Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07671677Recruiting
BodyGuardian monitoring after AF ablation
This study tests using a portable heart monitor called BodyGuardian to check for atrial fibrillation returning after a procedure called ablation. It may help your doctor find irregular heartbeats early.
Delray Beach, FloridaAges 18 years+ - NCT07668206Recruiting
Talking therapy for thoracic outlet syndrome pain
This study tests if talking with a counselor (motivational interviewing) can help people with long-term pain from thoracic outlet syndrome feel better. It is for adults who have not had surgery recently.
AnkaraAges 18–65 - NCT07664748Recruiting
Voice check-ins for heart failure monitoring
This study tests whether analyzing your voice during routine check-ins can help monitor heart failure. You'll use a special app or device to talk to a virtual assistant, which may help detect early signs of worsening heart failure.
Milan, ItaAges 18 years+ - NCT07670325Recruiting
Knee device for walking rehab after stroke
This trial tests a knee device that helps people walk better after a stroke. It is for people who had a stroke within the last 2 years, can walk with some help, and meet basic height and weight limits.
Roma, RMAges 18 years+ - NCT07669987Recruiting
Heart bypass surgery and artery imaging study
This study looks at whether a special imaging test called QFR, done before heart bypass surgery, can help predict how well the radial artery graft will work shortly after surgery. If you have severe blockages in your heart arteries and are scheduled for bypass surgery, this trial may be relevant.
Beijing, Beijing MunicipalityAges 18–80 - NCT06673953Recruiting
Breathing training for heart surgery recovery with neck posture problems
This trial tests whether a breathing exercise device can improve heart and lung function in men who had heart bypass surgery at least 3 months ago and also have neck pain from poor posture. It may help you breathe better and feel stronger after surgery.
Giza, Giza GovernorateAges 45–55 - NCT03001180Recruiting
Study blood and tissue markers in vascular anomalies
This study collects extra blood (and sometimes tissue during procedures) to look for markers that can help doctors better understand vascular anomalies. It may not be a treatment, but it can improve future care by finding patterns linked to the condition.
Boston, MassachusettsAges 1 day+ - NCT05598632Recruiting
People with atrial fibrillation registry to study stroke risk
This registry study follows people with atrial fibrillation to learn which risk factors are linked to stroke or blood clots traveling through the body. Your information helps improve how doctors predict risk and choose prevention strategies.
Beijing, Beijing MunicipalityAges 18–120 - NCT05527717RecruitingPhase 4
PCI vs strategy for heart attack shock needing ECMO
This study looks at the best way to reopen blocked heart arteries (using a stent procedure) in people who had a heart attack complicated by severe shock and need a life-support machine called VA-ECMO. It may help improve outcomes by testing which revascularization approach works best for multi-vessel blockages.
SeoulAges 19 years+ - NCT06023186Recruiting
Effect of mavacamten on heart blood flow in HCM
This study tests whether the drug mavacamten (Camzyos) improves blood flow in the heart's small vessels for people with obstructive hypertrophic cardiomyopathy. You will take mavacamten as prescribed and have a PET/CT scan to measure your heart's blood flow reserve.
Charlottesville, VirginiaAges 18–85 - NCT05452720Recruiting
Testing a new pulmonary valve replacement in children
This study tests an early, first-use version of a new pulmonary valve device for children whose own valve is not working well. It may help improve blood flow from the heart to the lungs and aims to learn how safe and effective the valve is over time.
Peoria, IllinoisAges birth–22 years - NCT06040073Recruiting
Study of heart artery blockages after heart attack
This study is for people who recently had a heart attack and need an angiogram. It looks at blockages that are not completely blocking blood flow to learn how they change over time.
BeijingAges 18 years+ - NCT06334549RecruitingPhase 4
Vasopressor study on brain oxygen during surgery
This study tests how a blood-pressure medicine called a vasopressor affects oxygen levels in the brain during general anesthesia for abdominal surgery. It may help patients understand the safest way to manage blood pressure during their operation.
