Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 1,962 recruiting studies in this area right now.
By phase
- Not applicable1,544
- Phase 2144
- Phase 384
- Phase 182
- Phase 460
- Phase 1/Phase 235
- Phase 2/Phase 313
Top conditions
- Periodontitis103
- Nasopharyngeal Carcinoma74
- Periodontal Diseases50
- Dental Caries46
- Head and Neck Cancer35
- Gingivitis34
- Oral Cancer32
- Periodontal Disease29
- Dental Implant28
- Gingival Recession25
- Alveolar Bone Loss24
- Nasopharyngeal Carcinoma (NPC)24
- Sjogren's Syndrome24
- Tooth Loss24
- Temporomandibular Disorders (TMD)22
- Oropharynx Cancer21
- Peri-Implantitis21
- Temporomandibular Joint Disorders20
Leading sponsors
- Cairo University77
- Sun Yat-sen University50
- Mansoura University25
- Ain Shams University24
- Postgraduate Institute of Dental Sciences Rohtak24
- Tanta University24
- Al-Azhar University23
- Universidad Complutense de Madrid16
- University of Baghdad16
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California44
- Texas26
- Maryland21
- Massachusetts21
- Florida20
- New York19
- Pennsylvania19
- Ohio18
- Alabama17
- Michigan15
Recruiting studies1,962 total
- NCT07463859Recruiting
Treating gum disease and bad breath in diabetes patients
This trial tests whether combining standard gum treatment with a light-activated therapy can reduce bad breath in people with type 2 diabetes and advanced gum disease.
Bauru, São PauloAges 18–70 - NCT07471555Enrolling by invitation
Vascular access and intraosseous study for nursing students
This trial tests a teaching method for inserting a special needle into bone (intraosseous access) and regular IV lines. It is only for 4th year nursing students.
Valencia, ValenciaAges 18 years+ - NCT07465952Recruiting
Do price cuts help people get preventive dental care?
This trial tests whether offering different price discounts on dental check-ups encourages people who haven't been to the dentist recently to schedule a preventive visit. You may be eligible if you have a medical appointment soon and have not seen a dentist in the last 6 months.
SantiagoAges 18–70 - NCT04544969Recruiting
Testing blood markers to guide chemo for metastatic nasopharyngeal cancer
This study looks at special blood markers (CTCs) to see how sensitive your cancer is to chemotherapy and to better predict how well treatment may work. If you have metastatic nasopharyngeal cancer and can’t have local treatment, this may help match you to more effective chemo plans.
Guangzhou, GuangdongAges 18–70 - NCT07459049RecruitingPhase 4
Ibuprofen for gum inflammation after deep cleaning
This trial tests whether ibuprofen can help calm gum inflammation after a deep cleaning for periodontitis. It is for adults with moderate-to-severe gum disease who are otherwise healthy.
BaghdadAges 18 years+ - NCT07455656Recruiting
Vitamin D3 or gum massage for faster canine movement with braces
This study tests whether applying vitamin D3 or a special gum massage (corticision) next to the teeth can help move your eye teeth (canines) faster after your upper first premolars are removed for braces. It is for teenagers or young adults who already need that extraction as part of their orthodontic plan.
Cairo, Cairo GovernorateAges 13–20 - NCT07456163Recruiting
How zirconia abutments affect gum and bone around dental implants
This study compares how well the gum and bone around dental implants heal when using zirconia (a white ceramic) versus standard metal abutments. It aims to see if zirconia leads to healthier tissues around single-tooth replacements.
Piracicaba, São PauloAges 18–70 - NCT07457749RecruitingEarly Phase 1
Comparing two tooth-colored fillings for back teeth cavities
This study tests a new self-hardening filling material against a light-activated bioactive filling for cavities between back teeth. The goal is to see which material works better and lasts longer.
Cairo, El Sherouk CityAges 18–47 - NCT07459075RecruitingPhase 4
Bone graft with hormone for sinus lift before dental implants
This trial tests if adding parathyroid hormone to a bone graft improves bone growth in the upper jaw before placing dental implants. It may help people who have lost teeth and have very little bone in the sinus area.
BaghdadAges 18 years+ - NCT07462156Recruiting
AI Tool for Dental Students to Self-Assess Tooth Preparations
This trial tests a new AI-powered digital tool that helps dental students self-check their tooth preparations. If you are a third-year preclinical dental student who has completed the basic course but hasn't used digital assessment tools before, you may be able to join this study to see if the AI tool improves your skills.
