Pulmonology
Lungs & breathing clinical trials
Asthma, COPD, and other conditions that affect the lungs and breathing. We’re tracking 6,352 recruiting studies in this area right now.
By phase
- Not applicable4,048
- Phase 2834
- Phase 1460
- Phase 3421
- Phase 1/Phase 2312
- Phase 4213
- Phase 2/Phase 364
Top conditions
- Lung Cancer416
- Asthma194
- Non-Small Cell Lung Cancer182
- Non Small Cell Lung Cancer178
- Non-small Cell Lung Cancer157
- Obstructive Sleep Apnea142
- COPD134
- Breast Cancer111
- Pulmonary Hypertension105
- Colorectal Cancer89
- COVID-1988
- NSCLC87
- Chronic Obstructive Pulmonary Disease84
- Chronic Obstructive Pulmonary Disease (COPD)78
- Cystic Fibrosis77
- Interstitial Lung Disease75
- Ovarian Cancer71
- Pneumonia68
Leading sponsors
- Assistance Publique - Hôpitaux de Paris73
- AstraZeneca65
- Mayo Clinic52
- M.D. Anderson Cancer Center45
- National Cancer Institute (NCI)42
- VA Office of Research and Development40
- Shanghai Chest Hospital35
- Memorial Sloan Kettering Cancer Center33
- University Health Network, Toronto33
- GlaxoSmithKline30
Where studies are running
- California385
- Alabama175
- Arizona154
- Florida121
- Massachusetts118
- Maryland115
- New York111
- Texas87
- Pennsylvania82
- Illinois73
Recruiting studies6,352 total
- NCT07075926Recruiting
Heart ultrasound to predict breathing tube removal success in ICU
This study uses a heart ultrasound to see if it can help doctors predict when patients in the ICU are ready to have their breathing tube removed. It may help avoid failed extubations and reduce complications.
Istanbul, IstanbulAges 18 years+ - NCT07082179RecruitingPhase 2
Immunotherapy plus chemotherapy for stage III lung cancer
This trial tests combining immunotherapy with chemotherapy for people with stage III non-small cell lung cancer that cannot be removed by surgery. It aims to see if this combination can shrink the tumor and improve outcomes.
NanjingAges 18–75 - NCT07077174Recruiting
Permissive lung-protective ventilation for critically ill patients on a breathing machine
This trial tests whether a more lenient approach to lung-protective ventilation can improve outcomes for patients who need a breathing machine (ventilator) in the intensive care unit. It aims to find a balance that is safer for the lungs while still being effective.
AlmeloAges 18 years+ - NCT07082608Recruiting
Weight loss procedure plus lifestyle changes for sleep apnea
This study tests whether a stomach procedure called endoscopic sleeve gastroplasty (ESG) plus lifestyle changes helps people with sleep apnea lose more weight and improve their breathing compared to lifestyle changes alone. If you have moderate to severe sleep apnea and have struggled to lose weight, this may be an option.
Hyderabad, TelanganaAges 18 years+ - NCT07084610RecruitingPhase 2
Metabolic markers predict response to immunotherapy before lung cancer surgery
This trial tests whether certain markers in your blood or tissue can predict how well immunotherapy works before surgery for early-stage lung cancer. It aims to find out who benefits most from this treatment.
Ribeirão Preto, São PauloAges 18 years+ - NCT07077213Recruiting
PET scan test for TB-related lung scarring
This study uses a special PET scan (called FAPI-74) to see if it can detect fibrosis (scarring) in the lungs of people with active TB. It looks at the scan both at the start of treatment and after 6 months of therapy to understand how the lungs heal.
Cincinnati, OhioAges 18 years+ - NCT07077486RecruitingPhase 4
Testing telitacicept vs cyclophosphamide for lupus lung disease
This trial tests if a new drug called telitacicept works better than a standard lupus medicine (cyclophosphamide) to improve lupus-related lung scarring (interstitial lung disease). It might be an option if your breathing tests are still good enough.
Wuhan, HubeiAges 18–80 - NCT07076836Recruiting
Electroacupuncture for lung cancer patients on immunotherapy
This study tests whether adding electroacupuncture at a specific point on the leg (called Zusanli) can help people with lung cancer who are getting chemotherapy and immunotherapy before surgery. It might reduce side effects and improve response to treatment.
Chengdu, SichuanAges 18–80 - NCT07079592Recruiting
Detecting pulmonary hypertension with AI and EKGs
This trial uses an artificial intelligence program to analyze a standard EKG to see if it can detect pulmonary hypertension (high blood pressure in the lungs). It might help find the condition earlier and without invasive tests.
TaipeiAges 50–85 - NCT07076667Recruiting
Relaxation and Tai Chi for COPD
This study compares two relaxing exercises—Benson's relaxation technique and Tai Chi—to see if they help people with moderate to severe COPD feel better and breathe easier.
Chak Four Hundred Fifty-four, Punjab ProvinceAges 40–50 - NCT07085611Recruiting
Studying vaccine and antibody protection in adults
This trial checks how well antibodies from COVID-19 or monkeypox vaccines or treatments work in adults. It helps researchers understand your protection level.
