Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07444957Recruiting
Safety of a drug-coated balloon for heart artery blockages
This study tests a special balloon coated with a drug called sirolimus to open blocked heart arteries. It may be an option for people with coronary artery disease who need a less invasive treatment.
Vigo, PontevedraAges 18 years+ - NCT07447323Recruiting
Thumb joint position sense study for thumb base arthritis
This study tests how well people with thumb base arthritis can sense their thumb's position. It aims to understand how this sense is affected by the condition and may help improve future treatments.
Ankara, AnkaraAges 25–75 - NCT07452614Recruiting
Predicting pulp treatment success with metabolic markers
This trial tests if a metabolic biomarker can predict how well a vital pulp treatment works for tooth pain caused by deep cavities. It aims to help patients keep their natural teeth instead of needing root canals.
BaghdadAges 16–50 - NCT07452627Recruiting
Comparing Nerve Blocks for Sternotomy Pain
This study compares three different injection techniques (nerve blocks) to reduce pain after heart surgery that cuts through the breastbone. The goal is to find the best way to control pain with fewer side effects.
Bursa, NilüferAges 18–80 - NCT07453576Recruiting
Comparing bleach strengths for root canal retreatment pain
This trial tests if different concentrations of sodium hypochlorite (a disinfectant used in root canals) affect pain and certain natural chemicals in the tooth during root canal retreatment. It may help find the best option to reduce discomfort.
Erzurum, ErzurumAges 18–65 - NCT07453524Recruiting
Understanding what matters to people with chronic pain
This study asks people with chronic pain about their preferences and experiences. Your answers will help doctors understand what matters most to patients like you.
BrusselsAges 18 years+ - NCT07453485Recruiting
Electrical stimulation for Achilles tendon pain and function
This study tests if a brief session of neuromuscular electrical stimulation can reduce pain and improve function in people with Achilles tendon problems, such as midportion or insertional pain, or a healed rupture that happened at least 3 months ago.
Brasília, Federal DistrictAges 18–60 - NCT07451769Recruiting
Testing a new drug target for migraine relief
This trial tests a substance that activates adrenomedullin receptors, which may be a new way to treat migraines. It may help people who have migraines without aura and aren't on preventive migraine medications.
Glostrup MunicipalityAges 18–65 - NCT06705881Recruiting
Shock wave therapy for athletes with jumper's knee
This trial tests if extracorporeal shock wave therapy (a non-surgical treatment using sound waves) can help athletes with patellar tendinopathy, also known as jumper's knee. It is for people who have had pain in the patellar tendon for at least 6 months and are active in jumping sports.
Kırşehir, CenterAges 18–65 - NCT06802419Recruiting
Comparing two types of knee nerve blocks for pain relief after knee surgery
This study compares two types of nerve blocks—one that numbs the front of the thigh and one that adds extra numbing behind the knee—to see which provides better pain relief after arthroscopic knee surgery (like ACL or PCL repair). The goal is to help patients have less pain and recover more comfortably.
CairoAges 21–65 - NCT06805942Recruiting
Embolization for heel pain from plantar fasciitis
This study tests a minimally invasive procedure called embolization to reduce heel pain caused by plantar fasciitis. It blocks tiny blood vessels in the painful area, which may relieve pain and help you walk more comfortably.
Falls Church, VirginiaAges 22–100 - NCT06804434Recruiting
Pain monitor during stomach or liver cancer surgery
This trial tests a device that monitors your pain level during surgery using a special index called the Nociception Level Index. It may help doctors manage your pain better without using too much medicine.
Cluj-Napoca, ClujAges 18 years+ - NCT07440576Recruiting
Numbing shot for pain after prolapse surgery
This trial tests if a numbing injection in the cervix area can reduce pain after minimally invasive prolapse surgery. If you're having this surgery, the study may help determine if the shot makes recovery more comfortable.
Istanbul, IstanbulAges 18 years+ - NCT07435909Recruiting
Bupivacaine for pain after laparoscopic hysterectomy
This trial tests if injecting a numbing medicine called bupivacaine into the abdomen during surgery can reduce pain after a laparoscopic hysterectomy (uterus removal through small cuts). It may help you recover with less discomfort.
Istanbul, GaziosmanpaşaAges 35–75 - NCT07435571RecruitingPhase 2
Treatment of thumb arthritis with a umbilical cord membrane
This trial tests a special membrane made from donated umbilical cord tissue that is placed into the thumb joint to help with pain and function. It aims to be an alternative to surgery for people with early-stage thumb arthritis who haven't gotten better with other treatments.
LyonAges 18–75 - NCT07440069RecruitingPhase 4
Pain relief options for women during active labor
This trial compares the pain relief and effects of tramadol, paracetamol (also known as acetaminophen), and a placebo in women during active labor. It aims to find which option works best and is safest for mothers and babies.
Tegucigalpa, Francisco Morazán DepartmentAges 15–45 - NCT07438522Recruiting
Hand strength exercises for female badminton players
This trial tests two types of hand strengthening exercises (isometric and isotonic) in female competitive badminton players. It aims to see which approach better improves hand and grip performance, which can help with racquet control and power.
Lahore, Punjab ProvinceAges 18–30 - NCT07435168Recruiting
Chest pain and hidden cardiac amyloidosis study
This study looks for signs of a condition called cardiac amyloidosis in people who have chest pain but no blocked heart arteries. It aims to find hidden cases that might be missed with standard tests.
CopenhagenAges 65 years+ - NCT07435337RecruitingPhase 4
Pain medicine study for heart surgery patients
This trial tests two different pain medicines, nalbuphine and fentanyl, to see which one causes fewer changes in blood pressure and heart rate during the placement of a breathing tube for heart surgery.
Rawalpindi, Punjab ProvinceAges 40–60 - NCT07444112Recruiting
Myofascial release for text neck in university students
This trial tests if a hands-on therapy called myofascial release can help university students with text neck (neck pain from looking down at phones). It aims to reduce pain and improve neck function.
Lahore, Punjab ProvinceAges 18–30 - NCT07440836Recruiting
Exercises for separated belly muscle after childbirth
This study compares two types of exercises to help close the gap in your belly muscles that can happen after pregnancy. It may be for you if you have a gap larger than 4cm and certain types of pain.
Lahore, Punjab ProvinceAges 25–40 - NCT07440199Recruiting
Comparing two pain blocks for lung surgery without a breathing tube
This study compares two different pain-blocking techniques for a specific type of lung surgery. It aims to see which one provides better pain relief for patients who are awake during the procedure.
ElâzığAges 18–65 - NCT07442435Recruiting
Reiki for recovery after knee replacement surgery
This study tests whether adding Reiki (a gentle hands-on relaxation therapy) to standard care helps people feel better and recover more comfortably after a first-time knee replacement. It may be a good fit if you are having your first knee replacement, are not on certain medications, and haven't tried energy therapies before.
SinopAges 18 years+ - NCT07440862Recruiting
Pelvic floor exercises and belt for pubic pain in pregnancy
This trial tests if pelvic floor exercises and a support belt work better than either alone for symphysis pubis dysfunction, a condition that causes pain in the front of the pelvis during pregnancy.
Daska KalanAges 25–40
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.