Cardiology
Heart & circulation clinical trials
Heart disease, blood pressure, and disorders of the blood vessels and circulation. We’re tracking 9,613 recruiting studies in this area right now.
By phase
- Not applicable7,634
- Phase 2471
- Phase 4471
- Phase 3438
- Phase 1350
- Phase 1/Phase 2161
- Phase 2/Phase 388
Top conditions
- Stroke796
- Heart Failure535
- Hypertension389
- Cardiovascular Diseases374
- Coronary Artery Disease362
- Multiple Myeloma328
- Atrial Fibrillation259
- Ischemic Stroke190
- Atrial Fibrillation (AF)154
- Acute Ischemic Stroke139
- Pulmonary Hypertension104
- Myocardial Infarction96
- Congenital Heart Disease83
- Peripheral Arterial Disease80
- Stroke, Ischemic77
- Aortic Valve Stenosis76
- Obesity74
- Acute Coronary Syndrome73
Leading sponsors
- Mayo Clinic93
- Assistance Publique - Hôpitaux de Paris88
- National Taiwan University Hospital67
- China National Center for Cardiovascular Diseases60
- Second Affiliated Hospital, Zhejiang University, School of Medicine58
- Beijing Tiantan Hospital53
- Insel Gruppe AG, University Hospital Bern49
- Massachusetts General Hospital49
- Yonsei University48
- Johns Hopkins University45
Where studies are running
- California449
- Alabama195
- Arizona182
- Massachusetts174
- New York166
- Florida141
- Texas122
- Maryland118
- Minnesota118
- Illinois111
Recruiting studies9,613 total
- NCT05760924Recruiting
Testing a new heart pacing method for CRT nonresponders
This trial tests whether a different pacing approach called left bundle branch pacing can improve outcomes and heart structure changes in people who did not improve with standard biventricular CRT. It may help some patients with ongoing heart failure symptoms and weak heart pumping.
TomskAges 18–80 - NCT06201598Recruiting
Treatment for brain aneurysms with flow-diverter stents
This study is testing if a type of stent called a flow-diverter is safe and effective for treating brain aneurysms. It may help patients who have an aneurysm that was found by chance, is causing symptoms, or has already ruptured.
A CoruñaAges 18 years+ - NCT06195267Recruiting
Sivelestat for lung protection during emergency aortic surgery
This study tests whether a drug called sivelestat can protect your lungs and other organs during emergency surgery for a very serious aortic tear. If you qualify, you would receive the drug or a placebo right before and after surgery.
BeijingAges 18–90 - NCT06523465RecruitingPhase 4
Statin plus amlodipine for primary aldosteronism
This trial tests whether combining a statin (usually for cholesterol) with amlodipine (a blood pressure medication) can better treat primary aldosteronism, a hormonal condition that causes high blood pressure. If you have this condition, this study may offer a new way to manage it.
Chongqing, Chongqing MunicipalityAges 18–70 - NCT06588413RecruitingPhase 3
Comparing two doses of olanzapine for nausea after stem cell transplant
This trial tests whether a lower dose of olanzapine (2.5 mg) works as well as the usual dose (5 mg) for preventing nausea and vomiting caused by high-dose melphalan chemotherapy. It is for people receiving their own stem cell transplant.
Augusta, GeorgiaAges 18 years+ - NCT06696469Recruiting
Virtual reality for arm recovery after stroke
This trial tests if a virtual reality system called BeCure can help people who had a stroke recover arm movement. It's for people who are still in the early to later stages of recovery (not the very first days) and have some movement and sitting balance.
AnkaraAges 18–80 - NCT06274697Recruiting
Testing a magnetic sensor for artery blood flow
This study tests a new magnetic sensor that measures blood flow in your arteries, comparing it to the standard method. It takes place in the heart-lung unit at Montpellier University Hospital, and aims to see if the sensor is accurate for people with or without leg artery disease.
MontpellierAges 18 years+ - NCT03497637Recruiting
Compare two ways to measure artery narrowing during heart procedures
This study compares two pressure-based methods (Vessel-FFR vs standard FFR) to decide how severe a heart artery narrowing is during a coronary angiogram or PCI. It may help patients and doctors choose which narrowings need treatment more accurately.
DresdenAges 18 years+ - NCT04372563Recruiting
Check treatment for aortic enlargement with tricuspid valve
This trial studies how to treat an enlarged part of the ascending aorta in people who have a tricuspid aortic valve. It may help slow or manage the risk connected to aorta enlargement.
TomskAges 45–75 - NCT06334003Recruiting
Heart health in moms and babies after fertility treatment
This study looks at how fertility treatments affect the heart and metabolism of mothers and their children. It compares women who became pregnant with or without fertility help to understand any differences.
CopenhagenAges 18–40 - NCT07613099RecruitingPhase 3
Testing a new PET scan to detect lung and heart scarring
This study tests a new imaging scan (called 18F-FAPI PET/CT) that may help detect scarring in the lungs, heart, or blood vessels. If you have a heart, lung, or blood vessel condition that could cause scarring, this scan might show damage earlier and help doctors plan better treatment.
