Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT07625488Enrolling by invitation
Heart Disease Risk Follow-up Study for Former Athletes
This study follows up with people who participated in a heart-health study between 2012 and 2014. Researchers will use heart imaging and exercise tests to check your cardiovascular health and learn more about heart disease risk in athletes.
NijmegenAges 45 years+ - NCT07621367Recruiting
Gut oxygen therapy for bowel problems from low oxygen
This trial tests a treatment that delivers oxygen directly to the gut through a small tube. It is for people with long-term heart failure or sleep apnea who also have belly pain, bloating, constipation, or diarrhea.
Nanjing, JiangsuAges 18 years+ - NCT07624630Recruiting
Brain Activity and Walking After Stroke
This study examines how your brain works when you walk and think at the same time after stroke. Researchers will use brain imaging to understand this process, which could help develop better rehabilitation strategies.
Solna, Stockholm CountyAges 18 years+ - NCT07626710Recruiting
How Heart Valve Replacement Affects Kidney Function
This study looks at whether a minimally invasive heart valve procedure (TAVI) affects how well your kidneys work. Researchers will track your kidney function before and after the procedure using blood tests to understand any changes.
Roma, RMAges 18 years+ - NCT07622199Recruiting
Deep vein clot removal to improve blood flow in the thigh
This trial tests a procedure to remove blood clots from deep veins in the leg and pelvis. It aims to improve blood flow and reduce long-term leg damage. If you have a recent clot in these veins, you may be eligible.
ShanghaiAges 18–85 - NCT07621120Recruiting
Wearable Device to Predict Surgery Risk in Older Adults
This study uses a wristwatch-like device to measure your movement and body functions before and after surgery to help predict which older patients might have complications. The goal is to improve safety planning for people 65 and older having surgery.
Beijing, Beijing MunicipalityAges 65 years+ - NCT06652750Recruiting
5G cloud-based check-up for heart device patients
This study tests whether a 5G-based remote check-up (over the cloud) is safe and effective for people with certain implanted heart devices, like pacemakers. You'll skip your first clinic visit and instead use a video call or remote check to see how your device is doing.
Guangzhou, GuangdongAges 18 years+ - NCT03204357Recruiting
Using your own blood after heart-lung machine surgery
This trial studies giving a “fresh” blood transfusion from your own blood after heart surgery that uses a heart-lung machine. It may help patients avoid needing donated blood, but it only works for people who meet specific safety and timing requirements.
Aurora, ColoradoAges 18–90 - NCT04754022Recruiting
Blood use during heart surgery in younger adults
This study looks at how much donated blood (blood products) is needed for younger adults during heart surgery that uses a heart-lung machine. It may help doctors choose safer, more appropriate blood-saving plans for people like you.
Portland, MaineAges 18–65 - NCT04920253Recruiting
Testing a water-jet treatment to heal certain foot and leg wounds
This trial tests a new “micro water jet” device (Debritom+) to help heal specific hard-to-heal wounds in people who can attend frequent visits. If you qualify, you’ll be assigned to the device treatment or standard care and monitored to see how well the wound heals.
Bradenton, FloridaAges 18 years+ - NCT05460793Recruiting
Surgery timing trial for brain bleeding after a stroke
This trial looks at whether starting brain surgery within 8 hours after a type of stroke called intracerebral hemorrhage (bleeding in the brain) can improve outcomes. It’s for adults with a certain amount and location of bleeding and without common causes like an aneurysm or malformation.
AmsterdamAges 18 years+ - NCT05472207Recruiting
Risk check study for heart disease patients
This study looks at how to better sort people with heart disease into different risk groups. You may be asked for information about your heart condition and related health to help guide future care.
Innsbruck, TyrolAges 18 years+ - NCT06242366Recruiting
Transitional care program for stroke recovery
This trial tests a transitional care program for people recovering from a first-time stroke that caused weakness on one side of the body. The program is designed to help you manage your recovery at home after leaving the hospital.
Bang Kho Laem, BangkokAges 18 years+ - NCT06683157Recruiting
Study of calf vein clots with ultrasound monitoring
This study follows people with a blood clot in the calf vein to learn how the clot changes over time using repeat ultrasound scans. It may help doctors understand who needs treatment and who can be watched safely.
Dresden, SaxonyAges 18 years+ - NCT02856620Recruiting
Study heart function and frailty in people with aortic valve narrowing
This study looks at how heart mechanics, blood markers, and frailty relate to symptoms and heart measurements in people with aortic stenosis (a stiff, narrowed heart valve). It may help doctors better understand who is at higher risk and how disease changes over time.
Montreal, QuebecAges 18 years+ - NCT06699420RecruitingPhase 4
Qishenyiqi pill for small vessel heart disease
This trial tests if a Chinese herbal pill called Qishenyiqi can help people with chest pain caused by tiny heart blood vessels that are too tight. It may be an option if standard tests show your heart vessels are mostly clear but your blood flow is reduced.
Jinan, ShandongAges 40–75 - NCT06700005Recruiting
Reading study for stroke survivors and healthy adults
This study looks at how reading is affected by stroke and by normal aging. Researchers hope to learn how the brain changes after a stroke and during aging, which could help improve reading therapy for stroke survivors.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06698341Recruiting
Studying heart attacks in young adults to understand new genes
This trial looks for new genetic causes of heart attacks in young adults. If you had a heart attack at a young age and are of Chinese, Malay, or Indian descent, this study may help find answers.
SingaporeAges 21–60 - NCT06699446Recruiting
Seamless care from before to after heart surgery
This study is for people who are getting ready for heart surgery and want to follow a program that helps them prepare and recover. It tests a seamless approach from before surgery through rehabilitation, focusing on exercise and support.
Hanover, Lower SaxonyAges 18 years+ - NCT06700174Recruiting
AcuMark Balloon Study for Heart Hole Closure
This study uses a special balloon (AcuMark™ Sizing Balloon) to help doctors measure the exact size of a heart hole (atrial septal defect) before closing it. The goal is to make sure the closure device fits properly.
AnkaraAges Any age - NCT03720522Recruiting
Study brain-heart signals in acute stroke using MRI
This study looks at how the brain and heart interact right after an acute ischemic stroke. It may help doctors better understand what happens in the first hours of stroke and improve monitoring or future treatments.
Bern, Canton of BernAges 18–86 - NCT04441203Recruiting
Virtual clinic for managing heart failure at home
This trial tests a virtual “heart failure clinic” and home heart monitoring to help people manage symptoms and outcomes. It may help by catching problems earlier and guiding safer self-care between doctor visits.
Montreal, QuebecAges 18 years+ - NCT06698380Recruiting
Mirror therapy for arm recovery after stroke
This trial tests whether using a mirror to create the illusion of movement can help improve arm function in people who had a stroke more than six months ago. It may be a good option if you have limited arm movement and can follow simple instructions.
Riyadh, Riyadh RegionAges 45–65 - NCT04792281Recruiting
FDG-PET/CT scan to guide treatment for heart valve infection
This study tests whether an FDG-PET/CT scan (a special imaging test) can help doctors choose the best treatment plan for people with a suspected native heart valve infection. It may help reduce uncertainty by showing where the infection activity is.
Montreal, QuebecAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.