Dentistry & oral health
Mouth & dental clinical trials
Conditions of the teeth, gums, mouth, and jaw. We’re tracking 2,053 recruiting studies in this area right now.
By phase
- Not applicable1,631
- Phase 2148
- Phase 183
- Phase 381
- Phase 458
- Phase 1/Phase 236
- Phase 2/Phase 316
Top conditions
- Periodontitis108
- Nasopharyngeal Carcinoma79
- Periodontal Diseases57
- Dental Caries49
- Gingivitis35
- Head and Neck Cancer35
- Oral Cancer35
- Dental Implant30
- Sjogren's Syndrome29
- Gingival Recession27
- Periodontal Disease27
- Alveolar Bone Loss23
- Nasopharyngeal Carcinoma (NPC)23
- Peri-Implantitis23
- Tooth Loss22
- Oropharynx Cancer21
- Temporomandibular Disorders (TMD)21
- Trigeminal Neuralgia21
Leading sponsors
- Cairo University91
- Sun Yat-sen University53
- Ain Shams University30
- Mansoura University30
- Postgraduate Institute of Dental Sciences Rohtak24
- Al-Azhar University23
- Tanta University23
- University of Baghdad19
- Universidad Complutense de Madrid18
- Assistance Publique - Hôpitaux de Paris14
Where studies are running
- California40
- Texas27
- Massachusetts22
- Ohio22
- Pennsylvania22
- New York20
- Maryland19
- Florida18
- Alabama16
- Michigan15
Recruiting studies2,053 total
- NCT07147764Recruiting
Pain education plus physiotherapy for jaw pain
This trial compares two treatments for long-lasting jaw or face pain: physiotherapy alone versus physiotherapy combined with education about how pain works. It aims to find which approach helps more.
Istanbul, KavacikAges 18–65 - NCT07153276RecruitingPhase 4
Laser vs estrogen cream for vaginal dryness in Sjögren's
This trial compares two treatments for vaginal dryness in women with Sjögren's disease: a CO2 laser procedure versus a topical estrogen cream called promestriene. The goal is to see which option works better to relieve dryness and discomfort.
São Paulo, São PauloAges 30–65 - NCT07158528Recruiting
Gum grafting study for multiple receding gums in upper jaw
This study compares two gum grafting techniques (CAF and TCAF) to see which one works better for treating multiple receding gums in the upper jaw. It may help if you have gum recession and want a treatment to cover the exposed roots.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07158541Recruiting
Comparing Two Gum Treatments for Lower Front Recession
This study compares two techniques (TCAF and MTUN) for treating a single gum recession in the lower front part of the mouth. It will help determine which method works best for healing and appearance.
Ghent, Oost-VlaanderenAges 18 years+ - NCT07162077Recruiting
A new treatment for white spots on front teeth
This trial tests a special technique (etch-bleach-seal) using Icon® to treat white or cloudy spots on permanent front teeth caused by a condition called Molar Incisor Hypomineralization (MIH). This approach may improve the appearance of these spots without drilling or filling.
LatakiaAges Any age - NCT07170358Recruiting
Biomarker screening for head and neck cancer radiation therapy
This trial is looking for people with head and neck cancer who are about to start radiation therapy (possibly combined with other treatments). The goal is to find biomarkers that may help predict how well the treatment works or what side effects might occur.
Nanjing, JiangsuAges 18–75 - NCT07171151Recruiting
Cyst fluid study for disease markers
This trial looks at fluid from cysts to find markers that might show disease. If you have a cyst and are not pregnant or breastfeeding, you may be able to join.
SanliurfaAges 12–80 - NCT07173296Recruiting
Bleaching gel application and tooth sensitivity
This study tests two different ways of applying a gentle bleaching gel to see if one causes less tooth sensitivity. It's for people who want to whiten their front teeth and have no history of sensitivity or prior whitening.
IrbidAges 18–35 - NCT07177521Recruiting
Short dental implants after tooth extraction
This study tests whether short implants placed right after a tooth is pulled are stable and work well. It may be a good option if you need a single back tooth replaced and are generally healthy.
BariAges 18–75 - NCT07180901Recruiting
Optimizing care for head and neck cancer surgery patients
This trial uses a computer system to send reminders and tracking alerts to doctors and patients, aiming to improve care and outcomes after surgery for head and neck cancer. It may help you stay on track with your treatment plan.
Montreal, QuebecAges 18 years+ - NCT07181967Recruiting
SDF vs fluoride varnish for cavity bacteria in kids
This study compares a silver-containing liquid (SDF) to a fluoride varnish to see which works better at reducing cavity-causing bacteria in children's mouths. It may help your child if they have cavities in their baby teeth.
