Pain medicine
Pain clinical trials
Chronic and acute pain, and the conditions that cause it. We’re tracking 3,578 recruiting studies in this area right now.
By phase
- Not applicable2,954
- Phase 4240
- Phase 2129
- Phase 3103
- Phase 193
- Phase 2/Phase 337
- Phase 1/Phase 222
Top conditions
Leading sponsors
- Riphah International University84
- Cairo University59
- Beijing Tiantan Hospital34
- Tanta University33
- Ain Shams University28
- Foundation University Islamabad28
- Mayo Clinic25
- VA Office of Research and Development23
- Hacettepe University22
- Stanford University21
Where studies are running
- California151
- New York79
- Massachusetts65
- Florida64
- Texas50
- North Carolina41
- Illinois40
- Maryland39
- Ohio39
- Minnesota37
Recruiting studies3,578 total
- NCT06630819Recruiting
Comparing different volumes of numbing medicine for tooth removal
This study tests whether using a smaller amount of a numbing medicine (articaine) works as well as the usual amount for numbing the area before removing a lower back tooth. It aims to make the procedure more comfortable and efficient.
Buraidah, Al QassimAges 18 years+ - NCT07028528RecruitingPhase 2
Study of Levagen+ for diabetic nerve pain
This trial tests if Levagen+ (a supplement) can reduce nerve pain caused by diabetes. It is for people with type 1 or type 2 diabetes who have significant nerve pain in their feet or legs.
Fortitude Valley, QueenslandAges 18–75 - NCT06995248Recruiting
Laughter yoga for cancer patients and caregivers
This trial explores whether laughter yoga can help reduce pain and fatigue and improve overall well-being for people with cancer and the people who care for them.
AnkaraAges 18–65 - NCT07025993Recruiting
Muscle technique vs. exercises for upper crossed syndrome
This trial compares two treatments for upper crossed syndrome (a condition causing neck and shoulder tightness) to see which works better for recent neck pain. It tests a hands-on muscle energy technique versus stabilization exercises for your neck and shoulder blades.
Lahore, Punjab ProvinceAges 18–65 - NCT07028151Enrolling by invitation
Massage versus standard care for teeth grinding
This study tests whether a classical massage can help relieve jaw tension and other symptoms of teeth grinding (bruxism) in college students, compared to standard treatments. If you grind or clench your teeth and are between 18 and 27, this might be a non-invasive option to explore.
Bartın, AnkaraAges 18–27 - NCT07026058Recruiting
Sound wave therapy for mechanical low back pain
This study tests whether adding sound wave therapy to standard physical therapy helps adults with long-lasting low back pain. It is for people aged 18 to 45 whose pain stays above the knee.
Lahore, Punjab ProvinceAges 18–45 - NCT07033104Recruiting
Adding calcitonin to numbing medicine for C-section pain relief
This study tests if adding a medication called calcitonin to the usual numbing medicine (bupivacaine) can provide better pain relief after a cesarean section. It is for women who are having a planned C-section under spinal anesthesia.
Tanta, Gharbia GovernorateAges Any age - NCT07024199RecruitingPhase 4
Pain relief for children with acute pancreatitis
This trial compares three common pain relievers (paracetamol, ibuprofen, and metamizole) to see which works best for children with acute pancreatitis. It aims to help your child feel better faster with fewer side effects.
WarsawAges 3–18 - NCT07026786Recruiting
Mindfulness for recovery after colorectal surgery
This study tests whether adding mindfulness sessions to your standard recovery plan helps you heal better after bowel surgery. You'll use a phone or tablet app to guide your mindfulness practice during your hospital stay.
Cleveland, OhioAges 18 years+ - NCT07033897Recruiting
Fall prevention program for people with disabilities
This study tests a program called HARP to help people with physical disabilities reduce falls and improve stability. You may join if you have had a disability for at least 5 years, live in St. Louis City, have trouble with daily tasks, and have fallen or feel unsteady.
St Louis, MissouriAges 45–64 - NCT07027631Enrolling by invitation
Comparing two treatments for chronic neck pain
This trial tests whether magnesium sulfate iontophoresis (a method that uses a mild electrical current to deliver medicine through the skin) or extracorporeal shockwave therapy (sound waves applied to the neck) works better for long-term neck pain caused by trigger points in the upper shoulder muscle.
GizaAges 18–40 - NCT07026006Recruiting
Release techniques for chronic neck pain
This study compares two hands-on treatments for people with long-lasting neck pain. It looks at whether a technique called Active Release or Strain-Counter-strain helps reduce pain and improve neck movement.
