Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,756 recruiting studies in this area right now.
By phase
- Not applicable3,101
- Phase 4252
- Phase 2145
- Phase 3104
- Phase 197
- Phase 2/Phase 335
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University96
- Cairo University62
- Beijing Tiantan Hospital34
- Ain Shams University31
- Tanta University29
- Mayo Clinic28
- Foundation University Islamabad26
- Stanford University24
- VA Office of Research and Development22
- Hacettepe University20
Where studies are running
- California160
- New York81
- Massachusetts68
- Florida63
- Texas52
- Ohio48
- Maryland42
- Minnesota42
- North Carolina38
- Illinois37
Recruiting studies3,755 total
- NCT07720739Recruiting
Adding morphine to a spine block for belly surgery pain
This study tests whether adding a small dose of morphine to a numbing injection near the spine (called erector spinae plane block) provides better pain relief after midline belly surgery. It may help reduce the need for other pain medicines and improve recovery.
SohagAges 18–60 - NCT07714785Recruiting
EEG-guided anesthesia for better recovery after tonsillectomy
This study tests whether using brain-wave monitoring (EEG) during anesthesia with sevoflurane can reduce the amount of pain medicine needed after tonsillectomy and improve how smoothly children wake up. It could help your child have a more comfortable recovery.
Santiago, RegiónAges 2–8 - NCT07640126Recruiting
Acupuncture for cold-sensitive neck pain
This trial tests whether a specific type of acupuncture (three-needle Dazhui plus electroacupuncture) can reduce pain and improve function in people with neck pain caused by cervical spondylosis, especially when the pain is worse in cold weather. It combines a modern diagnosis with traditional Chinese medicine ideas to see if this approach helps more than standard care.
Ho Chi Minh CityAges 3 weeks+ - NCT07662850Recruiting
Rehab after ACL surgery: blood flow training and soft tissue work
This study tests if combining blood flow restriction training with a special manual technique (IASTM) helps reduce pain, build strength, improve knee movement, and lower fear of re-injury after ACL reconstruction. It is for people who are 8 to 16 weeks past surgery and already have good knee bending.
Lahore, Punjab ProvinceAges 18–40 - NCT07124494Recruiting
Anesthesia type and recovery after knee replacement
This study compares two types of anesthesia for total knee replacement to see which helps with pain, movement, and satisfaction after surgery. If you are scheduled for a knee replacement and are willing to have a spinal or epidural anesthesia, you may be able to join.
Konya, MeramAges 18 years+ - NCT04526093Recruiting
Study of medical cannabis using patient symptom reports
This study looks at how medical cannabis affects symptoms like pain, epilepsy, sleep, and anxiety or depression, based on what patients report over time. It may help researchers understand what works in real life when people use verified medical cannabis products.
Toronto, OntarioAges 19 years+ - NCT07188779RecruitingPhase 2
Impact of a special gel on tonsillectomy recovery in children
This trial tests whether applying a special gel called RADA16 to the surgical site after tonsillectomy (removal of tonsils) can help children heal better and with less pain. It may offer a new way to improve recovery after this common surgery.
Livingston, New JerseyAges 3–17 - NCT07717021Enrolling by invitation
Patient feedback after umbilical hernia surgery
This study looks at how patients feel and function after surgery to fix a small, first-time umbilical hernia (a bulge near the belly button). Your feedback will help doctors understand what matters most to people like you.
Karlskrona, Blekinge CountyAges 18–75 - NCT07716215Recruiting
Which exercise helps sacroiliac joint pain more?
This study compares two types of exercises—core stability exercises versus hip-strengthening exercises—to see which works better for reducing pain and improving function in people with long-term sacroiliac joint dysfunction. It may help you find a targeted treatment for your chronic pelvic or low back pain.
RawalpindiAges 25–55 - NCT07717151Recruiting
Preventing long-term pain after surgery for chronic opioid users
This trial tests a method to prevent chronic pain after surgery in people who already take opioids regularly. It may help reduce long-term pain and improve recovery.
AmiensAges 18 years+ - NCT07251959Enrolling by invitation
Exercise vs. exercise plus manual therapy for chronic back pain
This study tests whether a workplace exercise program, with or without hands-on manual therapy, can help reduce chronic spinal pain in desk workers. It is designed for UCAM University staff who have had persistent back pain for at least 3 months.
