Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,764 recruiting studies in this area right now.
By phase
- Not applicable3,111
- Phase 4251
- Phase 2144
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University97
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University32
- Tanta University30
- Foundation University Islamabad26
- Mayo Clinic26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California158
- New York80
- Massachusetts68
- Florida65
- Texas52
- Ohio48
- Maryland42
- Minnesota41
- Illinois38
- North Carolina38
Recruiting studies3,763 total
- NCT07511842Recruiting
Keeping Your Knee Still After Surgery to Reduce Pain
This study tests whether keeping your knee immobilized (held still) for 72 hours after knee replacement surgery helps reduce pain. Researchers will compare this approach to standard care to see if it makes recovery easier.
Sherbrooke, QuebecAges 18 years+ - NCT07512141Recruiting
Single vs. Double Drains After Breast Cancer Surgery
This study compares using one drain versus two drains to collect fluid after breast cancer removal surgery. The goal is to see which approach works better and causes fewer problems during recovery.
Karachi, SindhAges 18–70 - NCT07512752Recruiting
Preoperative Stress and Confusion After Orthopedic Surgery
This study examines how anxiety before major joint surgery (hip or knee) affects confusion and delirium after surgery in adults 65 and older. Understanding this connection may help doctors better manage patients' emotional and mental health around surgery.
ElâzığAges 65 years+ - NCT07513350Recruiting
Exercise and anti-fibrotic treatment for frozen shoulder
This study tests whether exercise combined with an anti-fibrotic medication (a drug that reduces scar tissue) helps people with frozen shoulder regain shoulder movement. Frozen shoulder causes stiffness and pain that limits your ability to move your arm.
IstanbulAges 18 years+ - NCT07514546Recruiting
Laughter yoga video for menstrual cramp relief
This study tests whether watching a video of guided laughter exercises can reduce the pain of menstrual cramps. Researchers believe laughter and breathing may help ease discomfort during your period.
Konya, KaratayAges 18–24 - NCT07516327Recruiting
Cold and Compression Therapy After Rotator Cuff Surgery
This study tests whether using cold therapy and compression after rotator cuff repair surgery helps reduce pain and swelling during recovery. You would receive this special treatment as part of your regular physical therapy at a specific Ochsner location.
Kenner, LouisianaAges 35 years+ - NCT07523399Recruiting
Joint Health and Balance in Adults with Hemophilia A
This study looks at how hemophilia A affects joint health, balance, and quality of life in adults. Researchers will assess your joints and balance to understand the relationship between joint damage and everyday function.
VanAges 18–65 - NCT07523802Recruiting
Managing pain after gum graft surgery with two methods
This trial tests two different ways to protect and manage pain in the mouth after a gum graft surgery. You would compare a product called Ora-Aid with a custom acrylic stent (a protective cover) to see which helps with healing and reduces discomfort better.
CairoAges 18 years+ - NCT07523906Recruiting
Exercise therapy for chronic lower back pain in young adults
This study compares two types of exercise programs for chronic mechanical lower back pain: lumbar stabilization exercises (focused on core strength) versus muscular chain therapy (full-body movement patterns). You'll participate in one of these exercise programs to see which helps reduce your pain more effectively.
IslamabadAges 18–30 - NCT07524075Recruiting
Muscle Energy Technique for Neck Pain and Movement
This study tests whether a hands-on physical therapy technique called muscle energy technique can reduce neck pain and improve how far you can move your neck. If you have neck pain that's lasted at least 4 weeks with no clear medical cause, this trial may help you.
Istanbul, AtaşehirAges 18–65 - NCT07524231Recruiting
Laughter Yoga Effects on Health and Well-being
This study tests whether laughter yoga—guided exercises that combine laughter with breathing—can improve health outcomes. Researchers will measure how it affects participants' physical and mental well-being over time.
ElâzığAges 18 years+ - NCT07524270Recruiting
Testing a supplement for period pain and PMS symptoms
This study tests a product called Effera to see if it helps reduce menstrual cramps, pain, and premenstrual symptoms like mood changes and bloating. You'll track your symptoms and complete online surveys over several weeks.
