Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,981 recruiting studies in this area right now.
By phase
- Not applicable7,957
- Phase 2482
- Phase 4481
- Phase 3449
- Phase 1361
- Phase 1/Phase 2164
- Phase 2/Phase 387
Top conditions
- Stroke841
- Heart Failure566
- Hypertension400
- Cardiovascular Diseases389
- Coronary Artery Disease370
- Multiple Myeloma332
- Atrial Fibrillation267
- Ischemic Stroke201
- Atrial Fibrillation (AF)141
- Acute Ischemic Stroke138
- Myocardial Infarction100
- Pulmonary Hypertension100
- Congenital Heart Disease86
- Stroke, Ischemic85
- Peripheral Arterial Disease83
- Acute Coronary Syndrome82
- Obesity80
- Aortic Valve Stenosis79
Leading sponsors
- Mayo Clinic94
- Assistance Publique - Hôpitaux de Paris91
- National Taiwan University Hospital74
- China National Center for Cardiovascular Diseases59
- Beijing Tiantan Hospital52
- Riphah International University51
- Second Affiliated Hospital, School of Medicine, Zhejiang University51
- Massachusetts General Hospital50
- Insel Gruppe AG, University Hospital Bern49
- Johns Hopkins University47
Where studies are running
- California466
- Alabama197
- Massachusetts182
- Arizona173
- New York162
- Florida144
- Maryland120
- Minnesota120
- Illinois118
- Texas117
Recruiting studies9,978 total
- NCT07490184Recruiting
Heart check vs frailty score for hip surgery
This trial compares two ways to evaluate older adults before hip surgery to see which better predicts recovery. It may help doctors choose the safest approach for you.
Dallas, TexasAges 60 years+ - NCT06657833Recruiting
Drug Balloon vs Stent for Calcified Nodules After Shockwave
This trial tests whether a drug-coated balloon (a tiny balloon that releases medicine) works as well as a drug-coated stent (a mesh tube) for treating hard calcium deposits in heart arteries. Patients first receive a special shockwave treatment to break up the calcium.
LeidenAges 18 years+ - NCT05874843Recruiting
Testing a bedside blood clot test in children
This trial checks whether a bedside machine (TEG 6s) can measure blood clotting in children during planned surgery. It may help doctors get faster, more accurate information about clotting during the operation.
Indianapolis, IndianaAges 3 months–18 years - NCT06708338Recruiting
Bevel direction during dialysis fistula puncture
This study looks at which way the needle bevel should face when starting dialysis through a new fistula. It might help reduce pain or damage to the fistula.
Le Puy-en-VelayAges 18–85 - NCT06563895RecruitingPhase 3
Testing acoramidis to prevent ATTR amyloidosis in gene carriers
This trial tests a daily pill called acoramidis to see if it can prevent ATTR amyloidosis in people who carry a gene mutation but have no symptoms yet. It aims to stop the disease before it starts.
La Jolla, CaliforniaAges 18–75 - NCT06689878Recruiting
Mobile therapy for anxiety and depression after stroke
This study tests if a mobile cognitive behavioral therapy app can help reduce anxiety and depression in people who have had a stroke. If you are between 40 and 79 and have ongoing feelings of worry or low mood after your stroke, this therapy might be a convenient option.
New York, New YorkAges 40–79 - NCT07549893Recruiting
Coagulation of Middle Meningeal Artery During Brain Bleed Surgery
This trial tests a new technique during surgery for chronic subdural haematoma (bleeding between the brain and skull) where doctors use heat or special tools to seal a blood vessel (the middle meningeal artery) to help prevent the bleed from returning. The goal is to see if this addition to standard surgery is safe and feasible.
LondonAges 18 years+ - NCT07394998Recruiting
Exercise and Heart Health After Mitral Valve Treatment
This study looks at how well your heart and muscles work during exercise after a mitral valve procedure. It also checks stiffness of your main artery (aorta) and oxygen levels in your muscles.
Ankara, ÇankayaAges 18–80 - NCT06814990Recruiting
Heart and liver study for TIPSS patients
This study uses MRI and echocardiography to check heart function in people with alcohol-related liver cirrhosis who need a TIPSS procedure. It aims to learn more about how the heart works in these patients.
Jena, ThuringiaAges 18–99 - NCT07069738Recruiting
New pacemaker vs standard cardiac therapy for heart failure
This study tests a newer type of pacemaker that paces the heart's left bundle branch area, compared to the usual cardiac resynchronization therapy. It is for people with heart failure who need a combined pacemaker-defibrillator (CRT-D) and have a specific heart rhythm pattern (left bundle branch block) with reduced pumping strength.
