Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06668623Recruiting
Reiki for nerve pain and sleep in diabetic neuropathy
This trial tests if Reiki, a gentle hands-on energy therapy, can reduce nerve pain and improve sleep in people with diabetic neuropathy. It may offer a non-drug option for managing symptoms.
Kayseri, KocasinanAges 18–70 - NCT06815809Recruiting
Floor training to reduce fear of falling
This study tests a simple program where you learn to safely get down to and up from the floor to help manage fear of falling. It is for healthy adults who want to feel more confident handling a fall.
Karlstad, Värmland CountyAges 18–64 - NCT06821217Recruiting
App-based support for endometriosis quality of life
This trial tests whether using a smartphone app can improve quality of life for people with endometriosis. You'll use the app to track symptoms and get support, and researchers will see if it helps you feel better.
BernAges 18 years+ - NCT06828016Recruiting
Foot Reflexology for Chronic Low Back Pain
This study tests whether foot reflexology—a gentle massage of the feet—can help relieve chronic low back pain that has lasted more than 12 weeks. It is a safe, non-drug approach that may be a good option for people looking for a natural way to manage their pain.
New Taipei CityAges 18–100 - NCT05985850RecruitingPhase 2
Can cannabis help with opioid addiction treatment?
This trial tests if adding a specific cannabis product to standard methadone treatment helps people with opioid use disorder. It's for adults over 25 who recently started methadone and have used cannabis before.
Vancouver, British ColumbiaAges 25 years+ - NCT06320041RecruitingPhase 4
Oliceridine for pain after orthopedic surgery
This trial tests a new painkiller called oliceridine for moderate to severe pain after orthopedic surgery. It may help you recover more comfortably with fewer side effects.
Yiwu, ZhejiangAges 18–100 - NCT06446830Recruiting
Vitamin B complex for pain relief after cesarean in ICU
This trial tests whether adding vitamin B complex to standard pain medicine can improve pain control after a cesarean section in critically ill women. It aims to find a safer, effective way to manage pain without relying too much on strong opioids.
Cairo, EgyptAges Any age - NCT06534710Recruiting
Electronic moxibustion for pain and healing after brain surgery
This trial tests if a special heating device (electronic moxibustion) can reduce pain and help wounds heal faster after brain surgery. It may be an option if you are recovering well three days after surgery.
Yiwu, ZhejiangAges 18–80 - NCT07394673Recruiting
Nerve block for pain after shoulder surgery
This trial tests a new ultrasound-guided nerve block for pain relief after shoulder surgery. It aims to improve comfort and reduce the need for pain medications.
BursaAges 18–65 - NCT07393958Recruiting
Can food supplements improve quality of life with endometriosis pain?
This study tests if a food supplement (Doliral®) can help reduce pelvic pain and improve daily life in women with endometriosis. It is for those with mild to moderate endometriosis (stages I–III) who have had pain for at least three months but do not need surgery right now.
BarcelonaAges 18 years+ - NCT07392333Recruiting
Nerve ablation for chronic low back pain
This study tests a treatment that uses radiofrequency energy to target specific nerves in the spine that may be causing your low back pain. If you qualify, you would receive the OptaBlate BVN procedure and be followed over time to see how well it works.
Fort Lauderdale, FloridaAges 22 years+ - NCT06830876Recruiting
Testing muscle stimulator for pain and function after leg amputation
This trial tests if a noninvasive electrical stimulator (NMES) placed on the residual leg can reduce pain and improve muscle and function in people with a below-knee amputation. It aims to offer a drug-free option for managing chronic limb pain.
Pittsburgh, PennsylvaniaAges 18–100 - NCT07393139Recruiting
Pain after arm or leg amputation
This study looks at pain in the days right after a limb amputation surgery. It aims to better understand and manage early pain, which could help improve recovery.
BolognaAges 18 years+ - NCT07396051Recruiting
Exercise program for frail older adults after back fusion surgery
This trial tests whether a special exercise program after lower back fusion surgery can help prevent complications in older adults who are frail. If you are 75 or older and having your first small back fusion, this rehab might help you recover better.
Beijing, Beijing MunicipalityAges 75 years+ - NCT07394816Recruiting
Can ultrasound-guided pain blocks reduce lung complications after abdominal surgery?
This study tests whether using ultrasound-guided pain blocks (fascial plane blocks) during major abdominal surgery can reduce lung complications after surgery, especially in older adults. It may offer better pain control and faster recovery.
Yenimahalle, AnkaraAges 65 years+ - NCT07390279Recruiting
Radiofrequency treatment for shingles-related nerve pain
This study tests a safe, non-surgical treatment called transcutaneous pulsed radiofrequency to see if it can help reduce nerve pain that continues after shingles. It targets the painful area through pads on the skin.
Istanbul, IstanbulAges 18 years+ - NCT07397117Recruiting
Ultrasound-guided nerve block for sciatica pain
This trial tests if an ultrasound-guided nerve block can provide better pain relief for sciatica compared to standard care. If you have severe leg pain from sciatica, this study might help you find effective pain control.
San Francisco, CaliforniaAges 18 years+ - NCT07393672RecruitingPhase 2
Cannabinoids for menopause symptoms
This trial tests if hemp-derived cannabinoids can help with menopause symptoms like hot flashes and sleep issues. It may be an option if you are between 40 and 60, no longer having monthly periods or starting the transition, and can use a smartphone for virtual visits.
Pullman, WashingtonAges 40–60 - NCT07392099Recruiting
Comparing a single pain relief class vs. usual care after orthopedic surgery
This study tests whether a single, 1-hour class on pain management (called Empowered Relief) can help people recover better after orthopedic surgery (like hip or knee replacement) compared to usual care. It is for people who have had moderate to severe pain for at least 3 months and are fluent in French.
Sherbrooke, QuebecAges 18 years+ - NCT07397234Recruiting
Awake breathing tube placement study
This study tests two ways to numb the neck for placing a breathing tube while you're awake. It might help if you have a difficult airway that makes regular intubation harder.
Nanjing, JiangsuAges 18–85 - NCT07391930Recruiting
High intensity exercise for period pain
This study tests if high-intensity interval training (short bursts of intense exercise) can help reduce period pain. It is for people who have not given birth and experience regular period pain.
Alcalá de Henares, MadridAges 18–40 - NCT07396545Recruiting
Comparing two types of nerve blocks for pain after stomach cancer surgery
This trial looks at two different pain-blocking injections (nerve blocks) to see which one works better for pain after keyhole stomach cancer surgery. If you are having this type of surgery, joining could help us learn which block gives you better pain relief.
Yinchuan, NingxiaAges 18 years+ - NCT07396558Recruiting
Nerve block for lung cancer chest pain
This study tests a new way to deliver pain medicine through a small tube (catheter) placed under the skin near your back, so you can get long-lasting relief from cancer-related chest pain at home. It is for people with advanced lung cancer whose current pain treatments are not enough.
HanoiAges 18 years+ - NCT07395934Recruiting
Comparing two epidural methods for labor pain relief
This study compares two ways of giving epidural pain relief during labor: a programmed intermittent bolus (PIEB) versus a continuous infusion (CEI). The goal is to see which method works better for managing pain in vaginal delivery.
Da NangAges 18–40
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.