testing a device to predict low blood pressure during surgery
This trial is testing a non-invasive device that predicts low blood pressure during surgery. It aims to help doctors prevent dangerous drops in blood pressure, making surgery safer for patients.
SeoulAges 19 years+ - NCT05718245Recruiting
HEPA air filters to improve heart and blood sugar health
This study looks at whether using HEPA air filters and monitoring indoor air can improve heart-related health and blood sugar/metabolic health in older adults. You may be eligible if you live in Los Angeles County, don’t smoke, and meet the health and home requirements.
Los Angeles, CaliforniaAges 65–84 - NCT07297641Recruiting
Imaging-guided vs X-ray-guided PCI for blocked stents
This trial compares two ways to guide a procedure to reopen a stent that has narrowed again: using a special camera inside the artery (IVUS) versus standard X-ray (angiography). It aims to see which approach works better for people who have a drug-eluting stent that is narrowing for the first time.
Nanjing, JiangsuAges 18–80 - NCT07586111Recruiting
Plant Foods for Better Gut and Heart Health
This study tests whether eating more plant-based foods improves your gut bacteria, digestion, and heart health markers. You'll follow a structured diet plan for several weeks while providing blood, stool, and urine samples to measure changes.
LondonAges 30–70 - NCT06884098RecruitingPhase 1
A study comparing two versions of a medicine in healthy adults
This trial tests a new version of a medicine (AD-228B) against the original (AD-2284) to see how they work in the body and if they are safe. Healthy volunteers are needed.
SeoulAges 19 years+ - NCT07483125Recruiting
Blood pressure drop during Valsalva in hypertrophic cardiomyopathy
This study looks at how blood pressure changes during a simple breathing exercise (the Valsalva maneuver) in people with hypertrophic cardiomyopathy, a condition where the heart muscle is thickened. It aims to understand if this test can help detect a specific type of blockage in the heart's main pumping chamber.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05570721Recruiting
Study of depression, stress, and heart health in late menopause
This study looks at how depression and stress connect to heart health in women going through the late stages of menopause. It may help researchers understand what factors affect heart risk during this life stage, including how symptoms and daily life relate to heart measurements.
Chapel Hill, North CarolinaAges 44–55 - NCT07293858Recruiting
Eye scan study for heart artery patients
This study looks at special eye scans (OCT) to see if they can help doctors predict how heart patients will do. It also uses artificial intelligence to analyze the scans. If you have had this type of scan during a heart procedure, you might be able to join.
Nijmegen, GelderlandAges Any age
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.