Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT07050277RecruitingPhase 3
Morphine for bladder issues after knee replacement
This study tests whether adding morphine to spinal anesthesia can reduce trouble urinating after a second knee replacement surgery. It may help you avoid needing a catheter after surgery.
Toronto, OntarioAges 21 years+ - NCT07050212Recruiting
Sedation study for children having tonsil surgery
This study tests three different medicines to help young children relax before surgery to remove their tonsils and adenoids. It aims to find which medicine works best and is safest for kids ages 2 to 5.
Wuhan, HubeiAges 2–5 - NCT07048366Recruiting
Mindfulness in a museum for fibromyalgia pain relief
This study tests whether a mindfulness program held in a museum setting can help women with fibromyalgia feel less pain and improve their quality of life. You would attend sessions in a museum and practice mindfulness techniques.
Chieti, AbruzzoAges 18–60 - NCT07051265Enrolling by invitation
Pain relief for head and neck cancer patients using TENS or acupressure
This study compares two non-drug methods—TENS (a mild electrical device) and acupressure (gentle finger pressure on specific points)—to help manage pain in people with head and neck cancer. If you have cancer-related pain and need medication, you may be able to join.
Kaohsiung CityAges 20–100 - NCT07051772Recruiting
Predicting success in back pain rehab
This study looks for factors that help people with long-term low back pain succeed in rehabilitation programs. Researchers will track participants during their rehab to learn what works best.
Clermont-Ferrand, AuvergneAges 18–65 - NCT07045974Recruiting
Stretching and mobilization for neck pain
This trial tests if a specific stretching and mobilization technique (Mulligan) reduces neck pain that travels down the arm. It may help if you have nerve-related neck pain confirmed by simple physical tests.
Peshawar, KPKAges 20–50 - NCT07054775RecruitingPhase 4
Comparing itching after two doses of spinal morphine in C-section
This study compares two low doses of morphine given during spinal anesthesia for planned cesarean sections, to see which causes less itching. It aims to find a safer way to manage pain after birth.
Khon KaenAges 18–45 - NCT07048769RecruitingPhase 4
Pain relief shot for saline ultrasound of the uterus
This trial tests if a numbing injection in the cervix reduces pain during a saline ultrasound that checks the uterus and fallopian tubes. It might help make the procedure more comfortable for you.
Hartsdale, New YorkAges 18–50 - NCT07047846Recruiting
Bowen technique vs. soft tissue therapy for frozen shoulder pain
This study compares two massage-like treatments (Bowen technique and dynamic soft tissue mobilization) to see which better reduces pain, improves movement, and helps daily function in people with frozen shoulder. It only includes diabetic patients with specific stages of frozen shoulder.
Lahore, Punjab ProvinceAges 50–80 - NCT07051577Recruiting
Brain-Based Training for Young Archers
This study tests a special brain-based training program for young archers aged 15–18. The goal is to see if these exercises can improve your shooting accuracy and how your muscles work.
Istanbul, IstanbulAges 15–18 - NCT07054801RecruitingPhase 2
Testing lidocaine and steroids for headache after bleeding stroke
This study tests whether giving two medicines (lidocaine and methylprednisolone) directly into the artery during a routine brain vessel procedure can help relieve headaches caused by a bleeding stroke. It may help find a new treatment for this type of headache.
San Francisco, CaliforniaAges 18 years+ - NCT07040267Recruiting
Does phone use change thumb strength and feeling?
This study looks at how smartphone use affects the strength and feeling in your thumb. If you are a young university student who uses a smartphone daily, you may help researchers understand if heavy phone use changes your thumb muscles or senses.
Istanbul, ÜsküdarAges 18–30 - NCT07039812Recruiting
Virtual Reality for Pain During Dressing Changes After Heart Surgery
This study tests if using virtual reality or an eye mask during wound dressing changes can help reduce pain and anxiety after coronary artery bypass surgery. It aims to find a drug-free way to make dressing changes more comfortable.
Istanbul, MarmaraAges 18–65 - NCT07044323Recruiting
Virtual reality for phantom limb pain after leg amputation
This study tests whether using virtual reality at home for 30 minutes a day can reduce phantom limb pain after a leg amputation. It aims to improve how your brain handles pain signals.
Philadelphia, PennsylvaniaAges 18–100 - NCT07041736Recruiting
Laser combo for pain and infection after root canal
This trial tests if using ultrasound and a 980 nm diode laser together can reduce pain and kill bacteria better after a root canal. It may help if you have a tooth with an infection at the tip, but no symptoms.
CairoAges 20–35 - NCT07036393Recruiting
Acupuncture vs. TENS for pain after upper belly surgery
This trial compares two non-drug treatments — acupuncture and TENS — to see which works better for pain after upper abdominal surgery. You might join to help find a gentler option for recovery.
Al MansurahAges 20–45 - NCT07036315Recruiting
Can music help manage pain?
This study uses music to see how the brain processes pain. It may help develop new, non-drug ways to manage pain.
Charlottesville, VirginiaAges 18–65 - NCT07040605Recruiting
Neck exercises for chronic pain
This study tests a special set of exercises for your neck muscles to help with chronic neck pain. It focuses on strengthening deep muscles and improving how your body senses neck movement.
Cairo, Giza GovernorateAges 20–40 - NCT07038980Recruiting
Smartphone use and neck muscle health study
This study looks at how smartphone addiction relates to neck muscle health. You may be able to join if you are a young adult who uses a smartphone and has no known neck or health issues.
Istanbul, ÜsküdarAges 18–30 - NCT07039071Recruiting
Laceback study for orthodontic treatment outcomes
This trial tests whether a technique called laceback improves treatment results for people getting braces. It looks at tooth movement and patient comfort.
Kuantan, PahangAges 15 years+ - NCT07035015Recruiting
Virtual reality vs mannequin for learning a hip nerve block
This study compares learning a specific nerve block (for the hip/upper thigh) using a self-guided virtual reality headset versus a traditional mannequin. It is for doctors and trainees at The Ottawa Hospital who want to improve their ultrasound skills for this procedure.
Ottawa, OntarioAges Any age - NCT07036237Enrolling by invitation
Comparing pain relief rinses after root canal
This trial tests whether rinsing the tooth with either tramadol (a pain reliever) or dexamethasone (a steroid) after a root canal reduces pain better. It is for people with a single-rooted tooth that has a very painful, inflamed nerve.
Karachi, SindhAges 18–50 - NCT07038434Recruiting
Using artificial intelligence to measure pain in chronic pain patients
This study uses artificial intelligence to better understand and measure pain in people with chronic pain. The goal is to develop smarter ways to assess pain automatically, which could lead to better treatment.
Salerno, ItalyAges 18 years+ - NCT07034300RecruitingPhase 4
Comparing lidocaine with and without dexmedetomidine for arm surgery
This trial tests whether adding dexmedetomidine to lidocaine works better for numbing the arm during surgery. Patients get numbing medicine through a special IV in the arm while the surgery is happening.
Lahore, Punjab ProvinceAges 18–60
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.