Huntsville, AlabamaAges 18 years+ - NCT07111559RecruitingPhase 4
Comparing clot-busting drug versus two blood thinners for small stroke
This study tests whether a clot-busting drug (rt-PA) or a combination of two blood thinners (DAPT) works better for people having a small stroke caused by a blocked tiny artery in the brain. It aims to find the safest and most effective treatment within the first few hours after symptoms start.
ChūōAges 18 years+ - NCT07213479Recruiting
Exercise and lifestyle changes for high blood pressure
This trial tests whether isometric exercises (like wall sits or planks) and lifestyle changes can help manage high blood pressure. It's designed for people already on blood pressure medication who want to try a gentle exercise program.
Newcastle upon TyneAges 18 years+ - NCT07742215RecruitingPhase 3
Combination treatment for relapsed or refractory multiple myeloma
This trial tests a new drug (BCD-248) combined with daratumumab for people whose multiple myeloma has come back or stopped responding to previous treatments. The goal is to see if this combination can help control the cancer better.
HomyelAges 18 years+ - NCT07742020Recruiting
Movement therapy comparison for stroke recovery
This study compares two rehabilitation techniques to help people who have had a stroke regain movement in their arm or leg. It aims to find which method works better for improving daily function during the recovery phase.
Lahore, Punjab ProvinceAges 45–65 - NCT06465745Recruiting
AltaValve study for leaky mitral valve
This trial tests a new, less invasive device called the AltaValve to treat a leaky mitral valve. It is for people whose leak is severe enough to cause symptoms, but who cannot have standard surgery or a clip procedure.
Phoenix, ArizonaAges 18 years+ - NCT07742345Recruiting
Coronary support catheter for safer stent placement
This study tests a catheter that helps doctors guide stents and balloons through blocked heart arteries. It may make your procedure easier and safer if you need a stent placed.
BeijingAges 18 years+ - NCT07743021Recruiting
Blood sample study for better health screening
This study collects blood samples and health information over time to improve early detection of diseases. It may help researchers find ways to prevent serious conditions.
BalatonfüredAges 40 years+ - NCT01874197Recruiting
Studying branched stent grafts for complex aortic aneurysms
This trial tests a special stent graft to repair a thoracoabdominal aortic aneurysm (a bulge in the main artery in your chest and belly). It is for people whose aneurysm is too risky to treat with open surgery and who cannot use standard endovascular grafts.
Seattle, WashingtonAges 18 years+ - NCT07203404RecruitingEarly Phase 1
A study of a universal CAR-T cell therapy for autoimmune diseases
This trial tests a new treatment called RD06-05, which uses specially engineered immune cells to target and potentially reset parts of the immune system that are attacking your own body. It is being studied for several autoimmune conditions like lupus, vasculitis, kidney diseases, and more.
Shanghai, Shanghai MunicipalityAges 18–75 - NCT07742046Enrolling by invitation
Heart blood flow scan for congenital heart disease
This study tests a new MRI technique to measure blood flow in the heart without invasive procedures. It may help doctors better understand and manage congenital heart conditions.
LausanneAges 16 years+ - NCT07005232Enrolling by invitation
OmniaSecure defibrillation lead safety study
This study follows patients who have or will receive the OmniaSecure defibrillation lead to see how well it works and how reliable it is over time. If you have this lead, you may be able to help researchers understand its long-term performance.
Birmingham, AlabamaAges Any age - NCT04753970RecruitingPhase 1/Phase 2
Study uses retina changes to assess blood vessel health
This study looks at the back of your eyes (the retina) to see if it reflects blood vessel health in the brain. It may help doctors find easier ways to track conditions related to small blood vessel disease.
Jacksonville, FloridaAges 18 years+ - NCT06326996RecruitingEarly Phase 1
Thiamine before bypass surgery
This study tests if giving thiamine (vitamin B1) before heart bypass surgery can help people with low thiamine levels. It is designed for patients who are having a specific type of bypass that does not use a heart-lung machine.
Los Angeles, CaliforniaAges 60–80 - NCT07689760Enrolling by invitation
AI to Predict Hospital Readmission in Heart Failure
This study uses artificial intelligence (AI) to predict when people with heart failure might need to go back to the hospital. It's designed for patients who are already in a telemonitoring program and use an iPhone to track their health.
EnschedeAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,981 recruiting cardiology studies from the U.S. registry right now, out of 15,236 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.