Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06856642Recruiting
Comparing belly drawing exercises with ultrasound for chronic back pain
This study compares two types of physical therapy for chronic low back pain: one uses real-time ultrasound to help you learn a special belly-drawing maneuver, the other is standard physical therapy. The goal is to see which method reduces pain better.
BoluAges 18–65 - NCT06861751Recruiting
Smartphone overuse and jaw proprioception in teens
This trial looks at how heavy smartphone use affects neck posture, neck muscle endurance, and jaw awareness in teenagers aged 17-19. It aims to understand if long-term phone use is linked to these physical changes.
Al MansurahAges 17–19 - NCT03976154Recruiting
Testing a fixation method to reduce thoracic epidural movement
This trial studies whether a new way of securing a thoracic epidural line keeps it from shifting during surgery. You might benefit if your surgical care includes a thoracic epidural and you can safely receive this type of anesthesia.
Salt Lake City, UtahAges 18 years+ - NCT05824832RecruitingPhase 4
Buprenorphine, clonidine, and steroid to extend arm nerve block
This study tests whether adding certain medicines (buprenorphine, clonidine, and a steroid) to an arm “nerve block” during shoulder surgery can help the numbness last longer and improve comfort afterward. It is for adults having shoulder arthroscopy and compares how long the nerve block works.
Maywood, IllinoisAges 18 years+ - NCT07329361Recruiting
Frozen platelet-rich plasma injections for knee osteoarthritis
This trial tests whether frozen platelet-rich plasma (PRP) injections into the knee can safely reduce pain and improve function in people with knee osteoarthritis. It's for those with mild to moderate knee arthritis who haven't had certain recent knee treatments.
Vitoria-Gasteiz, Araba/ÁlavaAges 40–85 - NCT07326943Recruiting
Finding the Right Dose of Ropivacaine for Arm Surgery
This study is for people having hand or forearm surgery. It aims to find the smallest effective dose of a numbing medicine (ropivacaine) that works well to block pain during the procedure.
Taiyuan, ShanxiAges 18–60 - NCT07332390Recruiting
Exercise study for chronic non-specific low back pain
This study compares two types of exercise programs—moderate load eccentric core exercises and Pilates—to see which is more effective for people with long-lasting low back pain that isn't caused by a specific medical condition.
Islamabad, Punjab ProvinceAges 18–45 - NCT07333040Recruiting
Energy therapy vs. surgery for grade III hemorrhoids
This trial compares two less invasive energy-based treatments with standard surgery for people with grade III hemorrhoids. If you are between 18 and 75 and your hemorrhoids cause significant symptoms, this study may help find a gentler option.
TaoyuanAges 18–75 - NCT07327905Recruiting
Lidocaine or dexmedetomidine for pain during weight-loss surgery
This trial compares two medicines given through an IV during sleeve gastrectomy (weight-loss surgery) to see which provides better pain control. It may help patients have a smoother recovery with less discomfort.
AlexandriaAges 20–50 - NCT07329426Recruiting
Muscle energy therapy with mobilization for sacral torsion
This trial tests if combining muscle energy therapy with spinal mobilization can relieve pain and correct misalignment in people with a twisted pelvic bone (sacral torsion). It may help reduce pain and improve mobility.
Islamabad, Punjab ProvinceAges 22–44 - NCT07327138Recruiting
Laughter and yoga for kids with leukemia after chemo
This study tests if fun yoga and laughter exercises at home can help children aged 2-10 with a type of leukemia feel less pain after chemotherapy. It's designed to be gentle and safe, with a parent or guardian joining in.
SidonAges 2–10 - NCT07329023Recruiting
Acupressure for Knee Arthritis in Older Chinese Adults
This trial tests whether learning self-administered acupressure (a type of massage using fingertips) can help older Chinese adults with knee arthritis manage their pain and stiffness without medication. If you join, you will receive training in a community setting and use a smartphone app to track your progress.
KowloonAges 60 years+ - NCT07327554Recruiting
Lumbar movement fluidity study for chronic low back pain
This trial uses wearable sensors to measure how smoothly your lower back moves before and after rehabilitation. It aims to see if rehabilitation improves movement fluidity in people with chronic low back pain.
MontpellierAges 18–65 - NCT07327593Recruiting
Exercise and pain relief in stroke survivors
This study looks at whether exercise can reduce pain sensitivity in people who have had a stroke and in healthy individuals. Participants will pedal on a stationary bike to see how their pain perception changes.
Madrid, MadridAges 18 years+ - NCT07325110Recruiting
Teens with chronic pain: yoga in occupational therapy
This study looks at whether adding yoga to occupational therapy helps teens with chronic pain better understand their body's signals. It aims to improve daily function and well-being.
Hartford, ConnecticutAges 11–21 - NCT07325994Recruiting
Pain control during hysteroscopy for women with infertility
This trial tests if using calming words (verbal analgesia) during a hysteroscopy can reduce pain compared to standard care. It is for women with primary infertility who need this procedure to check the uterus.
GizaAges 18–40 - NCT07325851Recruiting
Ozone therapy for chronic pain when other options fail
This study is testing ozone therapy as a palliative treatment for people with chronic pain who haven't found relief from other options. It aims to see if adding ozone can improve pain and quality of life.
Las Palmas de Gran Canaria, Las PalmasAges 18 years+ - NCT07331441Recruiting
Nerve block for pain relief after major upper abdominal surgery
This trial tests a nerve block given near the ribs to see if it reduces pain after surgeries like gastric, liver, gallbladder, or pancreatic surgery. It may help you need less pain medicine after the operation.
ShanghaiAges 18–85 - NCT07326774Recruiting
Ultrasound-guided pain block for back surgery recovery
This trial tests whether a special pain block (Quadro-Iliac Plane Block) given before back surgery can reduce pain after the operation. The goal is to help patients feel more comfortable and need fewer painkillers.
Istanbul, IstanbulAges 18–65 - NCT07326163Enrolling by invitation
Peppermint oil aromatherapy for fibromyalgia pain relief
This study tests whether smelling peppermint oil can help reduce pain and improve daily function in people with fibromyalgia, while also looking at cost. It uses a simple, non-invasive method (aromatherapy) to see if it can be a helpful addition to your current care.
Bilecik, BilecikAges 18 years+ - NCT07329478Recruiting
Muscle Techniques for Neck Pain Strength and Endurance
This study compares two gentle muscle techniques to see which better strengthens neck muscles and improves endurance in people with mechanical neck pain (pain not caused by a serious disease or injury). It may help you move your neck more easily and reduce discomfort.
Islamabad, Punjab ProvinceAges 19–44 - NCT07331012Recruiting
Flywheel exercise for better basketball skills in teens
This study tests if upper body flywheel exercises can improve basketball skills, muscle oxygenation, and reduce fatigue in adolescent male basketball players. Flywheel exercises use a spinning wheel to create resistance during movement.
IğdırAges 10–18 - NCT07328360Recruiting
High-power laser for outer thigh nerve pain
This study tests whether a special high-power laser can reduce nerve pain on the outer thigh (called meralgia paresthetica). It's for people who have had this pain for at least 3 months and are not on blood thinners or pregnant.
UşakAges 18–65 - NCT07326137Recruiting
Pain relief and first-line treatment for advanced bile duct or pancreatic cancer
This study tests combining standard first-line cancer therapy with a nerve block to reduce pain in people with advanced bile duct or pancreatic cancer. It aims to see if this combination can improve pain control and quality of life.
Wuhan, HubeiAges Any age
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.