OrléansAges 18 years+ - NCT07076862RecruitingEarly Phase 1
PET scan study for long COVID symptoms
This study uses a special PET scan to look at inflammation in the body of people with long COVID (symptoms lasting 3+ months after infection). The goal is to understand why symptoms persist and find better ways to help.
Sacramento, CaliforniaAges 18 years+ - NCT07079553Recruiting
Diaphragm stimulation with breathing exercises for COPD
This study tests whether a gentle electrical stimulation on your diaphragm (the muscle that helps you breathe) combined with deep breathing exercises can improve your breathing and quality of life. It is for people with mild to moderate COPD who do not smoke and have a chronic cough with mucus.
Lahore, Punjab ProvinceAges 40–60 - NCT07079150Recruiting
Long-term pegylated interferon study for HBV families with poor outcomes
This study looks at how well pegylated interferon alpha-2b works over the long term for people with chronic hepatitis B who come from families where the virus has caused serious liver problems like cirrhosis or liver cancer. The goal is to see if this treatment can help prevent these bad outcomes in family members.
Xi'an, ShaanxiAges 18–70 - NCT07083557Recruiting
Validation study for lab tests on hormones and metabolism
This study checks if lab tests used for hormone, heart, metabolism, and muscle disorders are accurate and reliable. You might be eligible if you are an adult with a body mass index between 16 and 60.
Columbia, MissouriAges 18–100 - NCT07085182RecruitingPhase 2
Tislelizumab plus radiation for advanced lung cancer
This trial tests combining the immunotherapy drug tislelizumab with radiation therapy for people with advanced non-squamous non-small cell lung cancer that hasn't been treated before. It aims to see if this combination helps control the cancer better than standard treatments.
Zibo, ShandongAges 18–75 - NCT07083973Recruiting
Monitoring lung function with 3D imaging in ARDS
This study is testing a new way to monitor lung function using a 3D electrical imaging device (EIT) while patients with ARDS lie on their stomach to improve breathing. The goal is to see if this imaging helps doctors better understand how the lungs are working.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06051513Recruiting
Testing colistimethate for CRE infection in hospitalized patients
This trial tests a medicine called colistimethate sodium for people in the hospital with a serious infection (pneumonia or bloodstream infection) caused by a resistant bacteria called CRE. The goal is to see if this antibiotic can effectively treat the infection.
Hefei, AnhuiAges 18–85 - NCT06358222Recruiting
Lung cancer trial testing blood test and PET scan for spread
This trial studies if a blood test that looks for tumor DNA combined with a PET-CT scan can better predict if lung cancer has spread to lymph nodes. It may help guide treatment decisions for people with non-small cell lung cancer that hasn't been treated yet.
ShanghaiAges 18–75 - NCT06659042RecruitingPhase 2
Tislelizumab before and after surgery for KRAS-mutated lung cancer
This trial tests whether adding the immunotherapy drug tislelizumab before and after surgery can help people with a specific type of lung cancer (non-squamous NSCLC with a KRAS mutation) that is stage 2 or 3. It aims to improve treatment outcomes by targeting the cancer early.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT06897501Recruiting
Comparing breathing tubes for voice box protection during esophagectomy
This trial compares two types of breathing tubes used during robot-assisted esophageal cancer surgery. One tube blocks one lung (double-lumen tube) and the other tube uses a smaller blocker (bronchial blocker); researchers want to see which causes fewer voice box nerve injuries after surgery.
SeoulAges 19 years+ - NCT03033251Recruiting
Compare high-flow oxygen to noninvasive ventilation for COPD flare-ups
This study compares two breathing support options for people hospitalized with a COPD flare-up and high carbon dioxide levels in the blood. It aims to see which option works better and is safer for breathing and recovery.
Toronto, OntarioAges 40 years+ - NCT04460859Recruiting
Testing an electrical monitor in moderately severe lung failure
This trial tests a bedside breathing and lung-monitoring method that uses small electrodes on the chest. It is meant for people with moderate to severe ARDS (a serious lung inflammation problem) who are on a breathing machine, to help guide care.
São PauloAges 18 years+ - NCT05011877Recruiting
Study for sleep testing after sudden breathing trouble
This trial studies people who unexpectedly end up in the hospital or emergency room because of a sudden worsening in breathing that leads to too much carbon dioxide. It may help doctors understand whether sleep-related breathing issues contribute and how to better prevent repeat episodes.
Toronto, OntarioAges 18 years+
Common questions
- How many lungs & breathing clinical trials are recruiting?
- Clin2 is tracking 6,352 recruiting pulmonology studies from the U.S. registry right now, out of 10,005 we cover in this area in total.
- What does “Lungs & breathing” cover here?
- Asthma, COPD, and other conditions that affect the lungs and breathing. We group each study into lungs & breathing based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a lungs & breathing trial near me?
- Use the search to filter lungs & breathing studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.