Bethesda, MarylandAges 18–100 - NCT05725096Recruiting
CT scan helps guide cholesterol and heart risk care
This study is testing how a special heart scan (coronary CT angiography) can help manage cholesterol levels and other heart risk factors in people who feel well and have no known heart disease. It may help doctors better decide what lifestyle or medicines you may need to lower risk.
Nanjing, JiangsuAges 40–69 - NCT04882488Recruiting
Testing heart scan measurements in severe aortic valve narrowing
This trial compares two pressure-based measurements of blood flow in the coronary arteries with a PET heart scan in people with severe aortic valve stenosis. It may help doctors choose the most accurate way to assess blood flow and guide care during valve treatment.
Bad Oeynhausen, North Rhine-WestphaliaAges 65 years+ - NCT06697483Recruiting
Personalized maintenance therapy for multiple myeloma after stem cell transplant
This trial tests a personalized approach to maintenance therapy for people with multiple myeloma who have already had a stem cell transplant. Your treatment plan may be adjusted based on how well your cancer responds and on certain risk factors, with the goal of keeping you in remission longer.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06704230Recruiting
Video goggles to reduce stress during awake neck artery surgery
This trial tests if wearing video goggles during carotid artery surgery can help reduce stress. You would stay awake during the procedure and watch calming videos to see if it makes the experience less stressful.
Augsburg, BavariaAges 18 years+ - NCT07612774RecruitingPhase 4
Early cholesterol-lowering drug after heart attack study
This study tests whether starting evolocumab (a cholesterol-lowering injection) soon after a heart attack helps prevent future heart problems. You'll receive the study drug or placebo for 52 weeks while your heart is monitored with imaging scans.
Xi’an, ShanxiAges 40–75 - NCT07616622Enrolling by invitation
Recovery Methods for Upper Arm Weakness After Stroke
This study compares two physical therapy approaches—Roods (a sensory-based technique) and PNF (a stretching and strengthening method)—to help improve arm function in people recovering from their first stroke. Both methods aim to help you regain strength and control in your upper arm and hand.
Faisalābad, Punjab ProvinceAges 40–60 - NCT07620262Recruiting
Combined atrial fibrillation treatment and stroke prevention study
This study tests a new approach for people with atrial fibrillation (a type of irregular heartbeat) who are also at high risk for stroke. It combines a procedure to fix the heart's electrical signals with closing off a small pouch in the heart to reduce stroke risk, potentially avoiding long-term blood thinners.
Bay Shore, New YorkAges 18 years+ - NCT07614724Recruiting
How Your Body Responds to Salt in Diet
This study tests whether your blood pressure is sensitive to salt intake. Researchers will provide you with controlled meals for two weeks to see how your body responds, then invite qualifying participants to continue with a personalized follow-up study.
BeijingAges 20–65 - NCT07614906Recruiting
Nitric Oxide Levels to Predict Blood Vessel Spasms After Brain Bleeding
This study examines whether a substance called nitric oxide in brain fluid can help doctors predict who will develop dangerous blood vessel tightening after a subarachnoid hemorrhage—a serious type of brain bleeding. The goal is to find an early warning sign so doctors can intervene faster.
Boston, MassachusettsAges 18 years+ - NCT07613918Recruiting
Brain Blood Flow Monitoring in Critically Ill Children
This study measures how well blood flows to your child's brain while they're in the intensive care unit on a breathing machine. Understanding this flow may help doctors better care for critically ill children.
Madison, WisconsinAges 1 day–17 years - NCT07617376RecruitingPhase 4
Flu shot before leaving hospital after heart problems
This study tests whether giving a flu vaccine to patients before they leave the hospital after a heart condition improves their health. The vaccine may help protect your heart and prevent serious flu complications while you recover.
WroclawAges 18 years+ - NCT07613853Recruiting
Sharing heart disease risk information with patients
This study tests whether giving patients information about their heart disease risk through simple digital links helps them understand and act on their health. You're invited if you attended a recent Dallas Heart Study visit.
Dallas, TexasAges 35 years+ - NCT07619144Recruiting
Improving Heart Pump Outcomes Using Advanced Data Analysis
This study examines detailed data from patients who received an Impella 5.5 heart pump to treat cardiogenic shock—a life-threatening condition where the heart cannot pump enough blood. Researchers use advanced computer analysis to understand what helps patients recover best.
ViennaAges 18 years+
Common questions
- How many heart & circulation clinical trials are recruiting?
- Clin2 is tracking 9,613 recruiting cardiology studies from the U.S. registry right now, out of 14,690 we cover in this area in total.
- What does “Heart & circulation” cover here?
- Heart disease, blood pressure, and disorders of the blood vessels and circulation. We group each study into heart & circulation based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a heart & circulation trial near me?
- Use the search to filter heart & circulation studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Immune system & allergy
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- Skin
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- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
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- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.