Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT05740397Recruiting
Testing blood pressure targets during heart-lung bypass
This trial compares different strategies for keeping a specific blood pressure level during heart-lung bypass surgery. It may help reduce complications by finding the safest blood pressure target during the operation.
VeronaAges 18–80 - NCT05954559RecruitingPhase 4
MRI study testing a strong-contrast heart scar scan agent
This Phase 4 study checks whether a stronger MRI contrast dye (given in a higher “relaxivity” form) can better help doctors assess heart muscle scar tissue. You may be eligible if you already joined a prior similar MRI contrast study and can safely undergo another heart MRI.
Baltimore, MarylandAges 21 years+ - NCT05958290Recruiting
Lifelong antibiotics versus stopping antibiotics after device infection
This trial studies whether people with an implanted heart device infection should take antibiotics for life or stop antibiotics and monitor closely. It is for situations where doctors think removing the device is not a safe or suitable option.
Copenhagen, Capital RegionAges Any age - NCT07380854Recruiting
Thyroid Hormone After Heart Bypass for Mild Underactive Thyroid
This study looks at whether giving thyroid hormone replacement to people with mild underactive thyroid (subclinical hypothyroidism) after heart bypass surgery improves their recovery. It is for adults who are scheduled for bypass surgery and have not recently used thyroid or anti-thyroid medications.
Seongnam-siAges 19–90 - NCT06601582Recruiting
Blood recovery during heart surgery study
This trial tests if a machine that collects and reuses blood during heart surgery can help patients avoid needing donor blood transfusions. It is for people having a first-time coronary bypass or heart valve surgery.
Recife, PernambucoAges 18 years+ - NCT07399587RecruitingPhase 2/Phase 3
Optimizing heart failure treatment with two devices
This study tests whether using two implanted devices (CardioMems and BaroStim) can improve heart function and symptoms in people with advanced heart failure. It aims to help patients who are already on standard medications get even better results.
Riverhead, New YorkAges 18–80 - NCT06601270Recruiting
SCAD registry: tracking spontaneous coronary artery dissection
This study collects information from people diagnosed with spontaneous coronary artery dissection (SCAD) in the last 10 years. It aims to learn more about this rare heart condition to improve future care.
Buenos AiresAges 18 years+ - NCT06685237Recruiting
Copenhagen heart failure with preserved pumping study
This study is for people in the Capital Region of Denmark who are at least 50 years old and have certain health conditions that put them at risk for a type of heart failure where the heart pumps normally but doesn't relax properly. The study aims to find and help people before heart failure develops.
HellerupAges 50–89 - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75 - NCT07737561Recruiting
Exercise test for heart, kidney, and metabolic health
This study looks at how blood pressure and artery stiffness respond to exercise in people with heart, kidney, and metabolic problems. It may help doctors better understand your condition.
KaramanAges 18 years+ - NCT06596304Recruiting
How blood vessels respond to exercise with and without blood flow restriction
This study looks at how your blood vessels respond to resistance exercise (like weight lifting) with and without a technique called blood flow restriction. It compares younger and older adults to understand how aging affects these responses.
Almada, Monte Da CaparicaAges 18 years+ - NCT06592196Recruiting
Statin liver safety in neurology patients
This study is looking at the safety of statin medications (cholesterol-lowering drugs) on the liver in people hospitalized for neurological conditions like stroke, headache, or dizziness. The goal is to see if these drugs are safe for this group of patients.
Shanghai, Shanghai MunicipalityAges 18–85 - NCT06588595RecruitingPhase 4
Switching Blood Thinners After Stent Placement
This study compares two ways to manage blood thinners after a stent. It tests whether switching from stronger drugs (prasugrel or ticagrelor) to clopidogrel is safe and effective for long-term heart protection.
Jacksonville, FloridaAges 18 years+ - NCT06569212RecruitingPhase 4
Beta-blocker to reduce heart damage after brain bleed
This trial tests whether a common beta-blocker (metoprolol) can protect the heart from injury and reduce inflammation after a bleed in the brain (subarachnoid hemorrhage). It may help patients recover better after this type of stroke.
Portland, MaineAges 18 years+ - NCT07657650Recruiting
Imaging test for heart failure patients before revascularization
This trial uses a special imaging scan to see if heart muscle has damage from blocked arteries. It helps doctors decide if a procedure to open blocked arteries might improve your heart function.
BeijingAges 18 years+ - NCT06579326Recruiting
Using light and sound to check leg artery health
This trial uses a special imaging test (photoacoustic tomography) to see how well blood flows in the legs. It is for people with or without peripheral artery disease (PAD) to help improve diagnosis.
Guangzhou, GuangdongAges 18 years+ - NCT07732114Recruiting
Liver vein vs. heart echo to check right heart function on a ventilator
This study compares a liver vein ultrasound method with a standard heart ultrasound for checking how well the right side of the heart is pumping in patients who are on a breathing machine (ventilator). If you are on a ventilator and can get a clear ultrasound of your heart and liver veins, you may be able to join.
Alexandria, Shebin El-KomAges 18 years+ - NCT06567106Recruiting
Heart function study with gentle ultrasound
This trial uses low-intensity ultrasound to see if it can safely measure or affect heart function in healthy people. It aims to understand how the heart works during a simple, non-invasive procedure.
ShanghaiAges 18–65 - NCT05984537RecruitingPhase 4
Bivalirudin during angioplasty for high-risk heart plaques
This study tests whether a blood thinner called bivalirudin, given during a procedure to open blocked heart arteries (PCI), helps blood flow better in the tiny vessels of the heart afterward. It is for people with a recent unstable heart condition and a high-risk plaque seen on a CT scan.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06951685Recruiting
Testing a new blood vessel for leg bypass surgery
This trial tests a new type of artificial blood vessel (called the XPAD conduit) for people who need a bypass in their leg above the knee. It aims to see if it can safely restore blood flow and improve symptoms like leg pain or wounds.
San JoséAges 18 years+ - NCT07455214Recruiting
Heart rate variability and breathing trial success in ventilated patients
This study looks at whether heart rate patterns can help predict if a person on a breathing machine is ready to breathe on their own. It may help doctors decide the best time to try removing the breathing tube.
New Taipei CityAges 18–85 - NCT07729891Recruiting
Vital sign monitoring after urological surgery
This study tests a system that constantly watches your vital signs (like heart rate and blood pressure) after urological surgery, to catch problems early. It's for people who are not expected to need the Intensive Care Unit after their operation.
Parma, ParmaAges 18 years+ - NCT06560294Recruiting
Glue injection vs watchful waiting for pelvic congestion syndrome
This trial compares a new glue injection treatment (embolization) with no active treatment for pelvic congestion syndrome. It aims to see if the glue procedure reduces pelvic pain and varicose veins better than just monitoring symptoms.
Tanta, ElGharbiaAges 30–50 - NCT06575530RecruitingPhase 4
Remimazolam for sedation after non-cardiac surgery
This trial tests a sedative called remimazolam besylate in patients who need a breathing tube and light sedation after non-cardiac surgery. The goal is to see if it works well and is safe.
Beijing, Beijing MunicipalityAges 18–64
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.