Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,749 recruiting studies in this area right now.
By phase
- Not applicable3,095
- Phase 4251
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Mayo Clinic28
- Tanta University28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas51
- Ohio47
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,748 total
- NCT06588777Recruiting
Two Nerve Blocks for Pain After Gallbladder Surgery
This study compares two types of nerve blocks for pain relief after laparoscopic gallbladder surgery. If you take part, you will receive either an ultrasound-guided M-TAPA block or a quadratus lumborum block, and the researchers will measure how well each controls your pain.
CairoAges 21–71 - NCT06620133Recruiting
Pain education and goal setting for chronic low back pain
This trial tests whether learning about pain and setting your own exercise goals helps people with long-term low back pain become more active. You will receive online sessions and support to safely increase your physical activity.
Sydney, New South WalesAges 18 years+ - NCT06636864Enrolling by invitation
Morphine injection for better recovery after colon cancer surgery
This trial tests if giving a single injection of morphine into the spinal fluid can improve how well you feel and recover after laparoscopic surgery for colorectal cancer. The morphine is given through a spinal needle before surgery, and it may help control pain during and after the procedure.
Guangzhou, GuangdongAges 18 years+ - NCT06671860Recruiting
Exercises and hands-on therapy for neck pain
This study tests whether combining eye exercises with hands-on therapy helps people with non-specific neck pain (pain not caused by a known injury or disease). It may help improve how your neck moves and reduce discomfort.
IstanbulAges 18–65 - NCT06619860RecruitingPhase 2
VX-993 for diabetic nerve pain
This trial tests a new medicine called VX-993 for people with diabetes who have had nerve pain in both feet or legs for at least a year. The goal is to see if it reduces pain and is safe.
Cullman, AlabamaAges 18–80 - NCT06679569Recruiting
Deep muscle relaxants for less pain after children's belly-button surgery
This study looks at whether giving a deep muscle relaxant during your child's belly-button surgery can reduce pain after the operation. It may help kids feel better and recover more comfortably.
Seoul, SeoulAges 2 months–7 years - NCT06538792Recruiting
Proprioception and strength after ACL reconstruction
This study looks at how well people regain body awareness, muscle strength, and fear of movement after ACL knee surgery. It may help understand recovery patterns in the first year after surgery.
IstanbulAges 18–35 - NCT06580899Enrolling by invitationPhase 4
Knee pain pump study for single knee replacement surgery
This study tests whether a small pain pump placed in your knee joint during surgery can help control pain after a single knee replacement. It is for people who are having outpatient knee replacement surgery and have not been taking strong pain medicines recently.
Charlotte, North CarolinaAges 18 years+ - NCT06525740RecruitingPhase 4
Comparing two pain medicines for gynecologic cancer surgery
This trial compares two different pain medicines (methadone given by mouth or IV vs. hydromorphone given through a spinal injection) after surgery for gynecologic cancer. It aims to find which option provides better pain relief with fewer side effects.
Rochester, MinnesotaAges Any age - NCT07255248RecruitingPhase 4
Knee fat pad pain study for young female athletes
This study tests a treatment for knee fat pad pain in teenage girls who play organized sports. It aims to see if a specific injection helps after physical therapy hasn't worked.
Norwood, MassachusettsAges 12–18 - NCT06584695Recruiting
Nerve blocks for pain after open kidney surgery
This study compares two types of nerve blocks to see which one provides better pain relief after open kidney cancer surgery. If you qualify, you'll receive one of the two blocks before your surgery to help manage pain afterwards.
CairoAges 18–65 - NCT06573515Recruiting
Comparing two therapies for neck pain in breastfeeding mothers
This study tests if high-tone power therapy or interferential current therapy helps reduce neck pain in new mothers who are exclusively breastfeeding. It aims to find a safe, drug-free option to relieve discomfort.
CairoAges 18–35 - NCT06568289Recruiting
Numbing medicines for pain after childbirth with a cut
This trial tests two numbing medicines (lidocaine and bupivacaine) to see which works better for pain after a cut (episiotomy) during childbirth. If you are having your first baby and deliver vaginally with an episiotomy, you may be able to join and receive a local injection for pain relief.
CairoAges 18–40 - NCT06534203Recruiting
Physical demands on caregivers in long-term care
This study measures the physical tasks and demands faced by full-time caregivers who work with residents in a long-term care facility. The goal is to help improve workplace safety and care quality.
Moncton, New BrunswickAges 19 years+ - NCT06535269Recruiting
Pain after hemorrhoid surgery: standard vs bipolar sealer
This study compares two ways of removing hemorrhoids during surgery: one uses a standard electric tool, the other uses a special device (Caiman®) that seals blood vessels. It aims to see which method causes less pain after the operation.
Sabadell, BarcelonaAges 18–65 - NCT06534125Recruiting
Acupuncture to prevent joint pain from hormone therapy in Black women
This study tests whether acupuncture can prevent joint pain caused by a common hormone therapy pill (aromatase inhibitor) in Black women who have finished treatment for early-stage breast cancer.
Atlanta, GeorgiaAges 18 years+ - NCT06576219Enrolling by invitation
My Life is Music group therapy for teens with persistent pain
This study tests whether a group therapy program called 'My Life is Music' can help teenagers with ongoing pain. It looks at how well the program works and if it's a good fit for teens.
HelsinkiAges 13–17 - NCT06544239Enrolling by invitation
Virtual reality training for basketball players with challenges
This trial tests if virtual reality exercises can help professional basketball players with physical or mental challenges improve their skills. It focuses on people who have uneven strength or movement between sides of the body.
Jinan, ShandongAges 17–29 - NCT06474897Recruiting
Comparing mobilization and ozone therapy for shoulder pain
This study compares two treatments—gentle movement exercises and ozone injections—for shoulder pain. It aims to see which option helps people with shoulder impingement feel better faster.
ElâzığAges 18–65 - NCT06387706Recruiting
Web-based pain program for older adults
This study tests a fun, web-based program (GAP) to help older adults manage chronic pain through light exercise and coping skills. It's designed for Cantonese speakers who can use a smartphone.
Hong KongAges 60 years+ - NCT06413667Recruiting
Chronic whiplash and headache study
This study uses MRI to look at the alignment of the atlas (the top bone in your neck) and nearby tissues in people with chronic whiplash or tension headaches. The results may help researchers better understand these conditions.
AmsterdamAges 18–75 - NCT06421558Recruiting
Electrical stimulation for lower back nerve pain
This study tests whether a mild electrical stimulation applied to the lower back can help relieve pain from a pinched nerve. It involves weekly sessions for 6 weeks.
Escondido, CaliforniaAges 18 years+ - NCT06399185RecruitingPhase 4
Medicines for catheter discomfort after bladder or prostate surgery
This study tests whether two medicines, dexmedetomidine and esketamine, can reduce discomfort from a urinary catheter after bladder or prostate surgery. If you are having this type of surgery and need a catheter, this trial may help find a better way to manage that discomfort.
Beijing, Beijing MunicipalityAges 18 years+ - NCT06456099Recruiting
Home exercises with a steroid shot for hip pain
This trial tests whether adding a steroid injection to a home exercise program helps people with long-term pain on the outside of the hip. It aims to find a better way to manage your pain and improve daily function.
GistrupAges 35 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,749 recruiting pain medicine studies from the U.S. registry right now, out of 6,757 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.