Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,575 recruiting studies in this area right now.
By phase
- Not applicable2,950
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University20
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas51
- Illinois40
- North Carolina40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,575 total
- NCT07787221Recruiting
Pain relief blocks after kidney removal surgery
This study compares two types of nerve blocks to see which one provides better pain relief after surgery to remove a kidney. If you are having this surgery, the results may help your doctors choose the best way to manage your pain.
CairoAges 18–65 - NCT07784504Recruiting
Physical therapy for chronic neck pain
This study tests different physical therapy approaches to improve pain and quality of life in people with long-lasting neck pain that hasn't fully improved with prior therapy. Participants must be 18-65, have had neck pain for over 3 months, and still have at least moderate pain and disability.
Istanbul, BeykozAges 18–65 - NCT07787871Recruiting
Acupressure for pain after laparoscopic hernia repair
This study tests whether acupressure can reduce pain after laparoscopic hernia repair surgery. If you are having this type of surgery, acupressure might help you manage pain without extra medication.
Istanbul, IstanbulAges 18–75 - NCT07790874Recruiting
Eye exercises for neck-related dizziness
This trial tests whether eye exercises can help reduce dizziness and neck pain in people with chronic neck-related dizziness that started without an injury. It may help you if your dizziness has lasted for at least 3 months and is linked to your neck.
Faisalābad, Punjab ProvinceAges 20–40 - NCT07789340Recruiting
Radiofrequency treatment for knee osteoarthritis pain
This study compares two types of radiofrequency treatment to reduce knee pain from osteoarthritis. It may help people whose knee pain has not improved with other treatments like physical therapy or injections.
Tanta, El-GharbiaAges 50 years+ - NCT07791784Recruiting
Pain relief and shoulder exercises for shoulder pain
This study tests a program that combines pain management education with shoulder exercises to help people with long-lasting shoulder pain. The goal is to see if this approach reduces pain and improves daily function.
Ballerup MunicipalityAges 18–65 - NCT07791355Recruiting
Testing pain reprocessing therapy for chronic pain
This study tests a psychological treatment called Pain Reprocessing Therapy (PRT) for people with chronic primary pain like fibromyalgia or back pain. It aims to see if this treatment is feasible and helpful in a specialist pain clinic.
StockholmAges 18 years+ - NCT07785973Recruiting
Comparing two root canal fillings for pain and healing
This study compares two types of root canal filling materials to see which one causes less pain after the procedure and helps the infection at the tooth root heal better. It focuses on upper front teeth with an active infection.
MinyaAges 20–40 - NCT07788027Recruiting
Comparing two root canal cleaning methods for reducing post-procedure discomfort
This study compares two different methods of delivering a cleaning solution during root canal treatment to see which one causes less pain and discomfort after the procedure. Participants will be randomly assigned to one of the two methods.
MinyaAges 18–45 - NCT07776600Recruiting
Pain coaching by text or phone for veterans
This study tests a text or phone chatbot that offers pain coaching to veterans with chronic pain. It may help you manage your pain and avoid extra clinic visits.
Augusta, GeorgiaAges 18 years+ - NCT07776379Recruiting
Predicting recovery with BDNF blood levels in chronic low back pain
This study looks at whether a protein in your blood, called BDNF, can help predict how well you might do with chronic low back pain. By participating, you may help doctors better understand and treat this condition.
Daegu, DaeguAges 20–80 - NCT07777627Recruiting
Comparing two spinal pain relievers after lumbar spine surgery
This trial compares two different medications (morphine and dexmedetomidine) given through a spinal injection to see which provides better pain relief after lumbar spine surgery. If you qualify, you will receive one of these treatments or a placebo to help manage your pain after the operation.
Tanta, El-GharbiaAges 21–60 - NCT07779486Recruiting
Intravenous magnesium for acute headache pain relief
This study compares two doses of intravenous (IV) magnesium to see which is more effective at relieving acute headache pain in the emergency department. It aims to provide a fast and effective treatment option for migraine, tension-type, or cluster headaches.
MonastirAges 18 years+ - NCT07776366Recruiting
Study of disc protein levels and disc wear
This study looks at a protein called periostin in the discs of the lower back to see if it relates to how worn down the discs are, which might help improve future treatments.
Daegu, DaeguAges 20–80 - NCT07776327Recruiting
Therapy options for neck and shoulder pain
This study compares two treatments—positional release therapy and dry needling—for neck and shoulder pain caused by a tight muscle. It aims to see which one works better.
Karachi, SindhAges 18–40 - NCT07778069Enrolling by invitation
Virtual reality for children having joint steroid injections
This study tests whether using virtual reality (VR) during a steroid joint injection helps children feel less pain and anxiety. If it works, it could make the procedure easier for patients from 5 to 17 years old.
Columbus, OhioAges 5–17 - NCT07780396Recruiting
Posture exercises for forward head posture
This study tests whether posture correction exercises improve the electrical activity of neck and jaw muscles in young adults with forward head posture. Participation may help you improve your posture and prevent future jaw or neck issues.
BeirutAges 18–30 - NCT07780942Recruiting
Testing a smartwatch for detecting heart attacks in people with chest pain
This study is testing how well a smartwatch can detect a specific type of heart attack (STEMI) in people who come to the hospital with chest pain. It aims to see if the smartwatch's ECG feature is accurate compared to standard hospital tests.
Cartagena, MurciaAges 18 years+ - NCT07777081Recruiting
How your brain and body recover after a wrist fracture
This study looks at how your brain and body heal after a wrist fracture. By joining, you'll help doctors understand recovery better, which could improve care for future patients.
Cambridge, CambridgeshireAges 18 years+ - NCT07779551Enrolling by invitation
Pain relief after thyroid surgery: comparing two numbing drugs
This study compares two medications, bupivacaine and ropivacaine, given as a neck block before thyroid surgery to see which provides better pain relief after the operation. It may help reduce post-surgery discomfort.
Sargodha, Punjab ProvinceAges 20–40 - NCT07781930Recruiting
Comparing two pain blocks after kidney laparoscopy
This study compares two types of pain-relieving injections given during kidney surgery to see which one works better. It may help reduce pain after surgery and improve recovery.
CairoAges 18–40 - NCT07783386Recruiting
Comparing nerve block volumes for breast surgery pain
This study compares different volumes of a nerve block (SPSIP) for pain relief after breast surgery. It aims to see if one volume provides better pain control with fewer side effects.
Nilufer, BursaAges 18–75 - NCT04548375Recruiting
Registry study of pain relief from spinal cord stimulation
This is an observational registry that follows people who have a spinal cord stimulation (SCS) implant for approved pain-related conditions. It aims to learn how well SCS works in real-world care, which may help improve treatment and outcomes over time.
Reno, NevadaAges Any age - NCT05752396Recruiting
Study of Pain Patterns Over Time in Kids
This study follows kids who have a specific type of chronic pain (headaches, stomach pain, or muscle/joint pain) to better understand how pain changes over time. It also checks whether certain factors are linked to those pain patterns.
Cincinnati, OhioAges 10–19
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,575 recruiting pain medicine studies from the U.S. registry right now, out of 6,452 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.