Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07332390Recruiting
Exercise study for chronic non-specific low back pain
This study compares two types of exercise programs—moderate load eccentric core exercises and Pilates—to see which is more effective for people with long-lasting low back pain that isn't caused by a specific medical condition.
Islamabad, Punjab ProvinceAges 18–45 - NCT07332377Recruiting
mHealth pain self-management for cancer survivors
This study tests a mobile health (smartphone) program that helps you manage pain after cancer treatment. It’s for people who have finished treatment and are in remission but still have cancer- or treatment-related pain.
Richmond, VirginiaAges 18 years+ - NCT07332845Recruiting
Neck and hamstring therapy for chronic pain
This trial tests a special exercise technique that combines shoulder blade and pelvis movements to see if it helps people with long-term neck pain and tight hamstrings.
Karachi, SindhAges 18–40 - NCT07333417Recruiting
Rigid taping for acromioclavicular joint degeneration
This study tests whether a special rigid tape applied to the shoulder can reduce pain and improve function in people with acromioclavicular (AC) joint degeneration. The AC joint is where your collarbone meets the top of your shoulder blade, and this condition can cause pain and stiffness.
Ankara, AnkaraAges 18–65 - NCT07334288Recruiting
Numbing injection for pain relief after lower back surgery
This study tests a numbing injection near the spine (retrolaminar block) to reduce pain after lower back surgery with hardware. It could help you use less pain medicine and recover more comfortably.
Santiago, Santiago MetropolitanAges 18–80 - NCT07334756Recruiting
Mobilization therapy for long-term low back pain
This study tests gentle back movements (not forceful adjustments) to see if they help relieve low back pain that has lasted more than 3 months. If you have low back pain without leg pain, this may be an option to try.
Islamabad, Punjab ProvinceAges 18–45 - NCT07335718Recruiting
Radiofrequency therapy for low back pain from disc herniation
This trial tests if a type of radiofrequency treatment (TECAR therapy) can reduce pain and improve function and quality of life for people with low back pain caused by a herniated disc. It involves an exercise program along with the treatment.
AnkaraAges 20–60 - NCT07335913RecruitingPhase 1
Testing SBS-147 in healthy adults for safety
This study tests a new drug, SBS-147, in healthy adults to see if it's safe and how the body processes it. It may help find the right dose for future studies in people with certain conditions.
Cypress, CaliforniaAges 18–55 - NCT07336082Recruiting
Sensory training vs. exercise for awake teeth clenching
This study compares two non-drug treatments—sensory training and exercise therapy—to help people who clench or grind their teeth while awake. It aims to reduce jaw pain and improve daytime function.
AydinAges 18–45 - NCT07336264Recruiting
Understanding acute pain in children
This study looks at how children and teens experience pain after surgery or during a bone marrow transplant. It aims to better understand acute pain, which is short-term pain that goes away as the body heals.
Washington D.C., District of ColumbiaAges 6–21 - NCT07336537Recruiting
Testing talk-based data collection software for chronic pain
This study tests easy-to-use talk-based software to collect health information from people with chronic pain. It may help researchers learn if tools like these are helpful for managing pain at home or in a lab.
Cambridge, MassachusettsAges 18 years+ - NCT07338006Recruiting
Chest wall reconstruction study
This trial studies patients who need surgery to rebuild part of their chest wall after a defect. It looks at how well different reconstruction methods work, especially for larger defects that can't be simply closed.
Lahore, Punjab ProvinceAges 18 years+ - NCT07338045Recruiting
Baduanjin exercise for chronic low back pain in office workers
This trial tests whether an eight-week Baduanjin exercise program can reduce chronic low back pain and improve daily function in office workers. Baduanjin is a gentle mind-body practice that involves slow movements and breathing, and it may help relieve pain caused by prolonged sitting.
Xi'an, ShaanxiAges 20–55 - NCT07338292Recruiting
Virtual reality for pain and anxiety in urology procedures
This study tests if using virtual reality can reduce pain and anxiety during outpatient urology procedures like circumcision, prostate biopsy, or flexible cystoscopy. If you are having one of these procedures for the first time, you may be able to participate.
PadovaAges 18–99 - NCT07339631RecruitingPhase 1
Sodium Aescinate for Chronic Low Back Pain in Adults
This study tests an injectable medication called sodium aescinate (derived from horse chestnut) for people with chronic low back pain. It aims to see if it helps reduce pain and is safe to use.
Xi'an, ShaanxiAges 18–65 - NCT07342777Recruiting
Exercise for Pain Relief in Multiple Sclerosis
This study tests whether exercise can help reduce pain in people with multiple sclerosis. If you have MS and moderate to severe pain, you may be asked to participate in a supervised exercise program.
Aarhus, DenmarkAges 18 years+ - NCT07344090Recruiting
Using a decision tool to manage fever and pain in children
This trial tests a decision-making system to help parents manage fever and acute pain in young children. It's for children aged 3 months to 5 years who need paracetamol for fever or pain.
Florence, ItalyAges 3 months–5 years - NCT07344467Recruiting
Melatonin vs. Pregabalin for pain and anxiety after spine surgery
This trial compares two medications—melatonin and pregabalin—to see which works better at reducing pain and anxiety after spine surgery. It aims to find a safer, effective option for recovery.
Tanta, El-GharbiaAges 21–60 - NCT07345221Recruiting
Cold therapy for nerve pain from breast cancer chemo
This trial tests whether cooling the hands and feet during taxane chemotherapy can prevent or reduce nerve pain (peripheral neuropathy). It may help breast cancer patients who have not had nerve problems before.
IstanbulAges 18 years+ - NCT07677969Recruiting
Arm loss, balance, pain, and daily life study
This study looks at how the percentage of arm loss affects balance, neck and back pain, daily activities, and reaction time in people with one arm amputated who use a myoelectric or bionic hand. It may help understand how to improve care and rehabilitation.
AnkaraAges 18–65 - NCT07677631Recruiting
Emotional allodynia in fibromyalgia: a questionnaire study
This study compares how people with fibromyalgia and those with other long-term pain conditions experience emotional pain (like feeling hurt by emotions). You will fill out a questionnaire about emotional sensitivity. The goal is to see if emotional allodynia (pain from emotions) is more common in fibromyalgia.
BariAges 18 years+ - NCT07679074Recruiting
Samphire guided care program for women's mood and brain fog
This 12-week program tests a mobile app and gentle brain stimulation device designed to help women manage mood and thinking problems linked to their menstrual cycle, perimenopause, or menopause. It aims to improve day-to-day well-being, work productivity, and overall quality of life.
San Francisco, CaliforniaAges 18–65 - NCT07566663Recruiting
Pain Relief Before Gallbladder Removal Surgery
This study tests whether a pain-relief medication called Anrikefon, given before laparoscopic gallbladder removal surgery, helps reduce pain after the procedure. Laparoscopic surgery uses small cuts and a camera, so it's less invasive than open surgery.
Beijing, Beijing MunicipalityAges 18–65 - NCT07679295Enrolling by invitation
Port needle change: pain, anxiety, and satisfaction
This trial tests if using a stress ball during port needle changes can help reduce pain and anxiety in cancer patients. It aims to improve comfort and patient satisfaction.
SanliurfaAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.