Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,751 recruiting studies in this area right now.
By phase
- Not applicable3,098
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio47
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,750 total
- NCT07122843Recruiting
VR and AI meditation for hospital pain relief
This study tests if a virtual reality (VR) meditation program can help reduce pain in hospitalized patients. If you have at least moderate pain (4 out of 10 or higher) and can speak English or Spanish, you may be able to join.
Los Angeles, CaliforniaAges 18 years+ - NCT07122973Recruiting
Mapping itch and pain receptors on the skin
This study looks at how the skin senses itch and pain by applying a small amount of chili cream (capsaicin) to different spots. It may help doctors better understand pain and itch conditions in the future.
Gistrup, AalborgAges 18–60 - NCT07123181Recruiting
Oregano and basil for unstable angina
This trial tests if eating oregano and basil leaves can help people with unstable angina, a type of chest pain from heart disease. It looks for improvements in heart health without using strong medications.
Tehran, Tehran ProvinceAges 30–75 - NCT07123233Recruiting
Cognitive behavioral treatment for chronic face and mouth pain
This trial tests a new cognitive-behavioral therapy (a type of talk therapy) for people with chronic orofacial pain – pain in the face, mouth, or jaw that has lasted for months. The goal is to learn skills to help manage pain and improve quality of life.
MilanAges 18–70 - NCT07123532Recruiting
Shoulder blade movement study in physical therapists
This trial looks at how common a certain shoulder blade movement problem (scapular dyskinesis) is among physical therapists. It will help researchers understand why some therapists might have shoulder issues and how to prevent them.
CairoAges 27–40 - NCT07123805Recruiting
Acupuncture for knee replacement recovery
This study tests if adding acupuncture before and after knee replacement surgery helps reduce pain and improve recovery. It may be an option for people having planned knee replacement for osteoarthritis.
Pavia, PaviaAges 18 years+ - NCT07123987Recruiting
Ear nerve stimulation for post-shingles pain
This study tests a gentle, non-invasive device that stimulates a nerve in your ear to see if it can reduce lingering pain after shingles. It may be a good option if you have had persistent nerve pain for at least 3 months.
Cairo, Giza GovernorateAges 35–65 - NCT07127380Recruiting
Comparing two types of spine surgery for disc-related low back pain
This study compares two different surgery methods (Mini-TLIF and MIDLIF) for treating low back pain caused by worn-out discs in the lower back. The goal is to see which one offers better recovery, fewer complications, and lower costs.
Lodz, Łódź VoivodeshipAges 18 years+ - NCT07128030Recruiting
Moderate exercise for pain in breast cancer survivors
This study tests whether moderate exercise (like brisk walking) can help reduce pain and sensitivity in breast cancer survivors. It's designed for women who have finished their main treatments and still have discomfort in their arm or shoulder on the side where they had surgery.
MadridAges Any age - NCT07129811Recruiting
Nerve block for chronic pain syndrome
This trial tests a nerve block injection (stellate ganglion block) to treat complex regional pain syndrome, a chronic pain condition. It may help if your pain is severe and other treatments haven't worked.
Ankara, ÇankayaAges 18–75 - NCT07130084Recruiting
Virtual reality for first-time planned cesarean births
This trial tests if using virtual reality (VR) during a planned cesarean section can help reduce anxiety and improve the birth experience. It is for women having their first planned cesarean and who own a compatible smartphone or tablet.
BathAges 18 years+ - NCT07130760Recruiting
Testing two numbing methods for tooth pain in a back molar
This trial compares two ways to numb a painful lower back molar. If you have a tooth infection that needs a root canal, you may receive one of two injection techniques to see which works better.
Ferrol, A coruñaAges 18 years+ - NCT07130812Recruiting
Blood flow restriction training for rowers with back pain
This study tests whether a special training technique called blood flow restriction can help rowers aged 13-20 with mild or recurring back pain. It involves wearing bands on your legs while rowing, which may help you build strength and recover while reducing pain.
Loma Linda, CaliforniaAges 13–20 - NCT07133139Recruiting
Dry needling for chronic low back pain
This study tests whether a treatment called dry needling (using thin needles on muscle knots) helps people with long-term low back pain tied to muscle tightness. It is for those who have not tried this treatment before and whose main pain is in the lower back.
Pittsburgh, PennsylvaniaAges 20–70 - NCT07134660Recruiting
Comparing two numbing medicines for lung surgery pain
This study compares two types of numbing medicine (liposomal vs. hydrochloride bupivacaine) injected near the ribs during lung surgery. The goal is to see which one provides better pain relief after the operation.
ShanghaiAges 18–80 - NCT07137065Recruiting
A new approach to managing low back pain in primary care
This study tests a program designed to help people with low back pain get better care from their general practitioner. If you have low back pain (with or without leg pain) and haven't seen your doctor for this same problem in the last 3 months, you may be able to join.
Geneva, Canton of GenevaAges 18 years+ - NCT07137715Recruiting
Wellness and recovery for veterans with chronic back or neck pain
This study tests a psychological program to help veterans manage chronic back or neck pain. It aims to improve your wellbeing and daily function through counseling or coaching sessions.
Aurora, ColoradoAges 18 years+ - NCT07139483Recruiting
Preventing chronic phantom limb pain with mirror therapy and brain stimulation
This study tests whether combining mirror therapy (looking at a reflection of your healthy limb) with a gentle brain stimulation technique called tDCS can prevent phantom limb pain from becoming long-lasting. It is for people who recently had a limb amputated and are already starting to feel phantom pain.
Raanana, IsraelAges 18 years+ - NCT07141108Recruiting
Using a digital tool to track chronic pain and improve quality of life
This trial tests a digital tool that helps you track your pain and activity level. The goal is to see if using the tool can improve your quality of life. You would use a smartphone or tablet app and share updates with your primary care team.
Malmö, Skåne CountyAges 18 years+ - NCT07144436Recruiting
Pain after stroke: brain scan and treatment study
This trial tests whether a special kind of brain scan (called tAN-fMRI) can help understand and treat pain that happens after a stroke. You may qualify if you had a stroke at least 6 months ago and are between 18 and 80 years old.
Charleston, South CarolinaAges 18–80 - NCT07147764Recruiting
Pain education plus physiotherapy for jaw pain
This trial compares two treatments for long-lasting jaw or face pain: physiotherapy alone versus physiotherapy combined with education about how pain works. It aims to find which approach helps more.
Istanbul, KavacikAges 18–65 - NCT07148388Recruiting
Accelerated TMS for nerve pain relief
This trial tests a faster type of brain stimulation (AiTBS) for people with nerve pain. If you have had nerve pain for at least three months and it is moderately severe, this non-invasive treatment might help reduce your pain.
HangzhouAges 18 years+ - NCT07150702Recruiting
Close follow-up for low back pain
This study is testing whether closer follow-up care helps people with long-term low back pain feel better faster. You'll receive a standard physical therapy program but with more frequent check-ins to see if extra support improves your recovery.
Istanbul, FatihAges 18–65 - NCT07151248Recruiting
Earlobe stimulation for Gulf War veterans with chronic pain
This trial tests a mild electrical stimulation device (called CES) on the earlobe to see if it can reduce pain and improve brain function in veterans with Gulf War Illness. You will have brain scans and answer questions about your symptoms.
Atlanta, GeorgiaAges 40–80
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,751 recruiting pain medicine studies from the U.S. registry right now, out of 6,825 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.