Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,637 recruiting studies in this area right now.
By phase
- Not applicable4,308
- Phase 2850
- Phase 1471
- Phase 3425
- Phase 1/Phase 2309
- Phase 4208
- Phase 2/Phase 366
Top conditions
- Lung Cancer424
- Asthma194
- Non Small Cell Lung Cancer189
- Non-Small Cell Lung Cancer181
- Non-small Cell Lung Cancer172
- Obstructive Sleep Apnea155
- COPD143
- Breast Cancer110
- COVID-19107
- Pulmonary Hypertension100
- NSCLC95
- Chronic Obstructive Pulmonary Disease90
- Colorectal Cancer84
- Pneumonia79
- Cystic Fibrosis78
- Interstitial Lung Disease78
- Acute Respiratory Distress Syndrome72
- Chronic Obstructive Pulmonary Disease (COPD)72
Leading sponsors
- Assistance Publique - Hôpitaux de Paris79
- AstraZeneca65
- Mayo Clinic53
- M.D. Anderson Cancer Center46
- National Cancer Institute (NCI)39
- VA Office of Research and Development39
- Chinese University of Hong Kong36
- Shanghai Chest Hospital36
- University Health Network, Toronto36
- Memorial Sloan Kettering Cancer Center34
Where studies are running
- California393
- Alabama173
- Arizona156
- Massachusetts128
- Florida116
- New York113
- Maryland111
- Texas90
- Pennsylvania83
- Illinois72
Recruiting studies6,637 total
- NCT06135909Recruiting
CHASE registry for pulmonary hypertension patients on treatment
This study is a registry that collects information on people with pulmonary hypertension who are using or starting targeted medications. The goal is to understand how these treatments work in real-world settings and improve care for patients like you.
BeijingAges 18–85 - NCT06137040RecruitingEarly Phase 1
Early IV Magnesium for Moderate Asthma in Children
This trial tests whether giving magnesium sulfate through an IV early in the emergency room helps children aged 5–17 who are having a moderate asthma attack. It aims to improve breathing and reduce the need for hospital stays.
Oklahoma City, OklahomaAges 5–17 - NCT06137196Recruiting
Lung function risks after severe pneumonia in AIDS patients
This study looks at why some people with AIDS who recover from severe pneumonia later have trouble breathing. Researchers want to find risk factors so they can help prevent lung damage.
Guangzhou, GuangdongAges 18–65 - NCT06137378RecruitingPhase 2
Pembrolizumab for advanced throat cancer to avoid laryngectomy
This trial tests whether a drug called pembrolizumab (Keytruda) can help people with advanced throat cancer avoid removal of the voice box. You may be eligible if you have a specific type of larynx or hypopharynx cancer that hasn't been treated with radiation or immunotherapy before.
Mannheim, Baden-WürtembergAges 18–70 - NCT06141070RecruitingPhase 3
Adding high-dose radiation to standard treatment for advanced lung cancer
This trial tests whether adding a high, focused dose of radiation to the usual first treatment (chemo and/or immunotherapy) can help people with non-small cell lung cancer that has spread to a limited number of spots (up to 5). The goal is to see if this approach improves how well the treatment works.
GothenburgAges 18 years+ - NCT06141226RecruitingPhase 2
New drug combo for immunotherapy-resistant lung cancer
This trial tests a combination of an immunotherapy drug (TQB2450), a targeted therapy (anlotinib), and chemotherapy for people with advanced non-small cell lung cancer whose cancer stopped responding to prior immunotherapy. It aims to find a new option when the first treatment didn't work anymore.
Huizhou, GuangdongAges 18–75 - NCT06142253Recruiting
Water exercise for long COVID brain fog
This study tests whether water-based exercise (like swimming or water aerobics) helps veterans recover from long COVID, especially brain fog and memory problems. If you're a veteran with ongoing thinking issues after COVID-19, this may help you improve your symptoms over 8 months.
Palo Alto, CaliforniaAges 18–89 - NCT06143969Recruiting
Ultrasound-guided clot-dissolving treatment for intermediate-high risk pulmonary embolism
This trial tests a treatment that uses ultrasound to guide a thin tube (catheter) to deliver clot-busting medicine directly into the blood clot in your lung. It may be an option for people whose clot is serious but not yet causing shock, and who have symptoms that started within the last two weeks.
Milan, ItaliaAges 18 years+ - NCT06144476Recruiting
Lung inflammation study in healthy and diseased lungs
This study compares the lungs of people with airway disease to healthy volunteers to understand inflammation and lung function. You may be eligible if you have airway disease or are a healthy adult.
