Trauma
Injuries & trauma clinical trials
Wounds, fractures, and recovery from physical injury. We’re tracking 3,219 recruiting studies in this area right now.
By phase
- Not applicable2,751
- Phase 2121
- Phase 4117
- Phase 187
- Phase 384
- Phase 1/Phase 237
- Phase 2/Phase 322
Top conditions
- Spinal Cord Injuries153
- Traumatic Brain Injury150
- Spinal Cord Injury100
- Trauma60
- Stroke56
- Anterior Cruciate Ligament Injuries44
- Amputation43
- Mild Traumatic Brain Injury41
- Hip Fractures40
- Rotator Cuff Tears40
- Radiotherapy Side Effect36
- Spinal Cord Injuries (SCI)35
- Carpal Tunnel Syndrome34
- Burns31
- Anterior Cruciate Ligament Rupture30
- Breast Cancer29
- Cardiotoxicity29
- Carpal Tunnel Syndrome (CTS)25
Leading sponsors
- VA Office of Research and Development37
- Cairo University36
- Riphah International University32
- Kessler Foundation21
- University of Miami21
- Johns Hopkins University20
- Sohag University19
- Mayo Clinic18
- Peking University Third Hospital18
- University of Texas Southwestern Medical Center18
Where studies are running
- California167
- Texas101
- New York85
- Florida80
- Illinois57
- Massachusetts57
- Pennsylvania52
- Ohio51
- Minnesota46
- Maryland42
Recruiting studies3,219 total
- NCT06857448Recruiting
Fat grafting for recent wounds and burns
This trial tests whether using your own fat cells can help heal wounds or burns that need surgery. It is for adults who have had a fasciotomy, full-thickness skin loss, or burns, and are willing to receive a fat graft.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT06921707Recruiting
WounDx test for healing decisions in large wounds
This trial tests a new tool called WounDx that helps doctors decide the best way to treat large wounds on arms, legs, or buttocks. It may help your wound heal better by guiding your care.
Birmingham, AlabamaAges 18–65 - NCT07718321Recruiting
StimolIrpinia for brain injury rehab: a feasibility trial
This trial tests a new cognitive rehab tool called StimolIrpinia for people recovering from a serious brain injury. It aims to see if the tool is acceptable and helpful for improving thinking and memory.
Sant'Angelo dei Lombardi, AVAges 18–75 - NCT07715864RecruitingPhase 2
Cannabis compounds for brain protection after concussion
This trial tests whether natural cannabis compounds can help protect the brain after a concussion in male contact-sport athletes. It requires you to be healthy, not a regular cannabis user, and free of certain medical conditions.
Regina, SaskatchewanAges 19–35 - NCT07716787Recruiting
Brain monitoring during breathing therapy in critically ill patients
This study looks at how a breathing machine setting (called PEEP) affects blood flow in the brain. If you or your loved one is in the ICU with a serious brain injury and is on a breathing machine, this trial could help doctors understand how to make breathing therapy safer for the brain.
Dongying, ShandongAges 18 years+ - NCT07280351Enrolling by invitation
Duraplasty for acute spinal cord injury
This trial tests whether adding a special patch (duroplasty) during emergency spinal surgery helps people recover from a recent traumatic spinal cord injury. It's for patients who need decompression surgery within 24 hours of injury.
San Francisco, CaliforniaAges 18–80 - NCT06025253Recruiting
Negative pressure dressing after leg amputation
This trial tests a special wound dressing that applies gentle suction to the incision after major leg amputation. It aims to reduce wound complications and help the stump heal better.
Dublin, DublinAges 18 years+ - NCT06868316Recruiting
Sound-guided walking training for chronic ankle instability
This study tests whether using sound cues while walking can improve balance and ankle stability in people with chronic ankle instability. You may be eligible if you have had repeated ankle sprains and a feeling of your ankle "giving way" in the last 6 months.
Lexington, KentuckyAges 18–45 - NCT06907849Enrolling by invitationPhase 2
Imaging amyloid in spinal stenosis and carpal tunnel
This trial tests a special scan that uses a radioactive tracer to look for amyloid protein deposits in people who have had surgery for lumbar spinal stenosis (narrowing of the spine in the lower back) or carpal tunnel syndrome. The goal is to see if the scan can detect these deposits, which may be linked to ongoing orthopedic issues.
Knoxville, TennesseeAges 60 years+ - NCT06952257Enrolling by invitation
Anesthesia type and safety in hip fracture surgery
This study is comparing different types of anesthesia (general vs. spinal/epidural) during hip fracture surgery to see which one is safer and reduces the risk of a rare but serious reaction called bone cement implantation syndrome. It may help you if you are scheduled for a cemented partial hip replacement.
