Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07333040Recruiting
Energy therapy vs. surgery for grade III hemorrhoids
This trial compares two less invasive energy-based treatments with standard surgery for people with grade III hemorrhoids. If you are between 18 and 75 and your hemorrhoids cause significant symptoms, this study may help find a gentler option.
TaoyuanAges 18–75 - NCT07328126Recruiting
Muscle energy technique for low back pain relief
This trial tests a gentle muscle stretching method (muscle energy technique) on the latissimus dorsi muscle to see if it reduces pain, improves daily function, and increases spine movement in people with long-term low back pain.
Rawalpindi, Punjab ProvinceAges 30–55 - NCT07330063RecruitingPhase 2
Pain relief injection after laparoscopic stomach cancer surgery
This trial tests an injection called Anrikefon to see if it can safely and effectively reduce pain after surgery to remove part of the stomach for cancer. The surgery is done through small cuts (laparoscopic), and this treatment is given after surgery to help with pain while you recover.
Tianjin, Tianjin MunicipalityAges 18–75 - NCT07326943Recruiting
Finding the Right Dose of Ropivacaine for Arm Surgery
This study is for people having hand or forearm surgery. It aims to find the smallest effective dose of a numbing medicine (ropivacaine) that works well to block pain during the procedure.
Taiyuan, ShanxiAges 18–60 - NCT07327554Recruiting
Lumbar movement fluidity study for chronic low back pain
This trial uses wearable sensors to measure how smoothly your lower back moves before and after rehabilitation. It aims to see if rehabilitation improves movement fluidity in people with chronic low back pain.
MontpellierAges 18–65 - NCT07333417Recruiting
Rigid taping for acromioclavicular joint degeneration
This study tests whether a special rigid tape applied to the shoulder can reduce pain and improve function in people with acromioclavicular (AC) joint degeneration. The AC joint is where your collarbone meets the top of your shoulder blade, and this condition can cause pain and stiffness.
Ankara, AnkaraAges 18–65 - NCT07332390Recruiting
Exercise study for chronic non-specific low back pain
This study compares two types of exercise programs—moderate load eccentric core exercises and Pilates—to see which is more effective for people with long-lasting low back pain that isn't caused by a specific medical condition.
Islamabad, Punjab ProvinceAges 18–45 - NCT07332845Recruiting
Neck and hamstring therapy for chronic pain
This trial tests a special exercise technique that combines shoulder blade and pelvis movements to see if it helps people with long-term neck pain and tight hamstrings.
Karachi, SindhAges 18–40 - NCT07329023Recruiting
Acupressure for Knee Arthritis in Older Chinese Adults
This trial tests whether learning self-administered acupressure (a type of massage using fingertips) can help older Chinese adults with knee arthritis manage their pain and stiffness without medication. If you join, you will receive training in a community setting and use a smartphone app to track your progress.
KowloonAges 60 years+ - NCT07329309Recruiting
Breathing exercises for pain after cesarean
This study tests if a gentle breathing technique called Pranayama can help reduce pain after a planned cesarean. It compares the breathing exercise to usual care to see if it improves recovery.
Konya, KonyaAges 18–35 - NCT05314491Recruiting
Follow-up study after knee replacement with a specific implant
This study follows people after they get a total knee replacement using the Multigen Plus system, sometimes with special cone pieces. It looks at how well the implant performs over time and whether results meet expectations.
GuimarãesAges 18 years+ - NCT06224959Recruiting
Migraine and nerve pain in osteoarthritis study
This study looks at whether people with osteoarthritis also have migraine headaches or nerve pain. Researchers want to better understand these connections to improve treatment.
Clermont-Ferrand, FranceAges 18 years+ - NCT06595329RecruitingPhase 1
Pain relief after kidney cancer surgery: epidural vs spinal opioids
This trial compares two ways to manage pain after open kidney cancer surgery: an epidural (a thin tube placed near your spine) versus a single spinal injection of opioids. Both aim to control pain, but the study wants to see which method works better, with fewer side effects.
SplitAges 18 years+ - NCT05347069RecruitingPhase 4
Aspirin study for people with stable heart artery disease
This trial tests whether daily aspirin is safe and effective for people who have stable (chronic) coronary artery disease but cannot have procedures to open blocked arteries. It may help reduce future heart problems, while also checking for side effects and risks from aspirin.
KyotoAges 20 years+ - NCT05006859Recruiting
Wheelchair positioning for people with neuromuscular conditions
This trial looks at improving wheelchair positioning for people with neuromuscular diseases. Better positioning may help comfort, safety, and support day-to-day movement in a wheelchair.
AincourtAges 8 years+ - NCT06831604Recruiting
Nerve blocks for clavicle surgery pain relief
This trial compares two types of nerve blocks to see which provides better pain control during and after clavicle fracture surgery. It may help patients have a smoother recovery with less pain.
Tanta, El-GharbiaAges 18–65 - NCT06864884RecruitingEarly Phase 1
Study of ARC-001 for wisdom teeth removal
This trial tests a new medicine called ARC-001 in people who are scheduled to have their wisdom teeth taken out. The goal is to see if it's safe and how it affects pain and healing.
Salt Lake City, UtahAges 18–55 - NCT06869928Recruiting
Pain and irritability pathway for children with neurological conditions
This study tests a special care plan for children who have both a significant neurological condition and unexplained pain or irritability. The goal is to help families and doctors work together to better understand and manage these distressing symptoms.
Vancouver, British ColumbiaAges 6 months–18 years - NCT06869668Recruiting
Chronic low back pain and quality of life study
This study looks at how long-term back pain affects your daily life, physical abilities, and how you feel about moving. It aims to find links between pain, fear of movement, and overall well-being.
Istanbul, BuyukcekmeceAges 18–50 - NCT07324499Recruiting
Dexamethasone with nerve block for shoulder surgery
This trial tests if adding dexamethasone to a standard numbing medicine (bupivacaine) affects how much of the medicine stays in your blood. It may help improve pain relief after shoulder surgery.
SantiagoAges 18–90 - NCT07319273Recruiting
Child Life Services for Kids' Allergy Skin Tests
This study is testing whether a special program called 'Child Life Services' can help children feel more comfortable and less anxious during a skin prick test, which is a common allergy test. The goal is to make the experience easier for kids and their families.
ShanghaiAges 1–18 - NCT07317271Recruiting
Virtual reality for burn symptoms
This trial tests a virtual reality program to help with symptoms like pain, trouble sleeping, and itching after a burn injury. You can join from home using your own device.
Baltimore, MarylandAges 18 years+ - NCT07316166RecruitingPhase 4
Nerve Block With or Without Extra Medicine for Hip Replacement
This trial compares two types of nerve blocks for pain relief after total hip replacement. One block uses a standard numbing medicine, and the other adds a medication (dexmedetomidine) that may extend the pain relief. The goal is to see which approach works better for managing pain after surgery.
Providence, Rhode IslandAges 18–80 - NCT07324343Recruiting
Education for shoulder pain: which patients benefit most?
This study tests whether patients with different types of shoulder pain respond better to learning about their condition through education alone. You will receive information and advice to help you manage your pain without injections or surgery.
IstanbulAges 18–65
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.