London, LondonAges 18 years+ - NCT06144996Recruiting
Canadian bronchiectasis and NTM patient registry study
This study will build a Canadian registry for people with bronchiectasis (not from cystic fibrosis) and NTM infections. The goal is to track health outcomes over time to improve care.
Calgary, AlbertaAges 18–120 - NCT06145828Recruiting
Testing a blood filter for severe pneumonia or sepsis in AIDS patients
This study tests a technique that filters harmful substances from the blood of people with AIDS who have severe pneumonia or septic shock. The goal is to see if this filter helps them recover better.
Guangzhou, GuangdongAges 18–65 - NCT06145841Recruiting
Gene test to guide infection treatment in AIDS
This study is for people with HIV/AIDS who develop severe pneumonia or septic shock. It uses a special genetic test (metagenomic next-generation sequencing) to find the exact germ causing the infection so doctors can choose the right antibiotic.
Guangzhou, GuangdongAges 18–65 - NCT06147414Recruiting
Blood test for genetic disorders in pregnancy
This study tests a safer blood test to check for certain genetic disorders during pregnancy, instead of an invasive procedure like amniocentesis. It's for pregnant women who are at risk of passing on a known genetic condition.
ParisAges 18 years+ - NCT06147570RecruitingPhase 2
Study of HS-10365 for RET fusion-positive lung cancer
This trial tests an experimental drug called HS-10365 for people with advanced or metastatic non-small cell lung cancer that has a specific genetic change called a RET fusion. The drug aims to block the growth of cancer cells with this mutation.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06148324Recruiting
Wellness program for traumatic brain injury recovery
This study tests a wellness program for people who had a moderate or severe traumatic brain injury (TBI) at least a year ago. The program is done online, so you can join from home, and it aims to help you with your recovery and well-being.
New York, New YorkAges 18–70 - NCT06148467Recruiting
Understanding breathing patterns and adjusting ventilator support
This study looks at a specific breathing pattern called reverse triggering in people with ARDS (a serious lung condition) who are on a ventilator. The goal is to see how adjusting the ventilator settings affects this pattern and improves breathing coordination.
GuadalajaraAges 18–90 - NCT06150352Recruiting
Sleep apnea and memory in older adults with mild concerns
This trial looks at how sleep apnea affects memory and brain health in people who have mild memory problems or are worried about their memory. You will have a sleep study and brain scans to see if treating sleep apnea could help protect your thinking skills.
Hong KongAges 50–80 - NCT06151405Recruiting
Diet study for adults with asthma
This study tests whether a specially designed diet plan can help adults whose asthma is not well controlled. You will use a smartphone app to track your food and symptoms, and the study will provide dietary guidance.
Baton Rouge, LouisianaAges 18–65 - NCT06152107Recruiting
BTVA Treatment for Severe Emphysema Study
This study tests a new bronchoscopic treatment called BTVA for people with severe emphysema. It uses heat to shrink damaged parts of the lung to improve breathing.
Zhengzhou, HenanAges 18 years+ - NCT06152744Recruiting
Testing ECMO lung function at high altitude
This study looks at how well the ECMO machine works in high-altitude areas. It tests the oxygen exchange in the machine to help improve care for patients at high elevations.
Beijing, Beijing MunicipalityAges 18–70 - NCT06153173RecruitingPhase 2
Mirdametinib for histiocytic disorders
This trial tests a drug called mirdametinib for people with histiocytic disorders, which are rare diseases where certain immune cells grow out of control. It may help shrink tumors and improve symptoms when other treatments haven't worked.
Cincinnati, OhioAges 2 years+ - NCT06156176Recruiting
Exercise for COVID-19 fatigue: a feasibility study
This study tests whether a personalized exercise program can help reduce fatigue after a COVID-19 infection. You'll work with a coach over video calls to see if gentle activity can improve your energy levels.
London, OntarioAges 18 years+ - NCT06159699Recruiting
Online survey about health
This trial is a simple online survey. You will answer a questionnaire from your own device, helping researchers learn more about health.
TomskAges 18 years+ - NCT06159660Recruiting
Lung Imaging to Reduce Radiation Side Effects
This trial tests a new way to plan radiation therapy for lung cancer by using a special imaging technique (functional lung imaging) to see which parts of your lungs work best. The goal is to reduce damage to healthy lung tissue while still targeting the cancer.
St Leonards, New South WalesAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,637 recruiting pulmonology studies from the U.S. registry right now, out of 10,624 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.