Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT05157282Recruiting
Spinal cord stimulation to improve hand function after tetraplegia
This trial tests whether a special device that stimulates the spinal cord can help people with long-lasting neck spinal cord injuries recover useful hand movement and grip strength. It may help your nervous system communicate better so daily hand tasks become easier.
Chicago, IllinoisAges 18–70 - NCT05170815Recruiting
Spine Device Registry for Adults Getting Commercial Devices
This study is a registry that collects information about adults who use specific, commercially available spine devices. It may help doctors understand how these devices are used in real-world care and what outcomes look like over time.
LyonAges 18 years+ - NCT05156749Recruiting
Short vs long casts for certain forearm fractures in kids
This study compares short-arm versus long-arm fiberglass casts to see which one works best for healing certain forearm bone injuries in children. It may help families choose a cast type that supports proper healing while aiming for comfort and safe recovery.
ZurichAges 4–16 - NCT05157126RecruitingPhase 4
Gentamicin antibiotic study for open tibia fractures
This trial tests whether a gentamicin antibiotic approach helps heal certain open tibia (shin bone) fractures while lowering infection risk. It focuses on adults with specific types of open, mostly closable tibia wounds treated within set time limits.
Dar es SalaamAges 18 years+ - NCT05163639RecruitingEarly Phase 1
Noninvasive brain and spinal training for spinal cord injury
This early study tests a noninvasive way of training the nervous system to see how it affects “associative plasticity,” or the brain/spinal cord’s ability to change with practice. It may help researchers learn strategies that could improve function for people with spinal cord injury.
New York, New YorkAges 18–80 - NCT05163899Recruiting
Surgery to release an occult tethered cord
This trial studies whether a specific back surgery (cutting/releasing part of the filum terminale) helps people with an “occult” tethered cord syndrome when symptoms have not improved with medicine. It may help by reducing traction on the spinal cord to improve bladder/bowel, skin, or nerve-related symptoms.
New York, New YorkAges 2–80 - NCT05178056Recruiting
Spinal cord stimulator to improve breathing after spinal injury
This study looks at whether a spinal cord stimulator can improve breathing and lung function in adults with a certain type of spinal cord injury. It may help people who have ongoing breathing weakness after their injury.
Louisville, KentuckyAges 18 years+ - NCT05183152Recruiting
Non-invasive brain signal control for assistive devices
This study tests an assistive device that you control using signals from the brain and muscles without surgery. It may help people with movement problems communicate or operate devices using gentle, non-invasive sensing.
Austin, TexasAges 18–80 - NCT05142943Recruiting
Virtual reality to improve arm function after spinal cord injury
This study tests whether a virtual reality program that creates a feeling of body ownership can help improve arm and hand movement in people who have an incomplete spinal cord injury in the neck. It aims to find a new, engaging way to boost recovery.
Valencia, ValenciaAges 18–99 - NCT05111925Recruiting
Testing after-injury and after-recovery readiness for full duty
This study looks at how well service members are able to return to full physical duty after a low-back or leg injury (or to see readiness in those without an injury). It may help improve return-to-duty planning by measuring changes before and after recovery.
Bethesda, MarylandAges 18–44 - NCT05122728Recruiting
Tracking injury risk after concussion and body movement changes
This study looks at how being recently concussion-affected changes musculoskeletal (muscle/joint) injury risk and recovery during physical activity. It compares a group who is currently recovering after concussion with a similar healthy group to better understand risk factors over time.
Athens, GeorgiaAges 18–40 - NCT05091645Recruiting
Testing a Greek version of a frailty screening for hip fracture patients
This trial checks whether a translated and culturally adapted questionnaire (called the Groningen Frailty Indicator) works well for people age 65+ who have a hip fracture and are having surgery. It may help care teams better understand frailty and plan support after surgery.
