Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07190495RecruitingPhase 4
Ginger to prevent nausea after gallbladder surgery
This trial tests if taking ginger can help prevent nausea and vomiting after gallbladder surgery. It might be an option for people who want a natural remedy to feel better after their operation.
Nabeul, Nabeul GovernorateAges 18 years+ - NCT07186634RecruitingPhase 4
Surgery recovery medicine platform trial
This trial tests different medicines to improve recovery after surgery. It includes adults having surgery that lasts at least 2 hours and requires an overnight hospital stay.
Melbourne, VictoriaAges 18 years+ - NCT06523842Enrolling by invitation
Arabic version of a muscle pain questionnaire test
This study tests a translated questionnaire that measures muscle and joint pain in the neck, shoulders, back, and arms. It asks Arabic-speaking workers to fill out the form to see how well it works.
Dokki, Giza GovernorateAges 18–60 - NCT07185594RecruitingPhase 2/Phase 3
Study of a new pain drug after abdominal surgery
This trial tests a new medication called HRS-2129 for managing pain after abdominal surgery. It is for adults who will have moderate to severe pain after their operation, and aims to see if the drug can help control that pain safely.
Zhengzhou, HenanAges 18 years+ - NCT06513208RecruitingPhase 4
Ketorolac for pain after lower back fusion surgery
This trial tests if a non-steroidal anti-inflammatory drug (NSAID) called ketorolac can help reduce pain after lower back fusion surgery. It is for people who are having elective surgery to fuse one or two bones in their lower back.
Towson, MarylandAges 18–85 - NCT07182461Recruiting
Taping and exercises for upper crossed syndrome
This study tests if wearing a special tape and doing corrective exercises can help with neck and shoulder posture and muscle balance. It might be a good option if you have poor posture called upper crossed syndrome.
Taichung, BeitunAges 20–35 - NCT05597683Recruiting
Nerve block for pain after major abdominal cancer surgery
This trial studies whether a targeted nerve block (called a quadratus lumborum block) can improve pain control after cytoreductive surgery and heat-based chemotherapy put into the abdomen (CRS and HIPEC). It may help some people use less rescue pain medicine and feel more comfortable during recovery.
SeoulAges 19 years+ - NCT07354451Recruiting
Pelvic nerve treatment for period pain
This trial tests a gentle hands-on technique to ease severe period pain by targeting pelvic nerves. It may help if you have very painful periods without another medical cause.
SialkotAges 18–30 - NCT07309731Recruiting
Hot vs. cold radiofrequency for chronic low back pain from facet joints
This trial compares two types of radiofrequency treatment (cooled vs. thermal) to see which works better for chronic pain coming from the small joints in your lower back. It is for people who have had back pain for at least 3 months and haven't gotten enough relief from usual treatments like pain medicine or physical therapy.
Zagazig, ElsharqyaAges 30–70 - NCT06819748Recruiting
Numbing medicine mix for less pain after gallbladder surgery
This trial tests a mixture of numbing medicines (ropivacaine cocktail) injected into the surgery area to reduce pain after gallbladder removal. It's for people having same-day laparoscopic surgery and aims to help you recover with less pain.
Chengdu, SichuanAges 18–70 - NCT07584915Enrolling by invitationPhase 4
Pain Relief Method Comparison for Knee Replacement Surgery
This study tests a new way to deliver pain medication during and after knee replacement surgery. Researchers compare injecting a long-acting numbing medicine (EXPAREL) directly into the knee joint versus spreading it through the surgical area, to see which method works better for pain control.
Los Angeles, CaliforniaAges 18 years+ - NCT06853431RecruitingPhase 4
Pre-surgery calming medicine for children ages 1 to 6
This study tests a combination of two medicines (dexmedetomidine and esketamine) given as a nasal spray to help children relax before surgery. The goal is to find the best dose that works well with the least side effects.
Wenzhou, ZhejiangAges 1–6 - NCT07131579Enrolling by invitation
Dexmedetomidine via IV for knee surgery pain
This trial tests adding a medicine called dexmedetomidine to the numbing IV used during knee surgery. It aims to see if it provides better pain relief after surgery under spinal anesthesia.
Al MansurahAges 18–60 - NCT07130747Recruiting
Comparing massage techniques for c-section scar recovery
This study compares two types of gentle manual therapy (myofascial release and deep friction massage) to see which works better for reducing pain, helping the belly recover, and improving a C-section scar. It may be a good option if you're between 30–45, had a C-section over 6 months ago, and still have scar or pelvic pain.
AlexandriaAges 30–45 - NCT07273097Recruiting
Ankle muscle fatigue and walking in ankle instability
This trial studies how tired ankle muscles affect walking in people with chronic ankle instability. It compares their walking patterns to healthy people to understand if fatigue makes ankle issues worse.
LjubljanaAges 18–45 - NCT06857760Recruiting
Soothing methods after spine surgery for nausea and thirst
This study tests three different methods to help reduce nausea, thirst, and discomfort after lower back disc surgery. It compares simple soothing techniques (like cold packs or mouth care) to see which works best for a quicker, more comfortable recovery.
AmasyaAges 18 years+ - NCT07275983Recruiting
Knee replacement recovery: spinal vs. general anesthesia
This study looks at recovery after total knee replacement surgery. It compares people who had spinal anesthesia (numbing the lower body) to those who had general anesthesia (being fully asleep) to see which group recovers better.
StrasbourgAges 18 years+ - NCT05905146Recruiting
Personalized opioid plan to shorten treatment time
This trial tests whether a personalized medication plan can help patients with short-term, non-cancer muscle or joint pain need strong opioid medicine for a shorter time. It’s aimed at improving how long treatment lasts while still managing pain.
LilleAges 18 years+ - NCT06853327Enrolling by invitationPhase 2
Ketorolac for pain during IUD insertion
This study tests if a pain-relief medicine, ketorolac, helps reduce pain when getting an IUD placed. It might be an option if you are planning to have an IUD inserted.
Hillsborough, North CarolinaAges 18 years+ - NCT07360847Recruiting
Understanding recovery from rotator cuff shoulder pain with non-surgical care
This study looks at people with rotator cuff shoulder pain who are starting non-surgical treatments like physical therapy. It aims to understand which factors help people get better, so doctors can provide more personalized care.
LimerickAges 18 years+ - NCT06565377Recruiting
Pre-surgery program for knee replacement patients
This trial tests a program of exercise, education, and support to help you prepare for knee replacement surgery. It aims to improve your recovery and quality of life.
Geel, AntwerpenAges 18 years+ - NCT07093905Recruiting
Comparing two anesthetics for rotator cuff repair surgery
This study compares two types of anesthesia (numbing medicine) for rotator cuff repair surgery. It will help find which method works better for pain control and recovery.
MarseilleAges 18 years+ - NCT06858917Recruiting
Block comparison for tailbone pain
This trial compares two types of nerve blocks to treat long-term tailbone pain. It tests whether a block near the tailbone or one in the lower back works better for people who haven't found relief from other treatments.
Istanbul, BaşakşehirAges 18–65 - NCT07092878Recruiting
Chamomile and L-theanine drink for period pain
This study tests whether a beverage made from chamomile and L-theanine (a natural ingredient found in tea) can help reduce period pain in young women. It may be a good option if you have moderate to severe cramps and want a natural approach.
Kampar, PerakAges 18–30
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.