Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT03111459Recruiting
Endovascular repair for large thoracoabdominal aortic aneurysms
This trial studies a minimally invasive (endovascular) procedure to repair large or risky aneurysms in the aorta near the chest and abdomen. It may help prevent aneurysm rupture and improve outcomes compared with other possible treatments.
Cincinnati, OhioAges 18 years+ - NCT06486649Recruiting
AI tool for diagnosing HFpEF heart failure
This trial is testing a new AI-powered tool to help doctors better diagnose a specific type of heart failure called HFpEF, where the heart pumps normally but doesn't relax properly. It may help you if you have symptoms like shortness of breath or swelling and your heart ultrasound shows normal pumping ability.
Beijing, Beijing MunicipalityAges 18–80 - NCT06485661RecruitingEarly Phase 1
Captopril for heart health in Duchenne muscular dystrophy
This trial tests a heart medication called captopril in people with Duchenne muscular dystrophy who already have some early heart muscle changes. The goal is to see if it can help protect the heart.
CairoAges 6 years+ - NCT07462624Recruiting
Comparing treatments for a failing surgical aortic valve
This trial compares two ways to treat a failing aortic valve that was replaced with a tissue valve during surgery: another surgical replacement or a less invasive catheter-based valve-in-valve procedure. It is for people with low to intermediate surgical risk who are between 18 and 75 years old.
Leipzig, SaxonyAges 18–75 - NCT06473740RecruitingPhase 4
Gene therapy plus angioplasty for severe leg blockages
This study tests if adding gene therapy to a standard leg artery-opening procedure (angioplasty or stenting) helps people with severe leg pain or non-healing wounds due to blocked arteries. It may improve blood flow and save the leg from amputation.
Blagoveshchensk, Amur OblastAges 18 years+ - NCT07258602Enrolling by invitation
Understanding life with an ICD: A patient interview study
This study involves one-on-one interviews with people who have an ICD to understand their experiences and quality of life. If you have an ICD and speak Dutch, you may be able to share your story in a 30–60 minute conversation.
LeuvenAges 18 years+ - NCT06462989Enrolling by invitation
AI ECG for quick heart problem detection
This trial uses an AI tool called DeepECG to analyze ECG (heart electrical activity) recordings to quickly identify hidden heart problems. It helps doctors spot structural heart disease faster and guide you to the right care.
Montreal, QuebecAges 18 years+ - NCT07464574Recruiting
Lowering cholesterol with non-statin drugs
This study tests if adding non-statin medications can help people with heart or blood vessel disease who still have high cholesterol despite taking statins. It aims to get their LDL (bad) cholesterol to a safer level.
Austin, TexasAges 18 years+ - NCT05783804Recruiting
Early cholesterol-lowering to help reverse artery plaque
This trial studies whether starting strong cholesterol-lowering treatment early can reduce or reverse plaque in the arteries. It may help protect the heart over time, especially for people with inherited high cholesterol.
Amsterdam, North HollandAges 18–50 - NCT07465263RecruitingPhase 3
Study of SYH2053 Injection for High Cholesterol in HeFH
This study tests a new injection called SYH2053 for people with HeFH, a genetic condition that causes very high cholesterol. It looks at whether the injection can safely lower LDL cholesterol when added to standard statin therapy.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07362966RecruitingPhase 4
Colchicine for heart health after a heart attack
This study tests whether a low-dose medicine called colchicine can reduce inflammation and slow down artery blockages in people who have a specific gene change (TET2) and have recently had a heart attack. The goal is to see if it helps prevent future heart problems.
Shenyang, LiaoningAges 40–85 - NCT06414928Recruiting
Predicting Outcomes in Heart Failure Patients
This study is looking at people with heart failure who come to the emergency room at NICVD in Karachi. The researchers want to build a simple tool to predict how heart failure patients will do over the next 30 days, which may help guide better care.
Karachi, SindhAges 18 years+ - NCT06406842Recruiting
Brain oxygen and stroke risk in carotid surgery
This study looks at whether monitoring oxygen levels in the brain during carotid artery surgery can help predict or prevent a stroke. If you are having this surgery, researchers want to see if a simple monitor on your forehead can warn the surgical team of trouble.
Beijing, Beijing MunicipalityAges 18–80 - NCT06600347Recruiting
DASH diet and relaxation for heart health in menopause
This study tests whether a healthy eating plan (DASH diet) combined with a simple relaxation technique can lower heart risks in women after menopause. It may help you manage blood pressure and stress without medication.
SuezAges 50–60 - NCT06396767Recruiting
Breathing test before heart surgery to predict lung problems
This study uses a simple breathing test before scheduled heart surgery to see if it can help predict breathing or lung complications after the operation. The results may help doctors identify patients who need extra support during recovery.
London, OntarioAges 19–99 - NCT06565104Recruiting
Sleep study for people with high blood pressure
This study tests whether improving sleep can lower blood pressure. It is for people with elevated blood pressure or hypertension who speak English or Spanish.
New York, New YorkAges 20 years+ - NCT06314919Recruiting
Study of a combination pill for high cholesterol
This study tests a single pill that combines two cholesterol-lowering medicines (pitavastatin and ezetimibe). It may be a good fit if you already take a statin or a statin plus ezetimibe and your doctor wants to adjust your treatment.
SeoulAges 19 years+ - NCT06371170Recruiting
Rivaroxaban for heart clots in children
This study tests a blood thinner called rivaroxaban in children who have a blood clot inside the heart. The goal is to see if it safely and effectively dissolves the clot, potentially avoiding the need for stronger treatments.
Ancona, The MarchesAges 1 month–16 years - NCT06370611Enrolling by invitation
Home rehab after heart surgery for older adults
This study tests whether early, home-based rehabilitation (using video calls and remote monitoring) can help older adults recover better after heart surgery. If you join, you'll get rehab sessions starting soon after you go home.
AalborgAges 65 years+ - NCT06364150RecruitingPhase 3
Stem cell treatment for recent heart attack
This trial tests whether giving specially prepared stem cells from your own blood can help your heart recover after a heart attack. You must have had a successful angioplasty or stenting within the last 4 weeks.
SeoulAges 19–80 - NCT06353191Recruiting
Blood markers to predict heart problems from cancer therapy
This study looks for early warning signs (biomarkers) of heart damage caused by cancer treatments. It is for people who have had cancer treatment, may have heart issues, or are about to start a treatment that could affect the heart.
Scottsdale, ArizonaAges 18 years+ - NCT06352307Recruiting
Prevention and treatment strategies for arrhythmogenic cardiomyopathy
This trial evaluates early prevention and treatment strategies for arrhythmogenic cardiomyopathy (ACM), a heart condition that can cause abnormal heart rhythms. It aims to improve care by using advanced tests like heart imaging and genetic sequencing to guide treatment.
Xi'an, ShaanxiAges 18 years+ - NCT05334784Enrolling by invitation
Heart pump study for planned high-risk heart stent procedures
This study looks at using a temporary heart pump called Impella ECP during planned high-risk heart stent procedures (PCI). It may help doctors support the heart more safely while placing the stents.
Phoenix, ArizonaAges 18–90 - NCT06336083Recruiting
Study of carotid webs in families using ultrasound
This study looks at whether carotid webs (small flaps in the neck artery that can increase stroke risk) run in families. If you or a close relative has a carotid web, researchers will use a special ultrasound to check family members for the same condition.
ToulouseAges 18–65
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.