Lahore, Punjab ProvinceAges 18–45 - NCT07030582Recruiting
Online therapy for back pain and recovery after spinal fusion
This trial tests if internet-based cognitive behavioral therapy can help people recover better after lumbar fusion surgery by reducing pain, strengthening back muscles, and improving outlook on recovery. You can participate from home using WiFi.
Nantong, JiangsuAges 18–55 - NCT07028034Recruiting
Six-minute step test for chronic back pain
This trial uses a simple step test to measure how chronic low back pain affects your daily function. It may help doctors better understand your condition without needing expensive equipment.
KırşehirAges 18–65 - NCT07025668Recruiting
Different exercises for biceps tendon shoulder pain
This trial compares different exercise approaches to treat long-term pain in the biceps tendon of the shoulder. It aims to find which types of movement help relieve pain and improve function for people with certain shoulder conditions.
AnkaraAges 18–50 - NCT07023926Recruiting
Acupuncture to prevent menstrual migraine
This study tests whether acupuncture can reduce the number of migraine headaches around your period. If you often get migraines with your menstrual cycle, this treatment might help prevent them.
Beijing, Beijing MunicipalityAges 18–45 - NCT07026045Recruiting
Stretching techniques for chronic low back pain
This trial compares two gentle stretching techniques to see which one better eases chronic low back pain. It may help if you have had ongoing pain for months and are looking for a non-surgical treatment.
Lahore, Punjab ProvinceAges 18–45 - NCT07027891Recruiting
AI ECG test to rule out heart attack in chest pain patients
This study tests if an AI tool reading your ECG can quickly rule out a heart attack in people with chest pain. If you're having chest pain that might be a heart attack, but it's not a severe STEMI type, you may be able to join.
SeoulAges 18 years+ - NCT07023991Enrolling by invitationPhase 1
Dexmedetomidine with bupivacaine for children's lower abdominal surgery
This trial tests whether adding dexmedetomidine (a sedative) to bupivacaine (a numbing medicine) improves pain relief from a nerve block in young children having lower belly surgery. The goal is to see if the combination provides better or longer-lasting pain control.
Cairo, EgyptAges 1–7 - NCT07027644Recruiting
Combined therapy for chronic neck pain relief
This trial tests whether combining a muscle-relaxation technique with cupping therapy is more effective than either alone for treating chronic neck pain caused by muscle knots in the upper trapezius. Participants must have had these knots for more than 6 months.
GizaAges 18–40 - NCT07026097Recruiting
Online vs. supervised Pilates for low back pain
This study compares doing Pilates exercises online with doing them in-person under supervision. It's for people with ongoing low back pain to see which method is more effective for reducing pain and improving function.
Lahore, Punjab ProvinceAges 18–45 - NCT07026019Recruiting
Exercise for chronic mechanical neck pain
This study tests whether a home exercise program can help people with long-term neck pain caused by muscle tightness or arthritis in the neck joints. It is designed for people who cannot easily visit a clinic due to disability, living in crowded cities, or busy schedules.
Lahore, Punjab ProvinceAges 18–45 - NCT07032350Recruiting
Pain management app for dementia caregivers
This study tests a mobile app that helps family caregivers of people with dementia manage their loved one's chronic pain. It aims to see if the app is easy to use and helpful for caregivers.
Iowa City, IowaAges 18–100 - NCT07032480Recruiting
Sleep, Neck Pain, and Depression Study
This study looks at how sleep problems, neck pain, and depression might be connected in healthy young adults. It aims to help understand these common issues better.
Istanbul, ÜsküdarAges 18–28
Common questions
- How many pain clinical trials are recruiting?
- Clin2 is tracking 3,578 recruiting pain medicine studies from the U.S. registry right now, out of 6,493 we cover in this area in total.
- What does “Pain” cover here?
- Chronic and acute pain, and the conditions that cause it. We group each study into pain based on the conditions it studies, so you can scan the whole therapeutic area at once and drill into a specific condition.
- How do I find a pain trial near me?
- Use the search to filter pain studies by location and eligibility. Every Clin2 trial page explains the criteria in plain English and offers a short, optional pre-screen for a fit read — the study team makes the final decision.
Other specialties
- Cancer
- Brain & nervous system
- Heart & circulation
- Hormones & metabolism
- Mental health
- Digestive system
- Lungs & breathing
- Immune system & allergy
- Women’s health & pregnancy
- Skin
- Blood & lymphatic
- Kidney & urinary
- Infections
- Genetic & congenital
- Bones, joints & muscles
- Injuries & trauma
- Mouth & dental
- Eyes & vision
- Ear, nose & throat
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov; specialty groupings are derived from each study’s conditions. Talk with your doctor about whether a specific trial is right for you.