Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07013695Recruiting
Virtual reality to reduce sedation in orthopedic surgery
This trial tests if watching virtual reality during regional anesthesia for planned arm or leg surgery can lower the need for calming medicine. It may help you feel more relaxed without as many drugs.
ÉvreuxAges 18 years+ - NCT07747350Recruiting
Laser vs pain pills for braces pain in Malay women
This study compares a low-level laser treatment with standard painkillers to see which works better for reducing pain from getting braces. It is for Malay women aged 18-33 who have never had braces and are generally healthy.
Kota Bharu, KOTA BHARUAges 18–33 - NCT07748520Recruiting
Nesting during shots for newborns after cesarean birth
This study tests whether placing newborns in a cozy 'nest' during their first shot after a cesarean birth reduces pain and stress and improves breastfeeding. It may help your baby feel more comfortable and support a good start to breastfeeding.
Darıca, KocaeliAges Up to 30 minutes - NCT07555067Enrolling by invitation
Robotic Knee Replacement Surgery Comparison
This trial compares two different robotic systems used during knee replacement surgery for knee arthritis (wear and tear). The study helps doctors understand which robotic system may provide better results.
Bydgoszcz, Kuyavian-Pomeranian VoivodeshipAges 18 years+ - NCT07011069Recruiting
Comparing two pain blocks for lung surgery recovery
This trial tests two nerve-block methods to see which provides better pain control after minimally invasive lung surgery (VATS). If you qualify, you would receive one of the blocks to help reduce pain and possibly speed recovery.
Bursa, NiluferAges 18–80 - NCT06751160Recruiting
Dry needling vs. soft tissue massage for tight hamstrings
This study compares two treatments—dry needling and soft tissue massage—to see which works better for relieving tight hamstring muscles in people with low back pain.
Lahore, Punjab ProvinceAges 20–40 - NCT07010003Recruiting
Ear acupressure for anxiety and pain during heart surgery
This trial tests whether small ear acupressure beads can help reduce anxiety and pain in adults having planned heart surgery. The beads are placed on specific ear points and are easy to use.
StuttgartAges 18 years+ - NCT07253012Recruiting
AI pain relief assistant for surgery patients
This trial tests a computer system that helps manage pain during surgery. It may be an option if you are having a planned surgery lasting between 2 and 4 hours.
SantiagoAges Any age - NCT07002983Recruiting
Shoulder exercises to help after mastectomy
This study is testing whether special exercises that retrain how you control your shoulder muscles can help reduce pain and improve movement after mastectomy. It is for women who had breast cancer surgery in the last few months and are now having shoulder problems.
GizaAges 40–55 - NCT07746284Enrolling by invitation
Understanding knee osteoarthritis through computer modeling
This study looks at how knee osteoarthritis pain works and aims to build a computer model to better understand it. By joining, you may help doctors improve future treatments for chronic knee pain.
Herndon, VirginiaAges 18–99 - NCT07743684Recruiting
Jaw joint wash and meloxicam injection for jaw joint problems
This trial tests a treatment for people with jaw joint pain or clicking. It combines a jaw joint wash (arthrocentesis) with an injection of an anti-inflammatory medicine (meloxicam) to see if it helps relieve symptoms. This may be an option if other treatments like mouth splints haven't worked.
BaghdadAges 18 years+ - NCT07001449Recruiting
Pain education for chronic muscle or joint pain
This study tests a type of pain education that focuses on communication to help people with long-term muscle or joint pain. It aims to see if learning about pain in a new way can help reduce symptoms and improve quality of life.
Lamia, Central GreeceAges 18–65 - NCT06083597Enrolling by invitation
Developing a pelvic pain questionnaire for women
This study aims to develop a new questionnaire to better understand and measure chronic pelvic pain in women, especially when it's linked to enlarged pelvic veins. You will be asked to take part in interviews and fill out surveys to help create a tool that reflects your experience.
New York, New YorkAges 18–60 - NCT06714279RecruitingPhase 1
Pain relief methods for gallbladder surgery
This trial compares two ways to reduce pain after laparoscopic gallbladder removal: one uses a nerve block during surgery and the other uses local anesthetic inside the abdomen. The goal is to find which approach provides better pain relief.
DublinAges 18 years+ - NCT06996691Recruiting
Comparing two nerve blocks for lung surgery pain
This study compares two types of nerve blocks to see which one better controls pain after lung surgery. It may help find a better way to manage pain with fewer side effects.
CairoAges 18–70 - NCT07276061Recruiting
Outpatient vs. in-hospital knee replacement recovery study
This study compares recovery after total knee replacement when patients go home the same day versus staying overnight in the hospital. It aims to see if outpatient surgery leads to similar or better recovery.
StrasbourgAges 18 years+ - NCT06994546Recruiting
ArtiBest injection for knee osteoarthritis pain
This trial tests a new hyaluronic acid injection called ArtiBest for people with mild to moderate knee osteoarthritis who haven't gotten enough relief from other treatments like physical therapy or pain pills. It aims to see if the injection can reduce knee pain and improve function.
Kaohsiung CityAges 35–85 - NCT07446556Enrolling by invitation
Exercise program for women with pelvic nerve pain
This trial tests whether a structured exercise program can help women with pelvic nerve pain (pudendal neuralgia). If you have had this pain for at least 3 months and meet the other requirements, you may be able to join.
Martin, SlovakiaAges 18 years+ - NCT07278570Recruiting
Tracking muscle stiffness with MRI during hands-on therapy for low back pain
This study uses a special MRI scan to see if hands-on therapy (manual therapy) helps reduce muscle stiffness and pain in people with chronic low back pain. It aims to find a better way to measure how well this treatment works.
Rochester, MinnesotaAges 18 years+ - NCT05824338RecruitingEarly Phase 1
Testing ropivacaine spinal anesthesia for lower back surgery
This early study tests whether using ropivacaine (a local numbing medicine) in spinal anesthesia is safe and workable for certain lower back operations. If you qualify, it may help doctors refine anesthesia choices for your type of surgery.
New Westminster, British ColumbiaAges 19–80 - NCT06988930Enrolling by invitation
Comparing two treatments for lateral patellar crush syndrome
This trial compares two treatments for lateral patellar crush syndrome: a type of knee surgery called lateral retinacular release versus specific exercises. The goal is to see which approach works better for reducing pain and improving function.
BeijingAges Any age - NCT06984874Recruiting
Nerve block for kids having chest surgery
This study tests a nerve block injection in the back to reduce pain in children aged 6–16 having a specific type of chest surgery (thoracoscopic sympathectomy). It may help them wake up more comfortable and need less pain medicine.
Shibīn al Kawm, MenoufiaAges 6–16 - NCT06709963Recruiting
Brain stimulation for older adults with chronic back or knee pain
This study tests a type of brain stimulation called intermittent theta burst stimulation to see if it can reduce pain and improve thinking in older adults with long-term back or knee pain. The treatment involves a non-invasive procedure that uses magnetic pulses to stimulate the brain.
Hong KongAges 60–85 - NCT06968052Recruiting
Feldenkrais method for forward head posture
This study tests whether the Feldenkrais method (gentle movement lessons) can improve forward head posture in people who sit at a desk for long hours. You may join if you are 18–65, have forward head posture, and spend at least 4 hours daily at a desk.
Istanbul, BuyukcekmeceAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.