Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,610 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3437
- Phase 1350
- Phase 1/Phase 2160
- Phase 2/Phase 387
Top conditions
- Stroke796
- Heart Failure534
- Hypertension389
- Cardiovascular Diseases373
- Coronary Artery Disease363
- Multiple Myeloma327
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease84
- Peripheral Arterial Disease80
- Stroke, Ischemic78
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital68
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California451
- Alabama195
- Arizona181
- Massachusetts173
- New York168
- Florida140
- Texas122
- Maryland118
- Minnesota117
- Illinois111
Recruiting studies9,610 total
- NCT07658534RecruitingPhase 2/Phase 3
Ziresovir for high-risk adults with RSV
This trial tests an antiviral drug called Ziresovir in adults with RSV who have health conditions that make them high-risk, such as lung disease, heart disease, or a weakened immune system. It aims to see if the drug can reduce symptoms like coughing and shortness of breath.
Beijing, Beijing MunicipalityAges 18–85 - NCT07658651Recruiting
Plug for type B aortic dissection repair
This trial tests a special plug (WeFlow-EndoSeal) placed into the false channel of a type B aortic dissection to help seal it. It is for people who are already getting a stent-graft and aims to improve the repair.
Beijing, Beijing MunicipalityAges 18–80 - NCT06679777Recruiting
Swedish heart and lung imaging study 2
This study invites people who already took part in the first SCAPIS study to have follow-up heart and lung imaging. It helps researchers learn how these organs change over time.
GothenburgAges Any age - NCT06678594Recruiting
A standardized method for treating hardened heart artery blockages
This trial is testing a new step-by-step approach (algorithm) to treat hardened, calcified blockages in heart arteries during a stent procedure. The goal is to see if this standardized method helps improve outcomes for patients with these tough-to-treat blockages.
DublinAges 18 years+ - NCT07662317Recruiting
Heart surgery recovery registry study
This study collects information from people having heart surgery to help doctors learn more about recovery. If you are scheduled for surgery during the study period, you may be able to join.
Hangzhou, ZhejiangAges Any age - NCT07656259Recruiting
Comparing breathing support methods in the heart ICU
This study compares different ways to support breathing in patients who need a ventilator in the cardiac intensive care unit. It aims to find the best approach for people with certain heart conditions, like cardiogenic shock or heart failure.
Rochester, MinnesotaAges 18 years+ - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT07655479Recruiting
Switching to a stronger heart pump after heart attack
This trial tests whether switching to a more powerful heart pump (Impella 5.5) within 24 hours of a heart attack helps people whose hearts are still struggling despite a standard pump. It may be an option for patients who had a heart attack, received an Impella CP pump, but still need strong medication to keep blood flowing.
Düsseldorf, North Rhine-WestphaliaAges 18–77 - NCT07657312RecruitingPhase 2
Infliximab to prevent side effects during myeloma treatment
This trial tests if infliximab, a drug that calms the immune system, can prevent cytokine release syndrome (a serious side effect) when patients receive teclistamab or talquetamab for multiple myeloma that has returned or not responded to treatment.
Columbus, OhioAges 18 years+ - NCT07657546Recruiting
MCG for chest pain without severe blockages
This trial tests a new way to measure blood flow in the heart, called MCG, for people who have chest pain but no severe blockages in their arteries. If you have symptoms like angina and your tests show only mild narrowing, you may be able to join.
Jinan, ShandongAges 18 years+ - NCT07658989Recruiting
Blood thinners in pregnancy with mechanical heart valves
This study looks at the best way to manage blood thinners for pregnant people who have mechanical heart valves. It aims to find the safest approach for both the mother and the baby.
Toronto, OntarioAges 18–45 - NCT07658222Recruiting
Understanding heart changes in advanced cirrhosis
This study is looking at how cirrhosis affects the heart (called cirrhotic cardiomyopathy). It aims to understand the connection between advanced liver disease and heart function, which may help improve care for people with cirrhosis.