El AlameinAges 18–20 - NCT07459296RecruitingPhase 3
Becotatug vedotin plus sintilimab for advanced nasopharyngeal cancer
This trial tests a combination of two drugs, becotatug vedotin and sintilimab, for patients with a type of nasopharyngeal cancer that has spread to nearby lymph nodes but not to distant organs. It aims to see if this treatment can help control the disease.
Nanning, GuangxiAges 18–70 - NCT07460076Recruiting
Immediate tooth implant with bone graft from the upper jaw
This trial tests placing a dental implant right after removing a tooth, using a small piece of bone from the back of your upper jaw to rebuild the gum area. It may help people who need a front tooth replaced and have a bone defect that requires this type of graft.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT06442787Recruiting
New 3D Planning for Jaw Surgery
This study tests a new way to plan jaw surgery using 3D computer models, custom guides, and plates. It may help people with a certain type of jaw misalignment get more precise results from their surgery.
Istanbul, FatihAges 18–55 - NCT06796270Recruiting
Short-course radiation for nasopharyngeal cancer
This trial tests a shorter course of radiation therapy for people with nasopharyngeal cancer, a type of head and neck cancer. The goal is to see if a hypofractionated (fewer, larger doses) approach is safe and effective.
Haikou, HainanAges 18–75 - NCT05451303Recruiting
Testing for oral and throat cancer risk with a mouth test
This trial studies how well an at-home or clinic mouth test (OralViome Cancer Testing System) can detect signs of risk for oral or throat cancer. You may benefit by getting cancer-risk testing if you are considered high risk, though results will guide whether further evaluation is needed.
New York, New YorkAges 18 years+ - NCT06148818Recruiting
Neck exercises for jaw pain relief
This study tests whether special neck exercises can help reduce jaw pain in people who have both jaw (TMJ) problems and neck pain. If you have had jaw pain for at least 3 months and also have achy neck pain, you may be able to join.
TrabzonAges 18–55 - NCT06174428Recruiting
Study of a new oral and throat cancer test
This study is testing a new, simple test that looks for signs of oral or throat cancer. If you have a suspicious spot or symptom, this test might help find out if it's cancer.
St Louis, MissouriAges 18 years+ - NCT06646432Recruiting
Gum Recession Treatment: Tissue Graft vs. Blood Concentrate
This trial is testing two methods for fixing receding gums: using a small piece of tissue from the roof of your mouth (connective tissue graft) versus using a special concentrate of your own blood (injectable platelet-rich fibrin). Both are done through a tiny tunnel under the gum, and the goal is to cover the exposed root and make your gums look and feel healthier.
IsmailiaAges 21 years+ - NCT06798090Recruiting
Comparing 3D-printed vs. traditional dental space maintainers
This trial tests two ways of making a small dental device that holds space for adult teeth when baby molars are lost early. It compares a 3D-printed version with a conventionally made one, to see which works better and is more comfortable.
Aydin, AydınAges 5–8 - NCT05358262RecruitingPhase 2
Heated, humid air during stem cell transplant to reduce mouth injury
This Phase 2 study tests whether breathing in warm, very humid air through your nose during stem cell transplant (with high-dose melphalan) can reduce painful mouth or throat injury. It may help your comfort and recovery during and after treatment.
Edmonton, AlbertaAges 18 years+ - NCT07453147Recruiting
Gum graft surgery for multiple teeth with recession
This study compares two ways of doing a gum graft surgery to cover exposed tooth roots. It may help patients who have gum recession on multiple teeth and want a less invasive treatment.
Liège, LiègeAges 18 years+ - NCT07445516Recruiting
Bite adjustment for TMD: long-term follow-up
This trial follows up with people who previously had a dental bite adjustment (occlusal equilibration) for TMD (jaw or face muscle/joint pain). It compares their long-term results with a group that received a 'sham' (fake) procedure.
Santiago de Compostela, A CoruñaAges 18–85 - NCT07446790Recruiting
Comparing two digital methods for full-arch implant bridges
This trial tests a faster digital scanning method using a special camera (photogrammetry) versus a standard intraoral scanner for making a full set of implant-supported teeth. It aims to see which method leads to fewer problems with the final restoration.
CairoAges Any age - NCT07448571Recruiting
Testing i-PRF for better root canal retreatment healing
This study tests whether using a special platelet-rich concentrate (i-PRF) during a root canal retreatment can help heal infection at the tip of the root better than standard retreatment alone. It is for adults with a previously treated upper front tooth that now shows signs of infection on X-ray.
IstanbulAges 18–50
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 1,962 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,741 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
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- Genetic & congenital
- Bones, joints & muscles
- Pain
- Injuries & trauma
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.