Asyut, Asyut GovernorateAges 3–8 - NCT07188584RecruitingPhase 3
Smaller radiation vs. standard after chemo-immunotherapy for advanced nasopharyngeal cancer
This trial tests whether a smaller radiation treatment area is as effective as the usual larger one for people whose metastatic nasopharyngeal cancer has responded well to first-line chemotherapy plus immunotherapy. It aims to reduce side effects while keeping the cancer under control.
ZhuhaiAges 18–70 - NCT07191522Recruiting
Light therapy for gum disease around dental implants
This trial tests if a special light treatment (photodynamic therapy) can help treat infection and inflammation around dental implants without surgery. It may be an option for people with mild to moderate peri-implantitis who don't smoke and have healthy gums otherwise.
Almada, Monte Da CaparicaAges 18 years+ - NCT07195032RecruitingPhase 4
MMR vaccine safety in kids after heart transplant
This trial tests whether the MMR (measles, mumps, rubella) vaccine is safe and works well for children who have had a heart transplant. It may help protect you from these diseases if you haven't had the vaccine or no longer have immunity.
Kansas City, MissouriAges 1–17 - NCT07195357Recruiting
Dental wear and sensitivity study for adults
This study looks at why some people have more tooth wear and sensitivity. If you are a dental clinic patient with at least 10 natural teeth, you may help researchers understand what causes these problems.
Indianapolis, IndianaAges 18 years+ - NCT07200258Recruiting
Comparing Two Ways to Treat Gum Recession
This trial compares two surgical techniques (MCAT and VISTA) to fix receding gums on multiple teeth. It tests which method better restores gum thickness and reduces tooth sensitivity or cosmetic concerns.
MadridAges 18 years+ - NCT07203911Recruiting
Ultrasound guidance for oral cancer surgery
This trial tests whether surgeons can use ultrasound during surgery to better guide the removal of oral cancer. It may help ensure all cancer is removed while sparing healthy tissue.
Stanford, CaliforniaAges 18 years+ - NCT07205172Recruiting
Gum looks and teeth crowding in children
This study looks at how the appearance of the gums relates to crowding of teeth in children. It will examine kids in different stages of tooth development to see if there is a link.
RomaAges 5–16 - NCT07205588Recruiting
Dental health check using digital tools
This study uses digital tools to assess dental problems in adults who are new to a dental practice or haven't visited in the last six months. It aims to understand how well these tools work for finding dental issues.
ChâtillonAges 18 years+ - NCT07208643Recruiting
Long-term stability of dental implant infection treatments
This study checks if previous treatments for peri-implantitis (infection around dental implants) stay effective after 3 years. It follows patients who already finished a prior clinical trial comparing surgical and non-surgical treatments.
Sant Cugat del Vallès, BacelonaAges Any age - NCT07209189RecruitingPhase 2
Chemo and immunotherapy before surgery for head and neck cancer
This trial tests a combination of chemotherapy and an immunotherapy drug called Toripalimab before surgery for certain head and neck cancers. The goal is to see if this approach can reduce the extent of treatment needed while still being effective.
Baltimore, MarylandAges 18 years+ - NCT07210359Recruiting
New treatment for immature teeth
This trial tests a regenerative treatment for immature permanent teeth (front teeth with developing roots) in children and teens. The goal is to help the tooth's pulp heal and allow the root to continue growing naturally.
Kafr ash Shaykh, Kafr ElsheikhAges 9–15 - NCT07210762Recruiting
Gum cleft during canine tooth movement
This study looks at whether a small gum opening (gingival cleft) forms when a canine tooth is pulled back after premolar removal. It may help understand how gums heal during orthodontic treatment.
Karachi, SindhAges Any age - NCT07211711Recruiting
Splint therapy for tinnitus linked to jaw joint issues
This trial tests if a custom mouthpiece (occlusal splint) can relieve ringing in the ears (tinnitus) that started along with jaw or face pain (TMD). It aims to see if stabilizing the jaw helps reduce both the noise in your ears and the discomfort.
São Paulo, São PauloAges 18 years+
Common questions
- How many mouth & dental clinical trials are recruiting?
- Clin2 is tracking 2,053 recruiting dentistry & oral health studies from the U.S. registry right now, out of 3,969 we cover in this area in total.
- What does “Mouth & dental” cover here?
- Conditions of the teeth, gums, mouth, and jaw. We group each study into mouth & dental based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a mouth & dental trial near me?
- Use the search to filter mouth & dental studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
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- Pain
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Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.