Nashville, TennesseeAges 18 years+ - NCT07656818Recruiting
Cold plasma to lower risk of chronic subdural hematoma coming back
This trial tests if a special cold plasma treatment applied during surgery can reduce the chance of a chronic subdural hematoma (a slowly growing blood collection on the brain) from returning. It may help people who already need surgery for this condition.
Ocoyoacac, State of MexicoAges 18 years+ - NCT07663357Recruiting
Blood test to detect heart damage from breast cancer treatment
This study looks at whether a simple blood test can spot early signs of heart damage from certain breast cancer treatments (anthracycline chemo or anti-HER2 drugs). The goal is to protect your heart while you get the cancer treatment you need.
Fortaleza, CearáAges 18 years+ - NCT07662603Recruiting
Breathing exercise program for teens with Behcet's after lung surgery
This trial is for teenagers with Behcet's disease who have had a specific lung surgery to remove a clot. It tests a breathing exercise program to help improve lung function after surgery.
Giza, DokkiAges 13–17 - NCT07663292Recruiting
Exercise program to improve walking after stroke
This study tests whether a 12-week exercise program can help people who have had a stroke walk better. It focuses on those with a slower walking speed and uses brain scans to see if exercise can trigger positive changes in the brain.
Atlanta, GeorgiaAges 18–80 - NCT07660939RecruitingPhase 1
GPRC5D PET/CT scan for plasma cell disorders
This study uses a special PET/CT scan to look for a protein called GPRC5D in people with plasma cell disorders (like multiple myeloma). The scan might help doctors see where the disease is in the body. Healthy volunteers can also join to help compare results.
Beijing, Beijing MunicipalityAges 18–80 - NCT07659119Recruiting
Study of CT-FFR in chronic coronary syndrome patients
This study is following people with chronic coronary syndrome to see how a special CT-based blood flow test (CT-FFR) helps predict their heart health. If you have already had this test, you may be eligible to join and help doctors learn more about managing your condition.
Hangzhou, ZhejiangAges 18 years+ - NCT07662655RecruitingEarly Phase 1
PADN for pulmonary hypertension after mitral valve repair
This study tests a new procedure called pulmonary artery denervation (PADN) to lower high blood pressure in the lungs that persists after a mitral valve repair. It aims to see if this extra treatment improves symptoms and outcomes for people with this condition.
Xiamen, FujianAges 18–80 - NCT07655492Recruiting
Tailored brain training for Sturge-Weber syndrome
This study tests a personalized memory and thinking skills program designed for people with Sturge-Weber syndrome. It aims to see if this program can help improve daily life and brain function.
Roma, RomaAges 2 years+ - NCT07661849Recruiting
Comparing remote vs. in-person arm therapy after stroke
This trial compares two types of therapy—telehealth sessions at home versus in-person sessions—to help people recover arm and hand movement after a recent stroke. It aims to see if remote therapy works as well as coming to the clinic.
El Paso, TexasAges 21 years+ - NCT07655102Recruiting
Brugada Syndrome and Anesthesia: A Registry Study
This study is collecting information from people with Brugada syndrome who are having anesthesia or sedation for any procedure. The goal is to learn more about how these medications affect people with Brugada syndrome, so doctors can provide safer care in the future.
Barcelona, BarcelonaAges Any age - NCT07655206Recruiting
Home exercise for moderate to severe PAD
This study tests whether doing simple leg exercises at home with a small, portable pedal machine can help improve walking and blood flow in people with moderate-to-severe PAD. It's for people who cannot or prefer not to join a hospital-based exercise program.
Lévis, QuebecAges 18 years+ - NCT07660679Recruiting
Carotid ultrasound before liver transplant surgery
This study looks at whether measuring the thickness of the carotid artery (the main artery in the neck) before a planned liver transplant can help doctors predict and manage blood flow changes during surgery. It may help patients get safer care during their transplant.
DiyarbakırAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,610 recruiting cardiology studies from the U.S. registry right now, out of 14,650 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
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- Mental health
- Digestive system
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- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.