Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,016 recruiting studies in this area right now.
By phase
- Not applicable2,561
- Phase 2123
- Phase 4112
- Phase 382
- Phase 182
- Phase 1/Phase 234
- Phase 2/Phase 322
Top conditions
- Traumatic Brain Injury151
- Spinal Cord Injuries142
- Spinal Cord Injury105
- Stroke64
- Trauma51
- Mild Traumatic Brain Injury40
- Amputation38
- Anterior Cruciate Ligament Injuries37
- Radiotherapy Side Effect37
- Hip Fractures36
- Rotator Cuff Tears35
- Spinal Cord Injuries (SCI)34
- Burns28
- Carpal Tunnel Syndrome28
- Anterior Cruciate Ligament Rupture27
- Cardiotoxicity26
- Carpal Tunnel Syndrome (CTS)26
- Breast Cancer25
Leading sponsors
- VA Office of Research and Development34
- Cairo University22
- Kessler Foundation20
- Johns Hopkins University19
- University of Miami19
- Zimmer Biomet19
- University of Florida18
- University of British Columbia17
- Mayo Clinic16
- Riphah International University16
Where studies are running
- California159
- Texas91
- Florida79
- New York78
- Illinois57
- Massachusetts55
- Pennsylvania51
- Minnesota45
- Ohio43
- Colorado41
Recruiting studies3,016 total
- NCT04323410Recruiting
Compare two ways to fix children’s forearm bone fractures
This study compares two surgical methods—casting versus percutaneous pinning—to treat certain distal (near the wrist) forearm fractures in children. It aims to find which method works best for healing and function, especially in specific fracture types.
HelsinkiAges Up to 10 years - NCT04269447Enrolling by invitation
Collecting samples from people with abdominal aortic aneurysm
This study sets up a long-term biobank by collecting health information and tissue/blood samples from people with an abdominal aortic aneurysm. It may help doctors better understand what causes aneurysms and how to detect or treat them in the future.
Solna, Stockholm CountyAges 50–80 - NCT04263285Recruiting
Repetitive brain stimulation for depression after spinal cord injury
This trial studies a brain-stimulation treatment to improve depression symptoms in people who have depression after a spinal cord injury. It may help if you have major depression and meet specific safety and eligibility checks.
Charleston, South CarolinaAges 18–70 - NCT04344119Recruiting
Study of chilblains during COVID-19 infection
This study looks at skin lesions (chilblains) that appear in people with a confirmed COVID-19 infection. It aims to better understand these skin changes.
NiceAges Up to 90 years - NCT04349852Recruiting
Memory and attention training for adults after brain injury
This trial tests a therapy that helps improve verbal working memory and attention in adults who had a traumatic brain injury (TBI). It may help by training thinking skills that are often affected after an injury, but it’s only for people who meet timing and mental health substance-use requirements.
New York, New YorkAges 18 years+ - NCT04296071Recruiting
Testing blood markers after heart surgery in infants
This trial studies patterns in immune cells (neutrophils) in very young children who undergo heart surgery using a heart-lung machine. The goal is to better understand and potentially reduce lung injury after surgery.
Boston, MassachusettsAges Up to 1 year - NCT04265430RecruitingPhase 4
MRI scans to predict normal-tissue side effects after treatment
This trial uses repeated MRI scans to better predict which patients may develop painful jaw and mouth tissue problems after radiation and/or certain bone or blood-vessel medicines. It may help clinicians spot problems earlier and tailor follow-up care.
Houston, TexasAges 18 years+ - NCT03042988Recruiting
Heat stress test in people with low nerve control and high blood pressure
This study checks how your body’s blood pressure and stress responses change after being exposed to heat overnight. It’s meant for people with autonomic failure (like certain Parkinson-related or nerve-function conditions) who also have high blood pressure while lying down, which may help researchers understand safer ways to manage it.
Nashville, TennesseeAges 18–80 - NCT04193475Recruiting
Uses computer learning to improve stress heart ultrasound
This study uses computer technology (“machine learning”) with stress echocardiogram images (a heart ultrasound done during stress) to improve how heart function is measured. If you are able to have a stress echocardiogram, you may be able to help test a better way to interpret the results.
CottinghamAges 20–89 - NCT04183803Recruiting
Robot help to set the right position for ACL surgery
This study tests whether using a robot to help place the tunnel during ACL (knee ligament) reconstruction is better or more accurate than the usual approach. You may benefit if you need ACL surgery and your care team has robot experience.
AmiensAges 10 years+ - NCT04206215Recruiting
Noninvasive brain stimulation for carpal tunnel pain relief
This study tests whether a noninvasive brain stimulation treatment can reduce chronic carpal tunnel (CTS) pain, especially when pain spreads beyond the usual nerve area. If you have long-lasting CTS pain that hasn’t improved with standard treatments, you may be able to try this therapy while being closely monitored for safety.