Dalian, LiaoningAges 18–80 - NCT06146660Recruiting
Mavacamten safety study in Korean patients with oHCM
This study checks how safe the drug mavacamten is for Korean patients with a type of heart disease called obstructive hypertrophic cardiomyopathy (oHCM). It is for people who are already prescribed the drug by their doctor.
SeoulAges 19 years+ - NCT06676553RecruitingPhase 4
Optimized kidney nerve treatment for high blood pressure
This trial tests a new way to perform a procedure called renal denervation, which uses radio waves to calm overactive kidney nerves that can raise blood pressure. By getting feedback during the procedure, doctors hope to make the treatment more effective for people with high blood pressure.
TaipeiAges 18 years+ - NCT06673602RecruitingPhase 4
Herbal capsule for memory problems after bleeding stroke
This trial tests a Chinese herbal capsule called Fufang Congrong Yizhi Capsule (FCYC) to see if it can help with memory and thinking problems that start after a bleeding stroke. It is for people who have had robot-assisted surgery for their stroke and also fit a specific pattern in traditional Chinese medicine.
Beijing, Beijing MunicipalityAges 18 years+ - NCT05332691Recruiting
Beating-heart septal myectomy for thick-heart blockage
This trial studies surgery that removes part of the thick heart muscle while the heart is still beating to relieve a blockage that makes blood leaving the heart harder. It may help people with hypertrophic obstructive cardiomyopathy whose symptoms persist despite medication.
Wuhan, HubeiAges 8 years+ - NCT05321875RecruitingPhase 3
Candesartan to prevent heart failure in certain gene carriers
This trial tests whether candesartan (a blood-pressure medicine) can delay or prevent heart muscle weakening in people who carry a disease-causing dilated cardiomyopathy gene variant but still have fairly strong heart pumping. Participants are randomly assigned to candesartan or a placebo to see which one keeps the heart healthier over time.
Majadahonda, MadridAges 18–64 - NCT06519747Recruiting
Detecting irregular heartbeat after non-heart surgery
This trial uses a monitoring device to check for a common but often overlooked irregular heartbeat (atrial fibrillation) after non-cardiac surgery. The goal is to detect and treat it early to prevent complications like stroke.
Hamilton, OntarioAges 18–120 - NCT06551129Recruiting
Camzyos treatment in real life: patient experiences
This study tracks how people with obstructive hypertrophic cardiomyopathy feel and function while taking Camzyos (mavacamten). It aims to understand the real-world effects of the medication beyond clinical trials.
Boston, MassachusettsAges 18 years+ - NCT07657676RecruitingPhase 4
Study of mazdutide for heart artery plaque in people who are overweight
This study tests whether mazdutide, a medicine that may help with weight and blood sugar, can reduce plaque buildup in the heart's arteries. It is for people who are overweight or obese and have some narrowing in their heart arteries but do not need immediate procedures like stents.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07660419Recruiting
Home cardiac rehab app for coronary plaque
This trial tests whether a smartphone-based home cardiac rehabilitation program can help slow or reverse plaque buildup in people with mild-to-moderate coronary artery narrowing. It may be an option if you have stable heart disease and can exercise at home with remote monitoring.
BeijingAges 18–70 - NCT07658534RecruitingPhase 2/Phase 3
Ziresovir for high-risk adults with RSV
This trial tests an antiviral drug called Ziresovir in adults with RSV who have health conditions that make them high-risk, such as lung disease, heart disease, or a weakened immune system. It aims to see if the drug can reduce symptoms like coughing and shortness of breath.
Beijing, Beijing MunicipalityAges 18–85 - NCT07658651Recruiting
Plug for type B aortic dissection repair
This trial tests a special plug (WeFlow-EndoSeal) placed into the false channel of a type B aortic dissection to help seal it. It is for people who are already getting a stent-graft and aims to improve the repair.
Beijing, Beijing MunicipalityAges 18–80
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.