LarissaAges 65 years+ - NCT05112302Enrolling by invitation
Virtual reality during orthopedic anesthesia
This study tests whether using virtual reality during hip or knee surgery (while you’re receiving a nerve block for anesthesia) helps make the experience more comfortable. You’d try the VR during your procedure, and the team will compare outcomes with usual care.
Jackson, FloridaAges 18 years+ - NCT05124652Recruiting
Testing a prosthetic socket that adjusts automatically
This trial is testing a prosthetic socket that can automatically adjust to help fit better and feel more comfortable. It may help people with below-knee (transtibial) amputations who currently struggle with socket fit or comfort.
Seattle, WashingtonAges 18 years+ - NCT05131321Recruiting
Testing a frailty-focused plan for serious ankle fractures
This trial studies how best to manage serious ankle or tibia-pilon fractures in older adults who may be frail or have other major health problems. The goal is to improve care decisions and outcomes after injury, especially in people more likely to have complications.
London, OntarioAges 40 years+ - NCT05134311Recruiting
3D ultrasound check for blood-flow problems in wound care
This study tests whether a 3D ultrasound scan can better assess blood-flow problems that may affect healing in the wound clinic. If you’re already scheduled for an ultrasound evaluation at the wound center, the trial may use an additional 3D ultrasound approach to help doctors understand your circulation.
Lake Success, New YorkAges 18 years+ - NCT05094362Recruiting
Training to reduce stiff leg reflexes after spinal cord injury
This study tests a special training approach designed to calm overactive leg reflexes (spasticity) after spinal cord injury. If you qualify, you may do structured walking/reflex training to see whether your leg reflexes and movement improve.
Charleston, South CarolinaAges 18 years+ - NCT05095909Recruiting
Frozen compression at intervals vs regular icing after shoulder surgery
This trial tests whether using a special device that gives cold in pulses (intermittent cryo-compression) helps the shoulder feel better after arthroscopic rotator cuff repair compared with traditional icing. It may help with pain and recovery during the early healing period after surgery.
Plymouth, MinnesotaAges 18–70 - NCT05073276Recruiting
Controlled weight-bearing after PCL or MCL knee ligament repair
This trial tests a specific, step-by-step approach to how much weight you put on your healing knee after surgery for certain ligament injuries (like PCL and/or MCL, and some combined cases). It may help you heal safely and recover function without putting too much strain on the repair.
Edina, MinnesotaAges 14–59 - NCT05131672Recruiting
Casting vs surgery for elbow bone fractures in children
This study compares two treatments—casting or an operation—for a specific elbow fracture in children. It aims to see which approach works best for healing and recovery after a recent fracture.
Chicago, IllinoisAges 7–17 - NCT05110937Recruiting
Testing immune cell changes in sepsis and trauma shock
This study looks at abnormal immune cells (from the bone marrow) in people with sepsis or severe trauma with shock. It aims to understand why the body’s immune response gets out of balance, which could help guide future treatments.
Gainesville, FloridaAges 18–100 - NCT05122325Enrolling by invitation
Treatment to improve sexual function after spinal cord injury
This trial looks for a treatment that can improve sexual problems in women whose spinal cord injury has partially affected sensation and function. You may be able to join if you are not in menopause and your sexual difficulty started after your injury and has lasted at least 12 months.
Toledo, ToledoAges 18–60 - NCT05073263Recruiting
Full versus partial weight bearing after FCL ligament repair
This study compares two rehab plans: doing full weight bearing versus partial weight bearing during the first 6 weeks after fibular collateral ligament (FCL) reconstruction. It may help figure out which approach is safer and better for healing and recovery.
Edina, MinnesotaAges 14–59 - NCT05131685Recruiting
Child wrist fracture study comparing treatment for certain breaks
This study looks at treatment for children’s wrist (distal radius) fractures that are very displaced but not involving the growth plate. It may help doctors find the best way to reset and stabilize the bone when the fracture is recent.
Phoenix, ArizonaAges 4–10
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.