Endocrinology & metabolism
Hormones & metabolism clinical trials
Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We’re tracking 7,616 recruiting studies in this area right now.
By phase
- Not applicable5,344
- Phase 2606
- Phase 1557
- Phase 3418
- Phase 4318
- Phase 1/Phase 2288
- Phase 2/Phase 385
Top conditions
- Obesity618
- Ovarian Cancer337
- Pancreatic Cancer287
- Type 2 Diabetes275
- Diabetes192
- Diabetes Mellitus182
- Diabetes Mellitus, Type 2171
- Hypertension138
- Type 1 Diabetes131
- Metabolic Syndrome127
- Obesity & Overweight125
- Breast Cancer111
- Cardiovascular Diseases105
- Overweight105
- Amyotrophic Lateral Sclerosis102
- Pancreas Cancer91
- Colorectal Cancer90
- Thyroid Cancer87
Leading sponsors
- Mayo Clinic87
- Novo Nordisk A/S64
- University of Colorado, Denver53
- Assistance Publique - Hôpitaux de Paris52
- M.D. Anderson Cancer Center42
- Eli Lilly and Company41
- Massachusetts General Hospital41
- IRCCS Azienda Ospedaliero-Universitaria di Bologna40
- National Taiwan University Hospital40
- Johns Hopkins University38
Where studies are running
- California521
- Maryland180
- Alabama176
- Arizona170
- Florida166
- Texas159
- Massachusetts150
- New York144
- Colorado115
- Pennsylvania113
Recruiting studies7,616 total
- NCT06638866Recruiting
AI screening for pancreatic cancer using regular CT scans
This trial uses artificial intelligence to analyze routine CT scans of the chest or abdomen (done for other reasons) to detect early signs of pancreatic cancer. If you are already getting a CT scan for another health issue, this could help catch pancreatic cancer early without extra tests.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06254261RecruitingPhase 2
RAY1225 for weight loss in obesity
This study tests an investigational medication called RAY1225 in people with obesity. It's given as an injection and may help with weight loss by targeting hormones that control appetite.
Beijingcun, HebeiAges 18–70 - NCT07282340RecruitingPhase 2
Phentermine for weight loss in teens
This study tests a medicine called phentermine to help teens ages 12 to 17 with obesity lose weight. It will check if the medicine is safe and works well for teenagers.
Wilmington, DelawareAges 12–17 - NCT06693934Recruiting
Prevention program for young adults at risk of diabetes
This trial offers a prevention program for young adults aged 18 to 44 who have at least one risk factor for diabetes but do not already have diabetes. The program aims to help prevent or delay the onset of diabetes.
Hong KongAges 18–44 - NCT07287748RecruitingPhase 1
Studying AF-001 for advanced thyroid cancer
This trial tests a new drug called AF-001 for people with thyroid cancer that has spread and can't be removed with surgery. It's for those who didn't benefit from or can't take standard treatments, or who haven't had radioactive iodine therapy yet.
KashiwaAges 18 years+ - NCT07287397RecruitingPhase 1/Phase 2
Testing VTx-002 for safety in ALS patients
This trial tests a new drug called VTx-002 to see if it is safe and tolerable for people with ALS. You may be able to join if you have had symptoms for less than 18 months and have a caregiver who can help.
Phoenix, ArizonaAges 18 years+ - NCT07285018RecruitingPhase 2
Study of a new drug for diabetic nerve pain in legs
This trial tests an investigational drug for people with pain caused by nerve damage from diabetes (diabetic peripheral neuropathy). It may help reduce pain in your lower legs if other treatments haven't worked well.
Birmingham, AlabamaAges 18 years+ - NCT07282600RecruitingPhase 3
Study of eloralintide for type 2 diabetes and weight
This study tests a new medicine called eloralintide for people with type 2 diabetes who are overweight or have obesity. It aims to see if the drug can help with weight loss and blood sugar control.
Birmingham, AlabamaAges 18 years+ - NCT07280221Enrolling by invitation
Wegovy real-world weight loss study in Korea
This study tracks how well Wegovy (a once-weekly injection for weight loss) works for people in Korea who are just starting the medication. It helps doctors understand real-world results outside of a research clinic.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT07287176Recruiting
Treating benign thyroid nodules with a new device
This trial tests a new device that uses nanosecond electrical pulses to treat benign thyroid nodules. It may be an option if you have a benign nodule causing symptoms like discomfort or anxiety, and you're looking for a non-surgical treatment.
Sarasota, FloridaAges 22–80 - NCT07286656RecruitingPhase 1
A study of GensSci098 for Graves' disease
This study tests a new investigational drug called GensSci098 for people with Graves' disease who have not taken antithyroid medication recently. It aims to see if the drug can help manage thyroid hormone levels.