Murcia, MurciaAges 18 years+ - NCT07305025Recruiting
Acupuncture for pelvic pain in endometriosis
This trial tests if electro-acupuncture can help reduce pelvic pain in women with suspected endometriosis. You would receive acupuncture treatments and be followed to see if your pain improves.
TrondheimAges 18–45 - NCT07702344Recruiting
Shift work and your body's daily rhythm
This study looks at how shift work affects your body's natural daily rhythm (circadian rhythm) and overall health. It may help find ways to support the health of shift workers like you.
IstanbulAges 18–65 - NCT07713108Recruiting
Pelvic floor muscle function and endometriosis pain study
This study looks at how pelvic floor muscles work in women with endometriosis-related pelvic pain compared to healthy women. It aims to understand if muscle function is linked to pain, which could help improve treatments.
Pécs, BaranyaAges 18–48 - NCT07712913RecruitingPhase 3
Pregabalin for nerve pain from diabetes or shingles
This trial tests an extended-release version of pregabalin (a pain medication) for people with long-term nerve pain caused by diabetes or shingles. It aims to see if this once-daily pill can reduce pain with fewer side effects.
Salvador, Estado de BahiaAges 18–75 - NCT07715591Recruiting
Relaxing breathing during awake cataract surgery
This study tests a special breathing and pain education program to help you stay calm and comfortable during cataract surgery while you are awake. It may reduce pain and anxiety without extra medicine.
Los Angeles, CaliforniaAges Any age - NCT07356362Recruiting
Laser therapy for numbness and itching on the back
This trial tests whether a high-power laser can help relieve the itching, burning, and numbness on one side of the upper back caused by a condition called notalgia paresthetica. It may be an option if you have had these symptoms for at least 3 months and other causes have been ruled out.
UşakAges 18–65 - NCT07517679RecruitingPhase 4
Methadone for Pain After Spine Surgery
This study tests whether methadone, an opioid medication, can safely manage pain after elective spine surgery. Researchers want to see if it works well and is safe for patients staying overnight in the hospital after their procedure.
Lexington, KentuckyAges 18–120 - NCT07077148Recruiting
Swaddling or tucking for comfort on CPAP
This study tests whether gentle swaddling or a technique called 'facilitated tucking' (holding the baby in a curled, comfortable position) helps premature babies feel more comfortable while they are on nasal CPAP breathing support. The goal is to see if these simple comfort measures can reduce stress and improve care for late preterm infants.
RizeAges Any age - NCT07426562Recruiting
Stretching vs. Dry Needling for Tight Hamstrings in Chronic Back Pain
This trial tests two treatments for tight hamstrings in people with long-lasting low back pain: a special stretch and dry needling (thin needles placed in trigger points). It aims to find which helps reduce tightness and pain.
Peshawar, Khyber PakhtunkhwaAges 20–50 - NCT07474610Recruiting
Belly muscle and arm function in chronic low back pain
This study looks at how a deep belly muscle (transversus abdominis) relates to arm and shoulder function in people with long-term low back pain. It may help understand why some people have trouble with upper body movements.
AnkaraAges 18–45 - NCT07711795Recruiting
Mindfulness texts for pain and medication
This study tests if text messages with meditation tips and medication reminders can help people with chronic pain stick to their treatment for opioid use. If you recently started or restarted methadone or buprenorphine, this might be for you.
Albuquerque, New MexicoAges 18 years+ - NCT07712211Recruiting
Pain Catastrophizing and Nausea After Gallbladder Surgery
This study looks at how a person's tendency to focus on and feel overwhelmed by pain (called 'pain catastrophizing') might affect nausea and vomiting after gallbladder surgery. If you are scheduled for keyhole gallbladder removal, you may help doctors better predict and prevent post-surgery nausea.
TrabzonAges 18–65 - NCT07709975Recruiting
Pain relief and early movement for older ICU patients
This study tests different ways to manage pain and help older patients get moving again sooner after major surgery. If you are 65 or older and in the ICU, this trial may help you recover more comfortably and quickly.
Istanbul, IstanbulAges 65 years+
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,756 recruiting pain medicine studies from the U.S. registry right now, out of 6,776 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.