Charlestown, MassachusettsAges 18–80 - NCT04201704Recruiting
Less IV fluids for children after trauma
This trial studies whether giving children less fluid through a vein after serious injury helps them recover safely. Children are enrolled soon after arrival to the ICU so the team can compare outcomes between different fluid amounts.
Buffalo, New YorkAges 6 months–15 years - NCT04198454Enrolling by invitation
Compression and CO2 laser for lower leg wounds
This study looks at whether using leg compression and a CO2 laser after lower-leg wound surgery helps wounds heal better. You may be a candidate if you have a sizeable lower-leg wound that will be treated with a specific type of surgical healing plan.
Chicago, IllinoisAges 18 years+ - NCT04221542RecruitingPhase 1
AMG 509 for advanced, hormone-resistant prostate cancer
This trial tests AMG 509, a study drug, in men with metastatic castration-resistant prostate cancer (cancer that keeps growing despite lowering testosterone). It’s for people whose cancer has progressed after certain hormone tablets and possibly chemotherapy, aiming to shrink tumors and control the disease safely.
Duarte, CaliforniaAges 18 years+ - NCT03965299Recruiting
Gentle nerve stimulation for new spinal cord injury recovery
This study tests whether stimulation through the skin of the tibial nerve can help people with a new spinal cord injury. It may help improve bladder-related symptoms or nerve signaling after injury, compared with standard care.
Zurich, Canton of ZurichAges 18 years+ - NCT04124029Recruiting
How head injuries affect brain health
This study looks at how mild or moderate head injuries (concussions) may relate to brain conditions like chronic traumatic encephalopathy (CTE) and Alzheimer's disease. By comparing people with and without head injuries, researchers hope to learn more about what causes brain changes over time.
Boston, MassachusettsAges 30–90 - NCT04043442Enrolling by invitationPhase 2
Brain stimulation study for alcohol use with mild brain injury
This trial tests a type of brain stimulation to help with day-to-day functioning in people who have alcohol use disorder and a history of mild traumatic brain injury. It also uses brain and symptom testing to see who may benefit most and why.
Hines, IllinoisAges 22–65 - NCT04028687Recruiting
Study of a hip stem used in select adult hip replacements
This trial follows people who have had a hip replacement using a specific “Taperloc Complete” stem. It is meant to monitor outcomes after surgery and see how well the stem performs over time for certain non-infectious hip problems.
Henderson, NevadaAges 18 years+ - NCT04076735Recruiting
Compare fixing vs replacing certain leg bone fractures in seniors
This trial studies which operation works better for an acute distal femur (upper knee area) fracture in older adults: repairing/fixing it versus replacing the joint/bone. It may help find the safest approach and improve walking and recovery for people in this situation.
Toronto, OntarioAges 65 years+ - NCT04075305Recruiting
Study measuring radiation treatment outcomes with an MR-Linac
This study follows what happens when radiation treatment is guided using an MR-Linac (a special machine that combines MRI imaging with radiation). It may help improve how radiation therapy is planned and assessed, especially for people who can safely have MRI scans.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04117672RecruitingPhase 2
Test antisecretory treatment in severe brain injury
This Phase 2 study tests an “antisecretory factor” treatment in people with severe traumatic brain injury. It may help by improving harmful processes after injury, but your eligibility depends on specific brain-injury severity and monitoring needs.
LundAges 10–70 - NCT04144972Recruiting
Closed-loop deep brain stimulation for long-lasting nerve pain
This trial tests a “smart” deep brain stimulation device that senses your brain signals and adjusts treatment to reduce severe, long-lasting pain. It may help people whose pain has not improved with multiple pain medicines and surgery cannot fix the cause.
San Francisco, CaliforniaAges 22–80 - NCT04032990Enrolling by invitation
Testing a skin-based nerve stimulation for kids’ arm function
This trial studies whether a painless, skin-based treatment (stimulation over the spine) is safe and feasible to improve arm and hand function in children with a spinal cord injury. It’s mainly designed to see if the approach can be done safely and whether it may help upper-limb skills.
Louisville, KentuckyAges 4–18 - NCT04095598Recruiting
CT scan with stress tests for unstable ankle ligaments
This study tests whether a special CT scan with gentle stress maneuvers can better find ankle ligament injury (syndesmotic instability) after a sprain. If you had a recent ankle sprain and exam suggests this specific injury, the scan may help guide the right treatment.
São Paulo, São PauloAges 18 years+
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,016 recruiting trauma studies from the U.S. registry right now, out of 4,936 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.