San Francisco, CaliforniaAges 18–40 - NCT07524387Recruiting
Nerve blocks for better leg strength after knee replacement
This study compares two types of numbing injections (nerve blocks) used during knee replacement surgery to see which one helps your thigh muscle recover strength faster. Both are standard care options; the trial tests which works better for early movement after surgery.
Ichinomiya, Aichi-kenAges 20 years+ - NCT07524673Recruiting
Comparing two nerve blocks for chest surgery pain
This study tests two different numbing techniques (nerve blocks) to see which one works better for pain relief after minimally invasive chest surgery. Both methods inject medicine near nerves to reduce post-surgery pain.
Sivas, MerkezAges 18 years+ - NCT07524751Recruiting
Cultural Pain Management Program for Indigenous People
This study tests a pain management program designed specifically for American Indian and Alaska Native communities. If you have chronic pain (lasting over 3 months), this program teaches coping strategies that respect your culture and background.
Yakima, WashingtonAges 18 years+ - NCT07525557Recruiting
Understanding Fear and Disability in Long-Term Neck Pain
This study explores how fear of movement, pain, and daily difficulties relate to each other in people with chronic neck pain lasting 3+ months. Understanding these connections may help improve future treatment approaches.
Samsun, SamsunAges 18 years+ - NCT07525986RecruitingPhase 4
Pain control after laparoscopic colon surgery using a button-press system
This trial tests a new pain medication (anrikefon) that patients can control themselves by pressing a button after laparoscopic colon surgery. The goal is to see if it works better or safer than standard pain relief, especially for patients whose nerve blocks alone don't fully control pain.
Beijing, Beijing MunicipalityAges 18–75 - NCT07526012Recruiting
Stretching techniques for buttock pain from pinched nerve
This study compares two stretching methods to treat piriformis syndrome, a condition where a muscle in your buttock pinches a nerve. The trial tests whether one stretching approach works better than the other for reducing pain.
Islamabad, Punjab ProvinceAges 20–55 - NCT07528482Recruiting
Reflexology and cold therapy for chest tube removal pain
This study tests whether foot massage (reflexology) and cold application can reduce pain when chest tubes are removed after heart bypass surgery. Researchers want to see if these complementary techniques help manage discomfort during this procedure.
AnkaraAges 18 years+ - NCT07528807Recruiting
Exercise, Pain Beliefs, and Activity in Musculoskeletal Pain
This study explores how exercise, your beliefs about pain, and your daily activity patterns affect musculoskeletal pain (pain in muscles, joints, or bones). Researchers want to understand these connections better to potentially improve pain management and help people stay active.
IstanbulAges 18–65 - NCT07528833Recruiting
Mindfulness stress reduction for chronic back pain
This study tests whether a mindfulness-based stress reduction course can help reduce back pain. Mindfulness teaches you to focus on the present moment and manage stress, which may help ease chronic pain in your lower or mid-back.
TampereAges 18–64 - NCT07532070Recruiting
Exercise and Therapy for Chronic Pain and Sleep Problems
This study tests whether exercise, talk therapy for sleep problems, or both together can help people with long-term back, hip, or knee pain who also struggle with sleep. You'll attend video appointments and try one of these approaches for several weeks.
San Antonio, NevadaAges 18 years+ - NCT07533409Recruiting
Touch and Pain Sensitivity in Children with Writing Difficulties
This study measures how sensitive children are to touch and pain, and tests their hand strength. Researchers want to understand if children who struggle with writing have different sensory abilities than other children their age.
EdirneAges 6–12 - NCT07533669Recruiting
Sensory room visit before kidney transplant surgery
This study tests whether spending time in a calming sensory room before kidney transplant surgery helps reduce pain, anxiety, and sleep problems. You would visit a specially designed room with soothing sights, sounds, and textures before your operation.
SakaryaAges 18 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,764 recruiting pain medicine studies from the U.S. registry right now, out of 6,842 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.