Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,576 recruiting studies in this area right now.
By phase
- Not applicable2,951
- Phase 4240
- Phase 2131
- Phase 3102
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University60
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California152
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,576 total
- NCT07558226Recruiting
Pain management approaches for robotic kidney removal surgery
This study tests different combinations of pain medications during robotic surgery to remove all or part of a kidney due to cancer. The goal is to find the best way to control pain while keeping you comfortable and allowing you to go home the same day or next day.
Barcelona, BARCELONAAges 18 years+ - NCT07555314Recruiting
Outpatient Catheter for Lidocaine Pain Treatment
This trial tests using a special catheter (thin tube) to deliver lidocaine—a numbing medication—to treat chronic pain on an outpatient basis. Researchers want to see if this approach helps manage long-term pain effectively.
WarsawAges 18 years+ - NCT07553533Enrolling by invitation
Temporary Nerve Stimulation for Headache Relief
This trial studies a temporary nerve-stimulation device placed near the back of your head to treat chronic headaches. The device sends mild electrical pulses to help reduce headache pain over 60 days, and your doctor has already decided this treatment is right for you as part of your regular care.
New Haven, ConnecticutAges 18 years+ - NCT07557108Recruiting
Nerve Blocks to Improve Recovery After Heart Surgery
This study tests whether special numbing injections around nerves in the chest wall (fascial plane blocks) help patients recover better and have less pain after open-heart surgery. The goal is to see if this technique improves how you feel and function in the days after your operation.
Ordu, AltinorduAges 18–70 - NCT07553143Recruiting
Melatonin before gallbladder removal surgery
This study tests whether taking melatonin (a natural sleep hormone) before elective gallbladder removal surgery helps patients recover better and feel less pain or discomfort afterward. Melatonin may help reduce stress on the body during surgery.
Dhaka, Dhaka DivisionAges 18–60 - NCT07558278RecruitingPhase 4
LINQ procedure vs standard care for sacroiliac joint pain
This study compares a new procedure called LINQ—which stabilizes the sacroiliac joint (the joint where your spine connects to your pelvis)—against standard pain management for chronic sacroiliac joint pain. The trial tests whether this procedure reduces pain and disability better than medications and physical therapy alone.
Shenandoah, TexasAges 21 years+ - NCT06644261RecruitingPhase 4
Comparing two methods of nerve block for pelvic pain
This study compares two ways to give a pudendal nerve block—one through the vagina, one through the buttock with X-ray guidance—to see which works better for women with pudendal neuralgia (nerve pain in the pelvic area). It may help find a more effective and comfortable treatment option.
Louisville, KentuckyAges 18 years+ - NCT06740903RecruitingPhase 2/Phase 3
Comparing two drugs for pain control in gallbladder surgery
This study compares two medications, dexmedetomidine and lignocaine, to see which works better for pain management during and after laparoscopic gallbladder removal. It may help improve comfort and recovery for people having this surgery.
Sahiwal, Punjab ProvinceAges 20–70 - NCT06393608RecruitingPhase 2
Epsom salt compresses for postpartum perineal relief
This study tests whether warm compresses with Epsom salt can soothe pain and swelling in the vaginal area after childbirth. It's for mothers who had a vaginal delivery and are staying in one of the three participating hospitals.
Chicoutimi, QuebecAges 18 years+ - NCT06741696Recruiting
Saline rinsing after wisdom tooth removal
This trial tests whether using saline (salt water) at different temperatures after wisdom tooth surgery helps with healing and pain. It could help you recover more comfortably.
Rawalpindi, Punjab ProvinceAges Up to 59 years - NCT07543796RecruitingPhase 2
Pain Relief After Hip Replacement Surgery
This study tests whether a new pain medication called TRD205 works well and is safe for people recovering from hip replacement surgery. If it works, it could offer better pain control after your operation.
Guangzhou, GuangdongAges 18–80 - NCT07547215Recruiting
TRAQ Minimally Invasive Sacroiliac Joint Fusion Study
This study tests a minimally invasive surgical procedure called TRAQ to treat chronic sacroiliac joint (SIJ) pain—a type of lower back and buttock pain. The procedure may help if you've had pain for at least 6 months that didn't improve with non-surgical treatments and have already benefited from diagnostic joint injections.