Baltimore, MarylandAges 18 years+ - NCT07484516Recruiting
Eccentric exercises and muscle energy for tennis elbow
This trial tests whether combining eccentric exercises with muscle energy technique can help reduce pain and improve function in people with tennis elbow. It is for those who have had symptoms for more than a few weeks.
Karachi, SindhAges 20–50 - NCT07715656Recruiting
Middle-meningeal-artery embolization for chronic subdural hematoma
This trial studies a procedure called middle-meningeal-artery embolization, which blocks the blood supply to a chronic subdural hematoma (a slow-growing blood collection around the brain). It compares outcomes in people with one-sided versus both-sided bleeds, and aims to see if this less invasive treatment can help reduce the need for surgery or improve recovery.
Burlington, MassachusettsAges 18 years+ - NCT07714811Recruiting
Hyaluronic acid vs PRP for chronic tendon pain
This study compares two treatments—hyaluronic acid (a natural lubricant) and platelet-rich plasma (PRP, made from your own blood)—for chronic tendon pain. You may be a good fit if you have had pain in your Achilles tendon or golfer's elbow for more than 3 months and are looking for a non-surgical option.
Lublin, Lublin VoivodeshipAges 18–65 - NCT04437498Recruiting
Vagus nerve stimulation for veterans with mild brain injury and PTSD
This study looks at whether stimulating the vagus nerve can improve symptoms in veterans who have mild traumatic brain injury (mTBI) and post-traumatic stress disorder (PTSD). If you qualify, you may be offered a device-based treatment and monitored for safety and symptom changes.
Decatur, GeorgiaAges 18–55 - NCT07712198Recruiting
AI predicts muscle loss risk in brain injury ICU patients
This study uses artificial intelligence to predict which brain injury patients in the intensive care unit are at risk for muscle loss (sarcopenia). It aims to help doctors identify and prevent this complication early.
TrabzonAges 18–65 - NCT06928116Recruiting
Heat therapy and mobility for COVID-19 survivors
This study tests whether heat therapy (like using a heated blanket or suit) can help people who still feel tired or weak months after COVID-19. It may improve your physical function and make daily activities easier.
Omaha, NebraskaAges 50–90 - NCT06595914Enrolling by invitation
Improving education for mild traumatic brain injury
This trial is working to improve how doctors and nurses teach patients about mild traumatic brain injury (mTBI) in the emergency room and after they go home. It may help you get clearer information and support during recovery.
Milwaukee, WisconsinAges 18 years+ - NCT06465290Recruiting
Brain recovery treatment for recent stroke with ankle stiffness
This trial tests a treatment to help your brain recover after a stroke. It focuses on improving ankle movement and leg strength using exercises that promote brain rewiring.
Baltimore, MarylandAges 30–85 - NCT07706296Recruiting
Hand function tests for carpal tunnel syndrome
This study tests whether certain hand function tests are reliable and accurate for people with carpal tunnel syndrome. It helps doctors better understand how the condition affects your hand use.
IzmirAges 18–60 - NCT06452485Recruiting
Re-irradiation with or without hyperthermia, or surgery only for recurrent breast cancer
This trial compares three treatment options for breast cancer that has come back in the chest or lymph nodes after previous radiation. It looks at adding hyperthermia (heating the tumor area) to re-irradiation, versus just re-irradiation or surgery alone, to see which offers better quality of life and survival with fewer side effects.
AmsterdamAges 18 years+ - NCT05933629Recruiting
Training mental health providers to deliver an online TBI group program
This study helps test whether community mental health clinicians can learn and successfully deliver an online emotion-regulation group program for people with traumatic brain injury (TBI). It may help improve access to structured support when in-person group care is hard to reach.
New York, New YorkAges 18 years+ - NCT05951777RecruitingPhase 2
Stem cells from your own fat for chronic brain injury
This trial tests whether stem cells taken from your own fat and given through an IV can help people with long-term brain damage from a head injury. It is for adults who have not gotten better with standard treatments.
Houston, TexasAges 18–55 - NCT07706452Recruiting
Balance Training for People with a Prosthetic Leg
This study tests a special balance training program for people who use a prosthetic leg after losing a leg due to injury. The program combines balance exercises with a second task (like talking or counting) to improve walking and stability in daily life.
Gaza, Gaza StripAges 18 years+ - NCT06924177Recruiting
Spinal cord injury diet study for wheelchair users
This study tests a special diet program for people with spinal cord injuries who use a wheelchair. It aims to see if the diet can improve health and well-being.
Dallas, TexasAges 18–65
Common questions
- How many injuries & trauma clinical trials are recruiting?
- Clin2 is tracking 3,219 recruiting trauma studies from the U.S. registry right now, out of 5,138 we cover in this area in total.
- What does “Injuries & trauma” cover here?
- Wounds, fractures, and recovery from physical injury. We group each study into injuries & trauma based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a injuries & trauma trial near me?
- Use the search to filter injuries & trauma studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.