Shenyang, LiaoningAges 18 years+ - NCT07286006Enrolling by invitationPhase 2
Long-term safety study of IMVT-1402 for Graves' disease
This study is a long-term extension for people with Graves' disease who already completed a previous study with the drug IMVT-1402. It aims to see how safe and effective the drug is over a longer period.
Phoenix, ArizonaAges 18 years+ - NCT07282613RecruitingPhase 3
CagriSema for blood sugar and weight in children with type 2 diabetes
This study tests a new medicine called CagriSema to see if it can lower blood sugar and help with weight loss in children and teens with type 2 diabetes. It compares the medicine to a placebo (a look-alike with no active drug) over several months.
New Haven, ConnecticutAges 10–18 - NCT07279194RecruitingPhase 3
Study of HDM1005 for weight loss in Chinese adults without diabetes
This trial tests a new medication, HDM1005, to help people with obesity or overweight who do not have diabetes lose weight. It is for Chinese adults who have a high body mass index (BMI) or a BMI above 24 with weight-related health problems like high blood pressure or fatty liver.
ShanghaiAges 18 years+ - NCT07282847RecruitingPhase 1/Phase 2
Gene therapy for adults with Pompe disease
This study tests a one-time gene therapy (AB-1009) for adults with late-onset Pompe disease. It aims to see if the treatment is safe and improves muscle and breathing function.
Phoenix, ArizonaAges 18–65 - NCT07280156RecruitingPhase 2
Study of PRX-115 for gout with or without methotrexate
This trial tests a new medicine, PRX-115, given through a vein, to see if it lowers uric acid levels in people with gout who haven't had success with standard treatments. Some participants will also take methotrexate, and the results are compared to a placebo (a dummy infusion).
Glendale, ArizonaAges 18 years+ - NCT07282743RecruitingPhase 2
Study of GL0034 for overweight or obese adults with type 2 diabetes
This trial tests a new medication, GL0034, to see if it helps with weight loss and blood sugar control in people with type 2 diabetes who are overweight. Participants must already be taking metformin and not using other diabetes drugs.
Little Rock, ArkansasAges 18 years+ - NCT06883578Recruiting
Effect of a low valine diet on body weight and metabolism
This trial studies if a diet low in valine, a building block of protein, can help people with excess weight lose weight and improve their metabolic health. It may offer an alternative approach for weight loss.
Shanghai, Shanghai MunicipalityAges 16–80 - NCT07283926Enrolling by invitation
Restorative meals at home for older adults on dialysis
This trial tests if providing supportive meals at home can improve nutrition and health for older adults (60+) with chronic kidney disease who are on hemodialysis and from low-income, food-insecure households in Malaysia.
Kuala Lumpur, Kuala LumpurAges 60 years+ - NCT07282639Recruiting
App-based diabetes education for type 1 diabetes
This study tests an app-based diabetes education program for people with type 1 diabetes. It aims to see if the app can help you manage your blood sugar levels better using insulin pens and a continuous glucose monitor.
Los Angeles, CaliforniaAges 18 years+ - NCT07285811Recruiting
Whey protein drink for blood sugar in older adults with type 2 diabetes
This study tests whether a whey protein drink can help improve blood sugar control in people aged 70-90 with type 2 diabetes. It involves 5 visits to a research center over a few weeks.
Birmingham, West MidlandsAges 70–90 - NCT07283887RecruitingPhase 4
Romosozumab and Denosumab for Postmenopausal Osteoporosis
This trial compares two osteoporosis drugs (romosozumab and denosumab) given alone or together to see which works better for improving bone density. It may help if you are a postmenopausal woman with osteoporosis and have not taken strong bone medications recently.
Douliu, TaiwanAges 50–80 - NCT07284277RecruitingPhase 1/Phase 2
TTFields and chemo for metastatic pancreatic cancer
This trial tests a wearable device (TTFields) combined with a specific chemotherapy (mFOLFIRINOX) for people whose pancreatic cancer has spread to the liver and other organs. The device sends gentle electrical fields to disrupt cancer cell growth, and the chemo attacks cancer cells throughout the body.
Pamplona, NavarreAges 18 years+ - NCT07283406Enrolling by invitation
High-intensity interval training for young adults with obesity
This study tests whether high-intensity interval training (short bursts of intense exercise) can improve heart health and fitness in young adults with obesity. You would participate in a supervised exercise program to see if it helps lower your risk of future health problems.
Guadalajara, JaliscoAges 18–35
Common questions
- How many hormones & metabolism clinical trials are recruiting?
- Clin2 is tracking 7,616 recruiting endocrinology & metabolism studies from the U.S. registry right now, out of 11,939 we cover in this area in total.
- What does “Hormones & metabolism” cover here?
- Diabetes, obesity, thyroid, and other conditions of the body’s hormones and metabolism. We group each study into hormones & metabolism based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a hormones & metabolism trial near me?
- Use the search to filter hormones & metabolism studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.