Tucson, ArizonaAges 21 years+ - NCT07548567Recruiting
Nerve Block to Reduce Pain During Below-Knee Fracture Surgery
This study tests a nerve-blocking injection (numbing medicine around the femoral artery nerve in your groin area) to help reduce pain and blood pressure changes during below-knee fracture surgery when a tourniquet (pressure cuff) is used. The goal is to see if this approach makes surgery more comfortable and safer.
AthensAges 18 years+ - NCT07544914Recruiting
Magnetic Stimulation for Elbow and Wrist Chronic Pain
This study tests whether a non-invasive magnetic therapy applied to the skin can reduce chronic pain from tennis elbow, golfer's elbow, or carpal tunnel syndrome. The treatment uses magnetic pulses to stimulate nerves and may help relieve pain without medication or surgery.
Winnipeg, ManitobaAges 18 years+ - NCT07544108Recruiting
Understanding What Affects Neck Pain Recovery
This study helps researchers understand which patients with long-term neck pain recover better and why. By learning more about your neck pain and how it affects your daily life, the study may help doctors predict outcomes and improve treatment.
Kütahya, KütahyaAges 18–65 - NCT07547774Recruiting
Sleep Quality Before Breast Surgery and Recovery Outcomes
This study examines how well you sleep before breast cancer surgery and whether it affects your recovery afterward. Researchers will ask about your sleep habits and track your healing to understand the connection.
Ankara, YenimahalleAges 18–70 - NCT07547618Recruiting
Pain Management in Recovery Room After Surgery
This study observes how much pain medication patients need right after surgery while they're in the recovery room. Researchers want to understand pain patterns to help improve comfort for future surgical patients.
Ankara, YenimahalleAges 18 years+ - NCT07549685Enrolling by invitation
Music Therapy to Help Breast Cancer Patients During Chemotherapy
This study tests whether music therapy can help women with breast cancer feel better during chemotherapy after surgery. Researchers will see if listening to or participating in music sessions improves quality of life and reduces stress during treatment.
AlessandriaAges 25–75 - NCT07547566Recruiting
TECAR Therapy vs. Cycling for Athletic Recovery
This study compares two recovery methods—TECAR therapy (a heating treatment) and cycling—to see which helps young athletes recover better after jumping exercises. The goal is to understand which approach reduces fatigue and helps athletes bounce back faster.
Córdoba, CórdobaAges 18 years+ - NCT07544732Recruiting
Tape comparison for heel pain relief
This study tests two types of taping methods to reduce heel pain caused by plantar fasciitis. You'll wear special tape on your foot for a few weeks to see which method works better for your pain and movement.
Islamabad, Punjab ProvinceAges 19–44 - NCT07551323Recruiting
Myofascial Release vs. Pilates for Chronic Low Back Pain
This study compares two hands-on treatment approaches—myofascial release (deep tissue massage) and Pilates exercises—to see which works better for chronic low back pain that isn't caused by nerve damage. If you have persistent lower-back pain, this trial might help you find relief through one of these therapies.
Istanbul, IstanbulAges 18–45 - NCT07550543Recruiting
PEMF Therapy for Chronic Shoulder Pain
This study tests whether pulsed electromagnetic field (PEMF) therapy—a treatment using magnetic pulses—can reduce chronic shoulder pain and improve how well your shoulder works. You would receive this therapy at a rehabilitation center over several weeks.
Constanța, TechirghiolAges 18–70 - NCT07547371Recruiting
Aromatherapy and Digital Anesthesia for Dental Anxiety in Children
This study tests whether aromatherapy (calming scents) and digital anesthesia (numbing technology) can help reduce anxiety and pain when children need a baby molar removed. The goal is to find gentler ways to keep children comfortable during dental procedures.
Istanbul, IstanbulAges 6–12 - NCT07545850Enrolling by invitation
Virtual Reality Glasses to Reduce Pain During IUD Insertion
This study tests whether wearing virtual reality glasses during an IUD insertion procedure can help reduce pain and anxiety. You would wear the glasses during the procedure to see if they help you feel calmer and experience less discomfort.
MalatyaAges 18–49
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,576 recruiting pain medicine studies from the U.S. registry right now, out of 6,474 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.